iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133183

Ensembl Protein ID

ENSXMAP00000019370.1

UniProt Accession

M4AY25; M4AY25_XIPMA

Genbank Protein ID

ENSXMAP00000019370

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01004157

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000019321.1	ENSXMAT00000019398.1	ENSXMAP00000019370.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.10e-148	494.6	179	482
E3 adaptor/Cullin RING/DCX/DWD	4.30e-27	93.1	315	345

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 179  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGYVQIWDAAAGKK 267
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd+ il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss  P+++++
   Q: 268  LSVLEGHTARVGALAWNADQLSSGSRDRVILQRDIRAPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSVLPVQQYT 356
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 357  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCTDTGSQVCNLAWSKHTNELVSTHGYSQNQILVWKYPSLTQVAKLTG 445
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k ++
   Q: 446  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKMRS 482
           ********************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 315  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 345
           8**********98889**************9 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MMDQDYECRL LRQINIQNEN ASPIKAVGAV RSLTPTSSPL SSPSKHGDRF IPSRAGANWS 60
VNFHRINEIE KSHSQNRKTK DGTTDSNKVD GLAYSALLKN ELLGAGIEKV QDPQSEDRRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGCTCTTC CCGTGGTGCT TTGGAAACCC AAATTGAATG CTCGACTAAA GAATATATTT 60
GTATTCTATT AATTCCTGTT TTAAAGGCAT AAGAAAAGAC CTGAGTTTGA CACGCCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	57.22	7.00e-115	407.00
IUUC-Aml-002003	Ailuropoda melanoleuca	86.76	0.00e+00	852.00
IUUC-Atr-002753	Amborella trichopoda	57.68	6.00e-134	471.00
IUUC-Apl-003212	Anas platyrhynchos	91.33	0.00e+00	904.00
IUUC-Aly-005442	Arabidopsis lyrata	54.30	5.00e-139	487.00
IUUC-Ath-006938	Arabidopsis thaliana	57.63	1.00e-137	483.00
IUUC-Ago-007784	Ashbya gossypii	42.48	2.00e-96	346.00
IUUC-Acl-008269	Aspergillus clavatus	50.10	5.00e-132	464.00
IUUC-Afl-008432	Aspergillus flavus	50.00	2.00e-131	462.00
IUUC-Afu-008829	Aspergillus fumigatus	50.10	8.00e-132	464.00
IUUC-Ani-009471	Aspergillus nidulans	50.52	6.00e-131	461.00
IUUC-Ang-009711	Aspergillus niger	50.21	5.00e-129	454.00
IUUC-Aor-010118	Aspergillus oryzae	50.00	2.00e-131	462.00
IUUC-Ate-010534	Aspergillus terreus	50.21	6.00e-131	461.00
IUUC-Ame-011011	Astyanax mexicanus	91.57	0.00e+00	877.00
IUUC-Bgr-012013	Blumeria graminis	51.12	4.00e-130	458.00
IUUC-Bta-012586	Bos taurus	90.93	0.00e+00	897.00
IUUC-Bci-013807	Botrytis cinerea	51.13	7.00e-125	441.00
IUUC-Bdi-014981	Brachypodium distachyon	71.15	1.00e-129	456.00
IUUC-Bol-016301	Brassica oleracea	53.78	1.00e-137	482.00
IUUC-Bra-017453	Brassica rapa	53.78	1.00e-137	482.00
IUUC-Cel-018472	Caenorhabditis elegans	65.18	3.00e-144	505.00
IUUC-Cja-019929	Callithrix jacchus	90.58	0.00e+00	893.00
IUUC-Cfa-020977	Canis familiaris	90.18	0.00e+00	889.00
IUUC-Cpo-021537	Cavia porcellus	91.53	0.00e+00	900.00
IUUC-Csa-023389	Chlorocebus sabaeus	90.93	0.00e+00	898.00
IUUC-Cin-025327	Ciona intestinalis	68.85	1.00e-180	625.00
IUUC-Csv-025921	Ciona savignyi	65.40	0.00e+00	650.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	51.43	2.00e-132	466.00
IUUC-Cne-026933	Cryptococcus neoformans	59.95	1.00e-127	450.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	2.00e-117	417.00
IUUC-Dre-027470	Danio rerio	90.34	0.00e+00	871.00
IUUC-Dno-029629	Dasypus novemcinctus	83.11	0.00e+00	726.00
IUUC-Dor-030187	Dipodomys ordii	80.56	0.00e+00	794.00
IUUC-Dse-031502	Dothistroma septosporum	51.06	8.00e-126	444.00
IUUC-Dme-031858	Drosophila melanogaster	74.50	0.00e+00	677.00
IUUC-Ete-032562	Echinops telfairi	79.23	0.00e+00	757.00
IUUC-Eca-034210	Equus caballus	90.52	0.00e+00	895.00
IUUC-Fca-035839	Felis catus	86.29	0.00e+00	857.00
IUUC-Fal-036895	Ficedula albicollis	91.33	0.00e+00	904.00
IUUC-Fso-038420	Fusarium solani	50.51	2.00e-131	462.00
IUUC-Gmo-039544	Gadus morhua	96.58	0.00e+00	929.00
IUUC-Ggr-039774	Gaeumannomyces graminis	51.13	5.00e-132	464.00
IUUC-Gga-041025	Gallus gallus	91.13	0.00e+00	902.00
IUUC-Gac-041596	Gasterosteus aculeatus	98.99	0.00e+00	958.00
IUUC-Gma-042657	Glycine max	56.33	6.00e-134	470.00
IUUC-Ggo-045599	Gorilla gorilla	90.58	0.00e+00	859.00
IUUC-Hsa-046695	Homo sapiens	90.38	0.00e+00	892.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	2.00e-106	378.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	91.53	0.00e+00	900.00
IUUC-Kpa-049239	Komagataella pastoris	47.31	9.00e-123	433.00
IUUC-Lch-049827	Latimeria chalumnae	91.13	0.00e+00	867.00
IUUC-Lpe-051568	Leersia perrieri	64.69	2.00e-111	395.00
IUUC-Loc-052856	Lepisosteus oculatus	92.74	0.00e+00	895.00
IUUC-Laf-054321	Loxodonta africana	57.17	1.00e-131	462.00
IUUC-Mcc-055601	Macaca mulatta	90.93	0.00e+00	898.00
IUUC-Meu-056276	Macropus eugenii	67.58	3.00e-168	584.00
IUUC-Mor-057113	Magnaporthe oryzae	51.13	2.00e-131	462.00
IUUC-Mpo-057599	Magnaporthe poae	51.23	3.00e-132	465.00
IUUC-Mtr-057689	Medicago truncatula	56.19	2.00e-135	475.00
IUUC-Mla-059048	Melampsora laricipopulina	50.51	6.00e-120	424.00
IUUC-Mga-060097	Meleagris gallopavo	85.40	0.00e+00	831.00
IUUC-Mvi-060465	Microbotryum violaceum	51.66	3.00e-129	455.00
IUUC-Mmr-061151	Microcebus murinus	81.91	0.00e+00	770.00
IUUC-Mdo-063062	Monodelphis domestica	90.93	0.00e+00	901.00
IUUC-Mmu-063731	Mus musculus	90.52	0.00e+00	893.00
IUUC-Mac-065208	Musa acuminata	57.18	9.00e-129	453.00
IUUC-Mpu-066173	Mustela putorius furo	90.93	0.00e+00	897.00
IUUC-Mlu-068030	Myotis lucifugus	90.58	0.00e+00	890.00
IUUC-Nfi-068536	Neosartorya fischeri	50.10	2.00e-132	466.00
IUUC-Ncr-068734	Neurospora crassa	52.23	6.00e-134	471.00
IUUC-Nle-070163	Nomascus leucogenys	90.93	0.00e+00	898.00
IUUC-Opr-070974	Ochotona princeps	92.12	3.00e-154	536.00
IUUC-Ont-072272	Oreochromis niloticus	98.80	0.00e+00	954.00
IUUC-Oan-073634	Ornithorhynchus anatinus	96.60	4.00e-171	593.00
IUUC-Oba-075417	Oryza barthii	63.17	3.00e-111	395.00
IUUC-Obr-076123	Oryza brachyantha	57.95	5.00e-128	451.00
IUUC-Ogl-077294	Oryza glaberrima	52.70	5.00e-127	447.00
IUUC-Ogu-077996	Oryza glumaepatula	52.70	1.00e-125	442.00
IUUC-Oin-080172	Oryza indica	70.49	3.00e-126	445.00
IUUC-Olo-081068	Oryza longistaminata	70.49	4.00e-126	444.00
IUUC-Ome-081250	Oryza meridionalis	53.03	3.00e-127	448.00
IUUC-Oni-083048	Oryza nivara	52.70	5.00e-127	447.00
IUUC-Opu-083333	Oryza punctata	52.81	2.00e-126	446.00
IUUC-Oru-085001	Oryza rufipogon	52.70	5.00e-127	447.00
IUUC-Osa-086243	Oryza sativa	52.70	5.00e-127	447.00
IUUC-Ola-087094	Oryzias latipes	97.60	0.00e+00	907.00
IUUC-Oga-088911	Otolemur garnettii	90.93	0.00e+00	898.00
IUUC-Oar-089508	Ovis aries	90.93	0.00e+00	897.00
IUUC-Ptr-090967	Pan troglodytes	77.33	5.00e-165	573.00
IUUC-Pan-092147	Papio anubis	90.38	0.00e+00	892.00
IUUC-Psi-093702	Pelodiscus sinensis	91.16	0.00e+00	902.00
IUUC-Pma-094581	Petromyzon marinus	81.75	0.00e+00	764.00
IUUC-Pno-095139	Phaeosphaeria nodorum	60.37	8.00e-113	400.00
IUUC-Ppa-095366	Physcomitrella patens	56.33	8.00e-138	483.00
IUUC-Pfo-096309	Poecilia formosa	100.00	0.00e+00	966.00
IUUC-Pab-098762	Pongo abelii	74.55	0.00e+00	679.00
IUUC-Pop-098924	Populus trichocarpa	56.04	2.00e-133	468.00
IUUC-Pca-100565	Procavia capensis	88.16	0.00e+00	812.00
IUUC-Ppe-101924	Prunus persica	56.82	3.00e-136	478.00
IUUC-Pva-102602	Pteropus vampyrus	88.35	0.00e+00	852.00
IUUC-Pgr-103466	Puccinia graminis	50.86	7.00e-117	414.00
IUUC-Ptt-103888	Puccinia triticina	53.96	4.00e-107	382.00
IUUC-Pte-104097	Pyrenophora teres	49.22	2.00e-130	459.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	45.69	7.00e-112	397.00
IUUC-Rno-105028	Rattus norvegicus	90.52	0.00e+00	890.00
IUUC-Sce-106240	Saccharomyces cerevisiae	48.27	1.00e-93	337.00
IUUC-Sha-107107	Sarcophilus harrisii	76.94	0.00e+00	739.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	49.55	5.00e-117	414.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.62	1.00e-115	409.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	52.18	1.00e-127	449.00
IUUC-Smo-108878	Selaginella moellendorffii	59.59	1.00e-144	506.00
IUUC-Sit-110563	Setaria italica	53.25	7.00e-122	431.00
IUUC-Sly-111446	Solanum lycopersicum	55.60	5.00e-133	468.00
IUUC-Stu-112491	Solanum tuberosum	55.38	2.00e-132	465.00
IUUC-Sar-112962	Sorex araneus	78.63	1.00e-116	412.00
IUUC-Sbi-114489	Sorghum bicolor	54.75	1.00e-123	436.00
IUUC-Sre-115222	Sporisorium reilianum	48.49	2.00e-131	462.00
IUUC-Ssc-116171	Sus scrofa	90.93	0.00e+00	897.00
IUUC-Tgu-116878	Taeniopygia guttata	80.65	0.00e+00	768.00
IUUC-Tru-118222	Takifugu rubripes	96.99	0.00e+00	938.00
IUUC-Tni-119863	Tetraodon nigroviridis	98.39	0.00e+00	946.00
IUUC-Tca-121599	Theobroma cacao	57.63	2.00e-135	476.00
IUUC-Tre-122249	Trichoderma reesei	52.15	5.00e-133	468.00
IUUC-Tvi-122675	Trichoderma virens	52.34	7.00e-133	467.00
IUUC-Tae-123489	Triticum aestivum	53.59	6.00e-129	454.00
IUUC-Tur-126545	Triticum urartu	59.94	2.00e-103	369.00
IUUC-Tme-127151	Tuber melanosporum	54.43	9.00e-146	510.00
IUUC-Tbe-128056	Tupaia belangeri	85.36	2.00e-159	555.00
IUUC-Ttr-129055	Tursiops truncatus	89.78	0.00e+00	881.00
IUUC-Uma-129555	Ustilago maydis	48.49	1.00e-130	460.00
IUUC-Vda-130027	Verticillium dahliae	51.03	4.00e-133	468.00
IUUC-Vvi-131749	Vitis vinifera	55.43	1.00e-134	473.00
IUUC-Xtr-132808	Xenopus tropicalis	86.92	0.00e+00	854.00
IUUC-Yli-134584	Yarrowia lipolytica	61.83	2.00e-130	459.00
IUUC-Zma-135262	Zea mays	54.78	5.00e-124	437.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence