iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125073

Ensembl Protein ID

TRIAE_CS42_7DL_TGACv1_604032_AA1992770.1

UniProt Accession

A0A1D6CRW4; A0A1D6CRW4_WHEAT

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_7DL_TGACv1_604032_AA1992770	TRIAE_CS42_7DL_TGACv1_604032_AA1992770.1	TRIAE_CS42_7DL_TGACv1_604032_AA1992770.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-39	133.2	312	343
UBD/Beta-Prp	2.60e-49	170.7	64	344

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDl 30
           H  +v+c+++  ++ + l+s sdDgt+k+W+l
   Q: 312  HDTDVNCVRWcpQNpRVLASVSDDGTVKLWEL 343
           7778*******8556889************97 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgs 71
           l+g h+s +++ ++spd++lla +s dgt+ +w+++ g++  + +l+gh +ev++v++s++g++ +t+s
   Q: 64   LEGVHESTVRSCAWSPDGKLLADASFDGTTAIWEYSGGDFelVDTLEGHVNEVKSVSWSQSGSMVATCS 132
           788999****9****************************999*************************** PP
   S: 72   eDrtikvw...dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgq...clee... 131
           +Dr++ +w   + ++ +cv +l+gh+++v  ++++p  d+lvs s d+tirvw  + +    c+++   
   Q: 133  RDRAAWIWeilPGNDHECVDVLEGHTEDVKMVQWHPFFDVLVSVSYDNTIRVWADDGDGkwpCVQTlte 201
           ********655556**********************99**************98765531225555988 PP
   S: 132  .tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.............ktgkllrtltgghtdsvysl 186
             +sgh+++v++++++++g+ +v++s+D t+++Wd              ++ + + tl+g+h + + s+
   Q: 202  aGNSGHSSTVWSISFNQKGDRMVTCSDDCTLKIWDAsidlsqpttgeghESWRHISTLSGYHGRTIFSV 270
           899********************************************99999***************** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgec........vrtlnghtdnvksvrfs.pnderlvsgssDgsi 246
            ++s+g  ++sg+ d  + l+  +++ +        +++ ++h++ v++vr + +n   l+s+s+Dg++
   Q: 271  HWSSEG-VIASGAGDDAICLFAEENSMVegpsyrliLKKEKAHDTDVNCVRWCpQNPRVLASVSDDGTV 338
           ****98.9****************777788888888*****************77778899******** PP
   S: 247  riWdlr 252
           ++W l+
   Q: 339  KLWELQ 344
           ***886 PP

Organism

Triticum aestivum

Functional Description
(View)

Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.

Protein Sequence
(Fasta)

MDGGTAELRE THRLVGHADR AWALAWNPNP GAGAGPVLAS CGADKTVRIW KRAPDGAWHC 60
SDVLEGVHES TVRSCAWSPD GKLLADASFD GTTAIWEYSG GDFELVDTLE GHVNEVKSVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCCGGAA CCCTAGGCAC AGCGATCGCC GGCGAGCAGG CCATGGATGG CGGCACGGCG 60
GAGCTGCGCG AGACCCACCG CCTGGTTGGC CACGCCGACC GCGCGTGGGC ACTCGCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	85.67	5.00e-176	612.00
IUUC-Mga-059370	Meleagris gallopavo	35.57	1.00e-43	170.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence