iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-12	46.3	49	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtc..lafsdtllvsGsdDgtikvWDlrtgvl 35
           s+t+  +++  + ++sG+ Dg i v+D+rt ++
   Q: 49   SITSlaVQW--PWVASGGTDGRIFVYDMRTRKQ 79
           678833477..89***************99776 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPPEMEIIEA TNEELLLGFK LIKSPTDGFT DSVKFELKQT FADSSYARSI TSLAVQWPWV 60
ASGGTDGRIF VYDMRTRKQS QIILSHAGRV NTLKFTPDLS LLLSGSDDGH MIATRVGSWT 120

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Nucleotide Sequence
(Fasta)

CTCCGCCTCT AACTTCGAAT AGTCCTTGCC GCTGGAACAC GTTTTGACAG CAGAAATAAA 60
TTCTTGAATA GAATTTAGTG ACTTATTCGA CAAATCCATT TAATTTTCCA TTTCCATTTT 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0008283--P:cell proliferation
GO:0042273--P:ribosomal large subunit biogenesis
GO:0006364--P:rRNA processing

KEGG

dme:Dmel_CG9123

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence