iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048800

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01094894

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004952.2	ENSSTOT00000004962.2	ENSSTOP00000004450.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-68	231.7	84	780

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 8    NtCYmNSvLQcLsnipelrellle...............kkkeklneenpkepkgellkslqklfeel........w.....kskkkav 68
             CY+NSv  + ++ip + +l                   +  +l++ ++k++ +el +sl +++  +        +     ++++ a+
   Q: 84   VVCYLNSVNKMEYFIPWINSLHRLfylifinrtlmqppkYFLVSLSQLKKKSQYQELFCSLLSVIMIIleqlqasfLlnpekYTDELAT 172
           579999988888887644433333445777777776666333333444444555555555555554443333444314555577788** PP
   S: 69   sprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk...............eknkpkeeeeeedkselsde............. 129
           +pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                                   e             
   Q: 173  QPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvaelstkV------------------Eekphqkvemsgis 243
           ***************************************443333322222222110..................12244456677888 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 244  smetdgmrnsedhkeklpkgngkrksdtefgntkkkvkvskehqsleenqrqtrskrkatgdtleippkmipkcvsenestrlsqrksr 332
           8889999********************************************************************************** PP
   S: 130  .............................................................................aeekkkkknk.. 139
                                                                                         ++         
   Q: 333  vkinwlksatkqpsilskfcslgkittnqgskgqskeneydleedlgkceidnttngcglespgnnvkpvnvnevksINKG-----Aeq 416
           *******************************************************************99988544333333.....356 PP
   S: 140  ...slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekc 211
              +l+++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c
   Q: 417  igfELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEenseispepktemkTLRWAISQFASVERIVGEDKYFCENC 505
           666*****************************************99998**************************************** PP
   S: 212  kkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGH 294
           ++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGH
   Q: 506  HHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGH 589
           *************************************************************99.....678****************** PP
   S: 295  Yvayvkn.................................................................................. 301
           Y+a vk                                                                                   
   Q: 590  YTASVKVtdlnsleldkgnfvvdqtceigkpepmneeeardavenyddeevlirvggntqpskvlnkknveaigllggqkskadyelyn 678
           ***************************************************************************************** PP
   S: 302  ............................................................ekgkWllfdDskVtevkeeevleetg... 327
                                                                        +gkWllfdDs+V++++e+++l++ +   
   Q: 679  ktsnpdkvastafaesrnsesnntngthesdrnkessdqtginisgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpst 767
           ************************9999999999999999999999988888888877766999*******************888*** PP
   S: 328  ...staYvlfYkr 337
              st+Y+lfYk+
   Q: 768  sptSTPYLLFYKK 780
           ***********97 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQENEEKAS EYRGSEMYHV 60
VGTEQSWWIK KGVFVFCGVQ KTTVVCYLNS VNKMEYFIPW INSLHRLFYL IFINRTLMQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGGTG TCATACCCAG TGAAAGTAAT GGGCTTTCAA GAGGTAGTCC ATCCAAGAAA 60
AACAGACTTT CTTTGAAATT TTTTCAGAAA AAGGAAACTA AGAGAGCCTT AGATTTCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	84.63	0.00e+00	1241.00
IUUC-Apl-004204	Anas platyrhynchos	65.33	0.00e+00	821.00
IUUC-Aca-004637	Anolis carolinensis	59.10	0.00e+00	807.00
IUUC-Ame-011718	Astyanax mexicanus	43.14	5.00e-150	524.00
IUUC-Bta-012552	Bos taurus	82.95	0.00e+00	1229.00
IUUC-Cja-019588	Callithrix jacchus	85.24	0.00e+00	1290.00
IUUC-Cfa-020211	Canis familiaris	85.62	0.00e+00	1268.00
IUUC-Cpo-021551	Cavia porcellus	75.70	0.00e+00	1102.00
IUUC-Csa-024186	Chlorocebus sabaeus	85.50	0.00e+00	1300.00
IUUC-Cho-024739	Choloepus hoffmanni	73.55	0.00e+00	637.00
IUUC-Dre-028184	Danio rerio	43.94	1.00e-144	506.00
IUUC-Dno-029669	Dasypus novemcinctus	81.37	0.00e+00	1216.00
IUUC-Dor-030168	Dipodomys ordii	77.76	0.00e+00	1088.00
IUUC-Dme-031732	Drosophila melanogaster	29.25	2.00e-18	87.80
IUUC-Ete-032825	Echinops telfairi	86.11	0.00e+00	951.00
IUUC-Eca-033595	Equus caballus	83.52	0.00e+00	1165.00
IUUC-Eeu-034877	Erinaceus europaeus	85.66	2.00e-112	399.00
IUUC-Fca-035381	Felis catus	80.63	0.00e+00	827.00
IUUC-Fal-037592	Ficedula albicollis	62.72	0.00e+00	830.00
IUUC-Gmo-039680	Gadus morhua	41.88	2.00e-130	459.00
IUUC-Gga-041196	Gallus gallus	65.71	0.00e+00	917.00
IUUC-Gac-042292	Gasterosteus aculeatus	44.66	8.00e-120	424.00
IUUC-Ggo-044671	Gorilla gorilla	85.37	0.00e+00	1293.00
IUUC-Hsa-047020	Homo sapiens	85.11	0.00e+00	1288.00
IUUC-Lch-050543	Latimeria chalumnae	52.85	7.00e-171	593.00
IUUC-Loc-052338	Lepisosteus oculatus	47.45	7.00e-168	583.00
IUUC-Laf-053707	Loxodonta africana	81.77	0.00e+00	1234.00
IUUC-Mcc-055885	Macaca mulatta	85.62	0.00e+00	1301.00
IUUC-Meu-056573	Macropus eugenii	63.53	0.00e+00	860.00
IUUC-Mga-059346	Meleagris gallopavo	65.57	0.00e+00	867.00
IUUC-Mmr-061612	Microcebus murinus	84.73	0.00e+00	1219.00
IUUC-Mdo-062887	Monodelphis domestica	65.22	0.00e+00	912.00
IUUC-Mmu-064044	Mus musculus	79.16	0.00e+00	1187.00
IUUC-Mpu-066847	Mustela putorius furo	85.37	0.00e+00	1251.00
IUUC-Mlu-067684	Myotis lucifugus	82.11	0.00e+00	1236.00
IUUC-Nle-070057	Nomascus leucogenys	85.37	0.00e+00	1296.00
IUUC-Opr-070463	Ochotona princeps	88.15	0.00e+00	1017.00
IUUC-Ont-071975	Oreochromis niloticus	46.53	2.00e-116	413.00
IUUC-Oan-073062	Ornithorhynchus anatinus	55.05	2.00e-28	117.00
IUUC-Ocu-074840	Oryctolagus cuniculus	83.59	0.00e+00	1254.00
IUUC-Ola-087088	Oryzias latipes	43.47	9.00e-151	527.00
IUUC-Oga-088472	Otolemur garnettii	83.46	0.00e+00	1246.00
IUUC-Oar-089498	Ovis aries	82.82	0.00e+00	1228.00
IUUC-Ptr-091395	Pan troglodytes	85.50	0.00e+00	1293.00
IUUC-Pan-092462	Papio anubis	85.62	0.00e+00	1301.00
IUUC-Psi-093583	Pelodiscus sinensis	70.55	0.00e+00	863.00
IUUC-Pfo-096314	Poecilia formosa	41.97	4.00e-136	478.00
IUUC-Pab-098568	Pongo abelii	85.88	0.00e+00	1302.00
IUUC-Pca-100948	Procavia capensis	73.43	0.00e+00	1076.00
IUUC-Pva-102853	Pteropus vampyrus	83.06	0.00e+00	1236.00
IUUC-Rno-105573	Rattus norvegicus	80.41	0.00e+00	1186.00
IUUC-Sha-107495	Sarcophilus harrisii	70.31	0.00e+00	849.00
IUUC-Sar-113545	Sorex araneus	68.31	0.00e+00	937.00
IUUC-Ssc-115962	Sus scrofa	84.07	0.00e+00	1269.00
IUUC-Tgu-116731	Taeniopygia guttata	63.36	0.00e+00	847.00
IUUC-Tru-117893	Takifugu rubripes	43.13	8.00e-134	471.00
IUUC-Tsy-119644	Tarsius syrichta	75.54	0.00e+00	1081.00
IUUC-Tni-119819	Tetraodon nigroviridis	40.94	7.00e-142	497.00
IUUC-Tbe-127272	Tupaia belangeri	78.74	0.00e+00	1071.00
IUUC-Ttr-128404	Tursiops truncatus	84.33	0.00e+00	1264.00
IUUC-Vpa-130205	Vicugna pacos	83.44	0.00e+00	1249.00
IUUC-Xtr-132613	Xenopus tropicalis	50.55	0.00e+00	640.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence