iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-43	144.6	156	195
UBD/Beta-Prp	7.00e-56	189.6	65	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           +Ht+ ++c+ +  sd  +++Gs+D t+ +WD+ +g ll+s
   Q: 156  THTSYMSCCIYpnSDQQILTGSGDSTCALWDVESGQLLQS 195
           5*******999976699******************99986 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvn 141
            l+gh+a+v ++++spd+  ++++s+D+ + +wd  t    h+++  +  ++++++ psg++++ G+ d+ + v+ + +++++ +   t   h++  +
   Q: 65   VLKGHQAKVLCTDWSPDKRHIISSSQDGRLIIWDAFTTNKEHAVTMPTTWIMACAYAPSGNFVACGGLDNKVTVYPITSDEEMAAkkrTVGTHTSYMS 162
           489********************************************************************************999999999999999 PP
   S: 142  cvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderl 237
           c  ++ +++ + +Gs D+t+ lWd+++g+ll+ + g h ++v  +++ +n   + +vsgs+d+   +wd+++g++v++++gh++ v+sv+f+p ++ +
   Q: 163  CCIYPNSDQQILTGSGDSTCALWDVESGQLLQSFHG-HSGDVMAIDLAPNEtgNTFVSGSCDRMAFIWDMRSGHVVQSFEGHQSDVNSVKFHPCGDAI 259
           99999999***************************9.*********9999888********************************************* PP
   S: 238  vsgssDgsiriWdlrsgdllktlql 262
           ++gs+D s r++d+r +  + ++++
   Q: 260  ATGSDDSSCRLYDMRADREVAVFAK 284
           ****************998888876 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSEAAVPASN ANANATEKMA SLVREAENLK TKLEEERQKL NDVNLSNIAE RLEQIAYVNI 60
KPRKVLKGHQ AKVLCTDWSP DKRHIISSSQ DGRLIIWDAF TTNKEHAVTM PTTWIMACAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTCGGATT TTCGTATTCG AGTATACACT TTTTTTCGGA TTGATTTTTC GCTGTCCAAT 60
TGGAGAAGTT CGAACGGGAT AGGACACACA ATCCCCGAGA GATATCCATA GAAGCGCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005886--C:plasma membrane
GO:0007186--P:G-protein coupled receptor signaling pathway

KEGG

dme:Dmel_CG10763

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	65.38	3.00e-142	497.00
IUUC-Apl-003399	Anas platyrhynchos	68.49	4.00e-136	476.00
IUUC-Aca-004861	Anolis carolinensis	67.73	6.00e-149	519.00
IUUC-Ago-007831	Ashbya gossypii	36.73	3.00e-63	235.00
IUUC-Ame-011851	Astyanax mexicanus	67.06	6.00e-146	509.00
IUUC-Bta-012438	Bos taurus	68.31	3.00e-149	520.00
IUUC-Cel-018408	Caenorhabditis elegans	60.34	3.00e-140	490.00
IUUC-Cja-019086	Callithrix jacchus	68.42	4.00e-148	516.00
IUUC-Cfa-021255	Canis familiaris	68.32	2.00e-140	491.00
IUUC-Cpo-021398	Cavia porcellus	66.11	3.00e-148	516.00
IUUC-Csa-023776	Chlorocebus sabaeus	68.60	1.00e-149	521.00
IUUC-Cin-025305	Ciona intestinalis	51.47	2.00e-122	431.00
IUUC-Csv-026058	Ciona savignyi	52.28	2.00e-119	421.00
IUUC-Dre-028572	Danio rerio	64.79	1.00e-146	511.00
IUUC-Dor-031013	Dipodomys ordii	71.48	2.00e-115	407.00
IUUC-Eca-033977	Equus caballus	65.90	2.00e-144	504.00
IUUC-Eeu-035079	Erinaceus europaeus	68.02	7.00e-149	519.00
IUUC-Fca-035693	Felis catus	64.35	1.00e-139	488.00
IUUC-Fal-037345	Ficedula albicollis	68.02	8.00e-149	518.00
IUUC-Gmo-039222	Gadus morhua	68.52	9.00e-141	492.00
IUUC-Gga-040320	Gallus gallus	68.31	4.00e-149	520.00
IUUC-Gac-042644	Gasterosteus aculeatus	65.10	5.00e-147	512.00
IUUC-Ggo-044489	Gorilla gorilla	64.93	5.00e-139	486.00
IUUC-Hsa-046434	Homo sapiens	68.60	1.00e-149	521.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	64.87	7.00e-127	445.00
IUUC-Loc-052790	Lepisosteus oculatus	67.91	2.00e-139	488.00
IUUC-Laf-054255	Loxodonta africana	67.54	3.00e-147	513.00
IUUC-Mcc-055610	Macaca mulatta	68.42	3.00e-148	517.00
IUUC-Meu-056819	Macropus eugenii	66.24	2.00e-129	454.00
IUUC-Mga-059740	Meleagris gallopavo	68.47	4.00e-138	483.00
IUUC-Mmr-061221	Microcebus murinus	68.60	2.00e-149	521.00
IUUC-Mdo-062619	Monodelphis domestica	68.12	5.00e-150	523.00
IUUC-Mmu-064266	Mus musculus	68.90	9.00e-150	522.00
IUUC-Mpu-065766	Mustela putorius furo	70.43	3.00e-135	473.00
IUUC-Mlu-067221	Myotis lucifugus	62.57	6.00e-140	489.00
IUUC-Nle-069515	Nomascus leucogenys	68.79	4.00e-138	483.00
IUUC-Opr-070195	Ochotona princeps	62.21	5.00e-129	453.00
IUUC-Ont-071535	Oreochromis niloticus	64.89	1.00e-125	442.00
IUUC-Ocu-074666	Oryctolagus cuniculus	70.43	1.00e-135	474.00
IUUC-Ola-086578	Oryzias latipes	68.34	9.00e-139	485.00
IUUC-Oga-089090	Otolemur garnettii	68.21	7.00e-148	515.00
IUUC-Oar-090017	Ovis aries	64.39	2.00e-138	484.00
IUUC-Ptr-091280	Pan troglodytes	68.35	2.00e-138	484.00
IUUC-Pan-092198	Papio anubis	68.79	5.00e-138	483.00
IUUC-Psi-093030	Pelodiscus sinensis	65.56	2.00e-139	488.00
IUUC-Pfo-097182	Poecilia formosa	67.90	9.00e-141	492.00
IUUC-Pab-098157	Pongo abelii	68.60	4.00e-149	520.00
IUUC-Pva-102232	Pteropus vampyrus	61.00	1.00e-126	444.00
IUUC-Rno-105526	Rattus norvegicus	65.61	3.00e-138	483.00
IUUC-Sha-106754	Sarcophilus harrisii	68.44	3.00e-140	490.00
IUUC-Ssc-115390	Sus scrofa	68.41	7.00e-149	519.00
IUUC-Tgu-117377	Taeniopygia guttata	68.47	2.00e-136	478.00
IUUC-Tru-117938	Takifugu rubripes	68.12	4.00e-139	486.00
IUUC-Tsy-119392	Tarsius syrichta	58.82	1.00e-120	425.00
IUUC-Tni-119834	Tetraodon nigroviridis	62.62	2.00e-123	434.00
IUUC-Tbe-127469	Tupaia belangeri	66.57	4.00e-140	489.00
IUUC-Ttr-128252	Tursiops truncatus	68.31	1.00e-146	511.00
IUUC-Vpa-130173	Vicugna pacos	63.92	5.00e-99	353.00
IUUC-Xtr-131803	Xenopus tropicalis	68.44	3.00e-140	490.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence