iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000002469.2	ENSLACT00000002782.1	ENSLACP00000002760.1
ENSLACG00000002469.2	ENSLACT00000025049.1	ENSLACP00000023617.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.60e-85	285.7	1551	1949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip +r+ +l+                k         +                             
   Q: 1551 VGLKNAGATCYMNSVIQQLYMIPAIRNGILNidgtgsdvdddmsgdeK---------Qdnesnvdprddvfsyhhqyedkpalskte 1628
           6******************************99888877766654331.........033333456677787777777777777777 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l  s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1629 drKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1695
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d+Le+++k + leg+n+y+cekc+kk
   Q: 1696 ------KALGHSAMLSKVLGGSFADQKICQGCPHKYECEESFTTLNVDIRNHQ-----NLLDSLEQYVKGDLLEGANAYHCEKCNKK 1771
           ......678999*****************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.....................peekqkekkkYeL 280
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                      p+++q  ++kY+L
   Q: 1772 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegddvnsetqiiqneqPDNEQPGSTKYRL 1858
           *****************************************************9999999999999888888877777777****** PP
   S: 281  iavvvHsGslssGHYvayvkn......ekgkWllfdDskVtevkeeevleetg...........................staYvlf 334
           ++v+vHsG++s+GHY++y+ +      ek++W++fdD  Vte+k+++ +e+++                           ++aY+lf
   Q: 1859 VGVLVHSGQASGGHYYSYIIQrnggdgEKNRWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqkrwWNAYILF 1945
           *********************6666655666*******************9999********************************* PP
   S: 335  Ykrr 338
           Y+r+
   Q: 1946 YERM 1949
           **96 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MTATTRGSPV GGNDNQGQAP DGQSQPPLPQ NQTSSPDSSN ENSPVSPPDE QGQGDGPPQL 60
EEEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAAAACTA TACTGTAATG CCTTTTCAGT TTCTGCAGGC CATCCTTGTA GTTTTATTTT 60
TGTGCTTCCT TGCAGAGTCT TGAAAGTAGA CTGTAAAAAT TGTGTTTGAG GACCAGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	92.71	0.00e+00	4650.00
IUUC-Apl-003592	Anas platyrhynchos	94.90	0.00e+00	4730.00
IUUC-Aca-004939	Anolis carolinensis	94.27	0.00e+00	4685.00
IUUC-Afl-008381	Aspergillus flavus	25.69	5.00e-58	221.00
IUUC-Aor-009931	Aspergillus oryzae	25.83	5.00e-58	221.00
IUUC-Ame-011772	Astyanax mexicanus	90.33	0.00e+00	4568.00
IUUC-Bta-012775	Bos taurus	92.43	0.00e+00	4612.00
IUUC-Bci-013798	Botrytis cinerea	27.55	7.00e-52	200.00
IUUC-Cja-019464	Callithrix jacchus	92.12	0.00e+00	4543.00
IUUC-Cfa-020569	Canis familiaris	91.83	0.00e+00	3039.00
IUUC-Csa-023405	Chlorocebus sabaeus	92.59	0.00e+00	4605.00
IUUC-Cho-024524	Choloepus hoffmanni	91.06	0.00e+00	771.00
IUUC-Cin-025551	Ciona intestinalis	63.75	6.00e-142	497.00
IUUC-Csv-025956	Ciona savignyi	54.28	0.00e+00	2529.00
IUUC-Dre-028329	Danio rerio	90.87	0.00e+00	4628.00
IUUC-Dno-028936	Dasypus novemcinctus	92.63	0.00e+00	4650.00
IUUC-Dor-030352	Dipodomys ordii	86.79	0.00e+00	2085.00
IUUC-Dme-032160	Drosophila melanogaster	48.07	0.00e+00	2182.00
IUUC-Ete-032287	Echinops telfairi	88.91	0.00e+00	2576.00
IUUC-Eca-033352	Equus caballus	91.65	0.00e+00	4638.00
IUUC-Eeu-034907	Erinaceus europaeus	81.90	0.00e+00	1733.00
IUUC-Fca-035458	Felis catus	92.05	0.00e+00	4668.00
IUUC-Fal-036924	Ficedula albicollis	94.70	0.00e+00	4737.00
IUUC-Gmo-039578	Gadus morhua	91.66	0.00e+00	4505.00
IUUC-Ggr-040075	Gaeumannomyces graminis	26.42	8.00e-54	207.00
IUUC-Gga-040978	Gallus gallus	95.02	0.00e+00	4745.00
IUUC-Gac-041970	Gasterosteus aculeatus	92.87	0.00e+00	4622.00
IUUC-Ggo-045575	Gorilla gorilla	91.97	0.00e+00	4627.00
IUUC-Hsa-046295	Homo sapiens	92.01	0.00e+00	4627.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	92.75	0.00e+00	4657.00
IUUC-Loc-052667	Lepisosteus oculatus	92.18	0.00e+00	4696.00
IUUC-Laf-054094	Loxodonta africana	92.16	0.00e+00	4645.00
IUUC-Mcc-054861	Macaca mulatta	91.30	0.00e+00	4587.00
IUUC-Meu-056849	Macropus eugenii	80.30	0.00e+00	1291.00
IUUC-Mga-060159	Meleagris gallopavo	94.79	0.00e+00	4736.00
IUUC-Mmr-060732	Microcebus murinus	92.29	0.00e+00	4650.00
IUUC-Mdo-062274	Monodelphis domestica	94.78	0.00e+00	4781.00
IUUC-Mmu-064056	Mus musculus	91.96	0.00e+00	4619.00
IUUC-Mpu-066669	Mustela putorius furo	92.75	0.00e+00	4655.00
IUUC-Mlu-067516	Myotis lucifugus	92.48	0.00e+00	4637.00
IUUC-Nle-069664	Nomascus leucogenys	92.20	0.00e+00	3459.00
IUUC-Opr-070185	Ochotona princeps	83.10	0.00e+00	751.00
IUUC-Ont-072119	Oreochromis niloticus	91.94	0.00e+00	4588.00
IUUC-Oan-073154	Ornithorhynchus anatinus	94.35	0.00e+00	4756.00
IUUC-Ocu-074485	Oryctolagus cuniculus	92.13	0.00e+00	4684.00
IUUC-Ola-086350	Oryzias latipes	92.08	0.00e+00	4581.00
IUUC-Oga-088328	Otolemur garnettii	91.69	0.00e+00	4696.00
IUUC-Oar-090098	Ovis aries	91.93	0.00e+00	4641.00
IUUC-Pan-091741	Papio anubis	92.24	0.00e+00	3584.00
IUUC-Psi-093040	Pelodiscus sinensis	94.55	0.00e+00	4724.00
IUUC-Pfo-096871	Poecilia formosa	92.42	0.00e+00	4615.00
IUUC-Pab-098374	Pongo abelii	92.59	0.00e+00	4602.00
IUUC-Pca-100801	Procavia capensis	83.97	0.00e+00	2303.00
IUUC-Pva-102992	Pteropus vampyrus	86.25	0.00e+00	2279.00
IUUC-Rno-105377	Rattus norvegicus	92.04	0.00e+00	4627.00
IUUC-Sha-106648	Sarcophilus harrisii	92.04	0.00e+00	4603.00
IUUC-Smo-108879	Selaginella moellendorffii	28.42	0.00e+00	837.00
IUUC-Sar-113729	Sorex araneus	90.53	0.00e+00	2914.00
IUUC-Ssc-116261	Sus scrofa	88.26	0.00e+00	4532.00
IUUC-Tgu-117126	Taeniopygia guttata	94.70	0.00e+00	4734.00
IUUC-Tru-117676	Takifugu rubripes	92.51	0.00e+00	4600.00
IUUC-Tsy-119209	Tarsius syrichta	80.91	0.00e+00	2523.00
IUUC-Tni-120207	Tetraodon nigroviridis	90.63	0.00e+00	2060.00
IUUC-Tbe-128033	Tupaia belangeri	85.89	0.00e+00	953.00
IUUC-Ttr-128742	Tursiops truncatus	90.96	0.00e+00	4578.00
IUUC-Vpa-130581	Vicugna pacos	88.97	0.00e+00	4448.00
IUUC-Xtr-132145	Xenopus tropicalis	93.83	0.00e+00	4724.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence