iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mla-059019

Ensembl Protein ID

EGG11928

UniProt Accession

F4R6T0; F4R6T0_MELLP

Genbank Protein ID

EGG11928.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

GL883091

Gene Name

MELLADRAFT_73930

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MELLADRAFT_73930	EGG11928	EGG11928

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-41	136.7	135	167
UBD/Beta-Prp	7.60e-78	261.4	3	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           gH+  +   +f   d+++vs+s D t++vWD++
   Q: 135  GHNHYIMYAEFhpKDDYIVSCSMDQTVRVWDIT 167
           788888888999555****************75 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           + t +++++++++ ++f+p+ +lla++  +g+i+ w++++g+l++++ +h+++v+ + f+p+++++v+g++D+ ikvw+++++ c+ tl+gh d+v+s+sf
   Q: 3    MLTKFESKSNRVKGIAFHPKLTLLAASLHSGSIQMWNFQMGTLVERFDEHDGPVRGIAFHPSQPLFVSGGDDYKIKVWNYKQRRCLFTLHGHLDYVRSVSF 103
           67889999********************************************************************************************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkll 172
           +++  +++s+s+d+tir+w+++++qc+  +l+gh++ ++++++hp+++++vs+s D+tvr+Wd+                               +t+ ++
   Q: 104  HREHPWILSASDDQTIRIWNWQSRQCIA-ILTGHNHYIMYAEFHPKDDYIVSCSMDQTVRVWDItglrkktttaqpmsfedqvqransgqadlfgNTDAVV 203
           ****************************.*****************************************************************9888888 PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           +   +gh++ v++ +f+++ + +vs+++d+++klw +++++   v+t++gh +n++ v f+p++e+++s s+D++ir+Wd+ +++ ++t+ ++n++++  +
   Q: 204  KYVLEGHDRGVNWATFHPTLPLIVSCGDDRQIKLWRMSETKAweVDTCRGHFNNISAVLFHPKHELIISDSEDKTIRVWDMSKRTAVQTFRRENDRFWVLT 304
           888777********************************888778********************************************************* PP
   S: 272  vlsfgdnvlvlgsedskvniwklkkne 298
           + +++ n +++g  d  + ++kl++++
   Q: 305  A-HPELNLFAAG-HDTGLIVFKLDRER 329
           9.6666666655.46788888988776 PP

Organism

Melampsora laricipopulina

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MQMLTKFESK SNRVKGIAFH PKLTLLAASL HSGSIQMWNF QMGTLVERFD EHDGPVRGIA 60
FHPSQPLFVS GGDDYKIKVW NYKQRRCLFT LHGHLDYVRS VSFHREHPWI LSASDDQTIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGATGC TCACAAAGGT AAGCAACTTC ACCCGTCTCA GCAGATGTCT CTATTGCCAT 60
ACAATCCATT TATTCACAAT CTTGTTTTTA GTTTGAGTCC AAGTCCAATA GGGTCAAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

mlr:MELLADRAFT_73930

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	57.35	0.00e+00	1037.00
IUUC-Aml-001758	Ailuropoda melanoleuca	51.21	0.00e+00	1303.00
IUUC-Atr-002493	Amborella trichopoda	58.63	0.00e+00	1043.00
IUUC-Apl-003385	Anas platyrhynchos	49.58	0.00e+00	1032.00
IUUC-Aca-005154	Anolis carolinensis	67.96	2.00e-85	306.00
IUUC-Aly-006020	Arabidopsis lyrata	57.78	0.00e+00	1036.00
IUUC-Ath-007058	Arabidopsis thaliana	57.78	0.00e+00	1036.00
IUUC-Ago-007992	Ashbya gossypii	46.67	0.00e+00	1065.00
IUUC-Acl-008027	Aspergillus clavatus	63.87	0.00e+00	1155.00
IUUC-Afl-008644	Aspergillus flavus	64.39	0.00e+00	1151.00
IUUC-Afu-008964	Aspergillus fumigatus	56.84	0.00e+00	1437.00
IUUC-Ani-009379	Aspergillus nidulans	64.83	0.00e+00	1170.00
IUUC-Ang-009756	Aspergillus niger	56.67	0.00e+00	1432.00
IUUC-Aor-010174	Aspergillus oryzae	64.39	0.00e+00	1151.00
IUUC-Ate-010302	Aspergillus terreus	57.51	0.00e+00	1461.00
IUUC-Ame-011229	Astyanax mexicanus	57.64	0.00e+00	1043.00
IUUC-Bgr-012300	Blumeria graminis	56.17	0.00e+00	1369.00
IUUC-Bta-012524	Bos taurus	51.50	0.00e+00	1295.00
IUUC-Bci-013781	Botrytis cinerea	63.35	0.00e+00	1160.00
IUUC-Bdi-014549	Brachypodium distachyon	48.90	0.00e+00	1218.00
IUUC-Bol-015967	Brassica oleracea	51.57	0.00e+00	1142.00
IUUC-Bra-016978	Brassica rapa	57.35	0.00e+00	1029.00
IUUC-Cel-018115	Caenorhabditis elegans	53.05	0.00e+00	929.00
IUUC-Cja-019107	Callithrix jacchus	51.40	0.00e+00	1291.00
IUUC-Cfa-020675	Canis familiaris	50.99	0.00e+00	1282.00
IUUC-Cpo-021813	Cavia porcellus	51.73	0.00e+00	1317.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	58.79	0.00e+00	1057.00
IUUC-Csa-023523	Chlorocebus sabaeus	52.42	0.00e+00	1315.00
IUUC-Cho-024704	Choloepus hoffmanni	46.17	0.00e+00	1019.00
IUUC-Cin-025572	Ciona intestinalis	56.62	0.00e+00	1008.00
IUUC-Csv-025864	Ciona savignyi	55.36	0.00e+00	962.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	64.42	0.00e+00	1174.00
IUUC-Cne-027053	Cryptococcus neoformans	64.71	0.00e+00	1604.00
IUUC-Cme-027222	Cyanidioschyzon merolae	41.41	2.00e-144	504.00
IUUC-Dre-027421	Danio rerio	51.44	0.00e+00	1278.00
IUUC-Dno-029303	Dasypus novemcinctus	51.45	0.00e+00	1313.00
IUUC-Dor-030290	Dipodomys ordii	47.71	3.00e-152	530.00
IUUC-Dse-031543	Dothistroma septosporum	55.05	0.00e+00	1313.00
IUUC-Dme-031945	Drosophila melanogaster	56.74	0.00e+00	997.00
IUUC-Ete-032873	Echinops telfairi	56.04	0.00e+00	985.00
IUUC-Eca-033773	Equus caballus	50.79	0.00e+00	1271.00
IUUC-Eeu-034874	Erinaceus europaeus	41.97	0.00e+00	667.00
IUUC-Fca-035739	Felis catus	51.26	0.00e+00	1291.00
IUUC-Fal-037263	Ficedula albicollis	48.82	0.00e+00	1171.00
IUUC-Fox-037738	Fusarium oxysporum	56.51	0.00e+00	1437.00
IUUC-Fso-038153	Fusarium solani	56.39	0.00e+00	1433.00
IUUC-Gmo-039602	Gadus morhua	48.26	0.00e+00	1165.00
IUUC-Ggr-039931	Gaeumannomyces graminis	64.35	0.00e+00	1161.00
IUUC-Gga-040590	Gallus gallus	52.55	0.00e+00	1311.00
IUUC-Gac-041318	Gasterosteus aculeatus	51.52	0.00e+00	1276.00
IUUC-Gma-043257	Glycine max	57.28	0.00e+00	1034.00
IUUC-Ggo-045029	Gorilla gorilla	52.12	0.00e+00	1306.00
IUUC-Hsa-046078	Homo sapiens	51.96	0.00e+00	1306.00
IUUC-Hvu-047556	Hordeum vulgare	48.93	0.00e+00	1226.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	44.37	0.00e+00	745.00
IUUC-Kpa-049256	Komagataella pastoris	49.60	0.00e+00	1211.00
IUUC-Lch-049706	Latimeria chalumnae	51.93	0.00e+00	1299.00
IUUC-Lpe-051316	Leersia perrieri	57.63	0.00e+00	1049.00
IUUC-Loc-051867	Lepisosteus oculatus	48.43	0.00e+00	775.00
IUUC-Lma-053138	Leptosphaeria maculans	62.53	0.00e+00	1154.00
IUUC-Laf-053510	Loxodonta africana	52.70	0.00e+00	1316.00
IUUC-Mcc-055836	Macaca mulatta	51.37	0.00e+00	1310.00
IUUC-Meu-056238	Macropus eugenii	54.87	0.00e+00	757.00
IUUC-Mor-057172	Magnaporthe oryzae	55.82	0.00e+00	1410.00
IUUC-Mpo-057300	Magnaporthe poae	63.27	0.00e+00	1167.00
IUUC-Mtr-058248	Medicago truncatula	51.65	0.00e+00	1258.00
IUUC-Mga-059499	Meleagris gallopavo	52.54	0.00e+00	1308.00
IUUC-Mvi-060336	Microbotryum violaceum	74.68	0.00e+00	1859.00
IUUC-Mmr-061102	Microcebus murinus	51.38	0.00e+00	1300.00
IUUC-Mdo-062594	Monodelphis domestica	52.54	0.00e+00	1317.00
IUUC-Mmu-063736	Mus musculus	51.21	0.00e+00	1305.00
IUUC-Mac-065272	Musa acuminata	46.42	0.00e+00	1106.00
IUUC-Mpu-066701	Mustela putorius furo	52.53	0.00e+00	1310.00
IUUC-Mlu-067392	Myotis lucifugus	52.70	0.00e+00	1308.00
IUUC-Nfi-068270	Neosartorya fischeri	64.62	0.00e+00	1166.00
IUUC-Ncr-068892	Neurospora crassa	56.39	0.00e+00	1405.00
IUUC-Nle-069634	Nomascus leucogenys	62.39	0.00e+00	905.00
IUUC-Opr-070952	Ochotona princeps	39.85	0.00e+00	628.00
IUUC-Ont-072488	Oreochromis niloticus	51.70	0.00e+00	1278.00
IUUC-Ocu-074211	Oryctolagus cuniculus	51.42	0.00e+00	1311.00
IUUC-Oba-075761	Oryza barthii	57.51	0.00e+00	1045.00
IUUC-Obr-076429	Oryza brachyantha	57.28	0.00e+00	1041.00
IUUC-Ogl-077364	Oryza glaberrima	57.51	0.00e+00	1046.00
IUUC-Ogu-078257	Oryza glumaepatula	57.43	0.00e+00	1041.00
IUUC-Oin-079274	Oryza indica	57.40	0.00e+00	1044.00
IUUC-Olo-080466	Oryza longistaminata	58.95	0.00e+00	1046.00
IUUC-Ome-081993	Oryza meridionalis	60.78	0.00e+00	1001.00
IUUC-Oni-082874	Oryza nivara	57.45	0.00e+00	1046.00
IUUC-Opu-083885	Oryza punctata	57.63	0.00e+00	1044.00
IUUC-Oru-084274	Oryza rufipogon	57.40	0.00e+00	1044.00
IUUC-Osa-085565	Oryza sativa	57.40	0.00e+00	1044.00
IUUC-Ola-086921	Oryzias latipes	50.75	0.00e+00	1271.00
IUUC-Olu-087639	Ostreococcus lucimarinus	52.05	0.00e+00	1268.00
IUUC-Oga-087991	Otolemur garnettii	49.25	0.00e+00	1226.00
IUUC-Oar-089590	Ovis aries	51.65	0.00e+00	1312.00
IUUC-Ptr-090808	Pan troglodytes	51.96	0.00e+00	1305.00
IUUC-Pan-092475	Papio anubis	52.14	0.00e+00	1304.00
IUUC-Psi-093044	Pelodiscus sinensis	53.36	0.00e+00	871.00
IUUC-Pno-094839	Phaeosphaeria nodorum	54.94	0.00e+00	1326.00
IUUC-Ppa-095254	Physcomitrella patens	60.57	0.00e+00	1090.00
IUUC-Pfo-097493	Poecilia formosa	51.70	0.00e+00	1286.00
IUUC-Pab-098497	Pongo abelii	52.34	0.00e+00	1314.00
IUUC-Pop-099992	Populus trichocarpa	58.51	0.00e+00	1045.00
IUUC-Pca-100413	Procavia capensis	55.38	0.00e+00	651.00
IUUC-Ppe-101392	Prunus persica	49.80	0.00e+00	1237.00
IUUC-Pva-102126	Pteropus vampyrus	49.92	0.00e+00	1240.00
IUUC-Pgr-103376	Puccinia graminis	87.00	0.00e+00	2216.00
IUUC-Ptt-103978	Puccinia triticina	78.66	0.00e+00	1940.00
IUUC-Pte-104126	Pyrenophora teres	62.05	0.00e+00	1115.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	53.68	0.00e+00	756.00
IUUC-Rno-105428	Rattus norvegicus	51.80	0.00e+00	1312.00
IUUC-Sce-106464	Saccharomyces cerevisiae	52.57	0.00e+00	908.00
IUUC-Sha-107301	Sarcophilus harrisii	52.32	0.00e+00	1292.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	51.21	0.00e+00	1273.00
IUUC-Spo-108217	Schizosaccharomyces pombe	52.75	0.00e+00	1314.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	55.61	0.00e+00	1414.00
IUUC-Smo-109582	Selaginella moellendorffii	59.43	0.00e+00	1076.00
IUUC-Sit-109697	Setaria italica	57.51	0.00e+00	1047.00
IUUC-Sly-111759	Solanum lycopersicum	57.03	0.00e+00	1061.00
IUUC-Stu-112564	Solanum tuberosum	57.19	0.00e+00	1062.00
IUUC-Sar-113313	Sorex araneus	41.06	0.00e+00	638.00
IUUC-Sbi-114388	Sorghum bicolor	57.40	0.00e+00	1047.00
IUUC-Sre-115209	Sporisorium reilianum	71.81	0.00e+00	1325.00
IUUC-Ssc-115933	Sus scrofa	51.57	0.00e+00	1313.00
IUUC-Tgu-117109	Taeniopygia guttata	43.49	2.00e-96	344.00
IUUC-Tru-117772	Takifugu rubripes	51.76	0.00e+00	1265.00
IUUC-Tsy-119105	Tarsius syrichta	49.90	0.00e+00	990.00
IUUC-Tni-120556	Tetraodon nigroviridis	38.42	0.00e+00	768.00
IUUC-Tca-121046	Theobroma cacao	49.96	0.00e+00	1228.00
IUUC-Tre-121951	Trichoderma reesei	62.90	0.00e+00	1167.00
IUUC-Tvi-122359	Trichoderma virens	55.69	0.00e+00	1410.00
IUUC-Tae-123688	Triticum aestivum	48.85	0.00e+00	1224.00
IUUC-Tur-126754	Triticum urartu	57.23	0.00e+00	1036.00
IUUC-Tme-127170	Tuber melanosporum	57.47	0.00e+00	1447.00
IUUC-Tbe-127882	Tupaia belangeri	60.90	1.00e-114	405.00
IUUC-Ttr-128217	Tursiops truncatus	49.57	0.00e+00	1240.00
IUUC-Uma-129337	Ustilago maydis	71.31	0.00e+00	1313.00
IUUC-Vda-129828	Verticillium dahliae	54.76	0.00e+00	1371.00
IUUC-Vpa-130537	Vicugna pacos	50.98	0.00e+00	1288.00
IUUC-Vvi-130958	Vitis vinifera	57.67	0.00e+00	1047.00
IUUC-Xtr-132857	Xenopus tropicalis	50.45	0.00e+00	1202.00
IUUC-Xma-133138	Xiphophorus maculatus	51.62	0.00e+00	1287.00
IUUC-Yli-134399	Yarrowia lipolytica	54.70	0.00e+00	948.00
IUUC-Zma-135612	Zea mays	49.36	0.00e+00	1212.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence