iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000017109.1	ENSONIT00000021593.1	ENSONIP00000021574.1
ENSONIG00000017109.1	ENSONIT00000021594.1	ENSONIP00000021575.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.90e-51	171.7	1266	1317

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+++ydy+a+n +e+++ kG  + v+  ++ d +W+kg  e +g  GlfP n+v+
   Q: 1266 QVIAIYDYTAANAEEMSFSKGQLINVL--DKSDPDWWKG--ESNGVTGLFPTNYVQ 1317
           689************************..99********..9************97 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MNGGPSVWAI SPEERDKHDQ MFDSLSPTMG YVTGDQAKKL FLQSGLPPSV LADIWTLADM 60
NKDGKMDRLE FSVAMKLIKL KLTGTPLPSS LPIIMKQPPV RAPTMNNPTT PAYGIGSMMP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTCTTATC TGCCTCCCAT CCCATCGATT GTTCTCCTTC TCCATCTGTT TCACTTTTAT 60
TCCTCCCTTT CTCTCTCCTC CCACTCGCCG GACGTTAGCA GCGCCCCGCA GGCTCCAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR027029--Intersectin-2
IPR000048--IQ_motif_EF-hand-BS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50096--IQ
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	34.46	6.00e-12	67.40
IUUC-Ame-011377	Astyanax mexicanus	74.64	0.00e+00	1216.00
IUUC-Loc-052646	Lepisosteus oculatus	67.29	0.00e+00	1321.00
IUUC-Mtr-057705	Medicago truncatula	22.55	7.00e-14	73.20
IUUC-Ocu-073856	Oryctolagus cuniculus	59.96	0.00e+00	1068.00
IUUC-Ola-086482	Oryzias latipes	78.04	0.00e+00	1285.00
IUUC-Pfo-096733	Poecilia formosa	78.97	0.00e+00	1514.00
IUUC-Tru-117714	Takifugu rubripes	75.67	0.00e+00	1424.00
IUUC-Tni-119752	Tetraodon nigroviridis	75.48	0.00e+00	1429.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence