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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031803
Ensembl Protein ID FBpp0310217
UniProt Accession Q9VKK2; B5RIT6; Q7KTE5; Q8T9F8; WDR59_DROME
Genbank Protein ID AAS64677.1; AAL39932.1; AAZ66312.1; ACH92275.1
Protein Name WD repeat-containing protein 59 homolog
Genbank Nucleotide ID AE014134; AY069787; BT023805; BT044210
Gene Name CG4705
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0032339 FBtr0343622 FBpp0310217
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDPINA
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMUniProt
PHOSIDA
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.70e-20 71.2 127 164
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt  vt++++   d +llvs+s D   ++WDlr+ ++
   Q: 127  GHTRTVTDIDWhgKDpNLLVSCSIDTFSHIWDLREPRK 164
           8************777*****************98776 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Required for the regulation of the TORC1 pathway by amino acids.
 Required for the regulation of the TORC1 pathway by amino acids.
Protein Sequence
(Fasta)
MPPTETLRPG ERGTAGGPGA GAPEQTYIVR QSNKYYEHRD SQATAMSVDY SGQWVLLAGR 60
GHLALQRLGQ DDGSLRRHER QSKYEVSVAE FAICPSRKEY CAIATSQHID IVRWGTAEPH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031803|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACGCCTGTTG TTATTGTCTA TCGTTCTTAT CAGTTCAGTT TCTTCGTTTA ATTTTTGTTT 60
GTTGCAAAAA TGGTTTAAAT TCGCAGTCTT TTGCTTTTTG AGCACTTATT AGAGTAGGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031803|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006575--RWD-domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0035859--C:Seh1-associated complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling
KEGG dme:Dmel_CG4705
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002149 Ailuropoda melanoleuca 33.77 2.00e-149 522.00
IUUC-Apl-004021 Anas platyrhynchos 32.69 3.00e-140 491.00
IUUC-Aca-004977 Anolis carolinensis 33.67 2.00e-149 523.00
IUUC-Ago-007961 Ashbya gossypii 28.18 2.00e-45 176.00
IUUC-Acl-008161 Aspergillus clavatus 28.04 3.00e-47 183.00
IUUC-Afl-008686 Aspergillus flavus 26.62 1.00e-47 185.00
IUUC-Afu-008932 Aspergillus fumigatus 28.04 3.00e-48 187.00
IUUC-Ani-009493 Aspergillus nidulans 27.22 6.00e-48 186.00
IUUC-Ang-009876 Aspergillus niger 33.33 3.00e-45 177.00
IUUC-Aor-009926 Aspergillus oryzae 26.62 1.00e-47 185.00
IUUC-Ate-010274 Aspergillus terreus 33.33 2.00e-44 174.00
IUUC-Ame-011297 Astyanax mexicanus 45.13 7.00e-78 285.00
IUUC-Bgr-012173 Blumeria graminis 30.09 4.00e-37 149.00
IUUC-Bta-013261 Bos taurus 33.77 2.00e-149 522.00
IUUC-Bci-013971 Botrytis cinerea 33.53 2.00e-42 167.00
IUUC-Cja-019167 Callithrix jacchus 34.07 1.00e-148 520.00
IUUC-Cfa-020287 Canis familiaris 34.01 9.00e-150 523.00
IUUC-Cpo-022510 Cavia porcellus 33.13 2.00e-136 479.00
IUUC-Csa-023474 Chlorocebus sabaeus 33.86 5.00e-151 527.00
IUUC-Cho-024634 Choloepus hoffmanni 36.64 1.00e-76 280.00
IUUC-Cin-025642 Ciona intestinalis 25.93 8.00e-85 307.00
IUUC-Csv-025848 Ciona savignyi 33.50 1.00e-33 135.00
IUUC-Cgl-026531 Colletotrichum gloeosporioides 34.69 7.00e-41 162.00
IUUC-Cne-027088 Cryptococcus neoformans 30.27 3.00e-37 150.00
IUUC-Dre-028753 Danio rerio 33.10 7.00e-139 487.00
IUUC-Dno-029733 Dasypus novemcinctus 34.04 3.00e-147 515.00
IUUC-Dor-030781 Dipodomys ordii 39.75 1.00e-66 247.00
IUUC-Ete-032622 Echinops telfairi 31.53 1.00e-113 403.00
IUUC-Eca-033344 Equus caballus 33.84 4.00e-147 514.00
IUUC-Eeu-034523 Erinaceus europaeus 31.21 3.00e-127 449.00
IUUC-Fca-035650 Felis catus 33.87 8.00e-149 520.00
IUUC-Fal-037404 Ficedula albicollis 33.23 9.00e-148 516.00
IUUC-Fox-037955 Fusarium oxysporum 32.34 4.00e-38 153.00
IUUC-Fso-038289 Fusarium solani 31.82 5.00e-39 156.00
IUUC-Gmo-038547 Gadus morhua 31.76 6.00e-138 484.00
IUUC-Ggr-039858 Gaeumannomyces graminis 34.19 1.00e-38 155.00
IUUC-Gga-041030 Gallus gallus 33.27 4.00e-150 524.00
IUUC-Gac-042581 Gasterosteus aculeatus 34.42 2.00e-117 416.00
IUUC-Ggo-044641 Gorilla gorilla 34.17 6.00e-151 527.00
IUUC-Hsa-046134 Homo sapiens 33.90 2.00e-150 526.00
IUUC-Itr-048551 Ictidomys tridecemlineatus 43.66 6.00e-82 296.00
IUUC-Kpa-049091 Komagataella pastoris 32.52 2.00e-40 160.00
IUUC-Lch-050288 Latimeria chalumnae 45.79 3.00e-84 305.00
IUUC-Loc-052802 Lepisosteus oculatus 32.02 1.00e-136 480.00
IUUC-Lma-053296 Leptosphaeria maculans 30.75 2.00e-33 138.00
IUUC-Laf-053997 Loxodonta africana 33.66 4.00e-151 528.00
IUUC-Mcc-055855 Macaca mulatta 33.90 2.00e-150 526.00
IUUC-Meu-056898 Macropus eugenii 31.18 2.00e-38 154.00
IUUC-Mor-056913 Magnaporthe oryzae 36.30 1.00e-40 162.00
IUUC-Mpo-057612 Magnaporthe poae 33.82 1.00e-39 157.00
IUUC-Mla-059097 Melampsora laricipopulina 35.83 3.00e-39 156.00
IUUC-Mga-059218 Meleagris gallopavo 33.16 4.00e-148 518.00
IUUC-Mvi-060251 Microbotryum violaceum 31.33 9.00e-42 165.00
IUUC-Mmr-061093 Microcebus murinus 32.76 1.00e-137 483.00
IUUC-Mdo-062757 Monodelphis domestica 33.10 2.00e-141 496.00
IUUC-Mmu-063839 Mus musculus 34.03 1.00e-153 536.00
IUUC-Mpu-065977 Mustela putorius furo 33.87 2.00e-149 522.00
IUUC-Mlu-067460 Myotis lucifugus 33.37 2.00e-147 516.00
IUUC-Nfi-068250 Neosartorya fischeri 28.57 1.00e-50 195.00
IUUC-Ncr-068710 Neurospora crassa 33.04 1.00e-40 162.00
IUUC-Nle-070011 Nomascus leucogenys 33.80 8.00e-149 520.00
IUUC-Opr-070731 Ochotona princeps 32.25 3.00e-132 465.00
IUUC-Ont-072165 Oreochromis niloticus 32.12 7.00e-137 480.00
IUUC-Oan-072887 Ornithorhynchus anatinus 33.40 3.00e-148 518.00
IUUC-Ocu-073926 Oryctolagus cuniculus 32.80 5.00e-127 448.00
IUUC-Ola-087111 Oryzias latipes 31.39 1.00e-129 456.00
IUUC-Oga-088850 Otolemur garnettii 34.27 2.00e-151 529.00
IUUC-Oar-090291 Ovis aries 33.84 3.00e-150 525.00
IUUC-Ptr-091044 Pan troglodytes 33.90 4.00e-148 518.00
IUUC-Pan-092374 Papio anubis 33.86 4.00e-151 528.00
IUUC-Psi-093170 Pelodiscus sinensis 27.63 5.00e-35 142.00
IUUC-Pma-094544 Petromyzon marinus 44.44 6.00e-83 300.00
IUUC-Pno-095068 Phaeosphaeria nodorum 30.36 3.00e-33 137.00
IUUC-Pfo-096480 Poecilia formosa 33.23 6.00e-139 487.00
IUUC-Pab-098134 Pongo abelii 33.30 1.00e-144 506.00
IUUC-Pca-100763 Procavia capensis 34.29 9.00e-53 201.00
IUUC-Pva-102544 Pteropus vampyrus 34.18 2.00e-151 529.00
IUUC-Pgr-103257 Puccinia graminis 30.51 2.00e-40 160.00
IUUC-Ptt-103942 Puccinia triticina 32.12 5.00e-38 152.00
IUUC-Pte-104065 Pyrenophora teres 32.22 6.00e-36 146.00
IUUC-Rno-105468 Rattus norvegicus 33.65 5.00e-131 461.00
IUUC-Sce-106356 Saccharomyces cerevisiae 26.93 3.00e-48 186.00
IUUC-Sha-106662 Sarcophilus harrisii 33.47 4.00e-145 508.00
IUUC-Sja-107973 Schizosaccharomyces japonicus 26.40 4.00e-54 206.00
IUUC-Spo-108265 Schizosaccharomyces pombe 35.00 3.00e-46 180.00
IUUC-Ssl-108662 Sclerotinia sclerotiorum 33.73 2.00e-42 167.00
IUUC-Sar-113525 Sorex araneus 30.78 6.00e-61 228.00
IUUC-Sre-115163 Sporisorium reilianum 37.60 2.00e-42 167.00
IUUC-Ssc-116234 Sus scrofa 44.97 7.00e-82 296.00
IUUC-Tgu-116525 Taeniopygia guttata 32.60 2.00e-140 493.00
IUUC-Tru-118432 Takifugu rubripes 32.64 2.00e-145 509.00
IUUC-Tsy-119306 Tarsius syrichta 30.57 2.00e-70 259.00
IUUC-Tni-120757 Tetraodon nigroviridis 32.67 1.00e-140 493.00
IUUC-Tre-122187 Trichoderma reesei 34.74 2.00e-43 171.00
IUUC-Tvi-122367 Trichoderma virens 34.74 1.00e-43 171.00
IUUC-Tme-126986 Tuber melanosporum 35.69 2.00e-48 187.00
IUUC-Tbe-127800 Tupaia belangeri 27.54 6.00e-77 281.00
IUUC-Ttr-129154 Tursiops truncatus 34.85 1.00e-89 323.00
IUUC-Uma-129366 Ustilago maydis 36.54 7.00e-41 162.00
IUUC-Vda-129827 Verticillium dahliae 34.07 8.00e-41 162.00
IUUC-Vpa-130493 Vicugna pacos 33.60 3.00e-143 501.00
IUUC-Xtr-131941 Xenopus tropicalis 34.73 8.00e-122 430.00
IUUC-Xma-133903 Xiphophorus maculatus 34.38 9.00e-117 414.00
Created Date 25-Jun-2017

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