iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000012727.3	ENSMMUT00000017858.3	ENSMMUP00000016723.3
ENSMMUG00000012727.3	ENSMMUT00000017853.3	ENSMMUP00000016718.3
ENSMMUG00000012727.3	ENSMMUT00000017854.3	ENSMMUP00000016719.3
ENSMMUG00000012727.3	ENSMMUT00000017850.3	ENSMMUP00000016715.3
ENSMMUG00000012727.3	ENSMMUT00000017857.3	ENSMMUP00000016722.3
ENSMMUG00000012727.3	ENSMMUT00000045941.2	ENSMMUP00000038980.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-13	49.3	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MRAVLTWRDK AEHCINDIAF KPDGTQLILA AGNRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY TSWSVMFSLH LHLTFLGLRK TVRVTTTNKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGGCCG TGTTGACGTG GAGAGATAAA GCCGAGCACT GGTGAGAAGC CGGGCGGTCC 60
GCGAAAAGCG GGAGGTCGAG TCCCAGCGGG GACTGCGCGA GCCGCTGCAG CGTGTTTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005929--C:cilium
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0060271--P:cilium assembly
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	89.49	0.00e+00	2245.00
IUUC-Apl-003504	Anas platyrhynchos	85.61	0.00e+00	1764.00
IUUC-Aca-004767	Anolis carolinensis	80.50	0.00e+00	2076.00
IUUC-Ame-011642	Astyanax mexicanus	71.72	0.00e+00	1858.00
IUUC-Bta-012969	Bos taurus	87.45	0.00e+00	2185.00
IUUC-Cel-018670	Caenorhabditis elegans	36.88	0.00e+00	860.00
IUUC-Cja-019249	Callithrix jacchus	88.40	0.00e+00	2212.00
IUUC-Cfa-020915	Canis familiaris	90.19	0.00e+00	2220.00
IUUC-Cpo-021888	Cavia porcellus	88.10	0.00e+00	1803.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	46.69	0.00e+00	1092.00
IUUC-Csa-023533	Chlorocebus sabaeus	96.18	0.00e+00	2420.00
IUUC-Cin-025121	Ciona intestinalis	55.27	0.00e+00	1461.00
IUUC-Csv-026240	Ciona savignyi	56.08	0.00e+00	1410.00
IUUC-Dno-029685	Dasypus novemcinctus	83.16	0.00e+00	2076.00
IUUC-Dme-032005	Drosophila melanogaster	26.74	7.00e-09	57.00
IUUC-Ete-032682	Echinops telfairi	82.86	0.00e+00	1642.00
IUUC-Eca-033831	Equus caballus	90.10	0.00e+00	2300.00
IUUC-Eeu-034919	Erinaceus europaeus	83.54	0.00e+00	983.00
IUUC-Fca-036559	Felis catus	89.87	0.00e+00	2286.00
IUUC-Fal-037340	Ficedula albicollis	83.87	0.00e+00	1702.00
IUUC-Gga-040595	Gallus gallus	85.40	0.00e+00	1763.00
IUUC-Ggo-045356	Gorilla gorilla	97.36	0.00e+00	2484.00
IUUC-Hsa-046135	Homo sapiens	97.45	0.00e+00	2484.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	83.02	0.00e+00	1992.00
IUUC-Lch-050183	Latimeria chalumnae	80.06	0.00e+00	1142.00
IUUC-Loc-052049	Lepisosteus oculatus	76.30	0.00e+00	1976.00
IUUC-Laf-053728	Loxodonta africana	88.79	0.00e+00	2269.00
IUUC-Meu-056446	Macropus eugenii	82.74	0.00e+00	2107.00
IUUC-Mga-059296	Meleagris gallopavo	79.63	0.00e+00	2051.00
IUUC-Mmr-061232	Microcebus murinus	89.95	0.00e+00	2254.00
IUUC-Mdo-062115	Monodelphis domestica	87.60	0.00e+00	2235.00
IUUC-Mmu-063664	Mus musculus	88.15	0.00e+00	2285.00
IUUC-Mpu-066136	Mustela putorius furo	85.90	0.00e+00	2165.00
IUUC-Mlu-068238	Myotis lucifugus	86.52	0.00e+00	2215.00
IUUC-Nle-069003	Nomascus leucogenys	91.83	0.00e+00	2296.00
IUUC-Ont-072080	Oreochromis niloticus	72.41	0.00e+00	1894.00
IUUC-Oan-072891	Ornithorhynchus anatinus	75.97	0.00e+00	881.00
IUUC-Ocu-074262	Oryctolagus cuniculus	87.15	0.00e+00	2194.00
IUUC-Ola-086538	Oryzias latipes	71.40	0.00e+00	1832.00
IUUC-Oga-088722	Otolemur garnettii	89.78	0.00e+00	2222.00
IUUC-Oar-089249	Ovis aries	79.97	0.00e+00	1985.00
IUUC-Ptr-090752	Pan troglodytes	96.05	0.00e+00	2435.00
IUUC-Pan-092472	Papio anubis	96.34	0.00e+00	2419.00
IUUC-Psi-093335	Pelodiscus sinensis	86.20	0.00e+00	1782.00
IUUC-Pma-094520	Petromyzon marinus	67.50	0.00e+00	1590.00
IUUC-Ppa-095600	Physcomitrella patens	46.15	8.00e-33	132.00
IUUC-Pfo-096526	Poecilia formosa	69.30	0.00e+00	1768.00
IUUC-Pab-098428	Pongo abelii	96.87	0.00e+00	1214.00
IUUC-Pca-100233	Procavia capensis	71.86	0.00e+00	977.00
IUUC-Pva-103064	Pteropus vampyrus	80.72	0.00e+00	1965.00
IUUC-Rno-105764	Rattus norvegicus	88.54	0.00e+00	2263.00
IUUC-Sha-106649	Sarcophilus harrisii	87.04	0.00e+00	2206.00
IUUC-Smo-109287	Selaginella moellendorffii	38.67	0.00e+00	855.00
IUUC-Tgu-116870	Taeniopygia guttata	79.39	0.00e+00	1981.00
IUUC-Tru-118661	Takifugu rubripes	69.59	0.00e+00	1781.00
IUUC-Tsy-119640	Tarsius syrichta	93.03	4.00e-110	393.00
IUUC-Tni-120812	Tetraodon nigroviridis	69.19	0.00e+00	1764.00
IUUC-Ttr-128862	Tursiops truncatus	88.92	0.00e+00	2281.00
IUUC-Vpa-130049	Vicugna pacos	86.79	1.00e-153	537.00
IUUC-Xtr-131914	Xenopus tropicalis	74.90	0.00e+00	1932.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence