iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054094

UUCD1 version

UUC-LoA-01094

Ensembl Protein ID

ENSLAFP00000007188.4

UniProt Accession

G3T223; G3T223_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP9Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000008552.4	ENSLAFT00000026250.1	ENSLAFP00000020239.1
ENSLAFG00000008552.4	ENSLAFT00000027122.1	ENSLAFP00000023666.1
ENSLAFG00000008552.4	ENSLAFT00000008559.4	ENSLAFP00000007188.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-84	283.9	1557	1956

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l                 k         +                             
   Q: 1557 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAiegtgsdvdddmsgdeK---------Qdnesnvdprddvfgypqqfedkpalskte 1634
           6******************************88888877666654331.........033334456677777777777777777777 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l  s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1635 drKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1701
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d+Le+++k + leg+n+y+cekc+kk
   Q: 1702 ------KALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSLEQYVKGDLLEGANAYHCEKCNKK 1777
           ......67999******************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts......................peekqke..... 274
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                       +     e     
   Q: 1778 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegdnvnpesqliqqneqS-----Esetag 1859
           *****************************************************89999888888888887665543.....144555 PP
   S: 275  kkkYeLiavvvHsGslssGHYvayvknekgk......WllfdDskVtevkeeevleetg...........................s 328
           ++kY+L++v+vHsG++s+GHY++y+ +++g+      W++fdD  Vte+k+++ +e+++                           +
   Q: 1860 STKYRLVGVLVHSGQASGGHYYSYIIQRNGGdgernrWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqkrwW 1946
           ***************************5444555556*******************9999*************************** PP
   S: 329  taYvlfYkrr 338
           +aY+lfY+r+
   Q: 1947 NAYILFYERM 1956
           ********96 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDGPPQL 60
EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGCCA CGACTCGTGG CTCTCCAGTA GGAGGGAATG ACAACCAGGG CCAGGCTCCT 60
GATGGACAGT CTCAGCCTCC CCTCCAACAG AATCAGGTAG GATGTTGGAG ATACTGGTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0030426--C:growth cone
GO:0016020--C:membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0048675--P:axon extension
GO:0030509--P:BMP signaling pathway
GO:0001764--P:neuron migration
GO:0016579--P:protein deubiquitination
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	98.33	0.00e+00	5028.00
IUUC-Apl-003592	Anas platyrhynchos	94.28	0.00e+00	4852.00
IUUC-Aca-004939	Anolis carolinensis	93.89	0.00e+00	4808.00
IUUC-Ame-011772	Astyanax mexicanus	88.67	0.00e+00	4563.00
IUUC-Bta-012775	Bos taurus	97.94	0.00e+00	4984.00
IUUC-Cja-019464	Callithrix jacchus	97.59	0.00e+00	4901.00
IUUC-Cfa-020569	Canis familiaris	98.81	0.00e+00	3236.00
IUUC-Csa-023405	Chlorocebus sabaeus	97.94	0.00e+00	4962.00
IUUC-Cho-024524	Choloepus hoffmanni	94.16	0.00e+00	803.00
IUUC-Cin-025551	Ciona intestinalis	63.50	2.00e-142	498.00
IUUC-Csv-025956	Ciona savignyi	53.61	0.00e+00	2493.00
IUUC-Dre-028329	Danio rerio	88.70	0.00e+00	4589.00
IUUC-Dno-028936	Dasypus novemcinctus	98.17	0.00e+00	5023.00
IUUC-Dor-030352	Dipodomys ordii	93.97	0.00e+00	2247.00
IUUC-Dme-032160	Drosophila melanogaster	47.95	0.00e+00	2176.00
IUUC-Ete-032287	Echinops telfairi	97.33	0.00e+00	2785.00
IUUC-Eca-033352	Equus caballus	98.60	0.00e+00	5059.00
IUUC-Eeu-034907	Erinaceus europaeus	87.17	0.00e+00	1853.00
IUUC-Fca-035458	Felis catus	98.83	0.00e+00	5059.00
IUUC-Fal-036924	Ficedula albicollis	94.02	0.00e+00	4754.00
IUUC-Gmo-039578	Gadus morhua	89.63	0.00e+00	4484.00
IUUC-Gga-040978	Gallus gallus	94.36	0.00e+00	4856.00
IUUC-Gac-041970	Gasterosteus aculeatus	89.97	0.00e+00	4585.00
IUUC-Ggo-045575	Gorilla gorilla	98.91	0.00e+00	5033.00
IUUC-Hsa-046295	Homo sapiens	98.99	0.00e+00	5037.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	98.25	0.00e+00	5025.00
IUUC-Lch-050493	Latimeria chalumnae	91.93	0.00e+00	4655.00
IUUC-Loc-052667	Lepisosteus oculatus	90.49	0.00e+00	4710.00
IUUC-Mcc-054861	Macaca mulatta	96.81	0.00e+00	4944.00
IUUC-Meu-056849	Macropus eugenii	84.27	0.00e+00	1443.00
IUUC-Mga-060159	Meleagris gallopavo	94.17	0.00e+00	4849.00
IUUC-Mmr-060732	Microcebus murinus	97.90	0.00e+00	5022.00
IUUC-Mdo-062274	Monodelphis domestica	94.63	0.00e+00	4917.00
IUUC-Mmu-064056	Mus musculus	97.32	0.00e+00	4989.00
IUUC-Mpu-066669	Mustela putorius furo	98.37	0.00e+00	5033.00
IUUC-Mlu-067516	Myotis lucifugus	97.43	0.00e+00	4980.00
IUUC-Nle-069664	Nomascus leucogenys	98.74	0.00e+00	3671.00
IUUC-Opr-070185	Ochotona princeps	88.91	0.00e+00	806.00
IUUC-Ont-072119	Oreochromis niloticus	90.47	0.00e+00	4619.00
IUUC-Oan-073154	Ornithorhynchus anatinus	94.20	0.00e+00	4895.00
IUUC-Ocu-074485	Oryctolagus cuniculus	99.14	0.00e+00	5099.00
IUUC-Ola-086350	Oryzias latipes	89.62	0.00e+00	4515.00
IUUC-Oga-088328	Otolemur garnettii	98.56	0.00e+00	5105.00
IUUC-Oar-090098	Ovis aries	98.79	0.00e+00	5054.00
IUUC-Pan-091741	Papio anubis	98.93	0.00e+00	3806.00
IUUC-Psi-093040	Pelodiscus sinensis	94.13	0.00e+00	4836.00
IUUC-Pfo-096871	Poecilia formosa	89.43	0.00e+00	4581.00
IUUC-Pab-098374	Pongo abelii	97.98	0.00e+00	4959.00
IUUC-Pca-100801	Procavia capensis	89.99	0.00e+00	2439.00
IUUC-Pva-102992	Pteropus vampyrus	92.98	0.00e+00	2425.00
IUUC-Rno-105377	Rattus norvegicus	97.51	0.00e+00	4997.00
IUUC-Sha-106648	Sarcophilus harrisii	91.99	0.00e+00	4734.00
IUUC-Smo-108879	Selaginella moellendorffii	28.04	0.00e+00	808.00
IUUC-Sar-113729	Sorex araneus	95.29	0.00e+00	3181.00
IUUC-Ssc-116261	Sus scrofa	93.08	0.00e+00	4843.00
IUUC-Tgu-117126	Taeniopygia guttata	94.24	0.00e+00	4852.00
IUUC-Tru-117676	Takifugu rubripes	89.60	0.00e+00	4585.00
IUUC-Tsy-119209	Tarsius syrichta	86.69	0.00e+00	2677.00
IUUC-Tni-120207	Tetraodon nigroviridis	85.47	0.00e+00	2044.00
IUUC-Tbe-128033	Tupaia belangeri	97.76	0.00e+00	1046.00
IUUC-Ttr-128742	Tursiops truncatus	96.85	0.00e+00	4948.00
IUUC-Vpa-130581	Vicugna pacos	94.86	0.00e+00	4809.00
IUUC-Xtr-132145	Xenopus tropicalis	91.76	0.00e+00	4759.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence