iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049892

Ensembl Protein ID

ENSLACP00000007324.1

UniProt Accession

H3ACF3; H3ACF3_LATCH

Genbank Protein ID

ENSLACP00000007324

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AFYH01024838

Gene Name

SRC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000006496.1	ENSLACT00000007384.1	ENSLACP00000007324.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-13	49.3	87	141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +L++kkG+ ++++  ++++++W+ + + ++gk G +P+n+v+ 
   Q: 87   TFVALYDYESRTATDLSFKKGERLQIV--NNTEGDWWLAHSLTSGKTGYIPSNYVAP 141
           6789***********************..8999*********************985 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGSSKSKPKE PGQRSRSLDG AILSGTDSTN HGASSSQQSQ TPNKNAAADT ANPSSRDIAE 60
GKLFGGVSTS DTTSPQHSGQ MTGGVTTFVA LYDYESRTAT DLSFKKGERL QIVNNTEGDW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTGGGATC TGACTCAGGC ATTCCCCCTT TAGACTCAAC AATGGGAGCT CTTGCTTCCA 60
AAACAAATCT TCAAATCTGA ACCTTGGGCT TGTATTCTCA AAGAGAAACT GCGCAGAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0048920--P:posterior lateral line neuromast primordium migration
GO:0043114--P:regulation of vascular permeability
GO:0001878--P:response to yeast

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000140	Aegilops tauschii	30.71	3.00e-22	100.00
IUUC-Aml-001713	Ailuropoda melanoleuca	85.77	0.00e+00	956.00
IUUC-Aca-004237	Anolis carolinensis	86.85	0.00e+00	967.00
IUUC-Aly-005712	Arabidopsis lyrata	32.20	1.00e-18	88.60
IUUC-Ame-011887	Astyanax mexicanus	79.23	0.00e+00	876.00
IUUC-Bta-012982	Bos taurus	86.16	0.00e+00	959.00
IUUC-Bdi-014324	Brachypodium distachyon	35.11	6.00e-24	106.00
IUUC-Cja-019995	Callithrix jacchus	85.53	0.00e+00	954.00
IUUC-Cfa-020060	Canis familiaris	86.90	0.00e+00	968.00
IUUC-Cpo-021557	Cavia porcellus	86.78	0.00e+00	956.00
IUUC-Csa-023711	Chlorocebus sabaeus	85.71	0.00e+00	955.00
IUUC-Dre-028491	Danio rerio	81.67	0.00e+00	877.00
IUUC-Dno-029651	Dasypus novemcinctus	83.24	0.00e+00	938.00
IUUC-Ete-033170	Echinops telfairi	91.48	0.00e+00	876.00
IUUC-Eca-033970	Equus caballus	83.18	0.00e+00	915.00
IUUC-Fca-036113	Felis catus	86.90	0.00e+00	968.00
IUUC-Fal-036785	Ficedula albicollis	87.55	0.00e+00	978.00
IUUC-Gga-040899	Gallus gallus	88.15	0.00e+00	981.00
IUUC-Gac-042332	Gasterosteus aculeatus	80.86	0.00e+00	891.00
IUUC-Gma-043938	Glycine max	31.03	1.00e-22	102.00
IUUC-Ggo-044829	Gorilla gorilla	72.71	0.00e+00	769.00
IUUC-Hsa-046192	Homo sapiens	85.71	0.00e+00	954.00
IUUC-Hvu-047855	Hordeum vulgare	31.10	2.00e-23	103.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	85.71	0.00e+00	957.00
IUUC-Lpe-051166	Leersia perrieri	34.25	5.00e-24	106.00
IUUC-Loc-052812	Lepisosteus oculatus	83.27	0.00e+00	904.00
IUUC-Laf-053977	Loxodonta africana	85.74	0.00e+00	957.00
IUUC-Mcc-055159	Macaca mulatta	84.02	0.00e+00	950.00
IUUC-Mtr-058733	Medicago truncatula	32.05	3.00e-23	103.00
IUUC-Mga-060135	Meleagris gallopavo	87.73	0.00e+00	979.00
IUUC-Mmr-061168	Microcebus murinus	83.99	0.00e+00	950.00
IUUC-Mdo-063030	Monodelphis domestica	85.64	0.00e+00	965.00
IUUC-Mmu-063893	Mus musculus	85.92	0.00e+00	958.00
IUUC-Mpu-066411	Mustela putorius furo	86.90	0.00e+00	968.00
IUUC-Mlu-068139	Myotis lucifugus	85.16	0.00e+00	949.00
IUUC-Nle-070178	Nomascus leucogenys	83.21	0.00e+00	904.00
IUUC-Ont-072130	Oreochromis niloticus	80.55	0.00e+00	920.00
IUUC-Ocu-074403	Oryctolagus cuniculus	85.92	0.00e+00	952.00
IUUC-Oba-075994	Oryza barthii	34.25	4.00e-22	99.80
IUUC-Ogl-077331	Oryza glaberrima	34.70	3.00e-24	107.00
IUUC-Ogu-078962	Oryza glumaepatula	35.16	1.00e-24	108.00
IUUC-Oin-079172	Oryza indica	35.16	1.00e-24	108.00
IUUC-Olo-080286	Oryza longistaminata	35.16	1.00e-24	108.00
IUUC-Ome-081400	Oryza meridionalis	35.16	8.00e-25	108.00
IUUC-Oni-082734	Oryza nivara	35.16	1.00e-24	108.00
IUUC-Oru-084741	Oryza rufipogon	35.16	9.00e-25	108.00
IUUC-Osa-085779	Oryza sativa	36.07	2.00e-24	107.00
IUUC-Ola-086953	Oryzias latipes	81.95	0.00e+00	889.00
IUUC-Oga-088493	Otolemur garnettii	85.35	0.00e+00	951.00
IUUC-Oar-090279	Ovis aries	85.95	0.00e+00	956.00
IUUC-Ptr-091050	Pan troglodytes	85.71	0.00e+00	954.00
IUUC-Pan-091862	Papio anubis	86.67	0.00e+00	961.00
IUUC-Psi-093071	Pelodiscus sinensis	87.59	0.00e+00	975.00
IUUC-Pfo-096578	Poecilia formosa	80.91	0.00e+00	925.00
IUUC-Pab-097902	Pongo abelii	83.84	0.00e+00	947.00
IUUC-Rno-105847	Rattus norvegicus	85.77	0.00e+00	958.00
IUUC-Sha-107539	Sarcophilus harrisii	87.96	0.00e+00	970.00
IUUC-Sly-111920	Solanum lycopersicum	31.95	4.00e-23	103.00
IUUC-Stu-112331	Solanum tuberosum	32.71	2.00e-24	107.00
IUUC-Sbi-114480	Sorghum bicolor	36.24	1.00e-24	108.00
IUUC-Ssc-115762	Sus scrofa	85.58	0.00e+00	954.00
IUUC-Tru-117849	Takifugu rubripes	81.62	0.00e+00	881.00
IUUC-Tni-120843	Tetraodon nigroviridis	81.28	0.00e+00	912.00
IUUC-Tae-123192	Triticum aestivum	31.10	9.00e-23	102.00
IUUC-Tur-126022	Triticum urartu	31.10	2.00e-22	101.00
IUUC-Ttr-128702	Tursiops truncatus	80.44	0.00e+00	878.00
IUUC-Vvi-131181	Vitis vinifera	33.59	1.00e-22	101.00
IUUC-Xtr-132291	Xenopus tropicalis	83.70	0.00e+00	907.00
IUUC-Xma-133134	Xiphophorus maculatus	80.55	0.00e+00	922.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence