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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108029
Ensembl Protein ID SPAC17H9.10c.1:pep
UniProt Accession O13807; DDB1_SCHPO
Genbank Protein ID CAB11219.1
Protein Name DNA damage-binding protein 1; Damage-specific DNA-binding protein 1
Genbank Nucleotide ID CU329670
Gene Name ddb1; SPAC17H9.10c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC17H9.10c SPAC17H9.10c.1 SPAC17H9.10c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/DCX/DDB1 27.31 1.00e-117 421.00 IUUC-Ath-007151
E3 adaptor/Cullin RING/DCX/DDB1 22.61 7.00e-57 219.00 IUUC-Cel-018239
E3 adaptor/Cullin RING/DCX/DDB1 26.33 7.00e-89 326.00 IUUC-Dme-031940
E3 adaptor/Cullin RING/DCX/DDB1 25.94 1.00e-99 362.00 IUUC-Hsa-046709
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Component of an E3 ubiquitin-protein ligase that includes cul4 (By similarity). Required for ubiquitination and the subsequent degradation of the DNA replication licensing factor cdt1 and of the ribonucleotide reductase inhibitor spd1. Also required for transcription-coupled nucleotide excision repair.
 Component of an E3 ubiquitin-protein ligase that includes cul4 (By similarity). Required for ubiquitination and the subsequent degradation of the DNA replication licensing factor cdt1 and of the ribonucleotide reductase inhibitor spd1. Also required for transcription-coupled nucleotide excision repair.
Protein Sequence
(Fasta)
MTYVTYLHKP SSIRNAVFCK FVNASSWNVI VAKVNCLEVY SYENNRLCLI TSANIFAKIV 60
NVKAFKPVSS PTDHIIVATD SFRYFTLFWD ANDNTVSNGI KIQDCSERSL RESQSGPLLL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108029|E3,DDB1|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGATACTTA AGGATAAATA TTATATAATA CCTAAGATTG AACGAACTAA TGTTTTTTTT 60
TAATATTCCT AAGAATATCC TGTTAATGCA ATCACTTTTT TAATAACATT CATAAAGTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108029|E3,DDB1|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
Pfam

PF03178--CPSF_A
Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0070912--C:Ddb1-Ckn1 complex
GO:0070913--C:Ddb1-Wdr21 complex
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0035861--C:site of double-strand break
GO:0003684--F:damaged DNA binding
GO:0032403--F:protein complex binding
GO:0006279--P:premeiotic DNA replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0090052--P:regulation of chromatin silencing at centromere
GO:0090054--P:regulation of chromatin silencing at silent mating-type cassette
GO:0006283--P:transcription-coupled nucleotide-excision repair
KEGG spo:SPAC17H9.10c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000120 Aegilops tauschii 25.92 9.00e-109 386.00
IUUC-Aml-002096 Ailuropoda melanoleuca 26.11 2.00e-101 362.00
IUUC-Atr-002742 Amborella trichopoda 26.45 3.00e-117 414.00
IUUC-Apl-003624 Anas platyrhynchos 26.45 6.00e-94 337.00
IUUC-Aca-005085 Anolis carolinensis 26.62 8.00e-103 366.00
IUUC-Aly-005782 Arabidopsis lyrata 26.93 2.00e-120 425.00
IUUC-Ath-007151 Arabidopsis thaliana 26.99 1.00e-118 419.00
IUUC-Acl-008149 Aspergillus clavatus 27.07 1.00e-96 346.00
IUUC-Afl-008549 Aspergillus flavus 26.54 2.00e-95 342.00
IUUC-Afu-009076 Aspergillus fumigatus 27.59 2.00e-104 372.00
IUUC-Ani-009302 Aspergillus nidulans 27.06 5.00e-92 330.00
IUUC-Ang-009636 Aspergillus niger 26.74 3.00e-80 291.00
IUUC-Aor-010073 Aspergillus oryzae 26.84 2.00e-103 368.00
IUUC-Ate-010422 Aspergillus terreus 27.36 2.00e-98 352.00
IUUC-Ame-011643 Astyanax mexicanus 23.75 1.00e-80 292.00
IUUC-Bgr-012164 Blumeria graminis 24.42 3.00e-79 288.00
IUUC-Bta-012494 Bos taurus 26.01 3.00e-101 361.00
IUUC-Bci-013957 Botrytis cinerea 24.87 1.00e-84 306.00
IUUC-Bdi-014186 Brachypodium distachyon 26.10 4.00e-112 397.00
IUUC-Bol-015922 Brassica oleracea 26.95 5.00e-117 413.00
IUUC-Bra-017988 Brassica rapa 27.09 2.00e-119 422.00
IUUC-Cel-018239 Caenorhabditis elegans 22.65 3.00e-57 215.00
IUUC-Cja-019165 Callithrix jacchus 26.11 1.00e-101 362.00
IUUC-Cfa-020406 Canis familiaris 26.11 2.00e-101 362.00
IUUC-Cpo-022154 Cavia porcellus 25.77 2.00e-99 355.00
IUUC-Cre-022557 Chlamydomonas reinhardtii 23.47 2.00e-71 262.00
IUUC-Csa-024061 Chlorocebus sabaeus 26.11 1.00e-101 362.00
IUUC-Cho-024554 Choloepus hoffmanni 24.11 7.00e-32 130.00
IUUC-Cin-025466 Ciona intestinalis 24.89 2.00e-90 325.00
IUUC-Csv-026370 Ciona savignyi 24.71 3.00e-74 271.00
IUUC-Cgl-026595 Colletotrichum gloeosporioides 25.36 3.00e-86 311.00
IUUC-Cme-027342 Cyanidioschyzon merolae 22.04 1.00e-46 180.00
IUUC-Dre-027448 Danio rerio 25.83 2.00e-45 175.00
IUUC-Dno-029794 Dasypus novemcinctus 25.70 1.00e-90 326.00
IUUC-Dor-030789 Dipodomys ordii 21.59 4.00e-14 72.00
IUUC-Dse-031491 Dothistroma septosporum 26.52 5.00e-101 360.00
IUUC-Dme-031940 Drosophila melanogaster 26.33 9.00e-88 316.00
IUUC-Ete-032913 Echinops telfairi 24.40 4.00e-23 101.00
IUUC-Eca-033777 Equus caballus 26.11 6.00e-100 357.00
IUUC-Eeu-034900 Erinaceus europaeus 23.10 4.00e-33 135.00
IUUC-Fca-035869 Felis catus 26.11 2.00e-101 362.00
IUUC-Fal-036777 Ficedula albicollis 26.38 2.00e-98 352.00
IUUC-Fox-037954 Fusarium oxysporum 25.04 4.00e-80 291.00
IUUC-Fso-038292 Fusarium solani 25.42 1.00e-82 299.00
IUUC-Gmo-038815 Gadus morhua 31.11 2.00e-36 145.00
IUUC-Ggr-039907 Gaeumannomyces graminis 25.00 5.00e-85 307.00
IUUC-Gga-040995 Gallus gallus 26.54 2.00e-100 358.00
IUUC-Gac-042390 Gasterosteus aculeatus 26.09 4.00e-93 334.00
IUUC-Gma-042743 Glycine max 26.67 5.00e-116 410.00
IUUC-Ggo-044891 Gorilla gorilla 26.04 2.00e-100 358.00
IUUC-Hsa-046709 Homo sapiens 26.11 1.00e-101 362.00
IUUC-Hvu-047504 Hordeum vulgare 26.77 1.00e-113 402.00
IUUC-Itr-048678 Ictidomys tridecemlineatus 26.19 1.00e-101 363.00
IUUC-Lch-050565 Latimeria chalumnae 26.30 1.00e-102 366.00
IUUC-Lpe-051260 Leersia perrieri 26.55 1.00e-111 395.00
IUUC-Loc-052091 Lepisosteus oculatus 26.07 2.00e-69 255.00
IUUC-Lma-053246 Leptosphaeria maculans 25.77 7.00e-95 340.00
IUUC-Laf-053502 Loxodonta africana 26.19 1.00e-101 362.00
IUUC-Mcc-054802 Macaca mulatta 26.21 4.00e-99 354.00
IUUC-Meu-056808 Macropus eugenii 25.00 9.00e-54 203.00
IUUC-Mor-057253 Magnaporthe oryzae 27.62 2.00e-42 166.00
IUUC-Mpo-057562 Magnaporthe poae 25.38 1.00e-88 319.00
IUUC-Mtr-057743 Medicago truncatula 27.06 2.00e-115 408.00
IUUC-Mla-059154 Melampsora laricipopulina 21.56 9.00e-41 160.00
IUUC-Mga-059824 Meleagris gallopavo 26.93 1.00e-90 325.00
IUUC-Mvi-060279 Microbotryum violaceum 22.52 1.00e-66 246.00
IUUC-Mmr-061215 Microcebus murinus 25.94 7.00e-99 353.00
IUUC-Mdo-062028 Monodelphis domestica 26.09 7.00e-75 273.00
IUUC-Mmu-064327 Mus musculus 26.02 5.00e-101 360.00
IUUC-Mac-065445 Musa acuminata 27.01 2.00e-115 408.00
IUUC-Mpu-065814 Mustela putorius furo 25.88 3.00e-95 341.00
IUUC-Mlu-067136 Myotis lucifugus 26.19 4.00e-101 361.00
IUUC-Nfi-068355 Neosartorya fischeri 27.42 5.00e-100 357.00
IUUC-Ncr-068620 Neurospora crassa 25.86 3.00e-90 324.00
IUUC-Nle-069566 Nomascus leucogenys 26.05 4.00e-99 354.00
IUUC-Opr-070915 Ochotona princeps 25.22 3.00e-65 241.00
IUUC-Ont-071753 Oreochromis niloticus 26.11 2.00e-100 358.00
IUUC-Oan-073187 Ornithorhynchus anatinus 26.80 6.00e-93 333.00
IUUC-Ocu-074619 Oryctolagus cuniculus 26.11 9.00e-102 363.00
IUUC-Oba-075091 Oryza barthii 25.66 1.00e-69 256.00
IUUC-Obr-076425 Oryza brachyantha 26.24 9.00e-110 390.00
IUUC-Ogu-078794 Oryza glumaepatula 26.46 2.00e-113 401.00
IUUC-Oin-079725 Oryza indica 26.45 1.00e-111 395.00
IUUC-Olo-080842 Oryza longistaminata 26.27 1.00e-96 347.00
IUUC-Ome-081818 Oryza meridionalis 26.55 6.00e-114 404.00
IUUC-Oni-082879 Oryza nivara 26.21 1.00e-109 389.00
IUUC-Opu-083361 Oryza punctata 26.28 2.00e-111 395.00
IUUC-Oru-084781 Oryza rufipogon 26.55 7.00e-114 403.00
IUUC-Osa-086293 Oryza sativa 26.55 7.00e-114 403.00
IUUC-Ola-086881 Oryzias latipes 26.26 1.00e-99 356.00
IUUC-Olu-087674 Ostreococcus lucimarinus 27.02 1.00e-100 359.00
IUUC-Oga-089056 Otolemur garnettii 26.11 1.00e-101 362.00
IUUC-Oar-089457 Ovis aries 26.10 7.00e-99 353.00
IUUC-Ptr-091179 Pan troglodytes 26.08 2.00e-98 352.00
IUUC-Pan-092019 Papio anubis 25.85 3.00e-99 354.00
IUUC-Psi-093407 Pelodiscus sinensis 26.73 6.00e-98 350.00
IUUC-Pma-094272 Petromyzon marinus 25.40 9.00e-85 306.00
IUUC-Pno-094864 Phaeosphaeria nodorum 26.08 2.00e-98 352.00
IUUC-Ppa-095885 Physcomitrella patens 28.80 2.00e-120 424.00
IUUC-Pfo-096083 Poecilia formosa 26.32 4.00e-101 360.00
IUUC-Pab-098652 Pongo abelii 25.38 1.00e-89 322.00
IUUC-Pop-099593 Populus trichocarpa 26.95 6.00e-111 393.00
IUUC-Pca-100189 Procavia capensis 25.54 4.00e-46 178.00
IUUC-Ppe-101987 Prunus persica 26.85 3.00e-110 391.00
IUUC-Pva-102605 Pteropus vampyrus 26.11 9.00e-101 359.00
IUUC-Pgr-103659 Puccinia graminis 21.64 7.00e-37 147.00
IUUC-Ptt-103884 Puccinia triticina 21.29 2.00e-20 92.80
IUUC-Pte-104233 Pyrenophora teres 27.03 9.00e-109 386.00
IUUC-Pyt-104454 Pyrenophora triticirepentis 27.31 3.00e-107 381.00
IUUC-Rno-106004 Rattus norvegicus 26.19 4.00e-101 360.00
IUUC-Sha-106726 Sarcophilus harrisii 26.24 2.00e-86 312.00
IUUC-Sja-107864 Schizosaccharomyces japonicus 37.57 0.00e+00 739.00
IUUC-Ssl-108441 Sclerotinia sclerotiorum 25.83 2.00e-77 282.00
IUUC-Smo-108862 Selaginella moellendorffii 27.46 3.00e-124 437.00
IUUC-Sit-109735 Setaria italica 26.18 6.00e-110 390.00
IUUC-Sly-111520 Solanum lycopersicum 26.96 2.00e-113 401.00
IUUC-Sar-113606 Sorex araneus 30.73 3.00e-16 79.00
IUUC-Sbi-114539 Sorghum bicolor 26.09 2.00e-107 382.00
IUUC-Sre-114936 Sporisorium reilianum 18.55 4.00e-19 89.00
IUUC-Ssc-116038 Sus scrofa 26.22 4.00e-101 361.00
IUUC-Tgu-117512 Taeniopygia guttata 26.45 2.00e-99 355.00
IUUC-Tru-117593 Takifugu rubripes 26.20 2.00e-100 358.00
IUUC-Tsy-119513 Tarsius syrichta 25.71 1.00e-39 156.00
IUUC-Tni-120551 Tetraodon nigroviridis 27.60 2.00e-50 192.00
IUUC-Tca-121505 Theobroma cacao 26.92 2.00e-112 398.00
IUUC-Tre-122136 Trichoderma reesei 24.86 1.00e-60 226.00
IUUC-Tvi-122512 Trichoderma virens 24.41 5.00e-82 297.00
IUUC-Tae-122891 Triticum aestivum 26.86 4.00e-114 404.00
IUUC-Tur-126451 Triticum urartu 26.86 2.00e-100 358.00
IUUC-Tme-127057 Tuber melanosporum 23.97 1.00e-77 283.00
IUUC-Ttr-128891 Tursiops truncatus 26.11 1.00e-59 223.00
IUUC-Uma-129583 Ustilago maydis 16.94 4.00e-11 62.80
IUUC-Vda-129870 Verticillium dahliae 24.29 4.00e-86 311.00
IUUC-Vpa-130117 Vicugna pacos 25.44 3.00e-60 225.00
IUUC-Vvi-131033 Vitis vinifera 27.11 6.00e-115 406.00
IUUC-Xtr-131987 Xenopus tropicalis 25.73 2.00e-97 348.00
IUUC-Xma-134117 Xiphophorus maculatus 25.68 1.00e-95 342.00
IUUC-Zma-134758 Zea mays 26.28 1.00e-111 395.00
Created Date 25-Jun-2017

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