iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000897

Ensembl Protein ID

EMT01694

UniProt Accession

R7VZF5; R7VZF5_AEGTA

Genbank Protein ID

EMT01694.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase 2

Genbank Nucleotide ID

KD643984

Gene Name

F775_09446

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_09446	EMT01694	EMT01694

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-49	169.8	880	1250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflaf 98
           G++N gNtCY+N+vLQ+L+++ +lr  +l   + +l        +g+l ++lqklf   +  ++ +++    ++++ ++k ++ f+    +D++ +l+ 
   Q: 880  GMRNGGNTCYFNAVLQSLLALDKLRARMLG--PDAL--------TGDLGQELQKLFIMTTntNGARGVLMSDKFFSYMCKRKSDFKPGVMEDSNNMLRS 968
           9*****************************..5554........578*********99988899999******************************** PP
   S: 99   lldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftke 197
           ll++l++e                              +++++++ lF+ q+ + +  +ec+++s ++e+ ldlsl++p k++    s++dcL+ +++ 
   Q: 969  LLNGLDNED----------------------------HSQPTMVESLFHSQVVKYVSSKECKHTSITFED-LDLSLAIPPKKHA---SIEDCLDLYVTG 1035
           *****9977............................6899***************************97.9**********98...*********987 PP
   S: 198  eelegenkyycekck........................................................................kkqeaekklklk 224
             +++   +yc+ c                                                                          +++a  +  ++
   Q: 1036 -VIDD---WYCTDCSaagnaslnqegttvndsqheqldnktymqkessypadeqtmttnqnngklpvldnnanqmeerhkklkeeekIYRTAIVQYHIT 1130
           .5554...*******9999999999999999999999999999999999999888888888888888888888777776655555443444******** PP
   S: 225  klPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.......ekgk......Wllf 309
           k  ++L+++LkRf +s+  ++  k++++v+f ++L +++f++    k+ +++kY+Liav+vH G +l++GH +ayv+        +  +      W+l 
   Q: 1131 KAAPILTIQLKRFDYSHP-DKLDKLQEHVSFQDTLHITKFMHLGHLKD-DECKYRLIAVIVHNGpTLREGHNFAYVRTsqiggqqQ--EshssptWFLA 1225
           ****************98.6667*******************988777.59***************************88777651..1456788**** PP
   S: 310  dDskVtevkeeevleetgstaYvlfYkr 337
           +D+++t+v+ eevle   ++aY+lfY+r
   Q: 1226 SDDSITQVSLEEVLE---CQAYILFYER 1250
           ***************...********98 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MMRIQDIRDG VSSLFVMLNK ESFVLFRIEF LVVLATVLFL LMFIMDVFRR HIRNTMMTAI 60
FSILDAVSDS IVLYLLGAMQ TASFTNQLFP VWALVLVSIR YNIDFISGYG VHDRHGRRFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGCGTA TCCAAGACAT CCGTGATGGT GTGTCATCCC TGTTCGTCAT GCTGAACAAG 60
GAATCATTCG TCCTGTTTCG GATCGAGTTT CTTGTGGTCC TGGCCACAGT CTTGTTCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0378--Hydrolase
KW-0472--Membrane
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR025315--DUF4220
IPR007658--DUF594
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF13968--DUF4220
PF04578--DUF594
PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_09446

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bdi-014073	Brachypodium distachyon	70.23	0.00e+00	1669.00
IUUC-Lpe-051081	Leersia perrieri	48.16	0.00e+00	867.00
IUUC-Oru-084758	Oryza rufipogon	53.69	0.00e+00	783.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence