iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048348

Ensembl Protein ID

ENSSTOP00000001099.2

UniProt Accession

I3LY73; I3LY73_ICTTR

Genbank Protein ID

ENSSTOP00000001099

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01102981

Gene Name

KDM5C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000001217.2	ENSSTOT00000001227.2	ENSSTOP00000001099.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.50e-14	51.5	326	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vC +C +g+ed+ +l+ C+ C++++H  Cl ++  +e p+   w CpkC 
   Q: 326  VCRMCSRGDEDD-KLLLCDGCDDNYHIFCLLPP-LPEIPKGV-WRCPKCV 372
           8*********88.6*******************.*******8.******6 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MEPGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 60
DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERRIL DLYSLSKIVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGAGGGGA GGGGGAGACG CTGACAAACC AAGATGGCGG CGGCGGCGAT GGAGGCCGCG 60
GCGGTTGGGA GGTAACTGTA GTGGTGAGGG CTGTGTTAGT TAGGAGGCAG CGGCAGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0003677--F:DNA binding
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001327	Ailuropoda melanoleuca	97.87	0.00e+00	2677.00
IUUC-Apl-004141	Anas platyrhynchos	56.23	0.00e+00	1424.00
IUUC-Aca-004712	Anolis carolinensis	79.56	0.00e+00	2002.00
IUUC-Afl-008625	Aspergillus flavus	30.13	6.00e-112	399.00
IUUC-Afu-008796	Aspergillus fumigatus	31.36	1.00e-115	411.00
IUUC-Aor-010155	Aspergillus oryzae	30.13	7.00e-112	399.00
IUUC-Ate-010453	Aspergillus terreus	30.32	7.00e-109	389.00
IUUC-Bgr-012241	Blumeria graminis	29.52	1.00e-110	395.00
IUUC-Bta-013099	Bos taurus	97.71	0.00e+00	2617.00
IUUC-Bci-013992	Botrytis cinerea	29.93	2.00e-108	387.00
IUUC-Cja-018723	Callithrix jacchus	94.27	0.00e+00	2572.00
IUUC-Cfa-020954	Canis familiaris	97.92	0.00e+00	2610.00
IUUC-Cpo-021718	Cavia porcellus	97.96	0.00e+00	1373.00
IUUC-Csa-023946	Chlorocebus sabaeus	97.50	0.00e+00	2602.00
IUUC-Cho-024280	Choloepus hoffmanni	53.71	0.00e+00	1310.00
IUUC-Cin-025321	Ciona intestinalis	47.26	0.00e+00	1008.00
IUUC-Csv-026185	Ciona savignyi	44.87	0.00e+00	1131.00
IUUC-Dre-028238	Danio rerio	63.25	0.00e+00	1862.00
IUUC-Dno-029435	Dasypus novemcinctus	94.61	0.00e+00	2614.00
IUUC-Dor-030226	Dipodomys ordii	90.29	0.00e+00	1801.00
IUUC-Dse-031479	Dothistroma septosporum	29.56	9.00e-119	422.00
IUUC-Dme-032021	Drosophila melanogaster	46.37	0.00e+00	1105.00
IUUC-Eca-033834	Equus caballus	96.84	0.00e+00	2706.00
IUUC-Eeu-034692	Erinaceus europaeus	95.20	0.00e+00	2030.00
IUUC-Fca-035766	Felis catus	94.83	0.00e+00	2513.00
IUUC-Fal-037078	Ficedula albicollis	56.13	0.00e+00	1442.00
IUUC-Fox-037694	Fusarium oxysporum	31.87	5.00e-100	359.00
IUUC-Fso-038127	Fusarium solani	30.67	2.00e-115	410.00
IUUC-Gmo-039140	Gadus morhua	70.88	0.00e+00	1686.00
IUUC-Gac-041825	Gasterosteus aculeatus	64.37	0.00e+00	1785.00
IUUC-Ggo-045492	Gorilla gorilla	97.87	0.00e+00	2710.00
IUUC-Hsa-046737	Homo sapiens	97.81	0.00e+00	2692.00
IUUC-Lch-050517	Latimeria chalumnae	75.21	0.00e+00	2109.00
IUUC-Laf-054098	Loxodonta africana	88.85	0.00e+00	2371.00
IUUC-Mcc-055740	Macaca mulatta	97.61	0.00e+00	2702.00
IUUC-Meu-056643	Macropus eugenii	84.57	0.00e+00	2269.00
IUUC-Mor-057198	Magnaporthe oryzae	29.51	6.00e-116	412.00
IUUC-Mtr-058113	Medicago truncatula	32.66	2.00e-96	348.00
IUUC-Mmr-061032	Microcebus murinus	98.04	0.00e+00	2612.00
IUUC-Mdo-062754	Monodelphis domestica	81.15	0.00e+00	2197.00
IUUC-Mmu-063943	Mus musculus	95.42	0.00e+00	2692.00
IUUC-Mpu-066800	Mustela putorius furo	97.16	0.00e+00	2678.00
IUUC-Mlu-067109	Myotis lucifugus	96.12	0.00e+00	2638.00
IUUC-Nfi-068430	Neosartorya fischeri	30.39	5.00e-149	522.00
IUUC-Ncr-068763	Neurospora crassa	29.42	3.00e-111	397.00
IUUC-Nle-069569	Nomascus leucogenys	98.62	0.00e+00	2587.00
IUUC-Ont-072274	Oreochromis niloticus	65.53	0.00e+00	1841.00
IUUC-Oan-073160	Ornithorhynchus anatinus	85.86	0.00e+00	2280.00
IUUC-Ocu-074440	Oryctolagus cuniculus	97.94	0.00e+00	2675.00
IUUC-Oin-079273	Oryza indica	37.84	9.00e-14	69.30
IUUC-Opu-083164	Oryza punctata	30.48	2.00e-88	321.00
IUUC-Ola-087059	Oryzias latipes	66.11	0.00e+00	1875.00
IUUC-Oga-088191	Otolemur garnettii	97.28	0.00e+00	2691.00
IUUC-Oar-090027	Ovis aries	97.64	0.00e+00	2616.00
IUUC-Ptr-091415	Pan troglodytes	84.24	0.00e+00	2370.00
IUUC-Pan-091829	Papio anubis	97.16	0.00e+00	2689.00
IUUC-Psi-093550	Pelodiscus sinensis	56.40	0.00e+00	1412.00
IUUC-Pma-094137	Petromyzon marinus	56.30	0.00e+00	1290.00
IUUC-Pno-094879	Phaeosphaeria nodorum	29.80	3.00e-114	406.00
IUUC-Pfo-096645	Poecilia formosa	65.24	0.00e+00	1800.00
IUUC-Pab-097582	Pongo abelii	95.21	0.00e+00	2356.00
IUUC-Pca-100446	Procavia capensis	93.62	0.00e+00	2619.00
IUUC-Ppe-101504	Prunus persica	32.56	6.00e-103	369.00
IUUC-Pva-102553	Pteropus vampyrus	94.28	0.00e+00	1640.00
IUUC-Pgr-103434	Puccinia graminis	35.98	2.00e-29	123.00
IUUC-Pte-104195	Pyrenophora teres	30.60	3.00e-113	403.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	29.48	6.00e-114	405.00
IUUC-Rno-105359	Rattus norvegicus	80.44	0.00e+00	2338.00
IUUC-Sha-106769	Sarcophilus harrisii	88.13	0.00e+00	2135.00
IUUC-Sja-107970	Schizosaccharomyces japonicus	21.67	7.00e-41	162.00
IUUC-Spo-108283	Schizosaccharomyces pombe	22.50	4.00e-48	187.00
IUUC-Ssl-108489	Sclerotinia sclerotiorum	30.62	2.00e-118	421.00
IUUC-Sar-113052	Sorex araneus	55.56	0.00e+00	1434.00
IUUC-Sre-115161	Sporisorium reilianum	30.42	2.00e-132	468.00
IUUC-Ssc-116354	Sus scrofa	97.94	0.00e+00	2743.00
IUUC-Tgu-116613	Taeniopygia guttata	57.00	0.00e+00	1445.00
IUUC-Tru-117667	Takifugu rubripes	65.53	0.00e+00	1663.00
IUUC-Tni-119920	Tetraodon nigroviridis	64.68	0.00e+00	1798.00
IUUC-Tca-121478	Theobroma cacao	32.43	4.00e-107	383.00
IUUC-Tre-122213	Trichoderma reesei	29.13	5.00e-110	392.00
IUUC-Tvi-122263	Trichoderma virens	28.57	2.00e-104	374.00
IUUC-Tme-127087	Tuber melanosporum	31.56	6.00e-126	446.00
IUUC-Tbe-128040	Tupaia belangeri	99.46	0.00e+00	1088.00
IUUC-Ttr-128979	Tursiops truncatus	97.74	0.00e+00	2694.00
IUUC-Uma-129590	Ustilago maydis	29.54	5.00e-130	459.00
IUUC-Vpa-130433	Vicugna pacos	98.94	0.00e+00	1808.00
IUUC-Vvi-131071	Vitis vinifera	32.27	1.00e-85	311.00
IUUC-Xtr-132324	Xenopus tropicalis	68.54	0.00e+00	1911.00
IUUC-Xma-134315	Xiphophorus maculatus	65.06	0.00e+00	1863.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence