iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	18927152

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	3.80e-08	33.3	12	71
E3 activity/RING/RING	2.10e-08	34.6	18	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
           v ee++CpI  ++ ++Pv ++ + + + r++I kw+ +++  cPv+r+ l  + lvP   l
   Q: 12   VDEELICPICTDVLEEPVQSSeCEHAFCRACIDKWMIQKQI-CPVDRSGLLTSHLVPVSRL 71
           5689***************999*************999999.**************97543 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC + +++++ +  C H+f++ C+ kw        ++++CP++r
   Q: 18   CPICTDVLEEPVQSSECEHAFCRACIDKW------MIQKQICPVDR 57
           **********777888*************......889999**987 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGFDLNCIVG HVDEELICPI CTDVLEEPVQ SSECEHAFCR ACIDKWMIQK QICPVDRSGL 60
LTSHLVPVSR LMRNMLSRLK IKCTFSQSGC AQMLALEEFR THVAACEHNP KVVVECSKGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATGCCAG CTCGGACACA ACTCAGCGCC GACGTAAAAA CTAACTTTTT GATCGAAATA 60
TTGTAAAAAT CGAGTTTCGG ATATAGGTAT AAGTACATAT CGAACTCAGT GGTAAGTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008974--TRAF-like
IPR003613--Ubox_domain
IPR015036--USP8_interacting
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF08941--USP8_interact

SMART

SM00184--RING
SM00504--Ubox

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0031386--F:protein tag
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000209--P:protein polyubiquitination

KEGG

dme:Dmel_CG9014

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000744	Aegilops tauschii	29.08	9.00e-12	65.50
IUUC-Atr-002634	Amborella trichopoda	27.27	7.00e-11	63.20
IUUC-Acl-008349	Aspergillus clavatus	30.69	3.00e-08	52.40
IUUC-Afu-008782	Aspergillus fumigatus	29.70	3.00e-07	49.30
IUUC-Ani-009190	Aspergillus nidulans	28.78	4.00e-08	52.00
IUUC-Ang-009779	Aspergillus niger	29.41	2.00e-08	52.80
IUUC-Bdi-014617	Brachypodium distachyon	28.37	1.00e-10	62.00
IUUC-Bol-016391	Brassica oleracea	25.90	1.00e-06	47.40
IUUC-Cgl-026455	Colletotrichum gloeosporioides	31.68	3.00e-11	62.40
IUUC-Cne-026870	Cryptococcus neoformans	36.00	2.00e-18	86.70
IUUC-Dse-031478	Dothistroma septosporum	29.70	2.00e-08	53.10
IUUC-Fox-037935	Fusarium oxysporum	33.33	4.00e-12	65.50
IUUC-Gma-043859	Glycine max	27.08	5.00e-10	60.10
IUUC-Hvu-047095	Hordeum vulgare	28.37	2.00e-11	64.30
IUUC-Lpe-050771	Leersia perrieri	25.71	3.00e-09	57.00
IUUC-Lma-053014	Leptosphaeria maculans	32.31	1.00e-11	63.90
IUUC-Mtr-057807	Medicago truncatula	25.17	8.00e-10	59.30
IUUC-Mac-064547	Musa acuminata	25.87	4.00e-09	56.60
IUUC-Nfi-068307	Neosartorya fischeri	29.70	2.00e-07	49.70
IUUC-Ncr-068632	Neurospora crassa	35.11	3.00e-12	65.90
IUUC-Oba-075596	Oryza barthii	24.82	2.00e-08	54.70
IUUC-Ogl-077360	Oryza glaberrima	26.56	6.00e-08	52.00
IUUC-Ogu-078462	Oryza glumaepatula	24.82	2.00e-08	54.30
IUUC-Oin-079887	Oryza indica	23.40	6.00e-07	49.30
IUUC-Ome-082014	Oryza meridionalis	24.82	1.00e-08	55.10
IUUC-Oni-083105	Oryza nivara	24.82	2.00e-08	54.70
IUUC-Opu-083191	Oryza punctata	26.26	1.00e-06	48.10
IUUC-Oru-084831	Oryza rufipogon	24.82	2.00e-08	54.70
IUUC-Pno-094854	Phaeosphaeria nodorum	32.31	9.00e-11	60.80
IUUC-Pop-099390	Populus trichocarpa	26.90	3.00e-10	60.80
IUUC-Ppe-101708	Prunus persica	26.21	1.00e-09	58.90
IUUC-Pte-104279	Pyrenophora teres	37.39	2.00e-11	63.90
IUUC-Pyt-104429	Pyrenophora triticirepentis	37.39	5.00e-12	65.10
IUUC-Sit-110555	Setaria italica	26.24	1.00e-09	58.20
IUUC-Sly-111800	Solanum lycopersicum	27.66	3.00e-11	63.90
IUUC-Sbi-114841	Sorghum bicolor	27.14	1.00e-10	61.60
IUUC-Tca-121454	Theobroma cacao	27.59	1.00e-10	62.00
IUUC-Tae-123531	Triticum aestivum	29.08	8.00e-12	65.50
IUUC-Tur-126325	Triticum urartu	28.37	3.00e-11	63.50
IUUC-Uma-129620	Ustilago maydis	26.67	6.00e-10	58.50
IUUC-Vda-129938	Verticillium dahliae	35.04	1.00e-16	80.90
IUUC-Vvi-131592	Vitis vinifera	26.90	6.00e-08	53.10
IUUC-Yli-134356	Yarrowia lipolytica	32.61	1.00e-08	53.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence