iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054308

Ensembl Protein ID

ENSLAFP00000017255.2

UniProt Accession

G3TPE8; G3TPE8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RHBDD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000022438.2	ENSLAFT00000021408.2	ENSLAFP00000017255.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.60e-06	25.9	329	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 7    leqlveMGFdreealqaLraannnleaAveyLldg 41
           l+ql+ MGF++e+a+ aL+a  + +e Av +L dg
   Q: 329  LQQLERMGFPTEQAVVALAA-TGRVEGAVSLLVDG 362
           9*******************.7*********9986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MHARGPPGPL SPALPLTSST LMLLMSGLWL VGAGPSLTLV PELLLEPWQV HRLLTYALGH 60
TALPGLLLSL LLLATLGWQQ ERHLGTLRFL HASALLALAA GLLAVLLGAL GVPSVAGGCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATGCCA GGGGCCCCCC TGGCCCACTG TCCCCGGCCC TGCCTCTCAC CTCTTCCACT 60
TTGATGCTGC TGATGAGTGG CCTGTGGCTG GTCGGGGCCG GCCCCAGCCT CACCCTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR022764--Peptidase_S54_rhomboid_dom
IPR015940--UBA
IPR009060--UBA-like

Pfam

PF01694--Rhomboid
PF00627--UBA

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0004252--F:serine-type endopeptidase activity
GO:0001889--P:liver development
GO:0000165--P:MAPK cascade
GO:0032815--P:negative regulation of natural killer cell activation
GO:0045732--P:positive regulation of protein catabolic process
GO:0002673--P:regulation of acute inflammatory response
GO:0050708--P:regulation of protein secretion
GO:0009410--P:response to xenobiotic stimulus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001619	Ailuropoda melanoleuca	83.14	9.00e-80	290.00
IUUC-Aca-004494	Anolis carolinensis	39.41	4.00e-24	105.00
IUUC-Ame-010805	Astyanax mexicanus	57.95	3.00e-21	95.50
IUUC-Bta-012844	Bos taurus	81.52	9.00e-71	260.00
IUUC-Cja-019853	Callithrix jacchus	81.41	2.00e-88	318.00
IUUC-Cfa-021026	Canis familiaris	83.14	3.00e-96	345.00
IUUC-Csa-023360	Chlorocebus sabaeus	82.12	6.00e-96	343.00
IUUC-Dre-027575	Danio rerio	60.92	9.00e-23	100.00
IUUC-Dno-029113	Dasypus novemcinctus	80.68	2.00e-74	272.00
IUUC-Dor-030646	Dipodomys ordii	76.95	1.00e-93	336.00
IUUC-Eca-034158	Equus caballus	82.49	1.00e-101	362.00
IUUC-Eeu-034983	Erinaceus europaeus	69.19	8.00e-62	229.00
IUUC-Fca-035531	Felis catus	83.04	4.00e-100	357.00
IUUC-Ggo-045015	Gorilla gorilla	81.61	2.00e-93	335.00
IUUC-Hsa-046646	Homo sapiens	81.87	1.00e-93	336.00
IUUC-Itr-048164	Ictidomys tridecemlineatus	75.13	2.00e-87	316.00
IUUC-Lch-049560	Latimeria chalumnae	35.29	8.00e-23	100.00
IUUC-Loc-052194	Lepisosteus oculatus	45.10	1.10e-02	33.90
IUUC-Mcc-055034	Macaca mulatta	71.51	3.00e-68	251.00
IUUC-Meu-056317	Macropus eugenii	54.03	3.00e-37	148.00
IUUC-Mmr-061591	Microcebus murinus	77.68	2.00e-65	242.00
IUUC-Mdo-062745	Monodelphis domestica	52.08	8.00e-44	171.00
IUUC-Mmu-063304	Mus musculus	73.44	5.00e-88	317.00
IUUC-Mac-065073	Musa acuminata	45.71	2.70e-01	30.40
IUUC-Mpu-066394	Mustela putorius furo	81.42	8.00e-92	330.00
IUUC-Mlu-067595	Myotis lucifugus	79.38	3.00e-96	345.00
IUUC-Nle-069211	Nomascus leucogenys	81.15	9.00e-97	346.00
IUUC-Opr-070249	Ochotona princeps	63.77	2.00e-61	228.00
IUUC-Oan-073402	Ornithorhynchus anatinus	58.42	1.00e-07	49.30
IUUC-Ocu-074418	Oryctolagus cuniculus	73.86	2.00e-79	289.00
IUUC-Oba-075087	Oryza barthii	26.92	1.50e+00	27.70
IUUC-Obr-076453	Oryza brachyantha	27.14	1.00e-01	32.00
IUUC-Ogl-077238	Oryza glaberrima	26.92	1.50e+00	28.10
IUUC-Ogu-078621	Oryza glumaepatula	26.92	1.80e+00	27.70
IUUC-Oni-082521	Oryza nivara	26.92	2.70e+00	27.70
IUUC-Opu-083378	Oryza punctata	28.85	5.20e-01	30.00
IUUC-Oru-084947	Oryza rufipogon	26.92	1.70e+00	27.70
IUUC-Ola-087450	Oryzias latipes	53.66	9.00e-20	89.70
IUUC-Oga-088214	Otolemur garnettii	79.83	3.00e-105	375.00
IUUC-Oar-089324	Ovis aries	78.73	4.00e-33	135.00
IUUC-Ptr-091322	Pan troglodytes	78.83	1.00e-73	269.00
IUUC-Pan-092490	Papio anubis	82.38	1.00e-102	366.00
IUUC-Pfo-097125	Poecilia formosa	53.49	7.00e-19	87.40
IUUC-Pab-097546	Pongo abelii	82.38	1.00e-29	123.00
IUUC-Pva-102615	Pteropus vampyrus	81.45	6.00e-103	367.00
IUUC-Rno-105844	Rattus norvegicus	74.07	3.00e-88	318.00
IUUC-Sha-107118	Sarcophilus harrisii	53.48	2.00e-30	125.00
IUUC-Ssc-115786	Sus scrofa	81.66	1.00e-99	356.00
IUUC-Ttr-128407	Tursiops truncatus	77.13	2.00e-88	319.00
IUUC-Xtr-131878	Xenopus tropicalis	34.05	1.00e-21	97.10
IUUC-Xma-133198	Xiphophorus maculatus	57.14	1.00e-19	90.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence