iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133104

Ensembl Protein ID

ENSXMAP00000016463.1

UniProt Accession

M4APR8; M4APR8_XIPMA

Genbank Protein ID

ENSXMAP00000016463

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01020368

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000016414.1	ENSXMAT00000016487.1	ENSXMAP00000016463.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.90e-116	386.8	693	1435

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++  +++++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 693  TGLVNLGNTCFMNSVIQSLSNTRELRDYFHDrAFESEINCSNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 779
           7******************************999***************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d +   de     a++++k++n+s+i+dlFqgq+ks+++c++c +vs +++p
   Q: 780  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGR--LDEvvaeeAWQRHKMRNDSFIVDLFQGQFKSKLVCPTCSKVSITFDP 864
           ********************************999932..22235666*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++                                                                          
   Q: 865  FLYLPVPLPQKQKVLSVfyfakephkkpikflvsvskensstaevlesisrsvrvksenlrlaevaknrfqriflpshsldtvspsd 951
           ************76444********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 952  mlfcfevlskdlakervvllrvqqklqvpsipiskcaaclkppvseedklkrctrcyrvgycnqhcqkthwpshkslcrpnsenvgl 1038
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1039 pflvsapesrlcyarlaqllegysrfsvnvfqppfqsgrtspetpqsrldalpmalgspdgagagdeargaggdvqagdadlespsl 1125
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1126 ppelqgeysqasaihseasgsfslsstrtkdsgfsesvsstsccsldpqaekettcekavrpeaavtgyqqpsdassghasqfyigl 1212
           *************************************************************************************** PP
   S: 186  .................................................................slqdcLesftkeeelegenkyy 207
                                                                            +l++cL+ ftk+e l  e+++y
   Q: 1213 ldsnnkeqrldekedaladvvddatlelvwknnerlkeyvlvsskeleydddpssmsetaraghfTLEQCLNLFTKPEVLAPEEAWY 1299
           *************************************************************************************** PP
   S: 208  cekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssG 293
           c+kc++++ea+k+l l++lP+vLi++LkRfsf++  +++ kin+ v+fp + Ldls+fc+ ++++ ++  +Y+L+av++H+G++ +G
   Q: 1300 CPKCQQHREASKQLLLWRLPNVLIIQLKRFSFRSFIWRD-KINDMVDFPVRnLDLSKFCIGQKDEMQQAPIYDLYAVINHYGGMIGG 1385
           ***********************************8886.**********9************************************ PP
   S: 294  HYvayvknekgk........WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           HY+ay++  ++k        W lfdDs+Vt v+e++v++   + aYvlfY+rr
   Q: 1386 HYTAYARLPSDKnsqrsdvgWRLFDDSTVTMVEESQVVT---RYAYVLFYRRR 1435
           *******9444444567788*******************...********996 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MASSGGDRVA GSETAGRRSG AQQRGGAREN GSEQTSSTSK KKQKDKANQE SREAKRAAAA 60
ANAALDGVLA EVKKDVFVDW KQNVNEVTVR LRCGDGVQRT EDINTTFTDT HCNVSFPDGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTAGAACA TTCTAGAAAC ACCGTAGACT GCGGGGGTTT CGAGTCCGGG CAGAAACAGC 60
GCAGCAGCCC GAGGCCGTGA AAGAAGCTTA GCGGCAGCCG CAGAGTGCGC TAAGGAGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND

PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2

Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND

Gene Ontology

GO:0046872--F:metal ion binding
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

xma:102225208

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	67.84	0.00e+00	1399.00
IUUC-Apl-003368	Anas platyrhynchos	71.54	0.00e+00	1419.00
IUUC-Aca-004267	Anolis carolinensis	67.21	0.00e+00	1439.00
IUUC-Ame-010970	Astyanax mexicanus	66.20	0.00e+00	1698.00
IUUC-Bta-012905	Bos taurus	68.40	0.00e+00	1380.00
IUUC-Cel-018257	Caenorhabditis elegans	45.01	7.00e-94	338.00
IUUC-Cja-018789	Callithrix jacchus	69.98	0.00e+00	1396.00
IUUC-Cfa-021004	Canis familiaris	68.14	0.00e+00	1379.00
IUUC-Cpo-021529	Cavia porcellus	69.82	0.00e+00	1334.00
IUUC-Csa-024035	Chlorocebus sabaeus	68.70	0.00e+00	1420.00
IUUC-Cho-025036	Choloepus hoffmanni	70.00	0.00e+00	629.00
IUUC-Cin-025451	Ciona intestinalis	41.95	8.00e-83	302.00
IUUC-Dre-028556	Danio rerio	64.73	0.00e+00	1690.00
IUUC-Dno-029240	Dasypus novemcinctus	67.32	0.00e+00	1281.00
IUUC-Dor-030495	Dipodomys ordii	68.69	0.00e+00	865.00
IUUC-Ete-032741	Echinops telfairi	69.27	0.00e+00	1363.00
IUUC-Eca-033661	Equus caballus	69.47	0.00e+00	1372.00
IUUC-Eeu-034648	Erinaceus europaeus	72.55	6.00e-167	582.00
IUUC-Fca-035646	Felis catus	68.05	0.00e+00	1377.00
IUUC-Fal-037094	Ficedula albicollis	71.30	0.00e+00	1443.00
IUUC-Gmo-038869	Gadus morhua	75.20	0.00e+00	1492.00
IUUC-Gga-041170	Gallus gallus	72.28	0.00e+00	1430.00
IUUC-Gac-041901	Gasterosteus aculeatus	81.88	0.00e+00	1672.00
IUUC-Ggo-044708	Gorilla gorilla	70.65	0.00e+00	1386.00
IUUC-Hsa-046791	Homo sapiens	70.75	0.00e+00	1386.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	69.57	0.00e+00	1310.00
IUUC-Lch-050456	Latimeria chalumnae	66.21	0.00e+00	1073.00
IUUC-Loc-052861	Lepisosteus oculatus	55.40	0.00e+00	1442.00
IUUC-Laf-053788	Loxodonta africana	70.15	0.00e+00	1359.00
IUUC-Mcc-055693	Macaca mulatta	68.52	0.00e+00	1412.00
IUUC-Meu-055921	Macropus eugenii	70.18	0.00e+00	1181.00
IUUC-Mga-059879	Meleagris gallopavo	71.84	0.00e+00	1419.00
IUUC-Mmr-060802	Microcebus murinus	68.94	0.00e+00	1370.00
IUUC-Mdo-061856	Monodelphis domestica	71.33	0.00e+00	1353.00
IUUC-Mmu-063874	Mus musculus	69.12	0.00e+00	1363.00
IUUC-Mpu-066166	Mustela putorius furo	67.99	0.00e+00	1375.00
IUUC-Nle-070161	Nomascus leucogenys	69.33	0.00e+00	1386.00
IUUC-Opr-071015	Ochotona princeps	69.51	0.00e+00	1333.00
IUUC-Ont-072308	Oreochromis niloticus	79.01	0.00e+00	2242.00
IUUC-Oan-072723	Ornithorhynchus anatinus	69.36	0.00e+00	1365.00
IUUC-Ocu-073938	Oryctolagus cuniculus	68.33	0.00e+00	1367.00
IUUC-Ola-086375	Oryzias latipes	79.00	0.00e+00	1800.00
IUUC-Oga-088297	Otolemur garnettii	68.78	0.00e+00	1361.00
IUUC-Oar-089675	Ovis aries	64.49	0.00e+00	1223.00
IUUC-Ptr-091621	Pan troglodytes	70.65	0.00e+00	1384.00
IUUC-Pan-092118	Papio anubis	68.70	0.00e+00	1420.00
IUUC-Pma-094154	Petromyzon marinus	50.00	2.00e-112	399.00
IUUC-Pfo-097246	Poecilia formosa	95.67	0.00e+00	2214.00
IUUC-Pab-098551	Pongo abelii	70.04	0.00e+00	1369.00
IUUC-Pca-100158	Procavia capensis	67.58	0.00e+00	1290.00
IUUC-Pva-103160	Pteropus vampyrus	70.03	0.00e+00	1334.00
IUUC-Rno-105355	Rattus norvegicus	68.31	0.00e+00	1338.00
IUUC-Sha-107057	Sarcophilus harrisii	69.29	0.00e+00	1410.00
IUUC-Sar-113011	Sorex araneus	65.18	0.00e+00	992.00
IUUC-Ssc-115761	Sus scrofa	68.14	0.00e+00	1379.00
IUUC-Tgu-116956	Taeniopygia guttata	60.94	0.00e+00	756.00
IUUC-Tru-118739	Takifugu rubripes	69.79	0.00e+00	1965.00
IUUC-Tsy-118827	Tarsius syrichta	76.50	0.00e+00	683.00
IUUC-Tni-119921	Tetraodon nigroviridis	82.28	0.00e+00	1650.00
IUUC-Tbe-128017	Tupaia belangeri	67.92	0.00e+00	1315.00
IUUC-Ttr-128869	Tursiops truncatus	69.09	0.00e+00	1339.00
IUUC-Vpa-130427	Vicugna pacos	64.46	7.00e-179	621.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence