iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-33	113.7	327	363
UBD/Beta-Prp	5.90e-44	150.4	278	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH   + ++a+ +  t ++s+s+D  ik+WD  tg++
   Q: 327  GHRQAIKDIAWnNRgTNFLSASYDRYIKLWDAETGDV 363
           899********733699**************999986 PP

UBD/Beta-Prp

   S: 87   vhtlkghedsvlslsfspsg.dklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +ht++gh++ + s++++p++ + l+sGs d  +++w++  ++ c++ t+sgh++++  ++++  g  + s+s+Dr ++lWd +tg+++ ++t    ++
   Q: 278  IHTWSGHNKGISSIRWFPKTaHLLLSGSMDCRVKLWEVyGERRCIR-TFSGHRQAIKDIAWNNRGTNFLSASYDRYIKLWDAETGDVVSRFTT--RKM 372
           89****************666****************935677887.********************************************86..666 PP
   S: 183  vyslsfdsng...kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
             +++f+++      +v+g  d++++ wd ++g++v+++  h   v+ + f +++ r+v++s+D+s riW  +    +k ++ +  ++++  +l +++
   Q: 373  PFCVKFHPDNskqHLFVAGTSDKKIICWDTRSGDIVQEYDRHLGSVSTITFVDDNRRFVTTSDDKSMRIWEWDIPVDMKYIADPTMHSMPAVTLAPNG 470
           7799999988887899******************************************************9999999********************* PP
   S: 278  nvlvlgsedskvniwk 293
           + ++  s d+k+ i++
   Q: 471  KWMACQSLDNKIVIFS 486
           *************997 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MLGLQSYASS SDEESDHADA ATATTNSEPS APIPDHLLPV DKTHSLSKSI AVCAAPTVVP 60
LGASAVPRTL DPTLKEVTYN PRYEEMYAPV KGPEHPDLTM QQRAPRNTLA GYVEKAHINA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAACAGATGG CACGCACCAT CCCTAGTTTT GATAGATATA TATTTATGTT TTTGTTACTT 60
TTACTGAAGC AACTAATGAT AAACGCAAAC GTGTAGACGA ATGGAAATAT CCATTAACGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR032847--PRPF17
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005681--C:spliceosomal complex
GO:0003723--F:RNA binding
GO:0000398--P:mRNA splicing, via spliceosome

KEGG

dme:Dmel_CG6015

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000473	Aegilops tauschii	46.39	7.00e-140	489.00
IUUC-Aml-002243	Ailuropoda melanoleuca	58.85	5.00e-144	503.00
IUUC-Atr-002502	Amborella trichopoda	44.86	7.00e-143	499.00
IUUC-Apl-003885	Anas platyrhynchos	65.17	0.00e+00	735.00
IUUC-Aca-004854	Anolis carolinensis	48.15	1.00e-144	505.00
IUUC-Aly-006158	Arabidopsis lyrata	45.54	8.00e-146	509.00
IUUC-Ath-007474	Arabidopsis thaliana	45.60	3.00e-144	504.00
IUUC-Ago-007726	Ashbya gossypii	34.53	4.00e-72	264.00
IUUC-Acl-008220	Aspergillus clavatus	42.70	3.00e-123	434.00
IUUC-Afl-008473	Aspergillus flavus	42.22	4.00e-119	421.00
IUUC-Afu-008773	Aspergillus fumigatus	41.90	4.00e-122	431.00
IUUC-Ani-009323	Aspergillus nidulans	39.84	9.00e-105	373.00
IUUC-Ang-009851	Aspergillus niger	40.73	2.00e-122	431.00
IUUC-Aor-009950	Aspergillus oryzae	42.22	4.00e-119	421.00
IUUC-Ate-010372	Aspergillus terreus	42.32	1.00e-124	439.00
IUUC-Ame-011660	Astyanax mexicanus	62.27	0.00e+00	735.00
IUUC-Bgr-012230	Blumeria graminis	40.26	8.00e-113	399.00
IUUC-Bta-012568	Bos taurus	62.36	0.00e+00	727.00
IUUC-Bci-013646	Botrytis cinerea	38.98	2.00e-110	391.00
IUUC-Bdi-014199	Brachypodium distachyon	46.49	1.00e-140	492.00
IUUC-Bol-015695	Brassica oleracea	46.70	7.00e-148	516.00
IUUC-Bra-017923	Brassica rapa	44.56	1.00e-149	522.00
IUUC-Cel-018535	Caenorhabditis elegans	47.26	1.00e-170	592.00
IUUC-Cja-019071	Callithrix jacchus	62.25	0.00e+00	724.00
IUUC-Cfa-020559	Canis familiaris	62.41	0.00e+00	725.00
IUUC-Cpo-022356	Cavia porcellus	62.41	0.00e+00	725.00
IUUC-Cre-022594	Chlamydomonas reinhardtii	38.73	6.00e-68	249.00
IUUC-Csa-023125	Chlorocebus sabaeus	62.41	0.00e+00	726.00
IUUC-Cho-024676	Choloepus hoffmanni	60.04	0.00e+00	673.00
IUUC-Cin-025229	Ciona intestinalis	63.69	0.00e+00	715.00
IUUC-Csv-025868	Ciona savignyi	65.96	3.00e-37	144.00
IUUC-Cgl-026739	Colletotrichum gloeosporioides	48.99	2.00e-97	348.00
IUUC-Cne-026885	Cryptococcus neoformans	47.15	1.00e-135	476.00
IUUC-Dre-027631	Danio rerio	63.90	0.00e+00	749.00
IUUC-Dno-029815	Dasypus novemcinctus	57.61	0.00e+00	674.00
IUUC-Dor-030978	Dipodomys ordii	62.53	1.00e-171	595.00
IUUC-Dse-031520	Dothistroma septosporum	44.69	1.00e-91	329.00
IUUC-Ete-032866	Echinops telfairi	60.91	0.00e+00	704.00
IUUC-Eca-033384	Equus caballus	62.41	0.00e+00	721.00
IUUC-Eeu-034471	Erinaceus europaeus	52.93	5.00e-154	536.00
IUUC-Fca-035727	Felis catus	62.36	0.00e+00	728.00
IUUC-Fal-036774	Ficedula albicollis	65.69	0.00e+00	748.00
IUUC-Fox-037951	Fusarium oxysporum	38.75	8.00e-111	393.00
IUUC-Fso-038287	Fusarium solani	50.88	5.00e-107	380.00
IUUC-Gmo-039670	Gadus morhua	61.62	0.00e+00	726.00
IUUC-Ggr-039764	Gaeumannomyces graminis	38.08	8.00e-107	380.00
IUUC-Gga-040293	Gallus gallus	65.55	0.00e+00	746.00
IUUC-Gac-042159	Gasterosteus aculeatus	60.90	0.00e+00	749.00
IUUC-Gma-044299	Glycine max	56.89	2.00e-125	441.00
IUUC-Ggo-044864	Gorilla gorilla	62.59	0.00e+00	727.00
IUUC-Hsa-046602	Homo sapiens	62.59	0.00e+00	727.00
IUUC-Hvu-047431	Hordeum vulgare	30.36	7.00e-40	157.00
IUUC-Itr-047985	Ictidomys tridecemlineatus	67.07	1.00e-175	608.00
IUUC-Kpa-049318	Komagataella pastoris	43.10	1.00e-89	323.00
IUUC-Lch-049796	Latimeria chalumnae	56.17	0.00e+00	628.00
IUUC-Lpe-051153	Leersia perrieri	47.55	8.00e-142	496.00
IUUC-Loc-052467	Lepisosteus oculatus	63.47	0.00e+00	751.00
IUUC-Lma-053107	Leptosphaeria maculans	45.14	2.00e-106	378.00
IUUC-Laf-053787	Loxodonta africana	61.96	0.00e+00	740.00
IUUC-Mcc-055706	Macaca mulatta	62.41	0.00e+00	726.00
IUUC-Meu-056757	Macropus eugenii	58.01	3.00e-141	494.00
IUUC-Mor-057079	Magnaporthe oryzae	36.25	6.00e-104	370.00
IUUC-Mpo-057533	Magnaporthe poae	49.71	1.00e-106	379.00
IUUC-Mtr-057950	Medicago truncatula	54.94	1.00e-123	436.00
IUUC-Mla-058910	Melampsora laricipopulina	43.81	4.00e-136	477.00
IUUC-Mga-059366	Meleagris gallopavo	65.55	0.00e+00	744.00
IUUC-Mvi-060349	Microbotryum violaceum	44.13	8.00e-133	466.00
IUUC-Mmr-061209	Microcebus murinus	62.23	0.00e+00	746.00
IUUC-Mdo-062118	Monodelphis domestica	62.55	0.00e+00	753.00
IUUC-Mmu-063173	Mus musculus	62.59	0.00e+00	728.00
IUUC-Mac-065080	Musa acuminata	48.65	1.00e-145	508.00
IUUC-Mpu-066659	Mustela putorius furo	62.36	0.00e+00	729.00
IUUC-Mlu-067029	Myotis lucifugus	65.35	0.00e+00	719.00
IUUC-Nfi-068334	Neosartorya fischeri	42.09	3.00e-123	434.00
IUUC-Ncr-068675	Neurospora crassa	46.55	4.00e-94	337.00
IUUC-Nle-070113	Nomascus leucogenys	62.04	0.00e+00	723.00
IUUC-Opr-070685	Ochotona princeps	58.21	0.00e+00	687.00
IUUC-Ont-071680	Oreochromis niloticus	62.54	0.00e+00	741.00
IUUC-Oan-073573	Ornithorhynchus anatinus	64.38	0.00e+00	691.00
IUUC-Ocu-074074	Oryctolagus cuniculus	62.04	0.00e+00	746.00
IUUC-Oba-075625	Oryza barthii	47.17	3.00e-143	500.00
IUUC-Obr-076510	Oryza brachyantha	47.27	8.00e-142	496.00
IUUC-Ogl-077275	Oryza glaberrima	47.17	3.00e-143	500.00
IUUC-Ogu-078563	Oryza glumaepatula	47.17	3.00e-143	501.00
IUUC-Oin-079898	Oryza indica	56.43	8.00e-125	439.00
IUUC-Olo-081080	Oryza longistaminata	48.17	2.00e-137	481.00
IUUC-Ome-081794	Oryza meridionalis	31.78	3.00e-31	128.00
IUUC-Oni-083121	Oryza nivara	47.17	3.00e-143	501.00
IUUC-Opu-083329	Oryza punctata	47.26	5.00e-143	500.00
IUUC-Oru-084807	Oryza rufipogon	46.27	5.00e-124	437.00
IUUC-Osa-086039	Oryza sativa	47.27	7.00e-144	503.00
IUUC-Ola-087149	Oryzias latipes	63.17	0.00e+00	743.00
IUUC-Olu-087627	Ostreococcus lucimarinus	41.75	5.00e-116	410.00
IUUC-Oga-088359	Otolemur garnettii	62.41	0.00e+00	726.00
IUUC-Oar-089390	Ovis aries	62.36	0.00e+00	726.00
IUUC-Ptr-090894	Pan troglodytes	62.59	0.00e+00	727.00
IUUC-Pan-092476	Papio anubis	62.41	0.00e+00	726.00
IUUC-Psi-093527	Pelodiscus sinensis	63.43	0.00e+00	693.00
IUUC-Pno-094771	Phaeosphaeria nodorum	43.98	7.00e-105	373.00
IUUC-Ppa-095386	Physcomitrella patens	46.37	6.00e-147	513.00
IUUC-Pfo-096139	Poecilia formosa	62.98	0.00e+00	744.00
IUUC-Pab-097838	Pongo abelii	61.55	0.00e+00	631.00
IUUC-Pop-098945	Populus trichocarpa	45.42	3.00e-143	501.00
IUUC-Pca-100876	Procavia capensis	52.36	2.00e-172	598.00
IUUC-Ppe-101777	Prunus persica	44.46	2.00e-139	488.00
IUUC-Pva-102418	Pteropus vampyrus	62.23	0.00e+00	724.00
IUUC-Pgr-103456	Puccinia graminis	46.96	3.00e-149	521.00
IUUC-Ptt-103731	Puccinia triticina	43.07	9.00e-137	479.00
IUUC-Pte-104386	Pyrenophora teres	50.75	9.00e-102	362.00
IUUC-Pyt-104560	Pyrenophora triticirepentis	51.05	4.00e-102	363.00
IUUC-Rno-105694	Rattus norvegicus	59.49	0.00e+00	678.00
IUUC-Sce-106339	Saccharomyces cerevisiae	38.24	2.00e-74	272.00
IUUC-Sha-106709	Sarcophilus harrisii	62.18	0.00e+00	746.00
IUUC-Sja-107817	Schizosaccharomyces japonicus	39.96	3.00e-120	424.00
IUUC-Spo-108331	Schizosaccharomyces pombe	40.64	3.00e-117	414.00
IUUC-Ssl-108530	Sclerotinia sclerotiorum	37.97	2.00e-96	345.00
IUUC-Smo-108778	Selaginella moellendorffii	43.05	5.00e-127	447.00
IUUC-Sit-110446	Setaria italica	47.18	8.00e-142	496.00
IUUC-Sly-111330	Solanum lycopersicum	46.27	3.00e-143	501.00
IUUC-Stu-112610	Solanum tuberosum	46.00	1.00e-142	498.00
IUUC-Sar-113065	Sorex araneus	44.18	2.00e-71	261.00
IUUC-Sbi-114005	Sorghum bicolor	46.31	3.00e-140	491.00
IUUC-Sre-114988	Sporisorium reilianum	46.56	3.00e-146	511.00
IUUC-Ssc-115760	Sus scrofa	62.36	0.00e+00	727.00
IUUC-Tgu-116493	Taeniopygia guttata	65.55	0.00e+00	753.00
IUUC-Tru-118489	Takifugu rubripes	63.17	0.00e+00	739.00
IUUC-Tsy-119332	Tarsius syrichta	62.41	0.00e+00	747.00
IUUC-Tni-120202	Tetraodon nigroviridis	61.21	0.00e+00	690.00
IUUC-Tca-121429	Theobroma cacao	43.00	5.00e-142	497.00
IUUC-Tre-122162	Trichoderma reesei	39.34	3.00e-110	391.00
IUUC-Tvi-122500	Trichoderma virens	38.26	1.00e-108	385.00
IUUC-Tae-125557	Triticum aestivum	46.11	2.00e-139	488.00
IUUC-Tur-126554	Triticum urartu	46.10	2.00e-138	484.00
IUUC-Tme-126919	Tuber melanosporum	42.76	2.00e-132	465.00
IUUC-Tbe-127968	Tupaia belangeri	57.82	0.00e+00	686.00
IUUC-Ttr-129215	Tursiops truncatus	62.18	0.00e+00	721.00
IUUC-Uma-129622	Ustilago maydis	45.99	1.00e-146	513.00
IUUC-Vda-129750	Verticillium dahliae	40.11	2.00e-110	392.00
IUUC-Vpa-130617	Vicugna pacos	63.12	0.00e+00	685.00
IUUC-Vvi-131238	Vitis vinifera	55.36	2.00e-124	438.00
IUUC-Xtr-131865	Xenopus tropicalis	64.97	0.00e+00	729.00
IUUC-Xma-133627	Xiphophorus maculatus	62.62	0.00e+00	739.00
IUUC-Yli-134390	Yarrowia lipolytica	43.03	6.00e-109	387.00
IUUC-Zma-135925	Zea mays	47.26	3.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence