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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063782
UUCD1 version UUC-MuM-00217
Ensembl Protein ID ENSMUSP00000047683.7
UniProt Accession F6YRW4; F6YRW4_MOUSE
Genbank Protein ID EDL33045.1
Protein Name F-box and leucine-rich repeat protein 11; Lysine-specific demethylase 2A
Genbank Nucleotide ID AC140073
Gene Name Kdm2a; Fbxl11; mCG_8391
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000054611.16 ENSMUST00000047898.13 ENSMUSP00000047683.7
ENSMUSG00000054611.16 ENSMUST00000176532.1 ENSMUSP00000135418.1
ENSMUSG00000054611.16 ENSMUST00000176653.1 ENSMUSP00000135745.1
ENSMUSG00000054611.16 ENSMUST00000176497.1 ENSMUSP00000135471.1
ENSMUSG00000054611.16 ENSMUST00000116571.8 ENSMUSP00000139651.1
ENSMUSG00000054611.16 ENSMUST00000175959.1 ENSMUSP00000135689.1
ENSMUSG00000054611.16 ENSMUST00000176483.2 ENSMUSP00000140253.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLMPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 6.80e-10 40.1 619 677
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedek......slveCekCrewfHpaClkls....veeelpnsekwiCpkCrs 53
            C +Cge +++e+      +l+eC++C+e++Hp+Cl++      +eelpn+  w+CpkC +
   Q: 619  TCSLCGEVDQNEEtqdfekKLMECCICNEIVHPGCLQMDgeglLNEELPNC--WECPKCYQ 677
           7*********995555666***********************99*******..******76 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MEPEEERIRY SQRLRGTMRR RYEDDGISDD EIEGKRTFDL EEKLQTNKYN ANFVTFMEGK 60
DFNVEYIQRG GLRDPLIFKN SDGLGIKMPD PDFTVNDVKM CVGSRRMVDV MDVNTQKGIE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063782|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCACCGGCGC TACGGAAACC TGAGCGTGGC CAACAGCAGG GGCTCCCTGG GCCACCTCCC 60
TGGGAGCCTG CGGCCCGCAG TGGGGTGTGC TAGCTGCTGC CACCCCTGAG CCGTCGTGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063782|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR019786--Zinc_finger_PHD-type_CS
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC
SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0070544--P:histone H3-K36 demethylation
KEGG mmu:225876
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002052 Ailuropoda melanoleuca 87.04 0.00e+00 1135.00
IUUC-Apl-003192 Anas platyrhynchos 77.97 0.00e+00 1050.00
IUUC-Aca-004576 Anolis carolinensis 83.92 0.00e+00 1907.00
IUUC-Ago-007912 Ashbya gossypii 41.31 7.00e-52 198.00
IUUC-Ame-011753 Astyanax mexicanus 58.87 0.00e+00 814.00
IUUC-Bta-012730 Bos taurus 85.28 0.00e+00 1834.00
IUUC-Bra-016717 Brassica rapa 23.77 4.00e-09 55.10
IUUC-Cja-019030 Callithrix jacchus 96.99 0.00e+00 2107.00
IUUC-Cfa-020644 Canis familiaris 97.16 0.00e+00 2134.00
IUUC-Cpo-022055 Cavia porcellus 96.81 0.00e+00 2098.00
IUUC-Csa-023379 Chlorocebus sabaeus 96.86 0.00e+00 2072.00
IUUC-Cho-024541 Choloepus hoffmanni 75.11 0.00e+00 1400.00
IUUC-Cin-025140 Ciona intestinalis 60.73 6.00e-107 382.00
IUUC-Csv-025861 Ciona savignyi 58.59 5.00e-121 428.00
IUUC-Cne-026797 Cryptococcus neoformans 38.51 6.00e-59 222.00
IUUC-Dre-028182 Danio rerio 59.79 0.00e+00 764.00
IUUC-Dno-029268 Dasypus novemcinctus 96.03 0.00e+00 2085.00
IUUC-Dor-031142 Dipodomys ordii 95.83 0.00e+00 1003.00
IUUC-Dme-032039 Drosophila melanogaster 61.35 9.00e-125 442.00
IUUC-Ete-032467 Echinops telfairi 86.79 0.00e+00 1866.00
IUUC-Eca-033526 Equus caballus 96.30 0.00e+00 2101.00
IUUC-Eeu-035273 Erinaceus europaeus 82.51 0.00e+00 1400.00
IUUC-Fca-035532 Felis catus 96.78 0.00e+00 2068.00
IUUC-Fal-037140 Ficedula albicollis 86.62 0.00e+00 1916.00
IUUC-Gmo-038932 Gadus morhua 58.69 0.00e+00 793.00
IUUC-Gga-040418 Gallus gallus 82.97 0.00e+00 1091.00
IUUC-Gac-041674 Gasterosteus aculeatus 55.27 0.00e+00 1196.00
IUUC-Ggo-045330 Gorilla gorilla 92.50 0.00e+00 788.00
IUUC-Hsa-046180 Homo sapiens 96.82 0.00e+00 2141.00
IUUC-Itr-048198 Ictidomys tridecemlineatus 96.31 0.00e+00 1398.00
IUUC-Lch-049730 Latimeria chalumnae 58.97 0.00e+00 974.00
IUUC-Laf-053939 Loxodonta africana 95.82 0.00e+00 2102.00
IUUC-Mcc-054600 Macaca mulatta 96.82 0.00e+00 2103.00
IUUC-Meu-056314 Macropus eugenii 90.54 0.00e+00 1179.00
IUUC-Mga-059549 Meleagris gallopavo 78.30 0.00e+00 1123.00
IUUC-Mmr-060865 Microcebus murinus 97.07 0.00e+00 2123.00
IUUC-Mdo-062567 Monodelphis domestica 93.72 0.00e+00 2055.00
IUUC-Mpu-066055 Mustela putorius furo 96.82 0.00e+00 2137.00
IUUC-Mlu-067228 Myotis lucifugus 88.81 0.00e+00 1128.00
IUUC-Nle-069668 Nomascus leucogenys 96.90 0.00e+00 2102.00
IUUC-Opr-070225 Ochotona princeps 95.07 0.00e+00 2056.00
IUUC-Ont-071349 Oreochromis niloticus 52.63 0.00e+00 1086.00
IUUC-Oan-073668 Ornithorhynchus anatinus 79.50 0.00e+00 672.00
IUUC-Ocu-074710 Oryctolagus cuniculus 97.33 0.00e+00 2078.00
IUUC-Ola-087410 Oryzias latipes 57.52 0.00e+00 768.00
IUUC-Oga-088644 Otolemur garnettii 96.73 0.00e+00 2015.00
IUUC-Oar-089193 Ovis aries 95.39 0.00e+00 2040.00
IUUC-Ptr-091523 Pan troglodytes 96.82 0.00e+00 2141.00
IUUC-Pan-092415 Papio anubis 96.90 0.00e+00 2108.00
IUUC-Psi-093607 Pelodiscus sinensis 87.86 0.00e+00 1035.00
IUUC-Ppa-095609 Physcomitrella patens 37.58 3.00e-58 218.00
IUUC-Pfo-096695 Poecilia formosa 50.00 0.00e+00 1069.00
IUUC-Pab-098580 Pongo abelii 97.01 0.00e+00 1217.00
IUUC-Pca-100670 Procavia capensis 91.58 0.00e+00 1503.00
IUUC-Pva-102416 Pteropus vampyrus 90.17 0.00e+00 1902.00
IUUC-Pgr-103554 Puccinia graminis 44.67 3.00e-74 273.00
IUUC-Rno-105814 Rattus norvegicus 99.05 0.00e+00 2181.00
IUUC-Sce-106445 Saccharomyces cerevisiae 40.68 3.00e-50 192.00
IUUC-Sha-106693 Sarcophilus harrisii 93.09 0.00e+00 1932.00
IUUC-Sar-113568 Sorex araneus 93.03 0.00e+00 1996.00
IUUC-Sre-115112 Sporisorium reilianum 40.94 1.00e-59 224.00
IUUC-Ssc-116337 Sus scrofa 95.30 0.00e+00 1534.00
IUUC-Tgu-117298 Taeniopygia guttata 87.29 0.00e+00 1918.00
IUUC-Tru-117874 Takifugu rubripes 56.67 0.00e+00 760.00
IUUC-Tsy-119293 Tarsius syrichta 95.16 0.00e+00 2013.00
IUUC-Tni-120020 Tetraodon nigroviridis 56.51 0.00e+00 762.00
IUUC-Tbe-127450 Tupaia belangeri 84.39 0.00e+00 1734.00
IUUC-Ttr-128837 Tursiops truncatus 86.21 0.00e+00 901.00
IUUC-Uma-129458 Ustilago maydis 40.31 5.00e-60 225.00
IUUC-Vpa-130655 Vicugna pacos 90.69 0.00e+00 1467.00
Created Date 25-Jun-2017

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