iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020171

Ensembl Protein ID

ENSCAFP00000013981.3

UniProt Accession

L7MTN8; L7MTN8_CANLF

Genbank Protein ID

ENSCAFP00000013981

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03016493

Gene Name

ITSN1; LOC100856635

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000032220.1	ENSCAFT00000015109.3	ENSCAFP00000013981.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.80e-68	224.7	1155	1205

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           v+  ydy+aqnddeL + kG ++ v+  ++ d +W+kg  e +g+ GlfP+n+v+
   Q: 1155 VIGVYDYSAQNDDELAFSKGQIINVL--NKDDPDWWKG--EVNGQVGLFPSNYVK 1205
           5667**********************..8889******..9*************8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGIGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCGATTA GCAAGGTAAA AGTGACAGAA CCATGGCTCA GTTTCCAACA CCTTTTGGAG 60
GTAAGTTTTT AAAGATTTTC TTTTTTTAAT GTATTCAAGA CTTACTTTCT TCTTTTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	3.00e-14	75.10
IUUC-Apl-003335	Anas platyrhynchos	91.56	0.00e+00	2276.00
IUUC-Aca-005130	Anolis carolinensis	89.31	0.00e+00	2247.00
IUUC-Ago-007935	Ashbya gossypii	36.84	3.00e-15	77.00
IUUC-Acl-008295	Aspergillus clavatus	30.46	9.00e-16	79.00
IUUC-Ang-009722	Aspergillus niger	32.08	1.00e-16	81.60
IUUC-Ate-010587	Aspergillus terreus	32.90	3.00e-17	84.00
IUUC-Bta-012863	Bos taurus	95.77	0.00e+00	2375.00
IUUC-Bdi-014016	Brachypodium distachyon	40.00	5.00e-14	73.60
IUUC-Bol-015187	Brassica oleracea	37.66	8.00e-11	62.40
IUUC-Cpo-021352	Cavia porcellus	88.08	0.00e+00	2873.00
IUUC-Cin-025435	Ciona intestinalis	51.81	0.00e+00	949.00
IUUC-Csv-026290	Ciona savignyi	58.04	0.00e+00	781.00
IUUC-Cme-027247	Cyanidioschyzon merolae	26.59	8.00e-11	62.00
IUUC-Dre-028623	Danio rerio	75.97	0.00e+00	1943.00
IUUC-Dno-030044	Dasypus novemcinctus	95.71	0.00e+00	2404.00
IUUC-Ete-032927	Echinops telfairi	98.20	0.00e+00	1037.00
IUUC-Fca-036419	Felis catus	97.61	0.00e+00	2424.00
IUUC-Fal-037236	Ficedula albicollis	89.50	0.00e+00	2256.00
IUUC-Gmo-039632	Gadus morhua	70.65	0.00e+00	1687.00
IUUC-Gga-040835	Gallus gallus	89.55	0.00e+00	2248.00
IUUC-Gac-041948	Gasterosteus aculeatus	72.23	0.00e+00	1816.00
IUUC-Gma-043381	Glycine max	35.64	3.00e-11	64.70
IUUC-Hvu-047530	Hordeum vulgare	33.14	1.00e-14	75.50
IUUC-Kpa-049215	Komagataella pastoris	40.71	6.00e-15	75.90
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Loc-052613	Lepisosteus oculatus	80.88	0.00e+00	1980.00
IUUC-Mcc-055720	Macaca mulatta	96.25	0.00e+00	2416.00
IUUC-Mlu-067025	Myotis lucifugus	66.95	0.00e+00	1489.00
IUUC-Nle-069448	Nomascus leucogenys	85.66	0.00e+00	1232.00
IUUC-Ont-071752	Oreochromis niloticus	72.59	0.00e+00	1806.00
IUUC-Ocu-073753	Oryctolagus cuniculus	93.46	0.00e+00	3034.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	3.00e-14	74.70
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	2.00e-14	74.70
IUUC-Oni-082167	Oryza nivara	41.67	5.00e-14	73.90
IUUC-Oru-084541	Oryza rufipogon	41.67	5.00e-14	73.90
IUUC-Olu-087698	Ostreococcus lucimarinus	27.16	3.00e-16	80.50
IUUC-Oga-088602	Otolemur garnettii	96.09	0.00e+00	2405.00
IUUC-Pfo-097486	Poecilia formosa	74.16	0.00e+00	1852.00
IUUC-Rno-106122	Rattus norvegicus	93.00	0.00e+00	2378.00
IUUC-Smo-108995	Selaginella moellendorffii	36.62	4.00e-08	53.10
IUUC-Sit-110414	Setaria italica	40.48	3.00e-14	74.30
IUUC-Sbi-114170	Sorghum bicolor	38.89	2.00e-14	74.70
IUUC-Tgu-117028	Taeniopygia guttata	90.45	0.00e+00	2295.00
IUUC-Tsy-119039	Tarsius syrichta	93.57	0.00e+00	1399.00
IUUC-Tae-123242	Triticum aestivum	41.67	4.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	40.00	3.00e-14	74.30
IUUC-Vpa-130687	Vicugna pacos	91.47	0.00e+00	1196.00
IUUC-Xtr-132905	Xenopus tropicalis	86.40	0.00e+00	2185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence