iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054579

UUCD1 version

UUC-LoA-00613

Ensembl Protein ID

ENSLAFP00000015010.3

UniProt Accession

G3TJS6; G3TJS6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000017907.3	ENSLAFT00000017907.3	ENSLAFP00000015010.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.50e-17	61.8	77	148
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.80e-09	34.9	181	211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv....g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v    +   +f ahk+vLa+sS+vF+a+f+++l+e+   + v i+++ p+v++ l++F Yt ++++ 
   Q: 77   CDVTLQVkyedApAAQFMAHKVVLASSSPVFKAMFTNGLREQG-MEVVSIEGIHPKVMERLIEFAYTASISMG 148
           8******66652699**************************98.***********************998875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c +L+++a+++i  hF
   Q: 181  PSNAIGIANFAEQIGCAELHQRAREYIYMHF 211
           89****************************9 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MQLEPKPSRA GAHSRFLPLQ SQCPKGAGDA VMYASTECKA EVTPSQHGNR TFSYTLEDHT 60
KQAFGIMNEL RLSQQLCDVT LQVKYEDAPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTGG AACCCAAGCC TAGCAGGGCT GGGGCCCACA GCCGATTCCT GCCCCTGCAG 60
TCGCAGTGCC CCAAGGGGGC AGGGGACGCA GTGATGTATG CCTCTACCGA GTGTAAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005884--C:actin filament
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0005654--C:nucleoplasm
GO:0071353--P:cellular response to interleukin-4
GO:0001701--P:in utero embryonic development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0045604--P:regulation of epidermal cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

lav:100662208

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	96.96	0.00e+00	1273.00
IUUC-Aca-005389	Anolis carolinensis	86.34	0.00e+00	1090.00
IUUC-Ame-010749	Astyanax mexicanus	78.57	0.00e+00	972.00
IUUC-Bta-013505	Bos taurus	96.63	0.00e+00	1272.00
IUUC-Cja-018823	Callithrix jacchus	96.63	0.00e+00	1270.00
IUUC-Cfa-021202	Canis familiaris	97.12	0.00e+00	1273.00
IUUC-Cpo-021830	Cavia porcellus	95.63	0.00e+00	842.00
IUUC-Csa-023728	Chlorocebus sabaeus	97.12	0.00e+00	1276.00
IUUC-Cin-025195	Ciona intestinalis	55.17	0.00e+00	679.00
IUUC-Csv-026155	Ciona savignyi	53.77	0.00e+00	628.00
IUUC-Dre-027388	Danio rerio	77.08	0.00e+00	948.00
IUUC-Dno-029066	Dasypus novemcinctus	85.60	0.00e+00	1089.00
IUUC-Dor-030674	Dipodomys ordii	94.40	0.00e+00	832.00
IUUC-Dme-032165	Drosophila melanogaster	49.20	1.00e-160	560.00
IUUC-Ete-032255	Echinops telfairi	95.05	2.00e-100	358.00
IUUC-Eca-034381	Equus caballus	93.60	0.00e+00	1209.00
IUUC-Eeu-034791	Erinaceus europaeus	92.36	0.00e+00	821.00
IUUC-Fca-036067	Felis catus	96.96	0.00e+00	1274.00
IUUC-Gmo-039691	Gadus morhua	76.87	0.00e+00	950.00
IUUC-Gga-040266	Gallus gallus	79.70	0.00e+00	1006.00
IUUC-Gac-041866	Gasterosteus aculeatus	76.95	0.00e+00	953.00
IUUC-Ggo-044719	Gorilla gorilla	97.12	0.00e+00	1275.00
IUUC-Hsa-046255	Homo sapiens	97.12	0.00e+00	1275.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	97.28	0.00e+00	1275.00
IUUC-Lch-049646	Latimeria chalumnae	83.39	0.00e+00	1048.00
IUUC-Loc-052296	Lepisosteus oculatus	56.97	0.00e+00	645.00
IUUC-Mcc-055315	Macaca mulatta	97.12	0.00e+00	1276.00
IUUC-Meu-056288	Macropus eugenii	89.23	0.00e+00	1121.00
IUUC-Mmr-061639	Microcebus murinus	96.96	0.00e+00	1279.00
IUUC-Mdo-062072	Monodelphis domestica	95.27	0.00e+00	1221.00
IUUC-Mmu-063622	Mus musculus	93.59	0.00e+00	1234.00
IUUC-Mpu-066737	Mustela putorius furo	94.87	0.00e+00	1236.00
IUUC-Mlu-068173	Myotis lucifugus	96.79	0.00e+00	1271.00
IUUC-Nle-069336	Nomascus leucogenys	62.06	0.00e+00	711.00
IUUC-Opr-070432	Ochotona princeps	96.49	0.00e+00	1224.00
IUUC-Ont-072160	Oreochromis niloticus	77.14	0.00e+00	949.00
IUUC-Oan-072691	Ornithorhynchus anatinus	81.01	0.00e+00	986.00
IUUC-Ocu-073798	Oryctolagus cuniculus	95.67	0.00e+00	1259.00
IUUC-Ola-086367	Oryzias latipes	74.70	0.00e+00	917.00
IUUC-Oga-088231	Otolemur garnettii	97.28	0.00e+00	1278.00
IUUC-Oar-089227	Ovis aries	95.35	0.00e+00	1246.00
IUUC-Ptr-091460	Pan troglodytes	97.12	0.00e+00	1275.00
IUUC-Pan-092713	Papio anubis	97.12	0.00e+00	1276.00
IUUC-Pfo-096468	Poecilia formosa	77.93	0.00e+00	955.00
IUUC-Pab-098357	Pongo abelii	97.12	0.00e+00	1276.00
IUUC-Pca-100837	Procavia capensis	96.79	0.00e+00	1270.00
IUUC-Pva-103249	Pteropus vampyrus	94.71	0.00e+00	1212.00
IUUC-Rno-106086	Rattus norvegicus	93.11	0.00e+00	1221.00
IUUC-Sha-107245	Sarcophilus harrisii	94.78	0.00e+00	1216.00
IUUC-Sar-112985	Sorex araneus	95.19	0.00e+00	1256.00
IUUC-Ssc-115756	Sus scrofa	97.60	0.00e+00	1283.00
IUUC-Tgu-116838	Taeniopygia guttata	53.40	4.00e-118	417.00
IUUC-Tru-117644	Takifugu rubripes	77.48	0.00e+00	973.00
IUUC-Tni-120245	Tetraodon nigroviridis	78.19	0.00e+00	964.00
IUUC-Tbe-127472	Tupaia belangeri	97.55	5.00e-149	521.00
IUUC-Ttr-128953	Tursiops truncatus	96.09	0.00e+00	712.00
IUUC-Vpa-130683	Vicugna pacos	94.20	0.00e+00	1108.00
IUUC-Xtr-132827	Xenopus tropicalis	76.28	0.00e+00	953.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence