iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009422

Ensembl Protein ID

CADANIAP00009249

UniProt Accession

C8VPK3; C8VPK3_EMENI

Genbank Protein ID

CBF87021.1

Protein Name

NEDD8 conjugating enzyme (UbcL), putative (AFU_orthologue AFUA_3G14430)

Genbank Nucleotide ID

BN001307

Gene Name

ANIA_10324

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00009249	CADANIAT00009249	CADANIAP00009249

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.00e-37	126.2	34	166

Active Site

Position(s)	Description	Evidence
112	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           R++++l+el+  ++ ++ a p+ + d+ ++ ++i+ p++ +Y+gg F +++ +++++P +PPkvk+++ki+hPn++ +G+vCl+il+  e+W+
   Q: 34   RVQRDLQELTLGSTMKM-AFPNPD-DILNFTLTIE-PDEGMYKGGSFIFTFAVNQNFPHDPPKVKCTQKIYHPNIDLEGNVCLNILR--EDWK 121
           89999999976666554.444444.8*********.**************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           p+l+++ v++++q l+ epn ++pln+eaae l++nr  +k++vr
   Q: 122  PVLNLNAVIVGMQFLFLEPNASDPLNKEAAEDLRQNRDLFKRNVR 166
           *******************************************98 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MLKIWSMKQQ QQQAENAEGA AGKKKKKVTA AQLRVQRDLQ ELTLGSTMKM AFPNPDDILN 60
FTLTIEPDEG MYKGGSFIFT FAVNQNFPHD PPKVKCTQKI YHPNIDLEGN VCLNILREDW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTGATTTC GGTCCTGGTG GCAGCACCTT CGTCGGTCAA TATTCACCAT GCTAAAAATC 60
TGGTCTATGG TATGCACTCT CCCCTTCTGC AACCTAGACT GGATGCCAGT CAACCCAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0019788--F:NEDD8 transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000196	Aegilops tauschii	58.78	2.00e-49	186.00
IUUC-Aml-002007	Ailuropoda melanoleuca	62.59	5.00e-55	204.00
IUUC-Atr-003170	Amborella trichopoda	56.21	3.00e-50	189.00
IUUC-Aca-005037	Anolis carolinensis	59.24	1.00e-58	217.00
IUUC-Aly-005638	Arabidopsis lyrata	56.86	3.00e-50	189.00
IUUC-Ath-006876	Arabidopsis thaliana	56.86	3.00e-50	189.00
IUUC-Ago-007910	Ashbya gossypii	46.67	5.00e-39	151.00
IUUC-Acl-008364	Aspergillus clavatus	91.30	6.00e-82	294.00
IUUC-Afl-008463	Aspergillus flavus	90.76	2.00e-81	293.00
IUUC-Afu-008803	Aspergillus fumigatus	91.85	1.00e-81	293.00
IUUC-Ang-009728	Aspergillus niger	88.32	3.00e-72	261.00
IUUC-Aor-009962	Aspergillus oryzae	90.76	2.00e-81	293.00
IUUC-Ate-010430	Aspergillus terreus	83.85	1.00e-75	273.00
IUUC-Ame-011382	Astyanax mexicanus	60.00	2.00e-59	219.00
IUUC-Bgr-012306	Blumeria graminis	73.91	8.00e-74	267.00
IUUC-Bta-012818	Bos taurus	59.24	3.00e-59	218.00
IUUC-Bci-013626	Botrytis cinerea	73.37	1.00e-70	257.00
IUUC-Bdi-014079	Brachypodium distachyon	58.17	1.00e-51	193.00
IUUC-Bol-015241	Brassica oleracea	56.86	2.00e-50	189.00
IUUC-Bra-017368	Brassica rapa	57.52	3.00e-50	189.00
IUUC-Cja-019213	Callithrix jacchus	57.67	4.00e-57	211.00
IUUC-Cfa-020242	Canis familiaris	58.60	1.00e-57	213.00
IUUC-Cpo-022405	Cavia porcellus	55.98	8.00e-54	201.00
IUUC-Cre-022865	Chlamydomonas reinhardtii	52.45	3.00e-43	166.00
IUUC-Csa-023269	Chlorocebus sabaeus	59.24	3.00e-59	218.00
IUUC-Cin-025333	Ciona intestinalis	60.78	4.00e-54	202.00
IUUC-Csv-025898	Ciona savignyi	60.96	3.00e-51	192.00
IUUC-Cgl-026477	Colletotrichum gloeosporioides	77.72	9.00e-75	270.00
IUUC-Cne-027097	Cryptococcus neoformans	60.11	8.00e-66	240.00
IUUC-Cme-027287	Cyanidioschyzon merolae	47.44	6.00e-21	92.00
IUUC-Dre-028514	Danio rerio	63.40	7.00e-59	218.00
IUUC-Dno-029678	Dasypus novemcinctus	62.59	4.00e-55	205.00
IUUC-Dor-030940	Dipodomys ordii	40.44	5.00e-24	102.00
IUUC-Dse-031265	Dothistroma septosporum	77.72	7.00e-77	277.00
IUUC-Dme-032076	Drosophila melanogaster	53.01	2.00e-54	202.00
IUUC-Ete-032350	Echinops telfairi	46.09	2.00e-26	108.00
IUUC-Eca-034075	Equus caballus	58.15	3.00e-58	215.00
IUUC-Fca-035654	Felis catus	62.59	5.00e-55	204.00
IUUC-Fal-037283	Ficedula albicollis	62.65	2.00e-28	114.00
IUUC-Fox-037877	Fusarium oxysporum	75.14	2.00e-74	269.00
IUUC-Fso-038428	Fusarium solani	77.84	1.00e-76	276.00
IUUC-Gmo-039402	Gadus morhua	59.46	1.00e-58	217.00
IUUC-Ggr-039731	Gaeumannomyces graminis	80.98	7.00e-76	274.00
IUUC-Gga-041122	Gallus gallus	57.80	3.00e-52	196.00
IUUC-Gac-041480	Gasterosteus aculeatus	38.24	6.00e-24	101.00
IUUC-Gma-043805	Glycine max	56.86	3.00e-50	189.00
IUUC-Ggo-044436	Gorilla gorilla	59.24	3.00e-59	218.00
IUUC-Hsa-046026	Homo sapiens	59.24	3.00e-59	218.00
IUUC-Hvu-047056	Hordeum vulgare	58.55	9.00e-51	191.00
IUUC-Itr-047889	Ictidomys tridecemlineatus	59.24	3.00e-59	218.00
IUUC-Kpa-049315	Komagataella pastoris	56.95	2.00e-48	182.00
IUUC-Lch-050360	Latimeria chalumnae	66.36	2.00e-42	163.00
IUUC-Lpe-050743	Leersia perrieri	57.14	2.00e-51	192.00
IUUC-Loc-052137	Lepisosteus oculatus	39.55	3.00e-23	99.40
IUUC-Lma-053001	Leptosphaeria maculans	80.43	6.00e-76	274.00
IUUC-Laf-053463	Loxodonta africana	62.59	2.00e-54	202.00
IUUC-Mcc-054966	Macaca mulatta	70.51	6.00e-33	130.00
IUUC-Meu-056085	Macropus eugenii	61.64	2.00e-53	198.00
IUUC-Mor-057250	Magnaporthe oryzae	80.43	2.00e-73	265.00
IUUC-Mpo-057481	Magnaporthe poae	81.52	8.00e-74	267.00
IUUC-Mtr-058251	Medicago truncatula	56.21	5.00e-49	185.00
IUUC-Mla-059119	Melampsora laricipopulina	67.93	1.00e-71	260.00
IUUC-Mga-059881	Meleagris gallopavo	64.15	1.00e-39	152.00
IUUC-Mvi-060449	Microbotryum violaceum	61.54	9.00e-62	227.00
IUUC-Mmr-061511	Microcebus murinus	70.51	4.00e-33	130.00
IUUC-Mdo-061993	Monodelphis domestica	40.44	5.00e-24	102.00
IUUC-Mmu-063962	Mus musculus	59.24	3.00e-59	218.00
IUUC-Mac-064967	Musa acuminata	58.17	1.00e-52	197.00
IUUC-Mpu-066423	Mustela putorius furo	41.18	1.00e-24	103.00
IUUC-Mlu-066955	Myotis lucifugus	61.59	2.00e-55	205.00
IUUC-Nfi-068300	Neosartorya fischeri	91.85	1.00e-81	293.00
IUUC-Ncr-068944	Neurospora crassa	77.30	3.00e-73	265.00
IUUC-Nle-069051	Nomascus leucogenys	62.59	5.00e-55	204.00
IUUC-Opr-070635	Ochotona princeps	62.33	2.00e-54	202.00
IUUC-Ont-072348	Oreochromis niloticus	60.00	7.00e-59	218.00
IUUC-Ocu-074905	Oryctolagus cuniculus	59.24	3.00e-59	218.00
IUUC-Oba-075825	Oryza barthii	57.89	2.00e-51	193.00
IUUC-Obr-076431	Oryza brachyantha	58.17	1.00e-51	194.00
IUUC-Ogl-077404	Oryza glaberrima	58.17	2.00e-51	192.00
IUUC-Ogu-078073	Oryza glumaepatula	57.89	2.00e-51	193.00
IUUC-Oin-080060	Oryza indica	58.17	2.00e-51	194.00
IUUC-Olo-080602	Oryza longistaminata	58.94	4.00e-51	193.00
IUUC-Ome-081870	Oryza meridionalis	58.17	1.00e-51	194.00
IUUC-Oni-082426	Oryza nivara	57.89	2.00e-51	193.00
IUUC-Opu-083942	Oryza punctata	59.86	5.00e-51	191.00
IUUC-Oru-085104	Oryza rufipogon	57.89	2.00e-51	193.00
IUUC-Osa-085857	Oryza sativa	58.17	1.00e-51	194.00
IUUC-Olu-087854	Ostreococcus lucimarinus	59.09	4.00e-52	195.00
IUUC-Oga-088580	Otolemur garnettii	59.24	3.00e-59	218.00
IUUC-Oar-089623	Ovis aries	58.78	4.00e-49	185.00
IUUC-Ptr-091020	Pan troglodytes	62.33	2.00e-54	202.00
IUUC-Pan-092119	Papio anubis	62.59	5.00e-55	204.00
IUUC-Psi-093494	Pelodiscus sinensis	62.59	2.00e-54	202.00
IUUC-Pno-094972	Phaeosphaeria nodorum	77.08	1.00e-73	266.00
IUUC-Ppa-095751	Physcomitrella patens	60.78	8.00e-56	207.00
IUUC-Pfo-097205	Poecilia formosa	62.58	3.00e-57	212.00
IUUC-Pab-098434	Pongo abelii	59.24	3.00e-59	218.00
IUUC-Pop-099789	Populus trichocarpa	56.86	3.00e-51	192.00
IUUC-Pca-100300	Procavia capensis	62.33	6.00e-54	201.00
IUUC-Ppe-101143	Prunus persica	57.52	2.00e-50	189.00
IUUC-Pva-102143	Pteropus vampyrus	59.24	3.00e-59	218.00
IUUC-Pgr-103675	Puccinia graminis	65.38	3.00e-69	253.00
IUUC-Ptt-103997	Puccinia triticina	69.23	6.00e-70	254.00
IUUC-Pte-104042	Pyrenophora teres	79.89	3.00e-75	272.00
IUUC-Pyt-104616	Pyrenophora triticirepentis	82.31	6.00e-72	260.00
IUUC-Rno-105107	Rattus norvegicus	59.24	3.00e-59	218.00
IUUC-Sce-106385	Saccharomyces cerevisiae	45.57	1.00e-37	147.00
IUUC-Sha-106899	Sarcophilus harrisii	61.90	1.00e-53	200.00
IUUC-Sja-107789	Schizosaccharomyces japonicus	52.46	1.00e-52	196.00
IUUC-Spo-108143	Schizosaccharomyces pombe	52.46	7.00e-54	201.00
IUUC-Ssl-108427	Sclerotinia sclerotiorum	71.74	3.00e-69	252.00
IUUC-Smo-109440	Selaginella moellendorffii	57.07	1.00e-55	206.00
IUUC-Sit-109702	Setaria italica	58.55	2.00e-51	192.00
IUUC-Sly-111650	Solanum lycopersicum	56.86	2.00e-51	193.00
IUUC-Stu-112381	Solanum tuberosum	60.13	6.00e-52	194.00
IUUC-Sar-113632	Sorex araneus	59.24	4.00e-59	218.00
IUUC-Sbi-114357	Sorghum bicolor	59.21	6.00e-52	194.00
IUUC-Sre-114912	Sporisorium reilianum	71.04	3.00e-71	258.00
IUUC-Ssc-115597	Sus scrofa	40.44	3.00e-24	102.00
IUUC-Tgu-117397	Taeniopygia guttata	39.71	6.00e-24	101.00
IUUC-Tru-118496	Takifugu rubripes	38.24	1.00e-23	100.00
IUUC-Tsy-119639	Tarsius syrichta	72.84	1.00e-36	143.00
IUUC-Tni-119674	Tetraodon nigroviridis	65.52	2.00e-46	176.00
IUUC-Tca-121359	Theobroma cacao	57.52	2.00e-50	190.00
IUUC-Tre-122115	Trichoderma reesei	76.22	2.00e-72	262.00
IUUC-Tvi-122656	Trichoderma virens	77.12	2.00e-71	259.00
IUUC-Tae-124489	Triticum aestivum	58.55	9.00e-51	191.00
IUUC-Tur-126125	Triticum urartu	58.55	1.00e-50	191.00
IUUC-Tme-126950	Tuber melanosporum	77.72	3.00e-71	259.00
IUUC-Tbe-127874	Tupaia belangeri	61.76	2.00e-33	133.00
IUUC-Ttr-128213	Tursiops truncatus	65.73	2.00e-55	206.00
IUUC-Uma-129329	Ustilago maydis	66.48	3.00e-70	255.00
IUUC-Vda-129754	Verticillium dahliae	80.00	6.00e-75	271.00
IUUC-Vvi-131337	Vitis vinifera	58.17	4.00e-51	191.00
IUUC-Xtr-132742	Xenopus tropicalis	59.24	7.00e-59	217.00
IUUC-Xma-133558	Xiphophorus maculatus	63.40	1.00e-58	217.00
IUUC-Yli-134467	Yarrowia lipolytica	68.85	5.00e-68	248.00
IUUC-Zma-135527	Zea mays	60.53	1.00e-52	197.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence