iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020524

Ensembl Protein ID

ENSCAFP00000035942.1

UniProt Accession

J9JHL1; J9JHL1_CANLF

Genbank Protein ID

ENSCAFP00000035942

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013198

Gene Name

UBE2E2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004924.3	ENSCAFT00000007919.3	ENSCAFP00000035942.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	7.10e-48	162.2	76	211

Active Site

Position(s)	Description	Evidence
156	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel+e++ dpp+++sa+p+ + +++ew+ +ilGp++++Yeg++F l+i+f++dYPfkPPkv+f t+i+h+n++++  +Cl+ilk  
   Q: 76   RIQKELAEITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGEAFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQDVICLDILK-- 161
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 162  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYITNRAEHDQMARQ 211
           **********************************************9985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

GGRTGTAAGG GSSAEGSNMS TEAQRVDDSP STSGGSSDGD QRESVQQEPE REQVQPKKKE 60
GKISSKTAAK LTSAKRIQKE LAEITLDPPP NCSAGPKGDN IYEWRSTILG PPGSVYEGEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGCAGAA CTGGAACAGC CGCGGGTGGA GGCAGCAGCG CTGAGGGATC TAACATGTCC 60
ACTGAGGCAC AAAGAGTTGA TGACAGTCCA AGCACTAGTG GAGGAAGTTC TGATGGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0032020--P:ISG15-protein conjugation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005044	Anolis carolinensis	92.54	8.00e-93	332.00
IUUC-Cho-024986	Choloepus hoffmanni	84.08	7.00e-82	296.00
IUUC-Dre-027449	Danio rerio	84.58	1.00e-84	305.00
IUUC-Eeu-034931	Erinaceus europaeus	90.55	1.00e-88	318.00
IUUC-Gmo-039645	Gadus morhua	86.21	3.00e-87	313.00
IUUC-Gac-041661	Gasterosteus aculeatus	86.57	8.00e-87	312.00
IUUC-Loc-052673	Lepisosteus oculatus	89.05	2.00e-89	321.00
IUUC-Meu-056612	Macropus eugenii	88.89	3.00e-77	280.00
IUUC-Mmu-063733	Mus musculus	94.03	2.00e-94	338.00
IUUC-Ont-071325	Oreochromis niloticus	87.06	1.00e-87	315.00
IUUC-Pfo-097071	Poecilia formosa	82.04	4.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence