iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068393

Ensembl Protein ID

CADNFIAP00005158

UniProt Accession

A1DL56; A1DL56_NEOFI

Genbank Protein ID

EAW15527.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

DS027698

Gene Name

NFIA_048640

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00005286	CADNFIAT00005286	CADNFIAP00005158

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-58	196.3	110	564
ULD/UDP/UBQ/UBQ_Other	8.80e-11	40.6	8	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.......kkkeklneenp.............kepkgellkslqklfeelwkskkkavsprell 74
           Gl+NlgNtCY+NS+LQ+L ++pel++ ll+                +               + + +l++sl++lf+++ +++++ + p ++l
   Q: 110  GLQNLGNTCYLNSTLQTLRSVPELQQELLNyrpsagsL--------AGsrlsdlsslglggLGASMDLVSSLRDLFKQM-SETQEGFPPLMFL 193
           9*****************************54333331........22234555555555567777*************.99999******** PP
   S: 75   kalkkeaeefs.......gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikc.... 156
           +al+++ ++f        gy+qqDa+E +++++ ql+++l       + +            + e +   + s++++ + g+++s + c    
   Q: 194  NALRSIFPQFAqkdrngqGYAQQDAEEAWSQIVTQLRSKL-------VIK------------EGEGDSATEVSFVDKYLAGRFESVTECddpa 267
           **********999***************************.......111............2345677889*****************4444 PP
   S: 157  ..lecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
              + ++ +++ + f++l +++ ++++     l+d + +   ee++e+     +++ +++   +k+ ++ +lP++L++h+ Rf +++e++++ 
   Q: 268  arAAGEEATKSSDIFYKLDCHIGKETN----HLHDGILAG-LEEKIEK----RSPTLDRDAVYTKRSRIARLPKYLTVHFVRFFWKRETQKKA 351
           322345556888889999999999996....577766333.3567774....7899999999******************************* PP
   S: 248  kinkkvefpleLdlspfcts................................................................peekqke.. 274
           ki +kv+fp eLd+ +fct+                                                                      +  
   Q: 352  KIMRKVTFPAELDVVEFCTEelkkqlipirdkvrdirkeevdverarkrqklahqreeelkraaesdaglepmqkkqvtegqkeA-----Tks 439
           ********************77777777777777777777777777777777777776666666666666666666555555550.....055 PP
   S: 275  ..................................................kkkYeLiavvvHsG.slssGHYvayvkn.......ekgkWllf 309
                                                             +  YeL av+ H+G s++sGHY++yvk+       e+gkW+ f
   Q: 440  geqdgdtamtdvfksdaeyeaeknasilaakkelatlidpklasdagtnkSGLYELRAVITHQGaSADSGHYTSYVKKqpngkgeEDGKWWWF 532
           55555555666666666666666666666666666666666666667666****************************88887777888**** PP
   S: 310  dDskVtevkeeevleetg....staYvlfYkr 337
           +D+kVtev+ e++++  g    ++a +l+Y+ 
   Q: 533  NDEKVTEVDGEKIETLAGggesHSALILLYRA 564
           ***************8889***********85 PP

ULD/UDP/UBQ/UBQ_Other

   S: 8    ldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekksg 75
            +g++++++++ps++  +LK ++++++g+ pe+q++++kG  L++  +L+++++k+g+t++++ + sg
   Q: 8    HQGKRHEVELDPSANGETLKYQMYSLTGVEPERQKILVKGGQLKNETPLSALNAKPGQTFMMMGTPSG 75
           47889**********************************************************99876 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MFSVIVKHQG KRHEVELDPS ANGETLKYQM YSLTGVEPER QKILVKGGQL KNETPLSALN 60
AKPGQTFMMM GTPSGGQDAV DLGRPKEPVK FLEDMTEAEA ARAEGATPAG LQNLGNTCYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCTCAG TTATCGTGAA GCACCAAGGC AAACGTCATG AGGTCGAGCT CGATCCATCT 60
GCGAATGGCG AAACACTGAA ATATCAGATG TACTCCTTGA CTGGAGTCGA ACCCGAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005838--C:proteasome regulatory particle
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nfi:NFIA_048640

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	27.61	9.00e-29	119.00
IUUC-Aml-002053	Ailuropoda melanoleuca	37.41	5.00e-65	240.00
IUUC-Atr-002725	Amborella trichopoda	36.00	2.00e-74	271.00
IUUC-Apl-004031	Anas platyrhynchos	34.66	6.00e-76	276.00
IUUC-Aca-004361	Anolis carolinensis	35.74	8.00e-86	309.00
IUUC-Aly-006176	Arabidopsis lyrata	37.10	5.00e-83	300.00
IUUC-Ath-007658	Arabidopsis thaliana	36.46	1.00e-84	305.00
IUUC-Ago-007796	Ashbya gossypii	32.98	4.00e-80	290.00
IUUC-Acl-008258	Aspergillus clavatus	90.32	0.00e+00	934.00
IUUC-Afl-008732	Aspergillus flavus	85.89	0.00e+00	950.00
IUUC-Afu-008755	Aspergillus fumigatus	97.20	0.00e+00	1037.00
IUUC-Ani-009148	Aspergillus nidulans	80.14	0.00e+00	862.00
IUUC-Ang-009878	Aspergillus niger	84.48	0.00e+00	906.00
IUUC-Aor-010239	Aspergillus oryzae	85.71	0.00e+00	947.00
IUUC-Ate-010243	Aspergillus terreus	84.30	0.00e+00	913.00
IUUC-Ame-011327	Astyanax mexicanus	40.38	8.00e-16	76.60
IUUC-Bgr-012231	Blumeria graminis	63.76	0.00e+00	700.00
IUUC-Bta-012553	Bos taurus	38.14	7.00e-67	246.00
IUUC-Bci-013606	Botrytis cinerea	65.80	0.00e+00	693.00
IUUC-Bdi-014567	Brachypodium distachyon	39.02	1.00e-79	288.00
IUUC-Bol-015565	Brassica oleracea	40.04	3.00e-89	320.00
IUUC-Bra-017297	Brassica rapa	39.68	6.00e-88	316.00
IUUC-Cel-018140	Caenorhabditis elegans	30.53	3.00e-60	224.00
IUUC-Cja-019516	Callithrix jacchus	38.20	2.00e-66	244.00
IUUC-Cfa-020808	Canis familiaris	37.74	2.00e-67	248.00
IUUC-Cpo-021688	Cavia porcellus	37.32	1.00e-65	242.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	33.42	3.00e-47	181.00
IUUC-Csa-023429	Chlorocebus sabaeus	36.85	2.00e-64	237.00
IUUC-Cho-024347	Choloepus hoffmanni	37.50	6.00e-66	243.00
IUUC-Cin-025198	Ciona intestinalis	37.69	5.00e-53	200.00
IUUC-Csv-026007	Ciona savignyi	36.29	7.00e-56	209.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	60.00	5.00e-170	589.00
IUUC-Cne-026963	Cryptococcus neoformans	35.99	5.00e-78	283.00
IUUC-Cme-027240	Cyanidioschyzon merolae	35.49	4.00e-51	194.00
IUUC-Dre-027647	Danio rerio	34.32	4.00e-77	280.00
IUUC-Dno-029967	Dasypus novemcinctus	37.09	2.00e-64	238.00
IUUC-Dor-030886	Dipodomys ordii	33.51	4.00e-42	164.00
IUUC-Dse-031466	Dothistroma septosporum	55.41	3.00e-155	540.00
IUUC-Dme-032079	Drosophila melanogaster	37.07	8.00e-61	226.00
IUUC-Ete-032351	Echinops telfairi	33.92	5.00e-71	259.00
IUUC-Eca-033461	Equus caballus	38.21	3.00e-71	260.00
IUUC-Eeu-035220	Erinaceus europaeus	33.04	4.00e-38	150.00
IUUC-Fca-036210	Felis catus	37.50	3.00e-67	247.00
IUUC-Fal-037528	Ficedula albicollis	35.47	7.00e-75	273.00
IUUC-Fox-037805	Fusarium oxysporum	61.83	0.00e+00	655.00
IUUC-Fso-038177	Fusarium solani	58.55	0.00e+00	644.00
IUUC-Gmo-038953	Gadus morhua	38.31	3.00e-68	250.00
IUUC-Ggr-039972	Gaeumannomyces graminis	59.79	2.00e-177	613.00
IUUC-Gga-040462	Gallus gallus	37.32	5.00e-64	236.00
IUUC-Gac-041312	Gasterosteus aculeatus	34.84	2.00e-79	288.00
IUUC-Gma-043255	Glycine max	37.28	1.00e-81	295.00
IUUC-Ggo-045458	Gorilla gorilla	33.50	2.00e-43	168.00
IUUC-Hsa-045706	Homo sapiens	36.85	2.00e-64	238.00
IUUC-Hvu-047821	Hordeum vulgare	41.47	1.00e-36	144.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	38.14	6.00e-68	249.00
IUUC-Lch-050464	Latimeria chalumnae	34.61	3.00e-78	283.00
IUUC-Lpe-051419	Leersia perrieri	37.45	5.00e-79	286.00
IUUC-Loc-052732	Lepisosteus oculatus	38.04	2.00e-68	251.00
IUUC-Lma-053177	Leptosphaeria maculans	63.78	0.00e+00	653.00
IUUC-Laf-053822	Loxodonta africana	37.26	1.00e-66	245.00
IUUC-Mcc-055893	Macaca mulatta	36.85	2.00e-64	238.00
IUUC-Meu-056307	Macropus eugenii	36.93	8.00e-61	226.00
IUUC-Mor-057171	Magnaporthe oryzae	56.85	0.00e+00	628.00
IUUC-Mpo-057415	Magnaporthe poae	58.23	5.00e-178	615.00
IUUC-Mtr-057901	Medicago truncatula	37.32	4.00e-82	296.00
IUUC-Mla-058897	Melampsora laricipopulina	36.92	2.00e-93	334.00
IUUC-Mga-060016	Meleagris gallopavo	37.35	2.00e-64	237.00
IUUC-Mvi-060562	Microbotryum violaceum	39.29	1.00e-88	318.00
IUUC-Mmr-060624	Microcebus murinus	38.44	9.00e-72	262.00
IUUC-Mdo-061809	Monodelphis domestica	35.22	6.00e-76	276.00
IUUC-Mmu-063869	Mus musculus	38.14	1.00e-65	241.00
IUUC-Mac-064876	Musa acuminata	34.73	2.00e-64	238.00
IUUC-Mpu-066480	Mustela putorius furo	37.97	4.00e-68	250.00
IUUC-Mlu-067866	Myotis lucifugus	38.68	2.00e-68	251.00
IUUC-Ncr-068815	Neurospora crassa	60.55	0.00e+00	625.00
IUUC-Nle-070121	Nomascus leucogenys	41.35	1.00e-37	147.00
IUUC-Opr-070712	Ochotona princeps	33.19	4.00e-32	130.00
IUUC-Ont-071544	Oreochromis niloticus	39.70	2.00e-65	241.00
IUUC-Oan-073635	Ornithorhynchus anatinus	36.69	1.00e-51	195.00
IUUC-Ocu-074926	Oryctolagus cuniculus	37.18	3.00e-64	237.00
IUUC-Oba-075633	Oryza barthii	42.74	3.00e-67	247.00
IUUC-Obr-076423	Oryza brachyantha	36.99	2.00e-75	275.00
IUUC-Ogl-077913	Oryza glaberrima	38.18	8.00e-79	285.00
IUUC-Ogu-078435	Oryza glumaepatula	42.74	3.00e-67	247.00
IUUC-Oin-080072	Oryza indica	42.74	4.00e-67	247.00
IUUC-Olo-080535	Oryza longistaminata	33.28	9.00e-66	242.00
IUUC-Ome-081309	Oryza meridionalis	42.74	3.00e-67	247.00
IUUC-Oni-083113	Oryza nivara	42.74	3.00e-67	247.00
IUUC-Opu-083168	Oryza punctata	41.94	2.00e-63	234.00
IUUC-Oru-084253	Oryza rufipogon	42.74	3.00e-67	247.00
IUUC-Osa-085554	Oryza sativa	37.64	1.00e-76	278.00
IUUC-Ola-086998	Oryzias latipes	39.20	2.00e-65	241.00
IUUC-Olu-087818	Ostreococcus lucimarinus	32.93	3.00e-60	224.00
IUUC-Oga-088571	Otolemur garnettii	37.03	8.00e-66	242.00
IUUC-Oar-089526	Ovis aries	38.14	7.00e-67	246.00
IUUC-Ptr-091433	Pan troglodytes	36.85	2.00e-64	238.00
IUUC-Pan-091966	Papio anubis	36.85	2.00e-64	237.00
IUUC-Psi-093458	Pelodiscus sinensis	36.10	7.00e-80	289.00
IUUC-Pma-094343	Petromyzon marinus	34.43	2.00e-40	157.00
IUUC-Pno-095109	Phaeosphaeria nodorum	63.40	0.00e+00	662.00
IUUC-Ppa-095756	Physcomitrella patens	37.23	1.00e-90	325.00
IUUC-Pfo-096514	Poecilia formosa	38.69	4.00e-65	240.00
IUUC-Pab-098477	Pongo abelii	33.58	1.00e-51	195.00
IUUC-Pop-099221	Populus trichocarpa	36.87	6.00e-80	289.00
IUUC-Pca-100791	Procavia capensis	30.06	1.00e-27	115.00
IUUC-Ppe-101812	Prunus persica	36.91	5.00e-82	296.00
IUUC-Pva-102462	Pteropus vampyrus	35.83	2.00e-53	201.00
IUUC-Pgr-103623	Puccinia graminis	42.39	5.00e-73	266.00
IUUC-Ptt-103767	Puccinia triticina	41.95	8.00e-70	256.00
IUUC-Pte-104109	Pyrenophora teres	66.09	0.00e+00	687.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	65.06	0.00e+00	671.00
IUUC-Rno-105351	Rattus norvegicus	37.16	3.00e-63	234.00
IUUC-Sce-106168	Saccharomyces cerevisiae	34.15	3.00e-79	287.00
IUUC-Sha-107491	Sarcophilus harrisii	35.22	1.00e-80	291.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	38.35	7.00e-99	352.00
IUUC-Spo-108174	Schizosaccharomyces pombe	39.86	6.00e-104	369.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	65.80	0.00e+00	675.00
IUUC-Smo-108805	Selaginella moellendorffii	42.86	3.00e-75	273.00
IUUC-Sit-110361	Setaria italica	37.39	1.00e-75	275.00
IUUC-Sly-110965	Solanum lycopersicum	37.46	1.00e-83	302.00
IUUC-Sar-113355	Sorex araneus	37.39	9.00e-53	199.00
IUUC-Sbi-114778	Sorghum bicolor	37.57	2.00e-75	274.00
IUUC-Sre-115011	Sporisorium reilianum	44.03	5.00e-80	290.00
IUUC-Ssc-116273	Sus scrofa	37.50	6.00e-65	239.00
IUUC-Tgu-117063	Taeniopygia guttata	35.58	2.00e-74	271.00
IUUC-Tru-118381	Takifugu rubripes	35.95	2.00e-66	244.00
IUUC-Tsy-119076	Tarsius syrichta	46.34	9.00e-17	79.70
IUUC-Tni-119941	Tetraodon nigroviridis	38.69	6.00e-67	246.00
IUUC-Tca-121246	Theobroma cacao	37.70	3.00e-82	297.00
IUUC-Tre-121969	Trichoderma reesei	58.93	5.00e-170	589.00
IUUC-Tvi-122543	Trichoderma virens	58.23	7.00e-178	615.00
IUUC-Tae-125744	Triticum aestivum	38.76	2.00e-83	301.00
IUUC-Tur-126128	Triticum urartu	43.23	2.00e-19	88.20
IUUC-Tbe-128030	Tupaia belangeri	36.11	8.00e-42	162.00
IUUC-Ttr-128701	Tursiops truncatus	37.54	2.00e-50	191.00
IUUC-Uma-129657	Ustilago maydis	39.51	2.00e-95	341.00
IUUC-Vda-129723	Verticillium dahliae	58.73	0.00e+00	644.00
IUUC-Vpa-130284	Vicugna pacos	33.17	8.00e-26	109.00
IUUC-Vvi-131037	Vitis vinifera	37.30	6.00e-85	306.00
IUUC-Xtr-132235	Xenopus tropicalis	39.16	7.00e-71	259.00
IUUC-Xma-133840	Xiphophorus maculatus	38.69	3.00e-65	240.00
IUUC-Yli-134453	Yarrowia lipolytica	44.01	1.00e-116	411.00
IUUC-Zma-135791	Zea mays	36.63	3.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence