iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133438

Ensembl Protein ID

ENSXMAP00000019108.1

UniProt Accession

M4AXB3; M4AXB3_XIPMA

Genbank Protein ID

ENSXMAP00000019108

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01005433

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000019051.1	ENSXMAT00000019136.1	ENSXMAP00000019108.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-28	96.1	1601	1634
UBD/Beta-Prp	1.70e-41	142.3	1359	1603

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H+d+v++la+ ++ ++l+s+++ g +kvW++  +
   Q: 1601 HKDWVCALAYvPGrPMLLSACRGGMLKVWNVENF 1634
           ***********999****************9765 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle.tgqclee 131
           +  +gh+++v +v+  ++  +l tgs+Drt k w+l tg+ + tlkgh ++v+s++++ps+  + s s  ++i+vwd++ + +c+++
   Q: 1359 SVAEGHSKPVLCVDATDE--LLFTGSKDRTCKMWNLVTGQEIATLKGHPNNVVSVKYCPSSGLVFSVS-TSYIKVWDIRdSAKCIRT 1442
           5569***********999..9**************************************766666666.88*******834677877 PP
   S: 132  .....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...ke 194
                                t+++ +  +n ++++p g++l ++ + ++vr+Wdl++++   +l+g h +sv +l++ ++     +
   Q: 1443 ltssgqvvtgdacagtttrtiTFAQGECQINQIALNPLGSVLYAA-AGNIVRMWDLNRMQATGKLSG-HIGSVMCLTVGQSLlgkDQ 1527
           *********************9***************99555443.347*****************9.*********8887788899 PP
   S: 195  lvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           +++gs+d +vk++d+ +g+  +   +h+      d + ++++   ++ l sgs D+ i+ W l++++l++++ + ++ 
   Q: 1528 VITGSKDHYVKIFDVAEGTLGNVGPAHNfepphyDGIECLAVQ--GDVLFSGSRDNGIKKWELEQQELTQQIPNAHKD 1603
           *******************988888888888888*********..*************************99887765 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MASQSDCCVK VALRIRPQMA KEKIEGCHVC TLVTPGEPQV LLGKDKAFTY DFVFDIDSEQ 60
QHIYQTCVYK LIEGCFEGYN ATVFAYGQTG SGKTYTMGTG FDVNPSLQEQ GIIPRAVHHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGAGACA GCTCTAGATT TCCGACGGCC CATGAACGCG GCACCACCCC CCTCTCTCGT 60
GCACGGTGTG AGCGCTCATT CAGCTTTATC GCCCAGAGAA GCGCTGTGGT TGCAGAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	73.81	0.00e+00	1377.00
IUUC-Apl-003204	Anas platyrhynchos	74.01	0.00e+00	753.00
IUUC-Aca-004506	Anolis carolinensis	72.98	0.00e+00	1417.00
IUUC-Ame-011515	Astyanax mexicanus	80.92	0.00e+00	2555.00
IUUC-Bta-013185	Bos taurus	64.79	0.00e+00	692.00
IUUC-Cja-018844	Callithrix jacchus	74.45	0.00e+00	1429.00
IUUC-Cfa-021187	Canis familiaris	74.93	0.00e+00	1441.00
IUUC-Cpo-022444	Cavia porcellus	74.59	0.00e+00	1430.00
IUUC-Csa-023852	Chlorocebus sabaeus	74.47	0.00e+00	1431.00
IUUC-Csv-026158	Ciona savignyi	59.38	1.00e-178	621.00
IUUC-Dre-027839	Danio rerio	77.74	0.00e+00	2484.00
IUUC-Dno-030058	Dasypus novemcinctus	71.41	0.00e+00	1346.00
IUUC-Dor-030673	Dipodomys ordii	74.28	0.00e+00	1414.00
IUUC-Ete-032705	Echinops telfairi	65.94	0.00e+00	717.00
IUUC-Eca-033885	Equus caballus	73.63	0.00e+00	1386.00
IUUC-Eeu-035338	Erinaceus europaeus	56.10	0.00e+00	861.00
IUUC-Fca-035388	Felis catus	74.76	0.00e+00	1436.00
IUUC-Fal-037044	Ficedula albicollis	74.66	0.00e+00	1494.00
IUUC-Gmo-039034	Gadus morhua	75.37	0.00e+00	2313.00
IUUC-Gac-041328	Gasterosteus aculeatus	86.91	0.00e+00	2810.00
IUUC-Ggo-045392	Gorilla gorilla	73.95	0.00e+00	1420.00
IUUC-Hsa-046713	Homo sapiens	74.47	0.00e+00	1432.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	73.51	0.00e+00	1305.00
IUUC-Lch-049786	Latimeria chalumnae	72.64	0.00e+00	2300.00
IUUC-Loc-052703	Lepisosteus oculatus	79.65	0.00e+00	2561.00
IUUC-Laf-054193	Loxodonta africana	67.59	0.00e+00	1277.00
IUUC-Mcc-055484	Macaca mulatta	73.20	0.00e+00	1423.00
IUUC-Meu-056278	Macropus eugenii	70.68	0.00e+00	1016.00
IUUC-Mga-059816	Meleagris gallopavo	71.42	0.00e+00	1409.00
IUUC-Mmr-061071	Microcebus murinus	70.68	0.00e+00	1401.00
IUUC-Mdo-062845	Monodelphis domestica	74.93	0.00e+00	1437.00
IUUC-Mmu-063967	Mus musculus	74.21	0.00e+00	1400.00
IUUC-Mpu-066448	Mustela putorius furo	73.51	0.00e+00	1420.00
IUUC-Nle-070037	Nomascus leucogenys	74.28	0.00e+00	1443.00
IUUC-Opr-070325	Ochotona princeps	71.51	0.00e+00	1358.00
IUUC-Ont-071851	Oreochromis niloticus	90.36	0.00e+00	2909.00
IUUC-Oan-073615	Ornithorhynchus anatinus	75.05	0.00e+00	1431.00
IUUC-Ocu-073855	Oryctolagus cuniculus	74.33	0.00e+00	1420.00
IUUC-Ola-086703	Oryzias latipes	90.58	0.00e+00	2919.00
IUUC-Oga-088171	Otolemur garnettii	71.37	0.00e+00	1333.00
IUUC-Ptr-090535	Pan troglodytes	73.29	0.00e+00	1419.00
IUUC-Pan-091917	Papio anubis	73.28	0.00e+00	1226.00
IUUC-Psi-093752	Pelodiscus sinensis	67.37	0.00e+00	1214.00
IUUC-Pfo-096827	Poecilia formosa	91.33	0.00e+00	2873.00
IUUC-Pab-098441	Pongo abelii	74.57	0.00e+00	1434.00
IUUC-Pca-100781	Procavia capensis	79.65	0.00e+00	759.00
IUUC-Pva-103099	Pteropus vampyrus	69.90	0.00e+00	1034.00
IUUC-Rno-105872	Rattus norvegicus	74.11	0.00e+00	1423.00
IUUC-Sha-107097	Sarcophilus harrisii	73.67	0.00e+00	1362.00
IUUC-Ssc-115638	Sus scrofa	72.97	0.00e+00	1117.00
IUUC-Tru-118242	Takifugu rubripes	88.32	0.00e+00	2915.00
IUUC-Tni-119976	Tetraodon nigroviridis	91.48	0.00e+00	1149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence