iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035498

Ensembl Protein ID

ENSFCAP00000018157.1

UniProt Accession

M3WUX0; M3WUX0_FELCA

Genbank Protein ID

ENSFCAP00000018157

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02012781

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000024493.1	ENSFCAT00000031551.1	ENSFCAP00000018157.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	91.30	0.00e+00	727.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

TTIPLGDGPK RVPVTQQFPS QNLLSANSGQ AQRVLCPSNS SQRIPSQTQK LVSSHKPVQN 60
LKQKQLQATS VPRSVSRPLN NTQKSEQPLP SATGNNSEKE LTTKQKNEES KKRQWALEDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAATTCTC AAAATACCCC GCTTTTGTTC ATGAAGACCA TGACGTTTAT TTTTTCCCTC 60
TCAATCTAGA CCACAATTCC CCTTGGCGAT GGTCCAAAAC GTGTTCCAGT GACTCAGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	62.41	2.00e-104	371.00
IUUC-Aml-001426	Ailuropoda melanoleuca	95.71	0.00e+00	737.00
IUUC-Atr-002453	Amborella trichopoda	65.82	2.00e-107	381.00
IUUC-Apl-003626	Anas platyrhynchos	69.87	5.00e-157	547.00
IUUC-Aca-004602	Anolis carolinensis	70.57	3.00e-151	528.00
IUUC-Aly-005878	Arabidopsis lyrata	63.31	8.00e-105	372.00
IUUC-Ath-007117	Arabidopsis thaliana	65.20	7.00e-106	376.00
IUUC-Acl-008199	Aspergillus clavatus	54.36	6.00e-88	317.00
IUUC-Afl-008419	Aspergillus flavus	55.27	1.00e-86	313.00
IUUC-Afu-008751	Aspergillus fumigatus	53.67	7.00e-87	313.00
IUUC-Ani-009181	Aspergillus nidulans	51.43	5.00e-91	327.00
IUUC-Ang-009787	Aspergillus niger	49.12	2.00e-88	319.00
IUUC-Aor-009980	Aspergillus oryzae	55.27	1.00e-86	313.00
IUUC-Ate-010286	Aspergillus terreus	54.74	4.00e-87	315.00
IUUC-Ame-010849	Astyanax mexicanus	59.79	5.00e-129	454.00
IUUC-Bgr-012110	Blumeria graminis	57.89	1.00e-88	319.00
IUUC-Bta-013474	Bos taurus	89.77	0.00e+00	721.00
IUUC-Bci-013756	Botrytis cinerea	51.17	4.00e-96	344.00
IUUC-Bdi-014257	Brachypodium distachyon	63.10	7.00e-106	376.00
IUUC-Bol-016310	Brassica oleracea	62.06	4.00e-103	367.00
IUUC-Bra-017438	Brassica rapa	62.06	2.00e-104	371.00
IUUC-Cel-018157	Caenorhabditis elegans	62.88	5.00e-102	363.00
IUUC-Cja-019282	Callithrix jacchus	90.55	0.00e+00	703.00
IUUC-Cfa-020162	Canis familiaris	93.86	0.00e+00	735.00
IUUC-Cpo-021764	Cavia porcellus	83.97	0.00e+00	650.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	66.54	5.00e-107	380.00
IUUC-Csa-023694	Chlorocebus sabaeus	91.08	0.00e+00	666.00
IUUC-Cho-024350	Choloepus hoffmanni	96.94	7.00e-114	402.00
IUUC-Cin-025542	Ciona intestinalis	72.73	6.00e-118	416.00
IUUC-Csv-025873	Ciona savignyi	65.20	3.00e-118	417.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	47.03	5.00e-83	301.00
IUUC-Cne-026928	Cryptococcus neoformans	59.34	6.00e-96	344.00
IUUC-Cme-027336	Cyanidioschyzon merolae	69.37	3.00e-119	421.00
IUUC-Dre-028198	Danio rerio	62.67	5.00e-132	464.00
IUUC-Dno-029928	Dasypus novemcinctus	88.49	0.00e+00	643.00
IUUC-Dor-030238	Dipodomys ordii	78.77	0.00e+00	625.00
IUUC-Dse-031266	Dothistroma septosporum	53.97	8.00e-93	333.00
IUUC-Dme-032007	Drosophila melanogaster	61.07	6.00e-100	357.00
IUUC-Ete-032911	Echinops telfairi	67.57	1.00e-130	459.00
IUUC-Eca-033749	Equus caballus	94.36	0.00e+00	733.00
IUUC-Eeu-035170	Erinaceus europaeus	90.56	0.00e+00	719.00
IUUC-Fal-037397	Ficedula albicollis	70.28	6.00e-153	533.00
IUUC-Fox-037747	Fusarium oxysporum	46.81	4.00e-91	328.00
IUUC-Fso-038429	Fusarium solani	52.72	3.00e-89	322.00
IUUC-Gmo-039378	Gadus morhua	58.94	9.00e-127	446.00
IUUC-Ggr-039939	Gaeumannomyces graminis	59.21	1.00e-94	339.00
IUUC-Gga-040187	Gallus gallus	72.26	3.00e-151	528.00
IUUC-Gac-042223	Gasterosteus aculeatus	59.95	4.00e-134	471.00
IUUC-Gma-042870	Glycine max	64.86	1.00e-99	355.00
IUUC-Ggo-045617	Gorilla gorilla	90.54	0.00e+00	724.00
IUUC-Hsa-046968	Homo sapiens	91.30	0.00e+00	727.00
IUUC-Hvu-047072	Hordeum vulgare	53.62	8.00e-82	296.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	76.03	1.00e-168	585.00
IUUC-Kpa-049093	Komagataella pastoris	56.32	1.00e-77	283.00
IUUC-Lch-050346	Latimeria chalumnae	70.13	3.00e-148	517.00
IUUC-Lpe-051466	Leersia perrieri	65.33	6.00e-106	376.00
IUUC-Lma-053006	Leptosphaeria maculans	56.18	3.00e-89	322.00
IUUC-Laf-053422	Loxodonta africana	88.24	0.00e+00	700.00
IUUC-Mcc-055245	Macaca mulatta	91.64	0.00e+00	658.00
IUUC-Mor-056952	Magnaporthe oryzae	55.48	4.00e-91	328.00
IUUC-Mpo-057605	Magnaporthe poae	56.70	5.00e-95	341.00
IUUC-Mtr-057726	Medicago truncatula	64.96	9.00e-106	376.00
IUUC-Mla-059174	Melampsora laricipopulina	61.25	2.00e-99	355.00
IUUC-Mga-059562	Meleagris gallopavo	62.24	2.00e-118	419.00
IUUC-Mvi-060305	Microbotryum violaceum	59.85	3.00e-94	338.00
IUUC-Mmr-061588	Microcebus murinus	88.17	0.00e+00	711.00
IUUC-Mdo-061914	Monodelphis domestica	80.16	5.00e-176	610.00
IUUC-Mmu-063288	Mus musculus	83.12	0.00e+00	649.00
IUUC-Mac-064969	Musa acuminata	63.79	2.00e-106	378.00
IUUC-Mpu-066855	Mustela putorius furo	94.64	0.00e+00	729.00
IUUC-Mlu-068046	Myotis lucifugus	91.42	0.00e+00	704.00
IUUC-Nfi-068527	Neosartorya fischeri	50.30	3.00e-87	315.00
IUUC-Ncr-068678	Neurospora crassa	59.48	1.00e-92	333.00
IUUC-Nle-069848	Nomascus leucogenys	90.54	0.00e+00	723.00
IUUC-Opr-070589	Ochotona princeps	82.43	3.00e-180	624.00
IUUC-Ont-071733	Oreochromis niloticus	62.20	2.00e-126	445.00
IUUC-Oan-073399	Ornithorhynchus anatinus	83.86	3.00e-155	540.00
IUUC-Ocu-074063	Oryctolagus cuniculus	88.11	0.00e+00	695.00
IUUC-Oba-075264	Oryza barthii	62.46	5.00e-105	373.00
IUUC-Obr-076048	Oryza brachyantha	65.31	1.00e-104	372.00
IUUC-Ogl-077637	Oryza glaberrima	66.17	9.00e-105	372.00
IUUC-Ogu-078830	Oryza glumaepatula	63.19	3.00e-105	374.00
IUUC-Oin-079150	Oryza indica	62.46	2.00e-105	374.00
IUUC-Olo-080398	Oryza longistaminata	57.68	1.00e-82	299.00
IUUC-Ome-081544	Oryza meridionalis	55.15	4.00e-91	327.00
IUUC-Oni-082250	Oryza nivara	62.46	2.00e-105	374.00
IUUC-Opu-083638	Oryza punctata	62.80	1.00e-105	375.00
IUUC-Oru-084981	Oryza rufipogon	62.46	2.00e-105	375.00
IUUC-Osa-085961	Oryza sativa	62.46	2.00e-105	375.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.29	3.00e-112	397.00
IUUC-Oga-088891	Otolemur garnettii	88.71	0.00e+00	686.00
IUUC-Oar-090021	Ovis aries	89.51	0.00e+00	699.00
IUUC-Ptr-091458	Pan troglodytes	91.05	0.00e+00	726.00
IUUC-Pan-092546	Papio anubis	90.55	0.00e+00	663.00
IUUC-Psi-093280	Pelodiscus sinensis	75.82	2.00e-165	574.00
IUUC-Pma-094298	Petromyzon marinus	77.36	1.00e-121	428.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.02	6.00e-89	320.00
IUUC-Ppa-095855	Physcomitrella patens	62.28	1.00e-108	385.00
IUUC-Pfo-096428	Poecilia formosa	61.18	1.00e-130	459.00
IUUC-Pab-098696	Pongo abelii	90.05	0.00e+00	705.00
IUUC-Pop-099405	Populus trichocarpa	61.09	2.00e-105	375.00
IUUC-Pca-100740	Procavia capensis	81.33	0.00e+00	651.00
IUUC-Ppe-101854	Prunus persica	61.77	4.00e-106	377.00
IUUC-Pva-103212	Pteropus vampyrus	90.62	0.00e+00	698.00
IUUC-Pgr-103474	Puccinia graminis	63.26	3.00e-99	355.00
IUUC-Ptt-103933	Puccinia triticina	47.86	2.00e-63	236.00
IUUC-Pte-104089	Pyrenophora teres	48.53	9.00e-91	327.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	48.53	8.00e-91	327.00
IUUC-Rno-105057	Rattus norvegicus	83.63	0.00e+00	652.00
IUUC-Sha-107137	Sarcophilus harrisii	82.53	2.00e-180	624.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	55.05	5.00e-100	357.00
IUUC-Spo-108078	Schizosaccharomyces pombe	61.96	1.00e-103	369.00
IUUC-Smo-109288	Selaginella moellendorffii	66.79	2.00e-108	384.00
IUUC-Sit-110246	Setaria italica	62.12	2.00e-105	375.00
IUUC-Sly-111379	Solanum lycopersicum	64.08	3.00e-107	380.00
IUUC-Stu-112777	Solanum tuberosum	60.67	2.00e-105	375.00
IUUC-Sbi-114325	Sorghum bicolor	63.93	1.00e-104	372.00
IUUC-Sre-115203	Sporisorium reilianum	59.18	4.00e-81	295.00
IUUC-Ssc-115361	Sus scrofa	92.05	0.00e+00	736.00
IUUC-Tgu-116967	Taeniopygia guttata	72.80	1.00e-151	529.00
IUUC-Tru-117570	Takifugu rubripes	64.38	1.00e-137	483.00
IUUC-Tsy-119280	Tarsius syrichta	66.92	3.00e-134	471.00
IUUC-Tni-120721	Tetraodon nigroviridis	63.61	2.00e-136	478.00
IUUC-Tca-121494	Theobroma cacao	65.07	6.00e-105	373.00
IUUC-Tre-121869	Trichoderma reesei	56.21	7.00e-94	337.00
IUUC-Tvi-122510	Trichoderma virens	59.85	6.00e-92	330.00
IUUC-Tae-123071	Triticum aestivum	62.41	2.00e-104	371.00
IUUC-Tur-126240	Triticum urartu	62.41	6.00e-104	370.00
IUUC-Tme-126921	Tuber melanosporum	60.29	8.00e-98	350.00
IUUC-Tbe-127872	Tupaia belangeri	83.21	0.00e+00	648.00
IUUC-Ttr-129134	Tursiops truncatus	93.03	0.00e+00	693.00
IUUC-Uma-129412	Ustilago maydis	58.27	7.00e-80	291.00
IUUC-Vda-130003	Verticillium dahliae	54.25	7.00e-94	337.00
IUUC-Vvi-131272	Vitis vinifera	64.73	7.00e-106	376.00
IUUC-Xtr-132019	Xenopus tropicalis	67.27	2.00e-150	525.00
IUUC-Xma-134203	Xiphophorus maculatus	62.56	3.00e-134	471.00
IUUC-Yli-134503	Yarrowia lipolytica	53.85	2.00e-86	312.00
IUUC-Zma-135232	Zea mays	62.12	2.00e-105	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence