iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096868

Ensembl Protein ID

ENSPFOP00000025070.1

UniProt Accession

A0A096M0X9; A0A096M0X9_POEFO

Genbank Protein ID

ENSPFOP00000025070

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01014125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000000124.2	ENSPFOT00000024883.1	ENSPFOP00000025070.1
ENSPFOG00000000124.2	ENSPFOT00000000128.2	ENSPFOP00000000128.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.20e-99	331.7	528	857

Active Site

Position(s)	Description	Evidence
826	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           +sdlkk+l+vef+gE+g+d gGv++ef++l+++e++n d+g+f+y+++ k  ++ n++s     e++  ++++G++lg+a++++ +ld+
   Q: 528  PSDLKKQLYVEFEGEQGVDEGGVSKEFFQLVLEEIFNLDIGMFTYDNDTKLFWF-NSSSL----ENEAQYTLIGIVLGLAIYNNCILDV 611
           799****************************************99998888877.55555....67999******************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvkl.. 176
           +++ ++y++l+gkk ++ dl++ +p ly+slke++e+   ++e +++ ltf+  +++++g+   ++Lk++G++ipVt+eN+++ v+l  
   Q: 612  HFPMVVYRKLMGKKGTFLDLSDSHPVLYQSLKEVLEYS-GSLE-EDMMLTFQiSHTDLFGNPVLYDLKEKGDQIPVTKENRQKVVSLrf 698
           *************************************4.4444.469999994456669***************************866 PP
   S: 177  .vveyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
            + +y+l++++++q++af++Gf  v +++ l  lF++ee+ellicG++++d+e+l+k+t+y+ggyt+ds+ i+ Fwe++++f +e+++ 
   Q: 699  yYQDYILNKSVESQFKAFKKGFLMVTNESpLKYLFRPEEVELLICGSRKLDFEALEKTTEYDGGYTKDSQIIKDFWETIHSFGEEQKRL 787
           6789**********************99934558******************************************************* PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           fLqF+Tg++r+P+gG+ +lk   ++i k++sd drlP+s+TCfn L LPeYssk++lke+Ll Ai+++kgF++
   Q: 788  FLQFTTGTDRAPVGGLGKLK---MIIAKNGSDsDRLPTSHTCFNALLLPEYSSKDKLKERLLKAITYAKGFGM 857
           ********************...8999988888**************************************97 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

RSAFVFRSPK SSLKRNFKKS KMSNRATAKR LIERYFRQLT EGCGNSSCTN EFCASCSTCQ 60
PLGNNAAAAK ALELFKVNAK LCDYYPAVES RPDEDSRLGR EMSTEEFSGT FKMDYGLSQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGACTGTCC TCCAGCCTGA GGTGCCTGAA TCCAGCCGAA TGTAAGTCTC CTCTGACTTG 60
AATCAACAAT TTTTTTGTTT GTTTCTAATA GACATGTTTT CTCGTTATTC ATATATCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gmo-038840	Gadus morhua	68.77	0.00e+00	1162.00
IUUC-Gac-042293	Gasterosteus aculeatus	74.91	0.00e+00	1265.00
IUUC-Ont-072087	Oreochromis niloticus	82.80	0.00e+00	1382.00
IUUC-Ola-086833	Oryzias latipes	82.08	0.00e+00	1323.00
IUUC-Tru-117763	Takifugu rubripes	73.52	0.00e+00	1243.00
IUUC-Tni-120640	Tetraodon nigroviridis	71.33	0.00e+00	1149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence