iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134132

Ensembl Protein ID

ENSXMAP00000009479.1

UniProt Accession

M4A4T5; M4A4T5_XIPMA

Genbank Protein ID

ENSXMAP00000009479

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01040742

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000009437.1	ENSXMAT00000009493.1	ENSXMAP00000009479.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.40e-106	354.2	267	1106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l +++l+ ++  +ln+ np ++ g+++k++ +l+ elw++++k+++p +l  +++k+a++f+g
   Q: 267  TGLSNLGNTCFMNSSIQCVSNTKPLSDYFLSgRHLYELNRINPIGMRGHMAKCYGDLVLELWSGTQKSIAPLKLRWTIAKYAPRFNG 353
           7******************************99****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s r++p
   Q: 354  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaseAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISARFDP 438
           ********************************9999..5555566777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++++++e                                                                      
   Q: 439  FNFLSLPLPMDSSMHLEitvikldgstpvryglrlnmdekytglkkllselcslkpeqillaevhasniknfpqdnqkvrlsvngfl 525
           ************99999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 526  cafevpvpgsptslssptltgysplaadfsltgditptvngsaanghlianggpgtllpctpetplvngvanghmspmqdspfigyi 612
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 613  iamhrkmmrtelyflssqknrpslfgmplivpctvhtskkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvgkd 699
           *************************************************************************************** PP
   S: 186  ......................................................................slqdcLesftkeeeleg 202
                                                                                 sl++cL++ft+eeel +
   Q: 700  gnscawcpwyrfcrgctiectedrasvgnayiavdwdptalhlryqtsqeriveehcsveqsrraqaepiSLDSCLKAFTSEEELGE 786
           *************************************************************************************** PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts..................... 267
           ++ yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+  +d s f++                      
   Q: 787  DELYYCSKCKTHRLATKKLDLWRLPPILIVHLKRFQFVNG--RWIKSQKIVKFPRGsFDPSAFLAPrdlehrslhsrsesegllrvg 871
           ***********************************99775..5569********999*********777777777777777777777 PP
   S: 268  .....................................................................peekqke........... 274
                                                                                p     +           
   Q: 872  ednlssisapagfcnlpkgtstnfllseslrskvsspassrrsapslsrnsspsgspkpagrrpgrlrlP-----Qlgskhrlsssk 953
           7777777777777777666666666666666666666666666666655555555555555555555550.....055555555555 PP
   S: 275  ....................................................................................... 274
                                                                                                  
   Q: 954  enldgaasseadsrdgvsqadteervaiaagagpvgssdqaasesscgteassshcdvilmngdsngmgsdcsiesnvdpdssllqh 1040
           555666666666666666666777777777777777777777778888888888888889999999999999999999999999999 PP
   S: 275  .....kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                +  Y+L+a+ +HsG +++GHYv+y+kn ++kW++++Ds+++ev+ ee+ +   ++aY+lfY+++
   Q: 1041 rdmclDPLYNLYAISCHSGIMGGGHYVTYAKNPNDKWYCYNDSSCKEVHSEEIDT---DSAYILFYEQQ 1106
           9**99**************************************************...********985 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MDVDLLSPTA LSPQLAPSAA ESCFARQHNI SENNNQCFSG ANGHLPSQLT AQRPGAIDNQ 60
SLVTTDPIKA PTLTMEGGRL KRSLQLVPGR DFEMVPEPVW RALYHWYGAN LSLPRPVILE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTAAACTGA TGGTTCTGTA GATTTCAAAT CAGTTCAGAA ATCTTGGTAT AGTTATGAAA 60
CAGCTATATG AAGGCTTCAG CCACCAGATT GAAAGAGTTC CCATCCATAT AAGACATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	74.13	0.00e+00	1671.00
IUUC-Apl-003272	Anas platyrhynchos	81.95	0.00e+00	1419.00
IUUC-Aca-005057	Anolis carolinensis	81.89	0.00e+00	1383.00
IUUC-Ame-010781	Astyanax mexicanus	77.53	0.00e+00	1735.00
IUUC-Bta-013502	Bos taurus	73.68	0.00e+00	1661.00
IUUC-Cja-018754	Callithrix jacchus	73.12	0.00e+00	1649.00
IUUC-Cfa-020526	Canis familiaris	73.53	0.00e+00	1657.00
IUUC-Cpo-021568	Cavia porcellus	73.95	0.00e+00	1652.00
IUUC-Csa-023143	Chlorocebus sabaeus	75.20	0.00e+00	1658.00
IUUC-Cho-024603	Choloepus hoffmanni	90.64	3.00e-111	397.00
IUUC-Cin-025583	Ciona intestinalis	54.39	0.00e+00	858.00
IUUC-Csv-026344	Ciona savignyi	48.20	0.00e+00	768.00
IUUC-Dre-028121	Danio rerio	77.20	0.00e+00	1708.00
IUUC-Dno-029911	Dasypus novemcinctus	73.97	0.00e+00	1655.00
IUUC-Dor-030608	Dipodomys ordii	56.67	1.00e-162	567.00
IUUC-Dme-032094	Drosophila melanogaster	45.45	1.00e-121	432.00
IUUC-Ete-032639	Echinops telfairi	83.72	0.00e+00	1118.00
IUUC-Eca-034253	Equus caballus	74.78	0.00e+00	1663.00
IUUC-Eeu-035084	Erinaceus europaeus	70.45	0.00e+00	739.00
IUUC-Fca-035474	Felis catus	84.11	0.00e+00	1464.00
IUUC-Fal-036985	Ficedula albicollis	73.02	0.00e+00	1638.00
IUUC-Gmo-039568	Gadus morhua	88.41	0.00e+00	1504.00
IUUC-Gga-040509	Gallus gallus	84.61	0.00e+00	1488.00
IUUC-Gac-041757	Gasterosteus aculeatus	82.23	0.00e+00	1820.00
IUUC-Ggo-044956	Gorilla gorilla	76.07	0.00e+00	795.00
IUUC-Hsa-046107	Homo sapiens	74.93	0.00e+00	1657.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	67.10	0.00e+00	820.00
IUUC-Lch-050681	Latimeria chalumnae	70.16	0.00e+00	1520.00
IUUC-Loc-052474	Lepisosteus oculatus	75.59	0.00e+00	1713.00
IUUC-Laf-054273	Loxodonta africana	74.32	0.00e+00	1646.00
IUUC-Mcc-054718	Macaca mulatta	84.23	0.00e+00	1467.00
IUUC-Meu-056558	Macropus eugenii	62.78	4.00e-173	602.00
IUUC-Mga-059892	Meleagris gallopavo	85.07	0.00e+00	1481.00
IUUC-Mmr-060866	Microcebus murinus	73.81	0.00e+00	1662.00
IUUC-Mdo-062607	Monodelphis domestica	74.69	0.00e+00	1665.00
IUUC-Mmu-063797	Mus musculus	74.32	0.00e+00	1692.00
IUUC-Mpu-066121	Mustela putorius furo	72.59	0.00e+00	1665.00
IUUC-Mlu-067581	Myotis lucifugus	83.51	0.00e+00	1483.00
IUUC-Nle-069916	Nomascus leucogenys	81.62	0.00e+00	1408.00
IUUC-Opr-071073	Ochotona princeps	70.90	5.00e-100	360.00
IUUC-Ont-071310	Oreochromis niloticus	92.63	0.00e+00	1638.00
IUUC-Oan-073356	Ornithorhynchus anatinus	73.89	0.00e+00	1681.00
IUUC-Ocu-074216	Oryctolagus cuniculus	75.11	0.00e+00	1659.00
IUUC-Ola-087434	Oryzias latipes	83.70	0.00e+00	1798.00
IUUC-Oga-089034	Otolemur garnettii	74.14	0.00e+00	1666.00
IUUC-Oar-090369	Ovis aries	74.10	0.00e+00	1690.00
IUUC-Ptr-090605	Pan troglodytes	84.35	0.00e+00	1468.00
IUUC-Pan-092381	Papio anubis	84.35	0.00e+00	1466.00
IUUC-Psi-093819	Pelodiscus sinensis	85.30	0.00e+00	1502.00
IUUC-Pma-094480	Petromyzon marinus	64.27	0.00e+00	985.00
IUUC-Pfo-096561	Poecilia formosa	93.84	0.00e+00	1979.00
IUUC-Pab-097643	Pongo abelii	74.32	0.00e+00	1642.00
IUUC-Pca-100944	Procavia capensis	66.94	0.00e+00	826.00
IUUC-Pva-102732	Pteropus vampyrus	68.59	0.00e+00	1497.00
IUUC-Rno-105113	Rattus norvegicus	74.56	0.00e+00	1674.00
IUUC-Sar-113201	Sorex araneus	64.55	0.00e+00	1307.00
IUUC-Tgu-117322	Taeniopygia guttata	73.88	0.00e+00	1658.00
IUUC-Tru-118705	Takifugu rubripes	79.61	0.00e+00	697.00
IUUC-Tsy-119433	Tarsius syrichta	74.35	0.00e+00	1101.00
IUUC-Tni-120631	Tetraodon nigroviridis	81.43	0.00e+00	1791.00
IUUC-Tbe-127553	Tupaia belangeri	92.31	3.00e-153	536.00
IUUC-Ttr-128260	Tursiops truncatus	73.36	0.00e+00	1645.00
IUUC-Vpa-130479	Vicugna pacos	69.22	0.00e+00	1495.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence