iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aly-006020

Ensembl Protein ID

fgenesh2_kg.2__264__AT1G62020.1

UniProt Accession

D7KUU6; D7KUU6_ARALL

Genbank Protein ID

EFH64300.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

GL348714

Gene Name

ARALYDRAFT_475134

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.2__264__AT1G62020.1	fgenesh2_kg.2__264__AT1G62020.1	fgenesh2_kg.2__264__AT1G62020.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-39	133.3	50	86
UBD/Beta-Prp	1.70e-78	264.5	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H+++v++++f ++ +l+vsG+dD +ikvW+++ +++l
   Q: 50   HEGPVRGVHFhNSqPLFVSGGDDYKIKVWNYKNHRCL 86
           9*********9777*****************999997 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdl 81
           t +++++++++ + f+p++++++++  +g i++wd+++g+l+ ++ +he++v+ v f+++++++v+g++D+ ikvw++
   Q: 3    TKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHEGPVRGVHFHNSQPLFVSGGDDYKIKVWNY 80
           67889999********************************************************************** PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDr 159
           ++  c+ tl gh d++++++f+ +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+
   Q: 81   KNHRCLFTLLGHLDYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCVS-VLTGHNHYVMCASFHPKEDLVVSASLDQ 157
           *************************************************.**************************** PP
   S: 160  tvrlWdl..........................ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           tvr+Wd+                            + +++   +gh++ v++ +f+++ + +vsg++d++vklw + +
   Q: 158  TVRVWDIgalrkktvspaddimrltqmnsdlfgGVDAIVKYVLEGHDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNE 235
           ****************99999977766666666333333333555********************************8 PP
   S: 212  gec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgseds 287
           ++   v+tl+gh +nv+sv f+ +++++vs s+D+sir+Wd ++++ l+t+ +++++++  av +++ n l++g  ds
   Q: 236  TKAweVDTLRGHMNNVSSVMFHAKQDIIVSNSEDKSIRVWDATKRTGLQTFRREHDRFWILAV-HPEMNLLAAG-HDS 311
           87778**********************************************************.6766655555.689 PP
   S: 288  kvniwklkknep 299
              ++kl++++p
   Q: 312  GMIVFKLERERP 323
           999999988765 PP

Organism

Arabidopsis lyrata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPK RPWILASLHS GVIQLWDYRM GTLIDRFDEH EGPVRGVHFH 60
NSQPLFVSGG DDYKIKVWNY KNHRCLFTLL GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGACAA AATTCGAAAC CAAGAGTAAC AGAGTTAAGG GTCTGAGCTT TCACCCTAAA 60
CGACCATGGA TTCTCGCGAG TTTGCACAGT GGTGTGATCC AGCTTTGGGA TTATCGTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005886--C:plasma membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

aly:ARALYDRAFT_475134

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	77.19	0.00e+00	1970.00
IUUC-Aml-001758	Ailuropoda melanoleuca	54.95	0.00e+00	1365.00
IUUC-Atr-002493	Amborella trichopoda	80.71	0.00e+00	1999.00
IUUC-Apl-003385	Anas platyrhynchos	49.07	0.00e+00	1043.00
IUUC-Aca-005154	Anolis carolinensis	79.41	1.00e-96	344.00
IUUC-Ath-007058	Arabidopsis thaliana	98.85	0.00e+00	2330.00
IUUC-Ago-007992	Ashbya gossypii	43.11	0.00e+00	971.00
IUUC-Acl-008027	Aspergillus clavatus	54.59	0.00e+00	966.00
IUUC-Afu-008964	Aspergillus fumigatus	47.00	0.00e+00	1128.00
IUUC-Ang-009756	Aspergillus niger	46.71	0.00e+00	1122.00
IUUC-Ate-010302	Aspergillus terreus	47.32	0.00e+00	1162.00
IUUC-Ame-011229	Astyanax mexicanus	53.36	0.00e+00	1330.00
IUUC-Bgr-012300	Blumeria graminis	47.07	0.00e+00	1088.00
IUUC-Bta-012524	Bos taurus	55.43	0.00e+00	1357.00
IUUC-Bci-013781	Botrytis cinerea	46.46	0.00e+00	1122.00
IUUC-Bdi-014549	Brachypodium distachyon	77.17	0.00e+00	2004.00
IUUC-Bol-015925	Brassica oleracea	92.30	0.00e+00	2218.00
IUUC-Bra-016978	Brassica rapa	92.95	0.00e+00	2231.00
IUUC-Cel-018115	Caenorhabditis elegans	54.64	0.00e+00	944.00
IUUC-Cja-019107	Callithrix jacchus	54.64	0.00e+00	1345.00
IUUC-Cfa-020675	Canis familiaris	54.63	0.00e+00	1339.00
IUUC-Cpo-021813	Cavia porcellus	55.51	0.00e+00	1378.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	71.26	0.00e+00	1264.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.43	0.00e+00	1378.00
IUUC-Cho-024704	Choloepus hoffmanni	43.60	3.00e-173	602.00
IUUC-Cin-025572	Ciona intestinalis	50.56	0.00e+00	1244.00
IUUC-Csv-025864	Ciona savignyi	57.74	0.00e+00	993.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	53.97	0.00e+00	972.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.67	2.00e-145	509.00
IUUC-Dre-027421	Danio rerio	54.21	0.00e+00	1358.00
IUUC-Dno-029303	Dasypus novemcinctus	55.56	0.00e+00	1382.00
IUUC-Dor-030290	Dipodomys ordii	52.90	5.00e-165	575.00
IUUC-Dse-031543	Dothistroma septosporum	46.59	0.00e+00	1075.00
IUUC-Dme-031945	Drosophila melanogaster	61.18	0.00e+00	1040.00
IUUC-Ete-032873	Echinops telfairi	53.51	0.00e+00	1210.00
IUUC-Eca-033773	Equus caballus	54.55	0.00e+00	1338.00
IUUC-Eeu-034874	Erinaceus europaeus	40.86	0.00e+00	653.00
IUUC-Fca-035739	Felis catus	53.90	0.00e+00	1337.00
IUUC-Fal-037263	Ficedula albicollis	50.77	0.00e+00	1203.00
IUUC-Fox-037738	Fusarium oxysporum	46.25	0.00e+00	1130.00
IUUC-Fso-038153	Fusarium solani	46.35	0.00e+00	1120.00
IUUC-Gmo-039602	Gadus morhua	50.52	0.00e+00	1233.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.20	0.00e+00	958.00
IUUC-Gga-040590	Gallus gallus	54.45	0.00e+00	1369.00
IUUC-Gac-041318	Gasterosteus aculeatus	53.86	0.00e+00	1353.00
IUUC-Gma-043585	Glycine max	82.52	0.00e+00	2085.00
IUUC-Ggo-045029	Gorilla gorilla	55.03	0.00e+00	1369.00
IUUC-Hsa-046078	Homo sapiens	55.03	0.00e+00	1368.00
IUUC-Hvu-047556	Hordeum vulgare	77.22	0.00e+00	2016.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	46.81	0.00e+00	767.00
IUUC-Kpa-049256	Komagataella pastoris	45.43	0.00e+00	1059.00
IUUC-Lch-049706	Latimeria chalumnae	53.99	0.00e+00	1350.00
IUUC-Lpe-051316	Leersia perrieri	84.89	0.00e+00	1528.00
IUUC-Loc-051867	Lepisosteus oculatus	49.89	0.00e+00	815.00
IUUC-Lma-053138	Leptosphaeria maculans	46.80	0.00e+00	1123.00
IUUC-Laf-053510	Loxodonta africana	55.36	0.00e+00	1392.00
IUUC-Mcc-055836	Macaca mulatta	54.46	0.00e+00	1368.00
IUUC-Meu-056238	Macropus eugenii	56.72	0.00e+00	773.00
IUUC-Mor-057172	Magnaporthe oryzae	45.82	0.00e+00	1101.00
IUUC-Mpo-057300	Magnaporthe poae	45.91	0.00e+00	1104.00
IUUC-Mtr-058248	Medicago truncatula	81.64	0.00e+00	2091.00
IUUC-Mla-059019	Melampsora laricipopulina	50.12	0.00e+00	1230.00
IUUC-Mga-059499	Meleagris gallopavo	54.36	0.00e+00	1365.00
IUUC-Mvi-060336	Microbotryum violaceum	50.77	0.00e+00	1213.00
IUUC-Mmr-061102	Microcebus murinus	54.95	0.00e+00	1353.00
IUUC-Mdo-062594	Monodelphis domestica	55.31	0.00e+00	1404.00
IUUC-Mmu-063736	Mus musculus	55.11	0.00e+00	1368.00
IUUC-Mac-065398	Musa acuminata	72.56	0.00e+00	1837.00
IUUC-Mpu-066701	Mustela putorius furo	54.66	0.00e+00	1368.00
IUUC-Mlu-067392	Myotis lucifugus	55.33	0.00e+00	1360.00
IUUC-Nfi-068270	Neosartorya fischeri	54.82	0.00e+00	967.00
IUUC-Ncr-068892	Neurospora crassa	47.24	0.00e+00	1117.00
IUUC-Nle-069634	Nomascus leucogenys	66.07	0.00e+00	946.00
IUUC-Opr-070952	Ochotona princeps	42.87	0.00e+00	669.00
IUUC-Ont-072488	Oreochromis niloticus	53.92	0.00e+00	1335.00
IUUC-Ocu-074211	Oryctolagus cuniculus	55.51	0.00e+00	1375.00
IUUC-Oba-074992	Oryza barthii	83.29	0.00e+00	1414.00
IUUC-Ogl-077364	Oryza glaberrima	84.64	0.00e+00	1527.00
IUUC-Ogu-078257	Oryza glumaepatula	84.52	0.00e+00	1524.00
IUUC-Oin-079274	Oryza indica	84.52	0.00e+00	1526.00
IUUC-Ome-081993	Oryza meridionalis	83.95	0.00e+00	1383.00
IUUC-Oni-082874	Oryza nivara	84.52	0.00e+00	1524.00
IUUC-Opu-083885	Oryza punctata	76.44	0.00e+00	2001.00
IUUC-Oru-084274	Oryza rufipogon	84.52	0.00e+00	1526.00
IUUC-Osa-085565	Oryza sativa	84.52	0.00e+00	1526.00
IUUC-Ola-086921	Oryzias latipes	54.46	0.00e+00	1337.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.96	0.00e+00	1578.00
IUUC-Oga-087991	Otolemur garnettii	52.25	0.00e+00	1273.00
IUUC-Oar-089590	Ovis aries	55.35	0.00e+00	1372.00
IUUC-Ptr-090808	Pan troglodytes	55.11	0.00e+00	1371.00
IUUC-Pan-092475	Papio anubis	55.31	0.00e+00	1371.00
IUUC-Psi-093044	Pelodiscus sinensis	48.18	0.00e+00	985.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.68	0.00e+00	1051.00
IUUC-Ppa-095785	Physcomitrella patens	70.48	0.00e+00	1808.00
IUUC-Pfo-097493	Poecilia formosa	53.75	0.00e+00	1332.00
IUUC-Pab-098497	Pongo abelii	55.43	0.00e+00	1379.00
IUUC-Pop-099992	Populus trichocarpa	85.41	0.00e+00	2108.00
IUUC-Pca-100413	Procavia capensis	60.61	0.00e+00	694.00
IUUC-Ppe-101899	Prunus persica	83.36	0.00e+00	2100.00
IUUC-Pva-102126	Pteropus vampyrus	53.13	0.00e+00	1296.00
IUUC-Pgr-103376	Puccinia graminis	50.04	0.00e+00	1238.00
IUUC-Ptt-103978	Puccinia triticina	53.79	0.00e+00	807.00
IUUC-Pte-104126	Pyrenophora teres	46.24	0.00e+00	1066.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	39.49	0.00e+00	729.00
IUUC-Rno-105428	Rattus norvegicus	55.43	0.00e+00	1373.00
IUUC-Sce-106464	Saccharomyces cerevisiae	42.85	0.00e+00	962.00
IUUC-Sha-107301	Sarcophilus harrisii	54.27	0.00e+00	1357.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.21	0.00e+00	1072.00
IUUC-Spo-108217	Schizosaccharomyces pombe	44.93	0.00e+00	1059.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	46.68	0.00e+00	1123.00
IUUC-Smo-109582	Selaginella moellendorffii	75.50	0.00e+00	1396.00
IUUC-Sly-111759	Solanum lycopersicum	83.20	0.00e+00	2120.00
IUUC-Stu-112564	Solanum tuberosum	82.95	0.00e+00	2113.00
IUUC-Sar-113313	Sorex araneus	45.84	2.00e-178	619.00
IUUC-Sbi-114388	Sorghum bicolor	85.25	0.00e+00	1531.00
IUUC-Sre-115209	Sporisorium reilianum	53.78	0.00e+00	1006.00
IUUC-Ssc-115933	Sus scrofa	55.43	0.00e+00	1375.00
IUUC-Tgu-117109	Taeniopygia guttata	42.50	1.00e-107	383.00
IUUC-Tru-117772	Takifugu rubripes	52.73	0.00e+00	1304.00
IUUC-Tsy-119105	Tarsius syrichta	52.48	0.00e+00	1045.00
IUUC-Tca-120918	Theobroma cacao	89.09	0.00e+00	1593.00
IUUC-Tre-121951	Trichoderma reesei	45.60	0.00e+00	1094.00
IUUC-Tvi-122359	Trichoderma virens	46.34	0.00e+00	1122.00
IUUC-Tae-125527	Triticum aestivum	76.52	0.00e+00	1976.00
IUUC-Tur-126754	Triticum urartu	75.88	0.00e+00	1931.00
IUUC-Tme-127170	Tuber melanosporum	48.45	0.00e+00	1186.00
IUUC-Tbe-127882	Tupaia belangeri	69.35	2.00e-129	456.00
IUUC-Ttr-128217	Tursiops truncatus	53.19	0.00e+00	1299.00
IUUC-Uma-129337	Ustilago maydis	54.28	0.00e+00	1010.00
IUUC-Vda-129828	Verticillium dahliae	46.02	0.00e+00	1105.00
IUUC-Vpa-130537	Vicugna pacos	54.90	0.00e+00	1348.00
IUUC-Vvi-130958	Vitis vinifera	82.54	0.00e+00	2105.00
IUUC-Xtr-132857	Xenopus tropicalis	53.34	0.00e+00	1296.00
IUUC-Xma-133138	Xiphophorus maculatus	53.67	0.00e+00	1332.00
IUUC-Yli-134399	Yarrowia lipolytica	48.78	0.00e+00	842.00
IUUC-Zma-135612	Zea mays	76.70	0.00e+00	1987.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence