iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-31	107.3	178	213
UBD/Beta-Prp	9.40e-46	156.3	81	343

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.fsdtllvsGsdDgtikvWDlrtgvl 35
           gHt+ + +l  +++ ++vsGs D ti+ WDlr +v+
   Q: 178  GHTGHILSLYsWNNAMFVSGSQDQTIRFWDLRVNVS 213
           8*******9659669***************997765 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikv..wdvttgkl...lrslsgheaevtavkfspdgk....ilvtgse.Drtikvwdlstgkcvhtlkg 92
             +hh + i+c ++s+d++l+atgs d+tik   ++++t +l     +l  h+++v++++f +d++    +l++g+  D  i++ d  tg+++++++g
   Q: 81   RTKHHRGSIYCTCWSRDGELIATGSNDKTIKYmrFNNDTNQLvghEMELNMHDGTVRDMCFLDDSStksrLLASGGAgDCKIYITDCGTGTPFQAYSG 178
           5689**************************872255566666887788999**********999888999888887625778888************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee......tlsg..hdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           h+  +lsl +   +  +vsGs+d+tir wdl+ +  +++         g  ++++v+ v+v+p+g+llvsG++D+ + l+d++ ++ ++++   ht  
   Q: 179  HTGHILSLYSWN-NAMFVSGSQDQTIRFWDLRVNVSVNTldndrkD--GglESSAVTAVCVDPTGRLLVSGHADSSCTLYDIRGNRPIQRFYP-HTAE 272
           *******85444.6************************85544321..1235789************************************87.**** PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           ++++ f+++  +++++s+d++++l dlq    ++   + + +h+d    +r +p +  ++s+s+D++  +W
   Q: 273  IRCVRFSPSAYYMLTCSYDNSIRLTDLQgdlaHELSSVVVAEHKDKAITIRWHPTEFSFISTSADKTATLW 343
           ****************************99988877889999*************************9999 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MNPESRDLDL RKGDVERPHF EAVTTLSDSQ AIRSVDFHPN GKLYAVGSNS KTFRICQYPA 60
LSKLRHGHQA AVYPPSVLCK RTKHHRGSIY CTCWSRDGEL IATGSNDKTI KYMRFNNDTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCACTTTTG TTATTTCAAC CGTGGCGAGT TGTACGTTCT ATTACCTCGG ATGGCTTAGA 60
AACTGTGTGG TCGAAACAGA AACGATCCAA GCTCCAGAAA ATACTCGAAA TAAGTGTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

dme:Dmel_CG2812

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001519	Ailuropoda melanoleuca	52.73	2.00e-98	353.00
IUUC-Apl-003954	Anas platyrhynchos	53.47	2.00e-99	356.00
IUUC-Aca-004766	Anolis carolinensis	52.73	2.00e-98	352.00
IUUC-Ame-010725	Astyanax mexicanus	54.01	1.00e-98	353.00
IUUC-Bta-013072	Bos taurus	52.73	1.00e-98	353.00
IUUC-Cel-018667	Caenorhabditis elegans	50.30	8.00e-95	341.00
IUUC-Cja-018835	Callithrix jacchus	52.42	9.00e-98	350.00
IUUC-Cfa-020380	Canis familiaris	53.01	2.00e-98	352.00
IUUC-Cpo-021883	Cavia porcellus	52.73	6.00e-99	354.00
IUUC-Csa-023467	Chlorocebus sabaeus	52.42	4.00e-98	352.00
IUUC-Cho-024342	Choloepus hoffmanni	45.21	7.00e-77	281.00
IUUC-Cin-025112	Ciona intestinalis	39.18	6.00e-60	223.00
IUUC-Dre-027816	Danio rerio	53.47	1.00e-99	356.00
IUUC-Dno-029290	Dasypus novemcinctus	52.91	2.00e-98	353.00
IUUC-Dor-030258	Dipodomys ordii	45.15	2.00e-75	276.00
IUUC-Ete-032248	Echinops telfairi	50.82	2.00e-64	239.00
IUUC-Eca-033623	Equus caballus	52.73	1.00e-98	353.00
IUUC-Fca-036425	Felis catus	52.73	1.00e-98	353.00
IUUC-Fal-036661	Ficedula albicollis	52.73	2.00e-98	353.00
IUUC-Gmo-039527	Gadus morhua	52.74	5.00e-98	351.00
IUUC-Gga-041177	Gallus gallus	52.42	4.00e-98	352.00
IUUC-Gac-042049	Gasterosteus aculeatus	52.24	9.00e-98	350.00
IUUC-Ggo-044833	Gorilla gorilla	52.42	5.00e-98	351.00
IUUC-Hsa-046084	Homo sapiens	52.42	5.00e-98	351.00
IUUC-Lch-050313	Latimeria chalumnae	53.33	1.00e-99	357.00
IUUC-Loc-051790	Lepisosteus oculatus	52.25	3.00e-98	352.00
IUUC-Laf-053521	Loxodonta africana	52.73	5.00e-99	355.00
IUUC-Mcc-055053	Macaca mulatta	52.42	4.00e-98	351.00
IUUC-Meu-056734	Macropus eugenii	51.06	8.00e-95	340.00
IUUC-Mga-059381	Meleagris gallopavo	51.60	2.00e-97	349.00
IUUC-Mmr-060859	Microcebus murinus	52.73	2.00e-98	353.00
IUUC-Mdo-062501	Monodelphis domestica	50.83	3.00e-83	303.00
IUUC-Mmu-063126	Mus musculus	53.03	3.00e-99	355.00
IUUC-Mpu-066718	Mustela putorius furo	49.40	3.00e-41	162.00
IUUC-Mlu-067246	Myotis lucifugus	52.73	1.00e-98	353.00
IUUC-Nle-069807	Nomascus leucogenys	52.42	5.00e-98	351.00
IUUC-Opr-070862	Ochotona princeps	59.81	7.00e-37	148.00
IUUC-Ont-072376	Oreochromis niloticus	52.57	2.00e-97	349.00
IUUC-Oan-072740	Ornithorhynchus anatinus	52.73	2.00e-98	352.00
IUUC-Ocu-074898	Oryctolagus cuniculus	52.73	6.00e-99	354.00
IUUC-Ola-087341	Oryzias latipes	52.74	4.00e-97	348.00
IUUC-Oga-088563	Otolemur garnettii	52.73	8.00e-99	354.00
IUUC-Oar-089926	Ovis aries	52.73	1.00e-98	353.00
IUUC-Ptr-090706	Pan troglodytes	52.42	5.00e-98	351.00
IUUC-Pan-091740	Papio anubis	52.42	4.00e-98	352.00
IUUC-Psi-093938	Pelodiscus sinensis	52.69	1.00e-100	360.00
IUUC-Pfo-096531	Poecilia formosa	51.17	6.00e-97	348.00
IUUC-Pab-098312	Pongo abelii	52.42	5.00e-98	351.00
IUUC-Pca-101100	Procavia capensis	49.70	4.00e-88	318.00
IUUC-Pva-102734	Pteropus vampyrus	52.00	5.00e-56	212.00
IUUC-Rno-105625	Rattus norvegicus	53.33	1.00e-99	357.00
IUUC-Sha-106999	Sarcophilus harrisii	52.71	9.00e-100	357.00
IUUC-Sar-112988	Sorex araneus	53.89	1.00e-45	177.00
IUUC-Ssc-115384	Sus scrofa	52.73	3.00e-98	352.00
IUUC-Tgu-116808	Taeniopygia guttata	52.73	2.00e-98	352.00
IUUC-Tru-118233	Takifugu rubripes	51.18	2.00e-95	343.00
IUUC-Tsy-119509	Tarsius syrichta	43.64	1.00e-75	277.00
IUUC-Tni-120473	Tetraodon nigroviridis	52.35	3.00e-96	345.00
IUUC-Tbe-127447	Tupaia belangeri	51.89	2.00e-25	109.00
IUUC-Ttr-128459	Tursiops truncatus	52.73	2.00e-98	352.00
IUUC-Vpa-130258	Vicugna pacos	56.17	3.00e-51	196.00
IUUC-Xtr-132609	Xenopus tropicalis	49.70	8.00e-90	324.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence