iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-123688

Ensembl Protein ID

TRIAE_CS42_4BL_TGACv1_321458_AA1060720.1

UniProt Accession

A0A1D5XKY8; A0A1D5XKY8_WHEAT

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_4BL_TGACv1_321458_AA1060720	TRIAE_CS42_4BL_TGACv1_321458_AA1060720.1	TRIAE_CS42_4BL_TGACv1_321458_AA1060720.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-38	131.4	50	86
UBD/Beta-Prp	4.10e-77	262.0	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhKTqPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********4459********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgse 72
           t +++++++++ ++f+p +++++++  +g ++ wd+++g+ll ++ +h+++v+ v f+++++++v+g++
   Q: 3    TKFETKSNRVKGLAFHPRRPWILASLHSGVVQMWDYRMGTLLDRFDEHDGPVRGVHFHKTQPLFVSGGD 71
           67889999************************************************************* PP
   S: 73   DrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvn 141
           D+ ikvw+++t  c+ tl+gh d++++++f+ +  ++vs+s+d+tirvw++++++c+  +l+gh++ v+
   Q: 72   DYKIKVWNYKTHRCLFTLHGHLDYIRTVQFHDEHPWIVSASDDQTIRVWNWQSRTCVA-VLTGHNHYVM 139
           **********************************************************.********** PP
   S: 142  cvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllrtl.......tg 177
           c+++hp+++l+vs+slD+tvr+Wd+                                           +
   Q: 140  CASFHPKEDLVVSASLDQTVRVWDIgalrkkssspaddimrltqmntdlfgG-------IdavvkyvLE 201
           **********************************999999666655555553.......0444444555 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDg 244
           gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+
   Q: 202  GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVLFHAKQDIIVSNSEDK 270
           5********************************777668****************************** PP
   S: 245  siriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           sir+Wd ++++ ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 271  SIRVWDATKRTGIQTFRREHDRFWVLAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************************.6666655555.689999999988765 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLAFHPR RPWILASLHS GVVQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
KTQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHDEHPWIVS ASDDQTIRVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGAAGTGTG TCATTTGTGT AAAAGTGCCA ATAAAATTTA TGGCTTTGGG GAGGGGAGGG 60
GGGGGAGTGT TTATTTATTT CTCCTACTCC TAGAAGACAA CTCAGGGGTA CAAGTAGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002493	Amborella trichopoda	80.07	0.00e+00	1988.00
IUUC-Apl-003385	Anas platyrhynchos	49.25	0.00e+00	1033.00
IUUC-Acl-008027	Aspergillus clavatus	55.78	0.00e+00	974.00
IUUC-Afl-008644	Aspergillus flavus	56.66	0.00e+00	979.00
IUUC-Ani-009379	Aspergillus nidulans	56.08	0.00e+00	983.00
IUUC-Aor-010174	Aspergillus oryzae	56.66	0.00e+00	979.00
IUUC-Ame-011229	Astyanax mexicanus	53.57	0.00e+00	1316.00
IUUC-Bdi-014214	Brachypodium distachyon	95.32	0.00e+00	2383.00
IUUC-Cho-024704	Choloepus hoffmanni	42.15	8.00e-171	595.00
IUUC-Cne-027053	Cryptococcus neoformans	50.65	0.00e+00	1174.00
IUUC-Dme-031945	Drosophila melanogaster	52.04	0.00e+00	1239.00
IUUC-Eeu-034874	Erinaceus europaeus	42.11	0.00e+00	659.00
IUUC-Fal-037263	Ficedula albicollis	51.06	0.00e+00	1200.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.83	0.00e+00	969.00
IUUC-Gga-040590	Gallus gallus	54.21	0.00e+00	1352.00
IUUC-Gac-041318	Gasterosteus aculeatus	53.90	0.00e+00	1336.00
IUUC-Hvu-047556	Hordeum vulgare	99.26	0.00e+00	2479.00
IUUC-Lch-049706	Latimeria chalumnae	54.36	0.00e+00	1341.00
IUUC-Laf-053510	Loxodonta africana	55.34	0.00e+00	1374.00
IUUC-Mla-059019	Melampsora laricipopulina	49.96	0.00e+00	1208.00
IUUC-Mga-059499	Meleagris gallopavo	54.13	0.00e+00	1347.00
IUUC-Mvi-060336	Microbotryum violaceum	50.00	0.00e+00	1209.00
IUUC-Mpu-066701	Mustela putorius furo	54.62	0.00e+00	1352.00
IUUC-Mlu-067392	Myotis lucifugus	55.21	0.00e+00	1347.00
IUUC-Nfi-068270	Neosartorya fischeri	56.37	0.00e+00	979.00
IUUC-Ont-072488	Oreochromis niloticus	53.77	0.00e+00	1331.00
IUUC-Ome-081668	Oryza meridionalis	82.77	0.00e+00	1865.00
IUUC-Smo-109582	Selaginella moellendorffii	66.39	0.00e+00	1714.00
IUUC-Tgu-117109	Taeniopygia guttata	50.51	4.00e-103	369.00
IUUC-Tni-120556	Tetraodon nigroviridis	41.77	0.00e+00	880.00
IUUC-Tca-121545	Theobroma cacao	78.44	0.00e+00	2009.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence