iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003812

Ensembl Protein ID

ENSAPLP00000004235.1

UniProt Accession

U3IAG4; U3IAG4_ANAPL

Genbank Protein ID

ENSAPLP00000004235

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01068206

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004645.1	ENSAPLT00000004847.1	ENSAPLP00000004235.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	4.90e-22	77.4	453	512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let+ vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q++ l+k+ + l+d +++s
   Q: 453  QEEDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLAVQLAYLLKDQQNLEDLGRNS 512
           79***************************************************9988876 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MSSKVQSRPA ENGEHPRSKM ENGTDGGAAP TLSTYTPEEM VQQMKELITE NNELKEAMKL 60
HNQAMKERYE ELSIWREKQK EEREFYETKF KEAKQCLLAK CVENEQLQQQ LQSLKEREEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGCA AGGTGCAGAG CCGTCCTGCG GAAAATGGAG AGCATCCCAG GAGCAAAATG 60
GAAAACGGGA CAGACGGTGG GGCTGCCCCC ACCCTCAGCA CATACACACC TGAAGAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	55.07	2.00e-144	505.00
IUUC-Aca-004625	Anolis carolinensis	60.31	4.00e-174	603.00
IUUC-Aly-005781	Arabidopsis lyrata	45.00	1.40e-01	30.40
IUUC-Ame-011116	Astyanax mexicanus	46.15	1.00e-53	204.00
IUUC-Bta-013240	Bos taurus	56.38	9.00e-160	556.00
IUUC-Cja-019911	Callithrix jacchus	56.83	6.00e-155	540.00
IUUC-Cfa-020330	Canis familiaris	57.50	3.00e-147	514.00
IUUC-Cpo-021753	Cavia porcellus	54.91	5.00e-149	520.00
IUUC-Csa-023662	Chlorocebus sabaeus	57.71	2.00e-155	542.00
IUUC-Cho-024574	Choloepus hoffmanni	45.69	4.00e-72	264.00
IUUC-Dre-027720	Danio rerio	41.54	3.00e-91	328.00
IUUC-Dno-029079	Dasypus novemcinctus	56.99	6.00e-142	497.00
IUUC-Dor-030890	Dipodomys ordii	54.03	6.00e-151	527.00
IUUC-Dme-032072	Drosophila melanogaster	28.63	9.00e-06	44.30
IUUC-Ete-032568	Echinops telfairi	56.14	2.00e-138	485.00
IUUC-Eca-033528	Equus caballus	56.20	4.00e-151	527.00
IUUC-Eeu-035219	Erinaceus europaeus	53.85	2.00e-146	512.00
IUUC-Fca-035852	Felis catus	56.73	2.00e-148	518.00
IUUC-Fal-036862	Ficedula albicollis	83.33	0.00e+00	847.00
IUUC-Gmo-038735	Gadus morhua	38.53	5.00e-72	264.00
IUUC-Gga-040939	Gallus gallus	86.14	0.00e+00	911.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.39	7.00e-90	324.00
IUUC-Ggo-045034	Gorilla gorilla	51.38	1.00e-136	479.00
IUUC-Hsa-046624	Homo sapiens	57.73	6.00e-157	547.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	51.19	3.00e-139	488.00
IUUC-Lch-049720	Latimeria chalumnae	48.14	9.00e-79	286.00
IUUC-Loc-052185	Lepisosteus oculatus	45.36	7.00e-108	384.00
IUUC-Laf-054079	Loxodonta africana	57.27	9.00e-145	506.00
IUUC-Mcc-055674	Macaca mulatta	58.48	6.00e-156	543.00
IUUC-Meu-056769	Macropus eugenii	71.95	2.00e-63	236.00
IUUC-Mga-060203	Meleagris gallopavo	84.80	0.00e+00	847.00
IUUC-Mmr-061492	Microcebus murinus	57.49	8.00e-149	520.00
IUUC-Mdo-063051	Monodelphis domestica	57.39	9.00e-164	570.00
IUUC-Mmu-063409	Mus musculus	54.24	5.00e-153	534.00
IUUC-Mpu-065907	Mustela putorius furo	53.55	9.00e-146	509.00
IUUC-Mlu-066957	Myotis lucifugus	58.87	1.00e-147	515.00
IUUC-Nle-069973	Nomascus leucogenys	57.22	2.00e-152	531.00
IUUC-Opr-071049	Ochotona princeps	51.20	3.00e-133	468.00
IUUC-Ont-071915	Oreochromis niloticus	42.99	2.00e-95	342.00
IUUC-Oan-072965	Ornithorhynchus anatinus	57.46	9.00e-163	566.00
IUUC-Ocu-074029	Oryctolagus cuniculus	51.77	3.00e-121	428.00
IUUC-Ola-087019	Oryzias latipes	39.13	5.00e-85	308.00
IUUC-Oga-088613	Otolemur garnettii	56.27	3.00e-152	531.00
IUUC-Oar-090386	Ovis aries	56.03	6.00e-159	553.00
IUUC-Ptr-091619	Pan troglodytes	57.39	5.00e-155	540.00
IUUC-Pan-092178	Papio anubis	57.78	7.00e-155	540.00
IUUC-Psi-093214	Pelodiscus sinensis	66.38	0.00e+00	649.00
IUUC-Pfo-096901	Poecilia formosa	41.80	2.00e-87	315.00
IUUC-Pab-097560	Pongo abelii	62.64	2.00e-108	385.00
IUUC-Pca-100853	Procavia capensis	47.63	2.00e-61	229.00
IUUC-Pva-102255	Pteropus vampyrus	53.77	2.00e-134	472.00
IUUC-Rno-105812	Rattus norvegicus	54.64	4.00e-153	534.00
IUUC-Sha-107225	Sarcophilus harrisii	63.34	4.00e-116	410.00
IUUC-Sar-113736	Sorex araneus	57.98	1.00e-89	323.00
IUUC-Ssc-115422	Sus scrofa	56.28	5.00e-155	540.00
IUUC-Tgu-116924	Taeniopygia guttata	78.20	0.00e+00	748.00
IUUC-Tru-117695	Takifugu rubripes	41.16	2.00e-86	312.00
IUUC-Tsy-119090	Tarsius syrichta	52.89	2.00e-77	282.00
IUUC-Tni-120645	Tetraodon nigroviridis	40.51	4.00e-89	321.00
IUUC-Tbe-127970	Tupaia belangeri	66.20	3.00e-92	332.00
IUUC-Ttr-129244	Tursiops truncatus	55.34	3.00e-150	524.00
IUUC-Vpa-130313	Vicugna pacos	56.03	5.00e-145	507.00
IUUC-Xtr-132115	Xenopus tropicalis	43.43	4.00e-102	364.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence