iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133294

Ensembl Protein ID

ENSXMAP00000018119.1

UniProt Accession

M4AUH4; M4AUH4_XIPMA

Genbank Protein ID

ENSXMAP00000018119

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01040346

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000018028.1	ENSXMAT00000018146.1	ENSXMAP00000018119.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-82	278.1	1558	1956

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l                 k         +                             
   Q: 1558 VGLKNAGATCYMNSVIQQLYMIPPIRNGILAiegtgtdvdddmsgdeK---------Qenesnvdprdevfsyhhqfddkpssksed 1635
           6******************************99888887777765431.........022233445677777777777777777766 PP
   S: 43   .kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsd 128
            ke +  +l++lq +f +l  s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                     
   Q: 1636 rKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL--------------------- 1701
           677777************************************************************..................... PP
   S: 129  eaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkq 215
                k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d++e+++k + leg+n+y+cekc+kk+
   Q: 1702 -----KALGHPPMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSMEQYVKGDLLEGANAYHCEKCNKKV 1778
           .....679999*****************************************.....9***************************** PP
   S: 216  eaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts..............peekqke.............k 275
           +++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++               +     +             +
   Q: 1779 DTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegddvnpenQ-----ViqqnepseptppgS 1860
           ****************************************************777776666665440.....044556666778889 PP
   S: 276  kkYeLiavvvHsGslssGHYvayvkn......ekgkWllfdDskVtevkeeevleetg...........................st 329
            kY+L++v+vHsG++s+GHY++y+ +      ek++W++fdD  Vte+k+++ +e+++                           ++
   Q: 1861 SKYRLVGVLVHSGQASGGHYYSYIIQrnggdgEKNRWYKFDDGDVTECKMDDEEEMKNqcfggeymgevfdhmmkrmsyrrqkrwWN 1947
           **************************6666655666*************999999888999************************** PP
   S: 330  aYvlfYkrr 338
           aY+lfY+r+
   Q: 1948 AYILFYERM 1956
           *******96 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MTATTRGSPV GGNDSQGQGQ APDAQSQPPL PQNQTSSPNS SNENSPVSPP DEQGQGEGPP 60
QLEEEEPAFP HTDLAKLDDM INRPRWVVPV LPKGELEVLL EAAIDLSKKG LDVKCEACQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTATGCT CTTCCATTCA GCGGGTGTTG TGTTAAGCAG AGTTAGTCGG GGTTGTGATG 60
CGAACCAGCT CATAGACATT GCCGGAGTGT TGGAGTTCAC ACAGCAGTCT GGCCTGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	90.35	0.00e+00	4546.00
IUUC-Apl-003592	Anas platyrhynchos	92.20	0.00e+00	4620.00
IUUC-Aca-004939	Anolis carolinensis	92.08	0.00e+00	4595.00
IUUC-Ame-011772	Astyanax mexicanus	93.01	0.00e+00	4724.00
IUUC-Bta-012775	Bos taurus	89.95	0.00e+00	4504.00
IUUC-Cel-018352	Caenorhabditis elegans	26.09	6.00e-53	204.00
IUUC-Cja-019464	Callithrix jacchus	89.69	0.00e+00	4433.00
IUUC-Cfa-020569	Canis familiaris	90.44	0.00e+00	2962.00
IUUC-Csa-023405	Chlorocebus sabaeus	89.99	0.00e+00	4490.00
IUUC-Cho-024524	Choloepus hoffmanni	89.51	0.00e+00	760.00
IUUC-Cin-025551	Ciona intestinalis	63.75	1.00e-142	499.00
IUUC-Csv-025956	Ciona savignyi	54.03	0.00e+00	2526.00
IUUC-Dre-028329	Danio rerio	93.29	0.00e+00	4742.00
IUUC-Dno-028936	Dasypus novemcinctus	90.31	0.00e+00	4546.00
IUUC-Dor-030352	Dipodomys ordii	84.58	0.00e+00	2043.00
IUUC-Dme-032160	Drosophila melanogaster	48.05	0.00e+00	2199.00
IUUC-Ete-032287	Echinops telfairi	87.05	0.00e+00	2524.00
IUUC-Eca-033352	Equus caballus	90.06	0.00e+00	4553.00
IUUC-Eeu-034907	Erinaceus europaeus	80.07	0.00e+00	1694.00
IUUC-Fca-035458	Felis catus	90.25	0.00e+00	4568.00
IUUC-Fal-036924	Ficedula albicollis	92.09	0.00e+00	4598.00
IUUC-Gmo-039578	Gadus morhua	96.43	0.00e+00	4782.00
IUUC-Gga-040978	Gallus gallus	92.47	0.00e+00	4632.00
IUUC-Gac-041970	Gasterosteus aculeatus	97.87	0.00e+00	4918.00
IUUC-Ggo-045575	Gorilla gorilla	90.02	0.00e+00	4520.00
IUUC-Hsa-046295	Homo sapiens	90.06	0.00e+00	4522.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	90.07	0.00e+00	4537.00
IUUC-Lch-050493	Latimeria chalumnae	92.32	0.00e+00	4613.00
IUUC-Loc-052667	Lepisosteus oculatus	93.23	0.00e+00	4753.00
IUUC-Laf-054094	Loxodonta africana	90.33	0.00e+00	4543.00
IUUC-Mcc-054861	Macaca mulatta	88.94	0.00e+00	4470.00
IUUC-Meu-056849	Macropus eugenii	79.06	0.00e+00	1291.00
IUUC-Mga-060159	Meleagris gallopavo	92.25	0.00e+00	4625.00
IUUC-Mmr-060732	Microcebus murinus	90.05	0.00e+00	4541.00
IUUC-Mdo-062274	Monodelphis domestica	92.59	0.00e+00	4687.00
IUUC-Mmu-064056	Mus musculus	89.60	0.00e+00	4517.00
IUUC-Mpu-066669	Mustela putorius furo	90.39	0.00e+00	4551.00
IUUC-Mlu-067516	Myotis lucifugus	89.92	0.00e+00	4519.00
IUUC-Nle-069664	Nomascus leucogenys	90.71	0.00e+00	3382.00
IUUC-Opr-070185	Ochotona princeps	81.76	0.00e+00	747.00
IUUC-Ont-072119	Oreochromis niloticus	98.15	0.00e+00	4920.00
IUUC-Oan-073154	Ornithorhynchus anatinus	92.60	0.00e+00	4677.00
IUUC-Ocu-074485	Oryctolagus cuniculus	90.25	0.00e+00	4581.00
IUUC-Ola-086350	Oryzias latipes	96.99	0.00e+00	4851.00
IUUC-Oga-088328	Otolemur garnettii	90.06	0.00e+00	4600.00
IUUC-Oar-090098	Ovis aries	90.02	0.00e+00	4539.00
IUUC-Pan-091741	Papio anubis	90.49	0.00e+00	3522.00
IUUC-Psi-093040	Pelodiscus sinensis	92.25	0.00e+00	4622.00
IUUC-Pfo-096871	Poecilia formosa	99.64	0.00e+00	4986.00
IUUC-Pab-098374	Pongo abelii	89.99	0.00e+00	4487.00
IUUC-Pca-100801	Procavia capensis	83.05	0.00e+00	2251.00
IUUC-Pva-102992	Pteropus vampyrus	84.77	0.00e+00	2238.00
IUUC-Rno-105377	Rattus norvegicus	89.68	0.00e+00	4525.00
IUUC-Sha-106648	Sarcophilus harrisii	90.16	0.00e+00	4510.00
IUUC-Smo-108879	Selaginella moellendorffii	28.40	0.00e+00	827.00
IUUC-Sar-113729	Sorex araneus	88.96	0.00e+00	2860.00
IUUC-Ssc-116261	Sus scrofa	87.12	0.00e+00	4480.00
IUUC-Tgu-117126	Taeniopygia guttata	92.20	0.00e+00	4623.00
IUUC-Tru-117676	Takifugu rubripes	97.20	0.00e+00	4883.00
IUUC-Tsy-119209	Tarsius syrichta	79.63	0.00e+00	2453.00
IUUC-Tni-120207	Tetraodon nigroviridis	91.60	0.00e+00	2199.00
IUUC-Tbe-128033	Tupaia belangeri	86.15	0.00e+00	943.00
IUUC-Ttr-128742	Tursiops truncatus	88.85	0.00e+00	4469.00
IUUC-Vpa-130581	Vicugna pacos	87.08	0.00e+00	4344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence