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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-106122
Ensembl Protein ID ENSRNOP00000044773.5
UniProt Accession D3ZV52; D3ZV52_RAT
Genbank Protein ID EDM10741.1
Protein Name Intersectin 1; Intersectin-1
Genbank Nucleotide ID AC123507
Gene Name Itsn1; rCG_58700
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000002001.8 ENSRNOT00000042750.5 ENSRNOP00000044773.5
ENSRNOG00000002001.8 ENSRNOT00000047843.6 ENSRNOP00000045513.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACRAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.30e-67 224.1 1151 1202
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL + kG ++ v+   ++d +W+kg  e +g+ GlfP+n+v+
   Q: 1151 QVIGMYDYTAQNDDELAFSKGQIINVL--SKEDPDWWKG--EVSGQVGLFPSNYVK 1202
           46678**********************..889*******..9*************8 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MAQFPTPFGG SLDIWAITVE ERAKHDQQFQ SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNKD GRMDQVEFSI AMKLIKLKLQ GYQLPPALPP VMKQQPAAIS SAPAFGIGGM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-106122|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGCCGCGC GCACCCGCCC GGAGATGAGG TGAGGAGCTG ACGCGGGCGG CCTGGCGCGC 60
GGGCGGGGGT CGGCGATGGC CGCCCGGGGT CGGGTCCAGC GGCCGGGCGC GCGTCCCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-106122|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3
Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3
Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000722 Aegilops tauschii 41.67 3.00e-14 75.10
IUUC-Aml-001218 Ailuropoda melanoleuca 92.06 0.00e+00 2312.00
IUUC-Apl-003335 Anas platyrhynchos 89.08 0.00e+00 2237.00
IUUC-Aca-005130 Anolis carolinensis 86.94 0.00e+00 2185.00
IUUC-Aly-005557 Arabidopsis lyrata 38.27 5.00e-12 67.40
IUUC-Ago-007935 Ashbya gossypii 32.84 9.00e-14 72.00
IUUC-Aor-010021 Aspergillus oryzae 29.38 9.00e-18 85.50
IUUC-Ame-011878 Astyanax mexicanus 75.62 0.00e+00 1913.00
IUUC-Bta-012863 Bos taurus 91.69 0.00e+00 2291.00
IUUC-Bdi-014016 Brachypodium distachyon 41.67 5.00e-14 73.90
IUUC-Cja-019012 Callithrix jacchus 93.25 0.00e+00 2303.00
IUUC-Cfa-020171 Canis familiaris 93.06 0.00e+00 2341.00
IUUC-Cpo-021352 Cavia porcellus 87.38 0.00e+00 2785.00
IUUC-Cho-024969 Choloepus hoffmanni 82.14 0.00e+00 1844.00
IUUC-Cin-025435 Ciona intestinalis 51.31 0.00e+00 952.00
IUUC-Csv-026290 Ciona savignyi 57.93 0.00e+00 790.00
IUUC-Dre-028623 Danio rerio 76.62 0.00e+00 1941.00
IUUC-Dno-030044 Dasypus novemcinctus 92.38 0.00e+00 2314.00
IUUC-Dor-030272 Dipodomys ordii 87.40 0.00e+00 2077.00
IUUC-Ete-032927 Echinops telfairi 97.80 0.00e+00 1034.00
IUUC-Eca-033469 Equus caballus 92.77 0.00e+00 2288.00
IUUC-Eeu-034977 Erinaceus europaeus 87.82 0.00e+00 1071.00
IUUC-Fca-036419 Felis catus 92.74 0.00e+00 2321.00
IUUC-Fal-037236 Ficedula albicollis 87.97 0.00e+00 2251.00
IUUC-Gmo-039632 Gadus morhua 70.03 0.00e+00 1680.00
IUUC-Gga-040835 Gallus gallus 87.14 0.00e+00 2194.00
IUUC-Gac-041948 Gasterosteus aculeatus 72.57 0.00e+00 1806.00
IUUC-Hsa-045699 Homo sapiens 93.33 0.00e+00 2357.00
IUUC-Hvu-047530 Hordeum vulgare 41.67 1.00e-13 71.60
IUUC-Itr-048773 Ictidomys tridecemlineatus 90.19 0.00e+00 2278.00
IUUC-Lch-050502 Latimeria chalumnae 76.35 0.00e+00 1616.00
IUUC-Lpe-051250 Leersia perrieri 41.67 2.00e-14 74.70
IUUC-Loc-052613 Lepisosteus oculatus 80.11 0.00e+00 1961.00
IUUC-Laf-053608 Loxodonta africana 91.39 0.00e+00 2310.00
IUUC-Mcc-055720 Macaca mulatta 93.70 0.00e+00 2342.00
IUUC-Meu-056445 Macropus eugenii 82.98 0.00e+00 1678.00
IUUC-Mla-059128 Melampsora laricipopulina 33.09 4.00e-40 161.00
IUUC-Mmr-061258 Microcebus murinus 93.41 0.00e+00 2322.00
IUUC-Mdo-062019 Monodelphis domestica 88.80 0.00e+00 2167.00
IUUC-Mmu-063885 Mus musculus 97.46 0.00e+00 2464.00
IUUC-Mlu-067025 Myotis lucifugus 66.22 0.00e+00 1454.00
IUUC-Nle-069448 Nomascus leucogenys 81.32 0.00e+00 1150.00
IUUC-Opr-070441 Ochotona princeps 88.25 0.00e+00 2049.00
IUUC-Ont-071752 Oreochromis niloticus 78.92 0.00e+00 1610.00
IUUC-Oan-073390 Ornithorhynchus anatinus 84.48 0.00e+00 2105.00
IUUC-Ocu-073753 Oryctolagus cuniculus 91.31 0.00e+00 2913.00
IUUC-Ogu-078849 Oryza glumaepatula 41.67 3.00e-14 74.70
IUUC-Olo-080259 Oryza longistaminata 41.67 2.00e-14 75.10
IUUC-Ome-081199 Oryza meridionalis 41.67 2.00e-14 75.10
IUUC-Oru-084541 Oryza rufipogon 41.67 4.00e-14 73.90
IUUC-Olu-087698 Ostreococcus lucimarinus 27.87 1.00e-15 78.60
IUUC-Oga-088602 Otolemur garnettii 93.86 0.00e+00 2353.00
IUUC-Oar-090195 Ovis aries 92.31 0.00e+00 2283.00
IUUC-Ptr-091363 Pan troglodytes 93.41 0.00e+00 2359.00
IUUC-Pan-092385 Papio anubis 92.73 0.00e+00 2321.00
IUUC-Pfo-097486 Poecilia formosa 73.30 0.00e+00 1846.00
IUUC-Pab-098281 Pongo abelii 82.22 0.00e+00 1976.00
IUUC-Pca-100270 Procavia capensis 82.24 0.00e+00 1192.00
IUUC-Pva-102335 Pteropus vampyrus 89.44 0.00e+00 2249.00
IUUC-Ptt-103973 Puccinia triticina 24.54 3.00e-26 115.00
IUUC-Sha-106851 Sarcophilus harrisii 89.05 0.00e+00 2177.00
IUUC-Sbi-114170 Sorghum bicolor 40.48 3.00e-14 74.70
IUUC-Sre-115028 Sporisorium reilianum 35.41 5.00e-33 137.00
IUUC-Tgu-117028 Taeniopygia guttata 88.30 0.00e+00 2268.00
IUUC-Tru-117789 Takifugu rubripes 75.35 0.00e+00 1821.00
IUUC-Tsy-119039 Tarsius syrichta 93.01 0.00e+00 1390.00
IUUC-Tni-119952 Tetraodon nigroviridis 73.33 0.00e+00 1712.00
IUUC-Tae-123242 Triticum aestivum 41.67 4.00e-14 74.30
IUUC-Tur-126623 Triticum urartu 41.67 3.00e-14 74.30
IUUC-Tbe-127754 Tupaia belangeri 81.57 0.00e+00 1645.00
IUUC-Ttr-129178 Tursiops truncatus 91.49 0.00e+00 2303.00
IUUC-Uma-129456 Ustilago maydis 32.05 3.00e-32 135.00
IUUC-Vpa-130687 Vicugna pacos 85.75 0.00e+00 1129.00
IUUC-Xtr-132905 Xenopus tropicalis 84.45 0.00e+00 2142.00
Created Date 25-Jun-2017

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