iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-06	28.0	70	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd..tllvsGsdDgtikvWDl 30
           gH++sv+ + ++d    l s+  Dg+i+vW l
   Q: 70   GHKESVRVVTWNDaqQKLTSSDTDGVIMVWML 101
           8**********777789*************86 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MFVYLSKKIA IPNNVKLNCI AWNKEEGYIA VAGTDGLLKV LKLDQATPNG QSKGGLAAVS 60
NLSMNQTLDG HKESVRVVTW NDAQQKLTSS DTDGVIMVWM LYKGSWYEEM TNDRKKSTVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACTTGCCA CCAATACCAA TTGAACCACT TTTTGGGCCC AAAACAGGCT TGGGTCTTTG 60
GCCAGCTGAC AAACCGAAGT TGGGATCACC ATGGAAACCA ATTAGTTTTG CTGCCACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR017233--WDR35

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0030991--C:intraciliary transport particle A
GO:0097730--C:non-motile cilium
GO:0035091--F:phosphatidylinositol binding
GO:0060271--P:cilium assembly
GO:0035721--P:intraciliary retrograde transport
GO:0022008--P:neurogenesis
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium

KEGG

dme:Dmel_CG2069

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	26.18	6.00e-14	72.80
IUUC-Apl-004049	Anas platyrhynchos	47.59	0.00e+00	1110.00
IUUC-Aca-004767	Anolis carolinensis	25.09	1.00e-12	68.60
IUUC-Ame-011642	Astyanax mexicanus	21.77	1.00e-13	71.60
IUUC-Bta-012969	Bos taurus	26.18	4.00e-13	70.10
IUUC-Cja-019249	Callithrix jacchus	27.64	3.00e-14	73.90
IUUC-Cfa-020915	Canis familiaris	25.82	1.00e-12	68.20
IUUC-Cpo-021888	Cavia porcellus	26.91	6.00e-14	72.80
IUUC-Csa-023533	Chlorocebus sabaeus	26.74	5.00e-15	76.30
IUUC-Cin-025165	Ciona intestinalis	56.30	5.00e-101	360.00
IUUC-Dno-029699	Dasypus novemcinctus	55.94	5.00e-130	456.00
IUUC-Eca-033831	Equus caballus	26.18	1.00e-13	72.00
IUUC-Eeu-034919	Erinaceus europaeus	24.22	4.00e-07	50.10
IUUC-Fal-037340	Ficedula albicollis	21.51	4.00e-14	73.20
IUUC-Gmo-038607	Gadus morhua	46.97	0.00e+00	1107.00
IUUC-Gga-040595	Gallus gallus	22.51	8.00e-16	79.00
IUUC-Gac-041560	Gasterosteus aculeatus	47.35	0.00e+00	1092.00
IUUC-Ggo-045356	Gorilla gorilla	26.74	5.00e-15	76.30
IUUC-Hsa-046135	Homo sapiens	26.74	4.00e-15	76.60
IUUC-Itr-048228	Ictidomys tridecemlineatus	26.37	3.00e-14	73.90
IUUC-Lch-050449	Latimeria chalumnae	48.94	0.00e+00	1141.00
IUUC-Loc-052049	Lepisosteus oculatus	21.96	5.00e-13	69.70
IUUC-Laf-053728	Loxodonta africana	27.78	6.00e-14	72.80
IUUC-Mcc-054971	Macaca mulatta	26.74	6.00e-15	76.30
IUUC-Mga-059296	Meleagris gallopavo	22.47	5.00e-14	73.20
IUUC-Mdo-062115	Monodelphis domestica	26.18	2.00e-13	70.90
IUUC-Mmu-063664	Mus musculus	28.04	1.00e-14	75.10
IUUC-Mpu-066136	Mustela putorius furo	26.09	2.00e-13	71.60
IUUC-Mlu-068238	Myotis lucifugus	25.36	2.00e-12	68.20
IUUC-Nle-069003	Nomascus leucogenys	26.37	6.00e-14	72.80
IUUC-Ont-072080	Oreochromis niloticus	22.19	5.00e-14	73.20
IUUC-Ola-086538	Oryzias latipes	22.49	6.00e-13	69.70
IUUC-Oga-088722	Otolemur garnettii	27.94	5.00e-15	76.30
IUUC-Oar-089249	Ovis aries	26.55	6.00e-14	72.80
IUUC-Ptr-090752	Pan troglodytes	26.74	4.00e-15	77.00
IUUC-Pan-092472	Papio anubis	26.74	5.00e-15	76.30
IUUC-Psi-093525	Pelodiscus sinensis	48.69	0.00e+00	1149.00
IUUC-Pma-094159	Petromyzon marinus	48.86	1.00e-133	468.00
IUUC-Pfo-096526	Poecilia formosa	23.15	3.00e-15	77.40
IUUC-Pab-098428	Pongo abelii	27.11	3.00e-15	77.00
IUUC-Pca-100233	Procavia capensis	30.69	4.00e-05	43.50
IUUC-Rno-105764	Rattus norvegicus	28.41	4.00e-15	76.60
IUUC-Sha-106649	Sarcophilus harrisii	26.37	3.00e-14	73.90
IUUC-Tgu-116870	Taeniopygia guttata	22.65	2.00e-14	74.30
IUUC-Tni-120812	Tetraodon nigroviridis	21.56	2.00e-11	64.70
IUUC-Ttr-128862	Tursiops truncatus	25.82	4.00e-13	70.10
IUUC-Xtr-131914	Xenopus tropicalis	27.21	3.00e-12	67.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence