iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089498

Ensembl Protein ID

ENSOARP00000009880.1

UniProt Accession

W5PHG3; W5PHG3_SHEEP

Genbank Protein ID

ENSOARP00000009880

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01001963

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009203.1	ENSOART00000010023.1	ENSOARP00000009880.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-85	286.7	81	781

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDEANQKDKGnckedslasyELICSLQSLIISVeqlqasfLlnpek 169
           6************************************999999999999999999999*****99999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk................eknkpkeeeeeedkselsde..... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                 e++ +kee+++        +     
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvedlptkvEEEYQKEEMSD--------Nnsmem 250
           88888*****************************************55666777776655553333333333333........244445 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 251  dnmkhsedykeklpkgngkrksdaefgnmkkkvkiskehqsleenqrqtrskrkaagdtleippkiipkhisenenarpsqrkskvkin 339
           577************************************************************************************** PP
   S: 130  .......................................................................aeekkkkknk.....sli 142
                                                                                        +k+      +l+
   Q: 340  wlksaakqpsilskfcsmgkiatnqgskghckeneydleedlgkyendnttndcelespenndmpinevkpI-----NKGAeqigfELV 423
           ************************************************************999999554443.....444455555*** PP
   S: 143  sdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqea 217
           ++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++++ea
   Q: 424  EKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEenseispepktemkTLRWAISQFASVERIVGEDKYFCENCHHYTEA 512
           **************************************99998********************************************** PP
   S: 218  ekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvk 300
           e++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a vk
   Q: 513  ERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTASVK 596
           *******************************************************99.....678************************ PP
   S: 301  n........................................................................................ 301
                                                                                                    
   Q: 597  Vtdlnsleldkenfvidqmceigkpeplneeevrgavenydneevsirvsgnnqpskvlnkknveavgllggqkskadyelynkasnpd 685
           ***************************************************************************************** PP
   S: 302  ......................................................ekgkWllfdDskVtevkeeevleetg......sta 330
                                                                  +gkWllfdDs+V++++e+++l++ +      st+
   Q: 686  kvastalpenrnsetnntngthesdsnkessdqtginisgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstsptSTP 774
           ******************9999999999999999999999988888888877766999*******************888********* PP
   S: 331  YvlfYkr 337
           Y+lfYk+
   Q: 775  YLLFYKK 781
           *****97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQENEEKTS EYKGSEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNIISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATGACTGG TGATTACAAG ATCCCTGTAT AAGTTAATTC CTGTCAACTG CTTGGAATTT 60
GAGGAGAAAA TGCCTGGTGT CATACCTAGT GAAAGTAATG GGCTTTCAAG AGGTAGTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development

KEGG

oas:101107236

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	91.48	0.00e+00	1405.00
IUUC-Apl-004204	Anas platyrhynchos	71.87	0.00e+00	931.00
IUUC-Aca-004637	Anolis carolinensis	65.48	0.00e+00	927.00
IUUC-Ame-011718	Astyanax mexicanus	47.87	3.00e-173	602.00
IUUC-Bta-012552	Bos taurus	97.83	0.00e+00	1489.00
IUUC-Cja-019588	Callithrix jacchus	92.36	0.00e+00	1439.00
IUUC-Cfa-020211	Canis familiaris	91.85	0.00e+00	1418.00
IUUC-Cpo-021551	Cavia porcellus	83.38	0.00e+00	1267.00
IUUC-Csa-024186	Chlorocebus sabaeus	92.87	0.00e+00	1447.00
IUUC-Cho-024739	Choloepus hoffmanni	80.60	0.00e+00	722.00
IUUC-Dre-028184	Danio rerio	49.08	6.00e-176	610.00
IUUC-Dno-029669	Dasypus novemcinctus	88.56	0.00e+00	1364.00
IUUC-Dor-030168	Dipodomys ordii	84.14	0.00e+00	1214.00
IUUC-Dme-031732	Drosophila melanogaster	29.19	1.00e-18	89.00
IUUC-Ete-032825	Echinops telfairi	85.59	0.00e+00	948.00
IUUC-Eca-033595	Equus caballus	90.25	0.00e+00	1302.00
IUUC-Eeu-034877	Erinaceus europaeus	79.05	1.00e-156	546.00
IUUC-Fca-035381	Felis catus	90.76	0.00e+00	987.00
IUUC-Fal-037592	Ficedula albicollis	68.68	0.00e+00	953.00
IUUC-Gmo-039680	Gadus morhua	44.84	3.00e-153	535.00
IUUC-Gga-041196	Gallus gallus	72.00	0.00e+00	1055.00
IUUC-Gac-042292	Gasterosteus aculeatus	48.16	7.00e-143	501.00
IUUC-Ggo-044671	Gorilla gorilla	92.23	0.00e+00	1440.00
IUUC-Hsa-047020	Homo sapiens	92.10	0.00e+00	1432.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	82.44	0.00e+00	1229.00
IUUC-Lch-050543	Latimeria chalumnae	57.85	0.00e+00	695.00
IUUC-Loc-052338	Lepisosteus oculatus	52.04	0.00e+00	704.00
IUUC-Laf-053707	Loxodonta africana	88.72	0.00e+00	1375.00
IUUC-Mcc-055885	Macaca mulatta	92.74	0.00e+00	1448.00
IUUC-Meu-056573	Macropus eugenii	66.84	0.00e+00	963.00
IUUC-Mga-059346	Meleagris gallopavo	72.43	0.00e+00	1000.00
IUUC-Mmr-061612	Microcebus murinus	89.94	0.00e+00	1359.00
IUUC-Mdo-062887	Monodelphis domestica	72.60	0.00e+00	1050.00
IUUC-Mmu-064044	Mus musculus	85.88	0.00e+00	1328.00
IUUC-Mpu-066847	Mustela putorius furo	92.36	0.00e+00	1425.00
IUUC-Mlu-067684	Myotis lucifugus	90.09	0.00e+00	1390.00
IUUC-Nle-070057	Nomascus leucogenys	92.36	0.00e+00	1441.00
IUUC-Opr-070463	Ochotona princeps	82.02	0.00e+00	1216.00
IUUC-Ont-071975	Oreochromis niloticus	45.89	3.00e-153	535.00
IUUC-Oan-073062	Ornithorhynchus anatinus	85.71	5.00e-47	179.00
IUUC-Ocu-074840	Oryctolagus cuniculus	91.34	0.00e+00	1400.00
IUUC-Ola-087088	Oryzias latipes	46.86	1.00e-174	607.00
IUUC-Oga-088472	Otolemur garnettii	90.19	0.00e+00	1382.00
IUUC-Ptr-091395	Pan troglodytes	92.36	0.00e+00	1438.00
IUUC-Pan-092462	Papio anubis	92.87	0.00e+00	1449.00
IUUC-Psi-093583	Pelodiscus sinensis	70.40	0.00e+00	890.00
IUUC-Pma-094644	Petromyzon marinus	35.95	8.00e-28	116.00
IUUC-Pfo-096314	Poecilia formosa	47.36	3.00e-169	588.00
IUUC-Pab-098568	Pongo abelii	92.87	0.00e+00	1448.00
IUUC-Pca-100948	Procavia capensis	79.80	0.00e+00	1208.00
IUUC-Pva-102853	Pteropus vampyrus	91.93	0.00e+00	1421.00
IUUC-Rno-105573	Rattus norvegicus	86.11	0.00e+00	1310.00
IUUC-Sha-107495	Sarcophilus harrisii	72.21	0.00e+00	894.00
IUUC-Sar-113545	Sorex araneus	75.89	0.00e+00	1078.00
IUUC-Ssc-115962	Sus scrofa	93.53	0.00e+00	1454.00
IUUC-Tgu-116731	Taeniopygia guttata	69.37	0.00e+00	969.00
IUUC-Tru-117893	Takifugu rubripes	46.11	6.00e-158	551.00
IUUC-Tsy-119644	Tarsius syrichta	81.89	0.00e+00	1206.00
IUUC-Tni-119819	Tetraodon nigroviridis	45.83	7.00e-173	600.00
IUUC-Tbe-127272	Tupaia belangeri	86.69	0.00e+00	1217.00
IUUC-Ttr-128404	Tursiops truncatus	93.47	0.00e+00	1461.00
IUUC-Vpa-130205	Vicugna pacos	92.08	0.00e+00	1429.00
IUUC-Xtr-132613	Xenopus tropicalis	55.03	0.00e+00	733.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence