iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074188

Ensembl Protein ID

ENSOCUP00000000775.3

UniProt Accession

G1SEA7; G1SEA7_RABIT

Genbank Protein ID

ENSOCUP00000000775

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AAGW02030526

Gene Name

PRKAA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000000897.3	ENSOCUT00000000897.3	ENSOCUP00000000775.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	50.56	1.00e-110	397.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	39.01	3.00e-94	340.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MATAEKQKHD GRVKIGHYIL GDTLGVGTFG KVKVGKHELT GHKVAVKILN RQKIRSLDVV 60
GKIRREIQNL KLFRHPHIIK LYQVISTPSD IFMVMEYVSG GELFDYICKN GRKSDVPGVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCGTGCGC AGACTCAGTG TCTGGAGGAA GATGGCGACA GCCGAGAAGC AGAAACACGA 60
CGGGCGGGTG AAGATCGGCC ACTACATCCT GGGGGACACG CTGGGGGTCG GCACCTTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0061762--P:CAMKK-AMPK signaling cascade
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0019395--P:fatty acid oxidation
GO:0042593--P:glucose homeostasis
GO:0006006--P:glucose metabolic process
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0050995--P:negative regulation of lipid catabolic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0010628--P:positive regulation of gene expression
GO:0048643--P:positive regulation of skeletal muscle tissue development
GO:0042752--P:regulation of circadian rhythm
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:1901563--P:response to camptothecin
GO:0010332--P:response to gamma radiation
GO:0042542--P:response to hydrogen peroxide
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	45.64	3.00e-117	415.00
IUUC-Aml-001907	Ailuropoda melanoleuca	96.45	0.00e+00	1027.00
IUUC-Atr-002770	Amborella trichopoda	46.93	2.00e-121	429.00
IUUC-Apl-003395	Anas platyrhynchos	72.30	0.00e+00	795.00
IUUC-Aca-004480	Anolis carolinensis	75.00	0.00e+00	815.00
IUUC-Aly-006289	Arabidopsis lyrata	50.79	1.00e-120	426.00
IUUC-Ath-007014	Arabidopsis thaliana	51.01	6.00e-121	427.00
IUUC-Ago-007957	Ashbya gossypii	40.88	3.00e-111	395.00
IUUC-Acl-008103	Aspergillus clavatus	57.19	1.00e-97	351.00
IUUC-Afl-008555	Aspergillus flavus	56.51	4.00e-98	352.00
IUUC-Afu-008949	Aspergillus fumigatus	56.85	1.00e-97	350.00
IUUC-Ani-009408	Aspergillus nidulans	57.44	5.00e-98	351.00
IUUC-Ang-009551	Aspergillus niger	56.51	3.00e-97	349.00
IUUC-Aor-010176	Aspergillus oryzae	56.51	5.00e-98	352.00
IUUC-Ate-010287	Aspergillus terreus	58.51	2.00e-97	350.00
IUUC-Ame-011019	Astyanax mexicanus	72.60	0.00e+00	834.00
IUUC-Bgr-012045	Blumeria graminis	55.82	3.00e-97	349.00
IUUC-Bta-012786	Bos taurus	96.45	0.00e+00	1032.00
IUUC-Bci-013774	Botrytis cinerea	54.43	3.00e-98	353.00
IUUC-Bdi-014319	Brachypodium distachyon	45.80	1.00e-118	420.00
IUUC-Bol-016242	Brassica oleracea	46.77	9.00e-124	436.00
IUUC-Bra-016750	Brassica rapa	47.59	5.00e-124	437.00
IUUC-Cel-018518	Caenorhabditis elegans	56.90	6.00e-178	617.00
IUUC-Cja-019386	Callithrix jacchus	73.59	0.00e+00	851.00
IUUC-Cfa-020177	Canis familiaris	96.24	0.00e+00	991.00
IUUC-Cpo-021805	Cavia porcellus	73.42	0.00e+00	847.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	52.84	2.00e-93	335.00
IUUC-Csa-024267	Chlorocebus sabaeus	73.94	0.00e+00	846.00
IUUC-Cho-024859	Choloepus hoffmanni	98.87	0.00e+00	1017.00
IUUC-Cin-025550	Ciona intestinalis	58.39	0.00e+00	650.00
IUUC-Csv-026139	Ciona savignyi	56.86	0.00e+00	655.00
IUUC-Cne-027044	Cryptococcus neoformans	45.36	2.00e-103	369.00
IUUC-Cme-027289	Cyanidioschyzon merolae	44.92	1.00e-107	383.00
IUUC-Dre-027749	Danio rerio	81.12	0.00e+00	936.00
IUUC-Dno-030006	Dasypus novemcinctus	96.45	0.00e+00	1023.00
IUUC-Dor-030578	Dipodomys ordii	73.24	0.00e+00	847.00
IUUC-Dse-031507	Dothistroma septosporum	59.22	8.00e-102	364.00
IUUC-Dme-031704	Drosophila melanogaster	55.96	2.00e-175	608.00
IUUC-Ete-033055	Echinops telfairi	97.53	0.00e+00	1079.00
IUUC-Eca-034239	Equus caballus	96.23	0.00e+00	988.00
IUUC-Fca-035754	Felis catus	98.23	0.00e+00	1050.00
IUUC-Fal-037363	Ficedula albicollis	91.68	0.00e+00	988.00
IUUC-Fox-038073	Fusarium oxysporum	55.85	4.00e-99	355.00
IUUC-Fso-038236	Fusarium solani	55.18	2.00e-95	343.00
IUUC-Gmo-039633	Gadus morhua	79.97	0.00e+00	960.00
IUUC-Ggr-039987	Gaeumannomyces graminis	48.28	6.00e-99	355.00
IUUC-Gga-040546	Gallus gallus	73.77	0.00e+00	846.00
IUUC-Gac-041822	Gasterosteus aculeatus	71.63	0.00e+00	802.00
IUUC-Gma-042712	Glycine max	46.29	5.00e-121	427.00
IUUC-Ggo-044797	Gorilla gorilla	96.45	0.00e+00	1024.00
IUUC-Hsa-045867	Homo sapiens	96.63	0.00e+00	1025.00
IUUC-Hvu-047406	Hordeum vulgare	45.78	1.00e-119	423.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	73.59	0.00e+00	851.00
IUUC-Kpa-049190	Komagataella pastoris	42.23	9.00e-114	404.00
IUUC-Lch-049623	Latimeria chalumnae	87.61	0.00e+00	940.00
IUUC-Lpe-051392	Leersia perrieri	50.34	1.00e-121	430.00
IUUC-Loc-052362	Lepisosteus oculatus	87.40	0.00e+00	921.00
IUUC-Lma-053054	Leptosphaeria maculans	55.88	2.00e-102	366.00
IUUC-Laf-053799	Loxodonta africana	96.28	0.00e+00	1057.00
IUUC-Mcc-055862	Macaca mulatta	73.59	0.00e+00	852.00
IUUC-Mor-057170	Magnaporthe oryzae	55.56	3.00e-98	352.00
IUUC-Mpo-057302	Magnaporthe poae	47.57	4.00e-99	355.00
IUUC-Mtr-058309	Medicago truncatula	47.06	9.00e-122	430.00
IUUC-Mla-059058	Melampsora laricipopulina	40.07	2.00e-101	363.00
IUUC-Mga-059206	Meleagris gallopavo	72.63	0.00e+00	787.00
IUUC-Mvi-060337	Microbotryum violaceum	48.66	8.00e-98	351.00
IUUC-Mmr-061761	Microcebus murinus	96.81	0.00e+00	1027.00
IUUC-Mdo-062160	Monodelphis domestica	73.42	0.00e+00	845.00
IUUC-Mmu-063406	Mus musculus	73.54	0.00e+00	842.00
IUUC-Mac-064518	Musa acuminata	47.49	1.00e-115	410.00
IUUC-Mpu-066326	Mustela putorius furo	72.49	0.00e+00	790.00
IUUC-Mlu-068227	Myotis lucifugus	94.92	0.00e+00	980.00
IUUC-Nfi-068493	Neosartorya fischeri	56.85	8.00e-98	351.00
IUUC-Ncr-068665	Neurospora crassa	56.38	3.00e-100	359.00
IUUC-Nle-070158	Nomascus leucogenys	73.59	0.00e+00	853.00
IUUC-Opr-070272	Ochotona princeps	98.05	0.00e+00	1050.00
IUUC-Ont-072027	Oreochromis niloticus	81.66	0.00e+00	937.00
IUUC-Oan-073322	Ornithorhynchus anatinus	89.36	0.00e+00	981.00
IUUC-Oba-075436	Oryza barthii	46.68	1.00e-122	433.00
IUUC-Obr-076507	Oryza brachyantha	46.61	6.00e-123	434.00
IUUC-Ogl-077718	Oryza glaberrima	50.34	8.00e-120	423.00
IUUC-Ogu-078349	Oryza glumaepatula	46.09	1.00e-122	433.00
IUUC-Oin-079889	Oryza indica	45.63	2.00e-120	425.00
IUUC-Olo-080521	Oryza longistaminata	46.68	1.00e-122	433.00
IUUC-Ome-081630	Oryza meridionalis	46.48	3.00e-122	431.00
IUUC-Oni-082211	Oryza nivara	46.68	7.00e-123	434.00
IUUC-Opu-083617	Oryza punctata	45.97	1.00e-121	430.00
IUUC-Oru-084252	Oryza rufipogon	46.68	8.00e-123	433.00
IUUC-Osa-085548	Oryza sativa	46.68	8.00e-123	433.00
IUUC-Ola-086366	Oryzias latipes	81.69	0.00e+00	948.00
IUUC-Olu-087861	Ostreococcus lucimarinus	47.02	3.00e-114	405.00
IUUC-Oga-088003	Otolemur garnettii	96.81	0.00e+00	1026.00
IUUC-Oar-089933	Ovis aries	96.45	0.00e+00	1032.00
IUUC-Ptr-090718	Pan troglodytes	96.63	0.00e+00	1025.00
IUUC-Pan-092526	Papio anubis	96.45	0.00e+00	1023.00
IUUC-Psi-094034	Pelodiscus sinensis	90.81	0.00e+00	977.00
IUUC-Pno-095030	Phaeosphaeria nodorum	55.08	2.00e-100	359.00
IUUC-Ppa-095615	Physcomitrella patens	49.45	6.00e-120	424.00
IUUC-Pfo-097050	Poecilia formosa	81.35	0.00e+00	934.00
IUUC-Pab-098519	Pongo abelii	96.63	0.00e+00	1025.00
IUUC-Pop-099781	Populus trichocarpa	52.05	7.00e-123	434.00
IUUC-Pca-101104	Procavia capensis	98.28	0.00e+00	771.00
IUUC-Ppe-101642	Prunus persica	47.85	4.00e-120	424.00
IUUC-Pva-102470	Pteropus vampyrus	73.42	0.00e+00	846.00
IUUC-Pgr-103406	Puccinia graminis	57.91	9.00e-88	317.00
IUUC-Ptt-103713	Puccinia triticina	47.67	2.00e-69	256.00
IUUC-Pte-104259	Pyrenophora teres	53.73	2.00e-100	360.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	48.13	2.00e-101	363.00
IUUC-Rno-104960	Rattus norvegicus	73.06	0.00e+00	848.00
IUUC-Sce-106290	Saccharomyces cerevisiae	40.22	2.00e-108	386.00
IUUC-Sha-107603	Sarcophilus harrisii	94.86	0.00e+00	1013.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	51.40	3.00e-106	379.00
IUUC-Spo-108202	Schizosaccharomyces pombe	39.39	2.00e-103	369.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	54.75	7.00e-98	351.00
IUUC-Smo-109309	Selaginella moellendorffii	44.79	6.00e-119	421.00
IUUC-Sit-109745	Setaria italica	51.25	7.00e-124	437.00
IUUC-Sly-110890	Solanum lycopersicum	51.47	1.00e-122	433.00
IUUC-Stu-112144	Solanum tuberosum	44.67	2.00e-113	402.00
IUUC-Sar-113521	Sorex araneus	98.63	0.00e+00	833.00
IUUC-Sbi-114764	Sorghum bicolor	46.81	7.00e-125	440.00
IUUC-Sre-115141	Sporisorium reilianum	63.29	1.00e-110	394.00
IUUC-Ssc-115732	Sus scrofa	96.42	0.00e+00	990.00
IUUC-Tgu-117190	Taeniopygia guttata	91.15	0.00e+00	981.00
IUUC-Tru-118735	Takifugu rubripes	71.73	0.00e+00	824.00
IUUC-Tsy-119503	Tarsius syrichta	69.83	0.00e+00	745.00
IUUC-Tni-119833	Tetraodon nigroviridis	81.69	0.00e+00	929.00
IUUC-Tca-121386	Theobroma cacao	46.31	5.00e-122	431.00
IUUC-Tre-122070	Trichoderma reesei	47.19	9.00e-100	357.00
IUUC-Tvi-122305	Trichoderma virens	52.00	3.00e-99	356.00
IUUC-Tae-123515	Triticum aestivum	45.98	1.00e-121	429.00
IUUC-Tur-126416	Triticum urartu	45.49	1.00e-118	420.00
IUUC-Tme-127174	Tuber melanosporum	38.15	3.00e-66	245.00
IUUC-Tbe-127791	Tupaia belangeri	73.36	3.00e-100	358.00
IUUC-Ttr-129224	Tursiops truncatus	96.99	0.00e+00	1056.00
IUUC-Uma-129372	Ustilago maydis	62.94	1.00e-109	390.00
IUUC-Vda-129819	Verticillium dahliae	50.84	3.00e-84	306.00
IUUC-Vpa-130220	Vicugna pacos	72.07	0.00e+00	781.00
IUUC-Vvi-131649	Vitis vinifera	47.22	3.00e-123	435.00
IUUC-Xtr-132954	Xenopus tropicalis	73.99	0.00e+00	850.00
IUUC-Xma-134082	Xiphophorus maculatus	81.43	0.00e+00	860.00
IUUC-Yli-134422	Yarrowia lipolytica	41.96	2.00e-112	399.00
IUUC-Zma-135621	Zea mays	52.59	5.00e-117	414.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence