iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	miRecords	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-31	106.4	361	393
UBD/Beta-Prp	1.30e-51	175.6	152	243

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrt 32
           gHt+ vt+  f  d+ +vsGsdD tikvW+lr 
   Q: 361  GHTETVTSSVFaRDDKVVSGSDDRTIKVWELRN 393
           8*******88**9999**************975 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghd 137
           ++r++ gh++++++v  +  ++i+ t+s D+t+++w +++  c+  ++gh  sv s++f++++d +++Gs d t+++w+   ++++  +++gh+
   Q: 152  VVREFGGHKDGIWQVAAKAGQPIIGTASADHTACIWGVESARCLLQYQGHAGSVNSIKFHQQRDLVLTGSGDGTAHIWQAAVNWEV--PKKGHS 243
           38999********************************************************************************9..588886 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MKASKTRAVR LTSLTEDVAA VPEDAPFRAR LHVLFAQIER EFEQLYLENQ ALQEKLDIAT 60
TTKESLIPPD ARSAAGGSMS TQASSAALAT PATQTDEVAG SFLAAASSTH KSLKAKLSSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCACAAAAA CACCTGCAAT AAGTATATTA TCATTGCGAA AACCAAGTGC AACAGCAGTT 60
CCCCAGTCAG CCAAAGAGGC AAATGCATCG CCAGCAGCGG AAGATGGATC AATAGAGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0046331--P:lateral inhibition
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

dme:Dmel_CG12333

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	50.10	1.00e-123	435.00
IUUC-Apl-003647	Anas platyrhynchos	49.47	7.00e-120	423.00
IUUC-Aca-004759	Anolis carolinensis	50.11	2.00e-123	435.00
IUUC-Ame-011103	Astyanax mexicanus	50.81	2.00e-26	112.00
IUUC-Bta-012718	Bos taurus	50.00	2.00e-122	431.00
IUUC-Cel-018499	Caenorhabditis elegans	38.09	7.00e-85	306.00
IUUC-Cja-019492	Callithrix jacchus	50.11	3.00e-124	437.00
IUUC-Cfa-020199	Canis familiaris	51.48	5.00e-126	443.00
IUUC-Cpo-022500	Cavia porcellus	45.78	2.00e-110	392.00
IUUC-Csa-023567	Chlorocebus sabaeus	50.74	9.00e-125	439.00
IUUC-Cho-025071	Choloepus hoffmanni	38.00	1.00e-60	226.00
IUUC-Cin-025460	Ciona intestinalis	39.13	4.00e-86	310.00
IUUC-Csv-026042	Ciona savignyi	39.83	2.00e-89	322.00
IUUC-Dre-028214	Danio rerio	49.68	1.00e-121	429.00
IUUC-Dno-029826	Dasypus novemcinctus	53.63	2.00e-117	415.00
IUUC-Dor-030967	Dipodomys ordii	50.81	4.00e-109	387.00
IUUC-Ete-032452	Echinops telfairi	48.09	4.00e-116	410.00
IUUC-Eca-033278	Equus caballus	50.00	9.00e-125	439.00
IUUC-Eeu-034592	Erinaceus europaeus	44.26	1.00e-96	345.00
IUUC-Fca-036431	Felis catus	51.27	7.00e-126	443.00
IUUC-Fal-037149	Ficedula albicollis	50.11	3.00e-121	427.00
IUUC-Gmo-038476	Gadus morhua	48.28	7.00e-115	406.00
IUUC-Gga-041099	Gallus gallus	49.68	5.00e-121	427.00
IUUC-Gac-042374	Gasterosteus aculeatus	48.84	5.00e-115	407.00
IUUC-Ggo-044683	Gorilla gorilla	49.79	6.00e-119	420.00
IUUC-Hsa-046658	Homo sapiens	50.64	7.00e-125	439.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	50.21	6.00e-125	439.00
IUUC-Lch-050571	Latimeria chalumnae	49.90	7.00e-122	429.00
IUUC-Loc-052652	Lepisosteus oculatus	49.79	1.00e-121	429.00
IUUC-Laf-053712	Loxodonta africana	49.06	7.00e-120	423.00
IUUC-Mcc-055521	Macaca mulatta	50.74	9.00e-125	439.00
IUUC-Meu-056324	Macropus eugenii	47.35	7.00e-111	393.00
IUUC-Mga-060114	Meleagris gallopavo	49.16	5.00e-122	430.00
IUUC-Mmr-061176	Microcebus murinus	50.95	4.00e-124	437.00
IUUC-Mdo-061888	Monodelphis domestica	48.95	7.00e-120	423.00
IUUC-Mmu-063977	Mus musculus	50.63	5.00e-126	443.00
IUUC-Mpu-066220	Mustela putorius furo	48.07	6.00e-65	240.00
IUUC-Mlu-068155	Myotis lucifugus	51.27	3.00e-126	444.00
IUUC-Nle-069964	Nomascus leucogenys	50.95	2.00e-125	441.00
IUUC-Opr-070925	Ochotona princeps	40.73	7.00e-49	187.00
IUUC-Ont-071317	Oreochromis niloticus	50.32	6.00e-120	423.00
IUUC-Oan-072952	Ornithorhynchus anatinus	49.37	3.00e-123	434.00
IUUC-Ocu-073913	Oryctolagus cuniculus	50.21	6.00e-125	439.00
IUUC-Ola-087024	Oryzias latipes	49.79	1.00e-121	429.00
IUUC-Oga-087945	Otolemur garnettii	50.21	2.00e-125	441.00
IUUC-Oar-089854	Ovis aries	50.00	3.00e-122	431.00
IUUC-Ptr-091486	Pan troglodytes	50.85	3.00e-125	441.00
IUUC-Pan-091738	Papio anubis	50.74	9.00e-125	439.00
IUUC-Psi-093953	Pelodiscus sinensis	48.95	8.00e-122	429.00
IUUC-Pma-094560	Petromyzon marinus	49.69	4.00e-121	427.00
IUUC-Pfo-097222	Poecilia formosa	50.85	1.00e-120	425.00
IUUC-Pab-098778	Pongo abelii	50.21	1.00e-117	415.00
IUUC-Pca-100852	Procavia capensis	48.31	2.00e-112	398.00
IUUC-Pva-103130	Pteropus vampyrus	59.52	2.00e-54	206.00
IUUC-Rno-105848	Rattus norvegicus	52.86	5.00e-110	390.00
IUUC-Sha-106750	Sarcophilus harrisii	49.37	4.00e-122	431.00
IUUC-Sar-113749	Sorex araneus	45.34	4.00e-102	364.00
IUUC-Ssc-115691	Sus scrofa	49.89	3.00e-119	421.00
IUUC-Tgu-117365	Taeniopygia guttata	53.62	7.00e-116	409.00
IUUC-Tru-118335	Takifugu rubripes	49.35	6.00e-118	416.00
IUUC-Tsy-118973	Tarsius syrichta	46.89	7.00e-71	260.00
IUUC-Tni-120881	Tetraodon nigroviridis	48.71	6.00e-120	423.00
IUUC-Tbe-127976	Tupaia belangeri	47.09	6.00e-82	296.00
IUUC-Ttr-128472	Tursiops truncatus	48.52	2.00e-116	411.00
IUUC-Xtr-132621	Xenopus tropicalis	54.34	1.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence