iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000047799.2	ENSRNOT00000011963.6	ENSRNOP00000011963.6
ENSRNOG00000047799.2	ENSRNOT00000075708.2	ENSRNOP00000066690.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-36	122.9	238	274
UBD/Beta-Prp	1.20e-48	166.3	288	352

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +H+++v+++++ ++ + ++sGsdD t++++Dlr ++ 
   Q: 238  THESDVNSVRYyPSgDAFASGSDDATCRLYDLRADRE 274
           5*********99666*****************99875 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirv 120
           ++v+fs +g +l  g +D+ti+vwd+ +g+ v++l ghe++v +l++sp+g  + sGs+d t+rv
   Q: 288  SSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 352
           5899**********************************************************997 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MATDGLHENE TLASLKSEAE SLKGKLEEER AKLHDVELHQ VAERVEALGQ FVMKTRRTLK 60
GHGNKVLCMD WCKDKRRIVS SSQDGKVIVW DSFTTNKEHA VTMPCTWVMA CAYAPSGCAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAACCG ATGGGCTGCA CGAGAACGAG ACGCTGGCGT CGCTGAAGAG CGAGGCCGAG 60
AGCCTCAAGG GCAAGCTAGA GGAGGAGCGG GCGAAGCTGC ATGACGTGGA GCGTGAGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	88.45	0.00e+00	643.00
IUUC-Apl-003399	Anas platyrhynchos	94.32	2.00e-178	618.00
IUUC-Aca-004861	Anolis carolinensis	93.24	0.00e+00	683.00
IUUC-Ame-011851	Astyanax mexicanus	88.17	0.00e+00	652.00
IUUC-Bta-012438	Bos taurus	95.49	0.00e+00	695.00
IUUC-Cel-018408	Caenorhabditis elegans	61.92	1.00e-129	456.00
IUUC-Cja-019086	Callithrix jacchus	95.77	0.00e+00	696.00
IUUC-Cfa-021255	Canis familiaris	95.40	0.00e+00	644.00
IUUC-Cpo-021398	Cavia porcellus	93.82	0.00e+00	680.00
IUUC-Csa-023776	Chlorocebus sabaeus	95.49	0.00e+00	694.00
IUUC-Cin-025305	Ciona intestinalis	54.62	3.00e-120	424.00
IUUC-Csv-026058	Ciona savignyi	55.01	2.00e-118	418.00
IUUC-Dre-028572	Danio rerio	88.44	0.00e+00	642.00
IUUC-Dno-029958	Dasypus novemcinctus	80.16	3.00e-111	394.00
IUUC-Dor-031013	Dipodomys ordii	94.57	4.00e-142	497.00
IUUC-Dme-031889	Drosophila melanogaster	65.61	9.00e-138	483.00
IUUC-Eca-033977	Equus caballus	90.37	0.00e+00	648.00
IUUC-Eeu-035079	Erinaceus europaeus	95.21	0.00e+00	694.00
IUUC-Fca-035693	Felis catus	88.45	0.00e+00	638.00
IUUC-Fal-037345	Ficedula albicollis	94.37	0.00e+00	689.00
IUUC-Gmo-039222	Gadus morhua	87.32	2.00e-179	621.00
IUUC-Gga-040320	Gallus gallus	94.37	0.00e+00	691.00
IUUC-Gac-042644	Gasterosteus aculeatus	87.61	0.00e+00	649.00
IUUC-Ggo-044489	Gorilla gorilla	91.32	0.00e+00	653.00
IUUC-Hsa-046434	Homo sapiens	95.77	0.00e+00	696.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	89.38	4.00e-167	580.00
IUUC-Loc-052790	Lepisosteus oculatus	91.24	0.00e+00	641.00
IUUC-Laf-054255	Loxodonta africana	94.65	0.00e+00	687.00
IUUC-Mcc-055610	Macaca mulatta	95.49	0.00e+00	694.00
IUUC-Meu-056819	Macropus eugenii	92.41	3.00e-171	594.00
IUUC-Mga-059740	Meleagris gallopavo	87.36	0.00e+00	627.00
IUUC-Mmr-061221	Microcebus murinus	95.49	0.00e+00	694.00
IUUC-Mdo-062619	Monodelphis domestica	94.08	0.00e+00	687.00
IUUC-Mmu-064266	Mus musculus	96.34	0.00e+00	697.00
IUUC-Mpu-065766	Mustela putorius furo	94.72	4.00e-170	590.00
IUUC-Mlu-067221	Myotis lucifugus	87.61	0.00e+00	629.00
IUUC-Nle-069515	Nomascus leucogenys	95.28	9.00e-180	622.00
IUUC-Opr-070195	Ochotona princeps	86.48	1.00e-175	608.00
IUUC-Ont-071535	Oreochromis niloticus	78.87	4.00e-147	514.00
IUUC-Ocu-074666	Oryctolagus cuniculus	95.05	1.00e-170	591.00
IUUC-Ola-086578	Oryzias latipes	88.73	6.00e-178	616.00
IUUC-Oga-089090	Otolemur garnettii	95.24	0.00e+00	689.00
IUUC-Oar-090017	Ovis aries	89.77	0.00e+00	629.00
IUUC-Ptr-091280	Pan troglodytes	95.30	1.00e-180	625.00
IUUC-Pan-092198	Papio anubis	94.69	1.00e-179	622.00
IUUC-Psi-093030	Pelodiscus sinensis	86.20	0.00e+00	629.00
IUUC-Pma-094140	Petromyzon marinus	88.89	3.00e-89	320.00
IUUC-Pfo-097182	Poecilia formosa	88.45	0.00e+00	629.00
IUUC-Pab-098157	Pongo abelii	95.77	0.00e+00	696.00
IUUC-Pca-100988	Procavia capensis	75.00	9.00e-143	499.00
IUUC-Pva-102232	Pteropus vampyrus	83.05	1.00e-167	582.00
IUUC-Sha-106754	Sarcophilus harrisii	94.65	0.00e+00	644.00
IUUC-Ssc-115390	Sus scrofa	95.51	0.00e+00	692.00
IUUC-Tgu-117377	Taeniopygia guttata	94.34	6.00e-179	620.00
IUUC-Tru-117938	Takifugu rubripes	88.45	3.00e-178	617.00
IUUC-Tsy-119392	Tarsius syrichta	79.72	7.00e-157	546.00
IUUC-Tni-119834	Tetraodon nigroviridis	73.24	4.00e-142	497.00
IUUC-Tbe-127469	Tupaia belangeri	93.45	0.00e+00	662.00
IUUC-Ttr-128252	Tursiops truncatus	95.21	0.00e+00	685.00
IUUC-Vpa-130173	Vicugna pacos	86.15	4.00e-128	451.00
IUUC-Xtr-131803	Xenopus tropicalis	92.68	0.00e+00	640.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence