iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004758

Ensembl Protein ID

ENSACAP00000012985.3

UniProt Accession

G1KNF2; G1KNF2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

CFAP57

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000013236.3	ENSACAT00000013244.3	ENSACAP00000012985.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.60e-12	45.4	389	422
UBD/Beta-Prp	1.20e-44	152.6	389	672

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtg 33
           H++ +t+l+     +l++++s D+++++W++ t+
   Q: 389  HSSAITGLDTciRKPLVATCSLDKSVRIWNYETN 422
           999999997657558***************8775 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae..........................................v 55
           h+s it ++    k+l+at s d+++++w+++t +l   l++  +e                                           
   Q: 389  HSSAITGLDTCIRKPLVATCSLDKSVRIWNYETNSL--DLYKEYPEeaysltlhpsglyvlvgfadklrlmnlliddirtfkdftvrgC 475
           56778888888899*******************999..555555545555555566677777777777777777777777777777779 PP
   S: 56   tavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncv 143
           + ++fs  g  l  + + ++i++++  t++ ++ lkgh+ +v+s+ +s +++klvs +    +  w+l+tg+  +e +l  ++ + n+v
   Q: 476  RECTFSTGG-HLFAAVNGNVIHIYSSTTFENIINLKGHNGKVRSVVWSMDDYKLVSCGTEGAVYEWNLQTGKRESEcVL--KSCSYNGV 561
           ********9.799999**********************************************************96444..44569*** PP
   S: 144  vvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq...tgecvrtlnghtdnvksvr 229
           +++pd++++++ + D  ++   +   ++lr+     +   +++ + ++g+ + +g   gt++   +    ++e  +++++h  +v  + 
   Q: 562  AISPDSKVVFAVGSDHSIK--EICDSSILREVPT-FDVVYTCIVVAHSGRMVFTGTSTGTIRSMKYPlpvHKE-YNEYQAHAGPVAKMS 646
           *******************..88999******77.788888999******************99998996555.9************** PP
   S: 230  fspnderlvsgssDgsiriW...dlr 252
            + +d++l++ ++Dg i iW   d++
   Q: 647  ITADDQFLLTSAEDGCIIIWkvyDKE 672
           ********************655544 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSVIVAQALH IFGFQSRVAN NICFFDEQII VYPAGNSCVK YHIEQKWQKF IPGSEKSQGM 60
LALAISPNRR YLAISETLQD KPTITIYELS AVPCKKRKIL NSFDFSVQEF ISLAFSPDSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTGA TCGTGGCCCA AGCGCTCCAC ATATTTGGCT TCCAGTCCCG AGTGGCCAAT 60
AATATTTGTT TCTTTGACGA GCAGATCATA GTGTACCCCG CGGGAAACAG CTGCGTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001714	Ailuropoda melanoleuca	69.46	0.00e+00	1011.00
IUUC-Apl-003618	Anas platyrhynchos	68.35	0.00e+00	1031.00
IUUC-Ame-011060	Astyanax mexicanus	54.42	0.00e+00	1328.00
IUUC-Bta-012707	Bos taurus	65.73	0.00e+00	1589.00
IUUC-Cja-019396	Callithrix jacchus	67.96	0.00e+00	969.00
IUUC-Cfa-020454	Canis familiaris	72.27	0.00e+00	1859.00
IUUC-Cpo-022058	Cavia porcellus	71.94	0.00e+00	1781.00
IUUC-Cre-022624	Chlamydomonas reinhardtii	37.93	1.00e-168	587.00
IUUC-Csa-023207	Chlorocebus sabaeus	72.88	0.00e+00	1819.00
IUUC-Cho-025027	Choloepus hoffmanni	70.10	0.00e+00	890.00
IUUC-Cin-025464	Ciona intestinalis	62.73	3.00e-84	304.00
IUUC-Csv-025972	Ciona savignyi	55.47	0.00e+00	1255.00
IUUC-Dre-027808	Danio rerio	52.80	0.00e+00	1087.00
IUUC-Dno-028916	Dasypus novemcinctus	71.81	0.00e+00	1781.00
IUUC-Dor-031063	Dipodomys ordii	66.32	0.00e+00	707.00
IUUC-Dme-031680	Drosophila melanogaster	28.04	2.00e-114	406.00
IUUC-Ete-032391	Echinops telfairi	69.43	0.00e+00	873.00
IUUC-Eca-034029	Equus caballus	73.31	0.00e+00	1751.00
IUUC-Fca-035408	Felis catus	73.24	0.00e+00	1796.00
IUUC-Fal-036882	Ficedula albicollis	57.72	0.00e+00	1185.00
IUUC-Gmo-038581	Gadus morhua	52.11	3.00e-161	562.00
IUUC-Gga-041149	Gallus gallus	63.71	0.00e+00	1064.00
IUUC-Gac-042464	Gasterosteus aculeatus	46.77	0.00e+00	1075.00
IUUC-Ggo-045545	Gorilla gorilla	69.66	0.00e+00	1021.00
IUUC-Hsa-045981	Homo sapiens	70.00	0.00e+00	1800.00
IUUC-Itr-048616	Ictidomys tridecemlineatus	68.05	0.00e+00	670.00
IUUC-Loc-052681	Lepisosteus oculatus	67.95	0.00e+00	1711.00
IUUC-Laf-054188	Loxodonta africana	72.59	0.00e+00	1808.00
IUUC-Mcc-055587	Macaca mulatta	71.47	0.00e+00	1807.00
IUUC-Meu-056711	Macropus eugenii	75.89	1.00e-121	429.00
IUUC-Mga-059502	Meleagris gallopavo	61.23	0.00e+00	1330.00
IUUC-Mmr-061637	Microcebus murinus	69.64	0.00e+00	1775.00
IUUC-Mdo-062272	Monodelphis domestica	73.77	0.00e+00	1800.00
IUUC-Mmu-063404	Mus musculus	72.73	0.00e+00	1804.00
IUUC-Mpu-066252	Mustela putorius furo	72.76	0.00e+00	1833.00
IUUC-Mlu-067652	Myotis lucifugus	70.52	0.00e+00	1503.00
IUUC-Nle-069957	Nomascus leucogenys	66.37	0.00e+00	1604.00
IUUC-Opr-070883	Ochotona princeps	64.85	3.00e-172	598.00
IUUC-Ont-072023	Oreochromis niloticus	54.64	0.00e+00	1309.00
IUUC-Oan-073546	Ornithorhynchus anatinus	71.07	0.00e+00	717.00
IUUC-Ocu-073898	Oryctolagus cuniculus	72.65	0.00e+00	1782.00
IUUC-Ola-087473	Oryzias latipes	50.46	0.00e+00	674.00
IUUC-Olu-087727	Ostreococcus lucimarinus	27.16	6.00e-130	458.00
IUUC-Oga-088710	Otolemur garnettii	73.04	0.00e+00	1821.00
IUUC-Oar-089552	Ovis aries	72.35	0.00e+00	1822.00
IUUC-Ptr-090948	Pan troglodytes	69.40	0.00e+00	920.00
IUUC-Pan-091922	Papio anubis	73.79	0.00e+00	1387.00
IUUC-Psi-093500	Pelodiscus sinensis	79.24	0.00e+00	1549.00
IUUC-Ppa-095165	Physcomitrella patens	26.25	4.00e-87	316.00
IUUC-Pfo-096491	Poecilia formosa	48.95	0.00e+00	700.00
IUUC-Pab-098021	Pongo abelii	69.40	0.00e+00	920.00
IUUC-Pca-101136	Procavia capensis	66.67	9.00e-38	151.00
IUUC-Pva-102642	Pteropus vampyrus	69.30	0.00e+00	983.00
IUUC-Sha-106766	Sarcophilus harrisii	71.52	0.00e+00	1665.00
IUUC-Smo-108882	Selaginella moellendorffii	37.79	0.00e+00	742.00
IUUC-Ssc-116324	Sus scrofa	71.22	0.00e+00	1803.00
IUUC-Tgu-117260	Taeniopygia guttata	59.41	0.00e+00	920.00
IUUC-Tru-118464	Takifugu rubripes	52.09	0.00e+00	709.00
IUUC-Tsy-119582	Tarsius syrichta	66.75	7.00e-178	617.00
IUUC-Tni-120901	Tetraodon nigroviridis	52.78	0.00e+00	711.00
IUUC-Tbe-127270	Tupaia belangeri	60.58	0.00e+00	794.00
IUUC-Vpa-130565	Vicugna pacos	66.75	8.00e-179	620.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence