iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.20e-06	27.7	44	107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 7    lCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
           +C I++ + + P +   G +++ ++I k+l++ +  +P+t+q++++++lv  +++r+  +++++ 
   Q: 44   HCCITMAPYEMPYCDLQGNVFEYEAILKFLKTFKV-NPITGQKMDSKSLVKLNFHRNANDEYHCP 107
           699*************************9988887.*************************9986 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGKRQHQKDK MYLTYTEWSE LYGGKKVESL ENDHVKFKRL PFEHCCITMA PYEMPYCDLQ 60
GNVFEYEAIL KFLKTFKVNP ITGQKMDSKS LVKLNFHRNA NDEYHCPALF KPFSKNSHIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCACAGAG TTGGCAGTTC TCTCCCGCAT TTGTAAACAA ACTATTTGTA GCTCTTACTT 60
TATTGCAAAT TTAATTTAAA AAAACAAACA GCCAAGATGG GTAAAAGGCA GCATCAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0413--Isomerase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0697--Rotamase

Interpro

IPR029000--Cyclophilin-like_dom
IPR024936--Cyclophilin-type_PPIase
IPR020892--Cyclophilin-type_PPIase_CS
IPR002130--Cyclophilin-type_PPIase_dom
IPR027799--Rtf2_RING-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00170--CSA_PPIASE_1
PS50072--CSA_PPIASE_2

Pfam

PF00160--Pro_isomerase
PF04641--Rtf2

PRINTS

PR00153--CSAPPISMRASE

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005634--C:nucleus
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000398--P:mRNA splicing, via spliceosome
GO:0006457--P:protein folding
GO:0000209--P:protein polyubiquitination

KEGG

dme:Dmel_CG7747

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000982	Aegilops tauschii	59.02	1.00e-55	209.00
IUUC-Aml-002351	Ailuropoda melanoleuca	50.54	6.00e-159	553.00
IUUC-Atr-002724	Amborella trichopoda	48.80	5.00e-60	224.00
IUUC-Apl-003515	Anas platyrhynchos	54.33	3.00e-136	478.00
IUUC-Aca-004802	Anolis carolinensis	55.32	5.00e-160	556.00
IUUC-Aly-005928	Arabidopsis lyrata	44.01	5.00e-104	370.00
IUUC-Ath-007574	Arabidopsis thaliana	43.61	1.00e-99	356.00
IUUC-Acl-008183	Aspergillus clavatus	39.72	1.00e-93	336.00
IUUC-Afl-008382	Aspergillus flavus	40.12	1.00e-101	362.00
IUUC-Afu-008952	Aspergillus fumigatus	40.00	1.00e-94	339.00
IUUC-Ani-009146	Aspergillus nidulans	40.33	5.00e-98	350.00
IUUC-Ang-009743	Aspergillus niger	39.17	1.00e-99	356.00
IUUC-Aor-010027	Aspergillus oryzae	39.67	5.00e-100	357.00
IUUC-Ate-010569	Aspergillus terreus	38.64	2.00e-91	328.00
IUUC-Ame-010783	Astyanax mexicanus	55.14	1.00e-160	558.00
IUUC-Bgr-012172	Blumeria graminis	36.64	7.00e-76	277.00
IUUC-Bta-012459	Bos taurus	50.98	9.00e-153	532.00
IUUC-Bci-013693	Botrytis cinerea	42.67	7.00e-107	380.00
IUUC-Bdi-014623	Brachypodium distachyon	59.80	1.00e-61	229.00
IUUC-Bol-015781	Brassica oleracea	60.50	8.00e-61	227.00
IUUC-Bra-016624	Brassica rapa	43.22	4.00e-106	377.00
IUUC-Cel-018328	Caenorhabditis elegans	46.30	2.00e-129	454.00
IUUC-Cja-019427	Callithrix jacchus	53.24	1.00e-157	548.00
IUUC-Cfa-020829	Canis familiaris	54.36	4.00e-161	560.00
IUUC-Cpo-022189	Cavia porcellus	53.44	1.00e-158	551.00
IUUC-Cre-022723	Chlamydomonas reinhardtii	57.28	5.00e-62	231.00
IUUC-Csa-024212	Chlorocebus sabaeus	52.44	2.00e-152	531.00
IUUC-Cin-025720	Ciona intestinalis	52.59	8.00e-152	529.00
IUUC-Csv-026137	Ciona savignyi	52.01	3.00e-144	504.00
IUUC-Cgl-026532	Colletotrichum gloeosporioides	41.32	7.00e-102	363.00
IUUC-Cne-026830	Cryptococcus neoformans	38.24	1.00e-94	339.00
IUUC-Dre-028561	Danio rerio	55.01	1.00e-157	548.00
IUUC-Dno-029029	Dasypus novemcinctus	48.57	2.00e-142	498.00
IUUC-Dor-030683	Dipodomys ordii	59.20	5.00e-50	191.00
IUUC-Dse-031506	Dothistroma septosporum	40.41	3.00e-104	371.00
IUUC-Ete-033157	Echinops telfairi	44.23	6.00e-110	390.00
IUUC-Eeu-034470	Erinaceus europaeus	50.13	4.00e-103	367.00
IUUC-Fca-036571	Felis catus	53.38	1.00e-153	535.00
IUUC-Fal-037613	Ficedula albicollis	52.42	2.00e-146	511.00
IUUC-Fox-037795	Fusarium oxysporum	36.18	4.00e-99	354.00
IUUC-Fso-038213	Fusarium solani	38.80	8.00e-93	333.00
IUUC-Gmo-039609	Gadus morhua	51.98	2.00e-141	494.00
IUUC-Ggr-039825	Gaeumannomyces graminis	41.09	5.00e-102	364.00
IUUC-Gga-041191	Gallus gallus	53.04	2.00e-153	534.00
IUUC-Gac-041524	Gasterosteus aculeatus	52.61	5.00e-150	523.00
IUUC-Gma-042925	Glycine max	55.90	8.00e-57	214.00
IUUC-Ggo-045352	Gorilla gorilla	53.44	1.00e-158	551.00
IUUC-Hsa-045709	Homo sapiens	53.44	2.00e-158	551.00
IUUC-Hvu-047058	Hordeum vulgare	59.31	6.00e-61	228.00
IUUC-Itr-048483	Ictidomys tridecemlineatus	56.03	6.00e-149	519.00
IUUC-Lch-049681	Latimeria chalumnae	55.01	1.00e-144	505.00
IUUC-Lpe-050799	Leersia perrieri	60.00	7.00e-62	231.00
IUUC-Loc-052566	Lepisosteus oculatus	43.80	9.00e-119	419.00
IUUC-Lma-053028	Leptosphaeria maculans	41.92	2.00e-98	352.00
IUUC-Laf-054547	Loxodonta africana	53.32	4.00e-158	550.00
IUUC-Mcc-054753	Macaca mulatta	53.20	2.00e-156	545.00
IUUC-Meu-056855	Macropus eugenii	43.31	2.00e-70	258.00
IUUC-Mor-056941	Magnaporthe oryzae	38.94	9.00e-95	340.00
IUUC-Mpo-057306	Magnaporthe poae	38.39	7.00e-105	373.00
IUUC-Mtr-058349	Medicago truncatula	59.22	2.00e-55	209.00
IUUC-Mla-058842	Melampsora laricipopulina	40.98	4.00e-97	347.00
IUUC-Mga-060099	Meleagris gallopavo	49.13	3.00e-132	464.00
IUUC-Mvi-060413	Microbotryum violaceum	38.54	3.00e-95	342.00
IUUC-Mmr-061530	Microcebus murinus	53.42	9.00e-160	555.00
IUUC-Mdo-062668	Monodelphis domestica	58.22	5.00e-153	533.00
IUUC-Mmu-063871	Mus musculus	53.23	2.00e-158	551.00
IUUC-Mac-064559	Musa acuminata	59.22	1.00e-61	229.00
IUUC-Mpu-065919	Mustela putorius furo	54.17	4.00e-158	550.00
IUUC-Mlu-067846	Myotis lucifugus	46.76	6.00e-140	490.00
IUUC-Nfi-068507	Neosartorya fischeri	40.29	4.00e-96	344.00
IUUC-Ncr-068805	Neurospora crassa	42.01	3.00e-88	318.00
IUUC-Nle-070125	Nomascus leucogenys	50.67	4.00e-146	510.00
IUUC-Opr-070486	Ochotona princeps	55.92	2.00e-130	457.00
IUUC-Ont-071597	Oreochromis niloticus	53.88	7.00e-156	542.00
IUUC-Oan-073439	Ornithorhynchus anatinus	63.49	7.00e-21	90.90
IUUC-Ocu-074411	Oryctolagus cuniculus	53.04	4.00e-155	540.00
IUUC-Oba-075040	Oryza barthii	60.49	5.00e-62	231.00
IUUC-Obr-076727	Oryza brachyantha	60.98	3.00e-62	232.00
IUUC-Ogl-077605	Oryza glaberrima	60.49	5.00e-62	231.00
IUUC-Ogu-078177	Oryza glumaepatula	60.49	5.00e-62	231.00
IUUC-Oin-079549	Oryza indica	58.05	1.00e-55	210.00
IUUC-Olo-081090	Oryza longistaminata	60.49	4.00e-62	231.00
IUUC-Ome-081979	Oryza meridionalis	60.49	5.00e-62	231.00
IUUC-Oni-082819	Oryza nivara	60.49	5.00e-62	231.00
IUUC-Opu-083212	Oryza punctata	60.98	7.00e-61	227.00
IUUC-Oru-084412	Oryza rufipogon	60.49	5.00e-62	231.00
IUUC-Osa-085431	Oryza sativa	44.36	5.00e-33	132.00
IUUC-Ola-086602	Oryzias latipes	51.96	5.00e-131	460.00
IUUC-Olu-087682	Ostreococcus lucimarinus	40.82	1.00e-88	319.00
IUUC-Oga-088999	Otolemur garnettii	48.57	5.00e-146	510.00
IUUC-Oar-089338	Ovis aries	47.05	9.00e-116	409.00
IUUC-Ptr-091185	Pan troglodytes	53.44	1.00e-158	551.00
IUUC-Pan-092321	Papio anubis	53.63	2.00e-160	557.00
IUUC-Psi-094018	Pelodiscus sinensis	58.70	1.00e-86	311.00
IUUC-Pma-094111	Petromyzon marinus	51.01	3.00e-106	377.00
IUUC-Pno-094782	Phaeosphaeria nodorum	43.35	1.00e-100	359.00
IUUC-Ppa-095335	Physcomitrella patens	47.76	3.00e-62	231.00
IUUC-Pfo-097393	Poecilia formosa	55.09	2.00e-158	551.00
IUUC-Pab-098263	Pongo abelii	50.19	2.00e-143	501.00
IUUC-Pop-099316	Populus trichocarpa	48.97	4.00e-108	384.00
IUUC-Pca-100387	Procavia capensis	45.91	4.00e-48	184.00
IUUC-Ppe-101275	Prunus persica	60.50	1.00e-55	210.00
IUUC-Pva-102150	Pteropus vampyrus	53.32	6.00e-125	439.00
IUUC-Pgr-103378	Puccinia graminis	42.76	1.00e-104	372.00
IUUC-Ptt-103908	Puccinia triticina	40.58	1.00e-92	332.00
IUUC-Pte-104248	Pyrenophora teres	42.95	5.00e-101	360.00
IUUC-Pyt-104645	Pyrenophora triticirepentis	41.41	1.00e-101	362.00
IUUC-Rno-105162	Rattus norvegicus	53.33	4.00e-158	550.00
IUUC-Sha-107123	Sarcophilus harrisii	58.56	1.00e-74	273.00
IUUC-Sja-107828	Schizosaccharomyces japonicus	39.87	2.00e-87	315.00
IUUC-Spo-108368	Schizosaccharomyces pombe	37.45	2.00e-96	345.00
IUUC-Smo-109263	Selaginella moellendorffii	41.78	2.00e-108	385.00
IUUC-Sit-110821	Setaria italica	60.49	5.00e-62	231.00
IUUC-Sly-111803	Solanum lycopersicum	40.73	6.00e-112	397.00
IUUC-Stu-112730	Solanum tuberosum	43.41	2.00e-110	392.00
IUUC-Sar-113618	Sorex araneus	54.08	2.00e-147	514.00
IUUC-Sbi-114487	Sorghum bicolor	59.51	8.00e-61	227.00
IUUC-Sre-115009	Sporisorium reilianum	36.16	2.00e-77	282.00
IUUC-Ssc-115984	Sus scrofa	53.99	5.00e-156	543.00
IUUC-Tgu-117410	Taeniopygia guttata	53.61	3.00e-153	533.00
IUUC-Tru-118537	Takifugu rubripes	52.51	1.00e-150	525.00
IUUC-Tsy-119318	Tarsius syrichta	39.40	7.00e-60	224.00
IUUC-Tni-120514	Tetraodon nigroviridis	53.86	6.00e-118	416.00
IUUC-Tca-121620	Theobroma cacao	58.33	6.00e-54	204.00
IUUC-Tre-121904	Trichoderma reesei	41.30	1.00e-80	293.00
IUUC-Tvi-122585	Trichoderma virens	41.44	2.00e-81	295.00
IUUC-Tae-125342	Triticum aestivum	59.31	7.00e-61	227.00
IUUC-Tme-126960	Tuber melanosporum	40.52	2.00e-117	415.00
IUUC-Tbe-127839	Tupaia belangeri	38.67	2.00e-46	178.00
IUUC-Ttr-129173	Tursiops truncatus	44.02	6.00e-115	407.00
IUUC-Uma-129595	Ustilago maydis	37.50	2.00e-75	276.00
IUUC-Vda-130012	Verticillium dahliae	42.48	8.00e-110	390.00
IUUC-Vvi-131156	Vitis vinifera	49.66	3.00e-61	228.00
IUUC-Xtr-132807	Xenopus tropicalis	51.08	2.00e-154	538.00
IUUC-Xma-133940	Xiphophorus maculatus	55.98	1.00e-44	171.00
IUUC-Yli-134361	Yarrowia lipolytica	31.51	8.00e-45	174.00
IUUC-Zma-135759	Zea mays	60.70	6.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence