iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000016808.3	ENSMMUT00000023617.3	ENSMMUP00000022098.3
ENSMMUG00000016808.3	ENSMMUT00000046690.2	ENSMMUP00000039720.2
ENSMMUG00000016808.3	ENSMMUT00000023616.3	ENSMMUP00000022097.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.00e-11	42.9	104	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek.wiCpkCr 52
           +vC +C+e++++   ++v C+kC + +H+ C+ + +++++ +s++ w C++C 
   Q: 104  MVCTICQEEYSEAPnEMVICDKCGQGYHQLCHTPHIDSSVIDSDEkWLCRQCV 156
           79********987569********************9999888777******7 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MKKDSTGAGN SLVHKRSPLR RNQKTPTSLT KLSLQDGHKA KKPACKFEEG QDVLARWSDG 60
LFYLGTIKKI NILKQSCFII FEDSSKSWVL WKDIQTGATG SGEMVCTICQ EEYSEAPNEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAAAAGT TTAACATATA AAATATCCCA CTGGTATAAA ATAAGCTCTA TAAGTAAGTC 60
TTATATATGG TCTTTTATTC TCTAAACAGA GACTCTACAG GGGCAGGTAA TTCACTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025894--Mtf2_C_dom
IPR002999--Tudor
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF14061--Mtf2_C
PF00628--PHD

SMART

SM00249--PHD
SM00333--TUDOR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0035098--C:ESC/E(Z) complex
GO:0008270--F:zinc ion binding
GO:0061086--P:negative regulation of histone H3-K27 methylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0061087--P:positive regulation of histone H3-K27 methylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0007379--P:segment specification
GO:0048863--P:stem cell differentiation
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001293	Ailuropoda melanoleuca	99.32	0.00e+00	1173.00
IUUC-Apl-004128	Anas platyrhynchos	90.42	0.00e+00	1100.00
IUUC-Aca-004646	Anolis carolinensis	88.97	0.00e+00	982.00
IUUC-Bta-012598	Bos taurus	99.19	0.00e+00	967.00
IUUC-Cja-019930	Callithrix jacchus	99.66	0.00e+00	1203.00
IUUC-Cfa-020413	Canis familiaris	99.16	0.00e+00	1171.00
IUUC-Csa-023605	Chlorocebus sabaeus	99.66	0.00e+00	1179.00
IUUC-Csv-026067	Ciona savignyi	52.30	1.00e-98	352.00
IUUC-Dre-028327	Danio rerio	63.61	0.00e+00	701.00
IUUC-Dno-029487	Dasypus novemcinctus	95.45	0.00e+00	1130.00
IUUC-Dme-031808	Drosophila melanogaster	32.74	5.00e-47	183.00
IUUC-Eca-034332	Equus caballus	98.65	0.00e+00	1191.00
IUUC-Fca-036088	Felis catus	99.16	0.00e+00	1170.00
IUUC-Fal-036851	Ficedula albicollis	90.89	0.00e+00	920.00
IUUC-Gmo-038940	Gadus morhua	64.80	6.00e-144	504.00
IUUC-Gga-041162	Gallus gallus	89.95	0.00e+00	1097.00
IUUC-Gac-041758	Gasterosteus aculeatus	58.13	1.00e-140	493.00
IUUC-Ggo-044658	Gorilla gorilla	99.66	0.00e+00	1180.00
IUUC-Hsa-045895	Homo sapiens	99.66	0.00e+00	1180.00
IUUC-Itr-047940	Ictidomys tridecemlineatus	98.82	0.00e+00	1193.00
IUUC-Lch-050577	Latimeria chalumnae	79.97	0.00e+00	895.00
IUUC-Loc-051747	Lepisosteus oculatus	68.73	0.00e+00	793.00
IUUC-Laf-054500	Loxodonta africana	99.16	0.00e+00	1197.00
IUUC-Mga-059203	Meleagris gallopavo	90.08	0.00e+00	1094.00
IUUC-Mmr-061070	Microcebus murinus	99.49	0.00e+00	1165.00
IUUC-Mdo-061878	Monodelphis domestica	95.53	0.00e+00	961.00
IUUC-Mmu-063700	Mus musculus	97.64	0.00e+00	1178.00
IUUC-Mpu-066250	Mustela putorius furo	98.99	0.00e+00	1170.00
IUUC-Mlu-067694	Myotis lucifugus	98.31	0.00e+00	1192.00
IUUC-Nle-069777	Nomascus leucogenys	99.32	0.00e+00	1202.00
IUUC-Ont-072183	Oreochromis niloticus	53.62	1.00e-167	583.00
IUUC-Oan-073204	Ornithorhynchus anatinus	97.11	4.00e-144	503.00
IUUC-Ocu-074279	Oryctolagus cuniculus	98.99	0.00e+00	1196.00
IUUC-Ola-087332	Oryzias latipes	55.66	5.00e-136	478.00
IUUC-Oga-089023	Otolemur garnettii	55.46	6.00e-115	407.00
IUUC-Oar-089543	Ovis aries	98.99	0.00e+00	1171.00
IUUC-Ptr-090676	Pan troglodytes	99.66	0.00e+00	1180.00
IUUC-Pan-092568	Papio anubis	99.83	0.00e+00	1180.00
IUUC-Psi-092976	Pelodiscus sinensis	90.92	0.00e+00	1114.00
IUUC-Pma-094138	Petromyzon marinus	64.16	9.00e-135	473.00
IUUC-Pfo-097187	Poecilia formosa	50.89	4.00e-158	551.00
IUUC-Pab-097543	Pongo abelii	99.66	0.00e+00	1180.00
IUUC-Pca-100289	Procavia capensis	87.74	0.00e+00	851.00
IUUC-Pva-103007	Pteropus vampyrus	54.95	3.00e-103	369.00
IUUC-Rno-105075	Rattus norvegicus	96.96	0.00e+00	1172.00
IUUC-Sha-106522	Sarcophilus harrisii	96.67	7.00e-122	429.00
IUUC-Ssc-116220	Sus scrofa	98.82	0.00e+00	1169.00
IUUC-Tgu-117230	Taeniopygia guttata	88.61	0.00e+00	1060.00
IUUC-Tru-118228	Takifugu rubripes	56.06	1.00e-158	553.00
IUUC-Tsy-119045	Tarsius syrichta	98.82	0.00e+00	1155.00
IUUC-Tni-120342	Tetraodon nigroviridis	56.47	3.00e-176	611.00
IUUC-Ttr-128691	Tursiops truncatus	98.82	0.00e+00	1167.00
IUUC-Vpa-130085	Vicugna pacos	57.04	1.00e-48	186.00
IUUC-Xtr-132767	Xenopus tropicalis	74.54	0.00e+00	882.00
IUUC-Xma-133635	Xiphophorus maculatus	50.73	1.00e-158	553.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence