iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074216

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02039241

Gene Name

USP32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000009402.3	ENSOCUT00000009408.3	ENSOCUP00000008115.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.20e-107	357.3	733	1566

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 733  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 819
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 820  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 904
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 905  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglkpeqillaevhssniknfpqdnqkvrlsvsgfl 991
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 992  cafeipipaspvsasspvqtdfssspstngiftlttngdlprpifipngmpntvvpcgteknftngmvnghmpslpdnpftgyiiav 1078
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1079 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1165
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1166 cawcpwyrfcrgckidcgedrafignayiavdwdptalhlryqtsqervvdehesveqsrqaqaepiNLDSCLRAFTSEEELGENEM 1252
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1253 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalcqrklltpqgdelcearvp 1337
           ********************************99775..5569******************99999999999999999999999999 PP
   S: 268  ..............................................................................peekqke.. 274
                                                                                         +     +  
   Q: 1338 agevkrvdaqssageeevllskspsslsagvlgspkgspsssrksgtscpssknsspnssprtlgrskgrlrlpqigsK-----Nkl 1419
           9999999988888888888888888888888888888877777777777666666666666555555555555555550.....055 PP
   S: 275  ......................................................................................k 275
                                                                                                 k
   Q: 1420 ssskenldasrengsgqiceladalsrmhmlggsqpelvtpqdhevalangflyeheacgngysngqfgnhreedslddqredpriK 1506
           55555666666666666677777777777777777777777777777777777777777777777777778888888888888899* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1507 PIYNLYAISCHSGILGGGHYVTYAKNPNCKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1566
           *************************************************...********985 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MGAKESRIGF LSYEEALRRV TDVELKRLKD AFKRTCGLSY YMGQLCFIRE VLGDGVPPKV 60
AEVIYCSFGG TSKGLHFNNL IVGLVLLTRG RDEEKAKYIF SLFSSESGSY VVREEMERML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGCTCGG GCGGGTCTCG GGGTTCGGGA TTGGCGGGAC GGTGGGGATG ATGCGTTACG 60
TGCAGCGAGG CGGGCCCTCC TCCGACGCTC CTGCGCGCGT TTAGCGTGGG GCGGGGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	95.48	0.00e+00	2594.00
IUUC-Apl-003272	Anas platyrhynchos	83.48	0.00e+00	2651.00
IUUC-Aca-005057	Anolis carolinensis	84.51	0.00e+00	2302.00
IUUC-Ame-010781	Astyanax mexicanus	74.91	0.00e+00	2398.00
IUUC-Bta-013502	Bos taurus	91.45	0.00e+00	2791.00
IUUC-Cja-018754	Callithrix jacchus	96.38	0.00e+00	3077.00
IUUC-Cfa-020526	Canis familiaris	96.03	0.00e+00	3016.00
IUUC-Cpo-021568	Cavia porcellus	90.30	0.00e+00	2741.00
IUUC-Csa-023143	Chlorocebus sabaeus	96.51	0.00e+00	3043.00
IUUC-Cho-024603	Choloepus hoffmanni	62.76	0.00e+00	689.00
IUUC-Cin-025583	Ciona intestinalis	50.68	0.00e+00	1276.00
IUUC-Csv-026344	Ciona savignyi	47.49	0.00e+00	1177.00
IUUC-Dre-028121	Danio rerio	76.21	0.00e+00	2366.00
IUUC-Dno-029911	Dasypus novemcinctus	94.83	0.00e+00	2956.00
IUUC-Dor-030608	Dipodomys ordii	67.98	0.00e+00	684.00
IUUC-Dme-032094	Drosophila melanogaster	45.40	4.00e-124	440.00
IUUC-Ete-032639	Echinops telfairi	92.69	0.00e+00	1563.00
IUUC-Eca-034253	Equus caballus	95.97	0.00e+00	2997.00
IUUC-Eeu-035084	Erinaceus europaeus	80.94	0.00e+00	1587.00
IUUC-Fca-035474	Felis catus	95.13	0.00e+00	2475.00
IUUC-Fal-036985	Ficedula albicollis	85.04	0.00e+00	2624.00
IUUC-Gmo-039568	Gadus morhua	80.55	0.00e+00	2136.00
IUUC-Gga-040509	Gallus gallus	83.36	0.00e+00	2735.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.11	0.00e+00	2182.00
IUUC-Ggo-044956	Gorilla gorilla	88.37	0.00e+00	1836.00
IUUC-Hsa-046107	Homo sapiens	96.51	0.00e+00	3067.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	94.87	0.00e+00	1176.00
IUUC-Lch-050681	Latimeria chalumnae	78.12	0.00e+00	2404.00
IUUC-Loc-052474	Lepisosteus oculatus	77.98	0.00e+00	2480.00
IUUC-Laf-054273	Loxodonta africana	95.51	0.00e+00	3040.00
IUUC-Mcc-054718	Macaca mulatta	96.57	0.00e+00	3071.00
IUUC-Meu-056558	Macropus eugenii	72.53	0.00e+00	1416.00
IUUC-Mga-059892	Meleagris gallopavo	84.78	0.00e+00	2657.00
IUUC-Mmr-060866	Microcebus murinus	95.67	0.00e+00	3095.00
IUUC-Mdo-062607	Monodelphis domestica	91.46	0.00e+00	2961.00
IUUC-Mmu-063797	Mus musculus	95.26	0.00e+00	3091.00
IUUC-Mpu-066121	Mustela putorius furo	96.32	0.00e+00	3078.00
IUUC-Mlu-067581	Myotis lucifugus	94.35	0.00e+00	3031.00
IUUC-Nle-069916	Nomascus leucogenys	94.01	0.00e+00	2927.00
IUUC-Opr-071073	Ochotona princeps	86.52	0.00e+00	1224.00
IUUC-Ont-071310	Oreochromis niloticus	81.15	0.00e+00	2159.00
IUUC-Oan-073356	Ornithorhynchus anatinus	89.29	0.00e+00	2855.00
IUUC-Ola-087434	Oryzias latipes	80.80	0.00e+00	2089.00
IUUC-Oga-089034	Otolemur garnettii	95.92	0.00e+00	2964.00
IUUC-Oar-090369	Ovis aries	95.84	0.00e+00	3018.00
IUUC-Ptr-090605	Pan troglodytes	96.57	0.00e+00	3071.00
IUUC-Pan-092381	Papio anubis	96.49	0.00e+00	2990.00
IUUC-Psi-093819	Pelodiscus sinensis	86.49	0.00e+00	2736.00
IUUC-Pma-094480	Petromyzon marinus	64.29	0.00e+00	1482.00
IUUC-Pfo-096561	Poecilia formosa	80.14	0.00e+00	2127.00
IUUC-Pab-097643	Pongo abelii	93.70	0.00e+00	2950.00
IUUC-Pca-100944	Procavia capensis	77.99	0.00e+00	1027.00
IUUC-Pva-102732	Pteropus vampyrus	85.96	0.00e+00	2662.00
IUUC-Rno-105113	Rattus norvegicus	95.21	0.00e+00	3026.00
IUUC-Sha-107608	Sarcophilus harrisii	81.03	2.00e-167	581.00
IUUC-Sar-113201	Sorex araneus	83.15	0.00e+00	1682.00
IUUC-Ssc-115469	Sus scrofa	92.54	0.00e+00	637.00
IUUC-Tgu-117322	Taeniopygia guttata	86.18	0.00e+00	2769.00
IUUC-Tru-118705	Takifugu rubripes	69.16	0.00e+00	682.00
IUUC-Tsy-119433	Tarsius syrichta	82.69	0.00e+00	1452.00
IUUC-Tni-120631	Tetraodon nigroviridis	79.15	0.00e+00	2101.00
IUUC-Tbe-127553	Tupaia belangeri	88.55	0.00e+00	688.00
IUUC-Ttr-128260	Tursiops truncatus	94.95	0.00e+00	3017.00
IUUC-Vpa-130479	Vicugna pacos	90.73	0.00e+00	2817.00
IUUC-Xtr-132686	Xenopus tropicalis	82.76	0.00e+00	2598.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence