iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-09	38.5	32	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC e f   d  ++++ CgHvfh+dCl +w       +++ +CP Cr
   Q: 32   CAICNEFFraNDIIFSTSrCGHVFHKDCLTRW------LNRSRTCPQCR 74
           ****888854332554445*************......**********8 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MESNSSEMEG NGGKIAETAP TNDSSPSLNI LCAICNEFFR ANDIIFSTSR CGHVFHKDCL 60
TRWLNRSRTC PQCRDPCDRR RVHRLYLNFA EAPEFDDTEL PKVAMDWVPI DLDRDSLPDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATTCTCCA GAGGTCATCT CTAATAAAGC AGGAAAGTTG ATACGAATCG TTTCGTTTTC 60
CGCTCATTGT TGTGAAATAA ATTTGGAACA GAAGAATAGA GCCACACATA TTCAAAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006616--DM9_repeat
IPR024518--DUF3421
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF11901--DUF3421
PF13639--zf-RING_2

SMART

SM00696--DM9
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0008340--P:determination of adult lifespan
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

dme:Dmel_CG10916

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ogl-077126	Oryza glaberrima	41.51	2.00e-09	54.70
IUUC-Olo-080603	Oryza longistaminata	41.67	2.00e-08	50.80
IUUC-Opu-083435	Oryza punctata	41.51	2.00e-09	54.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence