iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117625

Ensembl Protein ID

ENSTRUP00000001375.1

UniProt Accession

H2RML2; H2RML2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

phip

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000577.1	ENSTRUT00000001381.1	ENSTRUP00000001375.1
ENSTRUG00000000577.1	ENSTRUT00000001382.1	ENSTRUP00000001376.1
ENSTRUG00000000577.1	ENSTRUT00000001383.1	ENSTRUP00000001377.1
ENSTRUG00000000577.1	ENSTRUT00000001384.1	ENSTRUP00000001378.1
ENSTRUG00000000577.1	ENSTRUT00000001385.1	ENSTRUP00000001379.1
ENSTRUG00000000577.1	ENSTRUT00000001386.1	ENSTRUP00000001380.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-32	111.2	181	218
UBD/Beta-Prp	5.20e-65	220.8	182	395

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 181  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWGTDDGRLL 218
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s ++cv+f + ++ ++tgs+d  +k+w +++g ll++l gh ae++++  s +  +++ gs D+ti+vw l+t+ ++ +l+gh +s+
   Q: 182  HLSSVYCVTFDRTGRRIFTGSDDCLVKIWGTDDGRLLATLRGHAAEISDMAVSYENTMIAAGSCDKTIRVWCLQTCAPLAVLEGHAASI 270
           5567889*************************************************9******************************** PP
   S: 98   lslsfsp....sgdklvsGshdrtirvwdletgqclee......tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkl..lr 173
           +sl+fsp    s+ +l s+++d ti  w++++++          t++ + gv ++ ++ + g   l++Gs+D ++r++   +g+   + 
   Q: 271  TSLQFSPlcsgSKRYLSSTGADGTICFWQWDSRTLKFGqrpskfTERSRPGVQMICSSFSAGgMFLATGSTDHIIRVYYFGSGQPekIS 359
           *********877799************88888876655679999999999999988777777799*************99666651166 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
           +l++ htd+v s++f++ + ++vsgs+dgt ++w+lq
   Q: 360  ELES-HTDKVDSIQFSHCSDRFVSGSRDGTARIWQLQ 395
           7788.******************************98 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MASDSTHIAQ LTSELYFLIA RFLEAGPCQK AAETLIREVE EKELLPKRLD WTGQEHPGTY 60
ENLVKLYRHV SADHLLQVCS RVCPLLEREV PASVPGLTSL LGAGRQNLLR TSKSCKHVVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG ACAGTACACA CATCGCGCAG TTGACTTCTG GTGAGTAAAG GAGATTGTAA 60
CATGTGTCAC GGTCGTTGTA ATAGCCCCAC AATTTCCTCG GTGCCCTGTT CTAACGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	31.70	4.00e-63	237.00
IUUC-Atr-002600	Amborella trichopoda	31.84	5.00e-70	260.00
IUUC-Aly-006406	Arabidopsis lyrata	32.53	7.00e-71	263.00
IUUC-Ath-006801	Arabidopsis thaliana	32.19	3.00e-70	261.00
IUUC-Bdi-014797	Brachypodium distachyon	30.73	8.00e-58	219.00
IUUC-Bol-015737	Brassica oleracea	31.79	1.00e-73	272.00
IUUC-Bra-017961	Brassica rapa	31.75	3.00e-73	271.00
IUUC-Cpo-022077	Cavia porcellus	61.18	0.00e+00	2011.00
IUUC-Cho-024794	Choloepus hoffmanni	75.05	0.00e+00	708.00
IUUC-Csv-025813	Ciona savignyi	44.03	0.00e+00	641.00
IUUC-Dre-028029	Danio rerio	82.34	0.00e+00	1427.00
IUUC-Dor-030195	Dipodomys ordii	71.41	0.00e+00	1116.00
IUUC-Dme-031752	Drosophila melanogaster	52.33	0.00e+00	672.00
IUUC-Eeu-034688	Erinaceus europaeus	79.64	0.00e+00	1098.00
IUUC-Fal-037307	Ficedula albicollis	59.59	0.00e+00	1686.00
IUUC-Gmo-039451	Gadus morhua	78.86	0.00e+00	817.00
IUUC-Gma-043340	Glycine max	34.39	9.00e-65	243.00
IUUC-Ggo-045500	Gorilla gorilla	59.09	0.00e+00	1670.00
IUUC-Hvu-047706	Hordeum vulgare	31.46	2.00e-38	152.00
IUUC-Lpe-051619	Leersia perrieri	30.97	5.00e-67	250.00
IUUC-Loc-052672	Lepisosteus oculatus	67.89	0.00e+00	2338.00
IUUC-Mtr-058094	Medicago truncatula	32.12	1.00e-70	262.00
IUUC-Mac-065343	Musa acuminata	31.14	2.00e-73	271.00
IUUC-Opr-070971	Ochotona princeps	57.78	0.00e+00	691.00
IUUC-Ont-072221	Oreochromis niloticus	93.56	0.00e+00	1641.00
IUUC-Ocu-074033	Oryctolagus cuniculus	76.54	0.00e+00	1231.00
IUUC-Obr-076619	Oryza brachyantha	30.79	4.00e-68	254.00
IUUC-Oin-079669	Oryza indica	32.48	3.00e-53	203.00
IUUC-Olo-080755	Oryza longistaminata	32.27	1.00e-53	205.00
IUUC-Opu-083233	Oryza punctata	30.50	7.00e-63	236.00
IUUC-Ola-086648	Oryzias latipes	86.05	0.00e+00	2508.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.84	5.00e-55	210.00
IUUC-Ptr-091213	Pan troglodytes	59.16	0.00e+00	1665.00
IUUC-Pma-094427	Petromyzon marinus	62.84	3.00e-124	437.00
IUUC-Ppa-095793	Physcomitrella patens	29.89	3.00e-70	261.00
IUUC-Pfo-096191	Poecilia formosa	81.56	0.00e+00	2750.00
IUUC-Pop-099803	Populus trichocarpa	33.83	1.00e-76	281.00
IUUC-Pca-101128	Procavia capensis	80.90	0.00e+00	1209.00
IUUC-Ppe-101849	Prunus persica	30.78	3.00e-73	270.00
IUUC-Sit-110017	Setaria italica	31.93	2.00e-55	211.00
IUUC-Sly-111348	Solanum lycopersicum	31.59	4.00e-74	274.00
IUUC-Sar-113520	Sorex araneus	53.67	0.00e+00	860.00
IUUC-Sbi-114195	Sorghum bicolor	30.37	2.00e-57	217.00
IUUC-Tgu-116513	Taeniopygia guttata	59.33	0.00e+00	1683.00
IUUC-Tni-120716	Tetraodon nigroviridis	90.61	0.00e+00	3055.00
IUUC-Tca-121615	Theobroma cacao	31.31	6.00e-68	253.00
IUUC-Tae-125478	Triticum aestivum	30.98	9.00e-72	266.00
IUUC-Tur-126809	Triticum urartu	30.56	2.00e-69	258.00
IUUC-Tbe-127479	Tupaia belangeri	67.15	0.00e+00	996.00
IUUC-Vvi-131332	Vitis vinifera	32.52	2.00e-76	281.00
IUUC-Xma-134120	Xiphophorus maculatus	93.87	0.00e+00	1562.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence