iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092509

Ensembl Protein ID

ENSPANP00000011575.1

UniProt Accession

A0A096NF82; A0A096NF82_PAPAN

Protein Name

Uncharacterized protein

Gene Name

UBE3A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000018034.1	ENSPANT00000027937.1	ENSPANP00000011575.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.60e-67	226.6	558	797

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f+y+e+ k  ++ np+s+    e +  F+++G++lg+a++++ +ld+
   Q: 558  PADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWF-NPSSF----ETEGQFTLIGIVLGLAIYNNCILDV 641
           689******************************************998888876.88888....789********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.lgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl + +p ly+slk ++e+ e ++e+  + +tf++s++  +g+   ++Lk++G++ip+tneN++e+v+l+ 
   Q: 642  HFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEY-EGNVEDD-MMITFQISQTDlFGNPMMYDLKENGDKIPITNENRKEFVNLYS 728
           *************************************.7799986.99***9665444******************************* PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspai 246
           +y+l++++++q++afr+Gf+ v +++ l  lF++ee+ellicG++++d+++l+++t+y+ggyt+ds  i
   Q: 729  DYILNKSVEKQFKAFRRGFHMVTNESpLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLI 797
           ***********************99934558**********************************9776 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MEKLHQCYWK SGEPQSDDIE ASRIDYSQAA LSVRKRAAAK HLIERYYHQL TEGCGNEACT 60
NEFCASCPTF LRMDNNAAAI KALELYKINA KLCDPHPSKK GASSAYLENS KGAPNNSCSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTAAAAATC TGTAAGAGCC TGATTTTAGA ATTCACCAGC TCCTCAGAAG TTTGGCGAAA 60
TATGGTATGT TTTTGTTTTA TTTTTTGGAA TTCGTATTGC ATGTGTATCT TAATGTCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0030521--P:androgen receptor signaling pathway
GO:0001541--P:ovarian follicle development
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0060736--P:prostate gland growth
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042752--P:regulation of circadian rhythm
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035037--P:sperm entry
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002214	Ailuropoda melanoleuca	97.79	0.00e+00	1452.00
IUUC-Apl-003742	Anas platyrhynchos	88.99	0.00e+00	1416.00
IUUC-Aca-004873	Anolis carolinensis	91.28	0.00e+00	1431.00
IUUC-Ame-011166	Astyanax mexicanus	86.23	0.00e+00	1281.00
IUUC-Bta-013286	Bos taurus	95.22	0.00e+00	1411.00
IUUC-Cja-019707	Callithrix jacchus	97.87	0.00e+00	1512.00
IUUC-Cfa-020154	Canis familiaris	95.97	0.00e+00	1450.00
IUUC-Cpo-021292	Cavia porcellus	97.27	0.00e+00	1443.00
IUUC-Csa-023378	Chlorocebus sabaeus	98.48	0.00e+00	1499.00
IUUC-Cho-025059	Choloepus hoffmanni	95.97	0.00e+00	1361.00
IUUC-Cin-025643	Ciona intestinalis	42.45	4.00e-166	578.00
IUUC-Csv-026282	Ciona savignyi	42.19	1.00e-159	556.00
IUUC-Dre-027901	Danio rerio	85.83	0.00e+00	1271.00
IUUC-Dno-029320	Dasypus novemcinctus	95.48	0.00e+00	1454.00
IUUC-Dor-030756	Dipodomys ordii	95.18	0.00e+00	743.00
IUUC-Dme-032035	Drosophila melanogaster	39.97	3.00e-126	446.00
IUUC-Eca-033843	Equus caballus	97.52	0.00e+00	1412.00
IUUC-Eeu-035109	Erinaceus europaeus	95.81	0.00e+00	1405.00
IUUC-Fca-036344	Felis catus	93.97	0.00e+00	1447.00
IUUC-Fal-036747	Ficedula albicollis	88.99	0.00e+00	1417.00
IUUC-Gmo-038840	Gadus morhua	60.93	0.00e+00	962.00
IUUC-Gga-040399	Gallus gallus	88.86	0.00e+00	1415.00
IUUC-Gac-041933	Gasterosteus aculeatus	82.48	0.00e+00	1217.00
IUUC-Ggo-044804	Gorilla gorilla	98.37	0.00e+00	1519.00
IUUC-Hsa-045727	Homo sapiens	98.37	0.00e+00	1519.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	93.62	0.00e+00	1359.00
IUUC-Lch-050197	Latimeria chalumnae	89.00	0.00e+00	1360.00
IUUC-Loc-052743	Lepisosteus oculatus	86.90	0.00e+00	1360.00
IUUC-Laf-053615	Loxodonta africana	96.74	0.00e+00	1441.00
IUUC-Mcc-054934	Macaca mulatta	97.99	0.00e+00	1499.00
IUUC-Meu-056061	Macropus eugenii	89.15	0.00e+00	1273.00
IUUC-Mga-059271	Meleagris gallopavo	90.93	0.00e+00	1403.00
IUUC-Mmr-061288	Microcebus murinus	96.61	0.00e+00	1488.00
IUUC-Mdo-062975	Monodelphis domestica	93.60	0.00e+00	1434.00
IUUC-Mmu-063674	Mus musculus	93.43	0.00e+00	1405.00
IUUC-Mpu-066568	Mustela putorius furo	96.23	0.00e+00	1474.00
IUUC-Mlu-067522	Myotis lucifugus	86.77	0.00e+00	1330.00
IUUC-Nle-069505	Nomascus leucogenys	98.37	0.00e+00	1519.00
IUUC-Opr-070570	Ochotona princeps	88.47	0.00e+00	1298.00
IUUC-Ont-071527	Oreochromis niloticus	83.49	0.00e+00	1285.00
IUUC-Oan-073446	Ornithorhynchus anatinus	88.93	0.00e+00	1045.00
IUUC-Ocu-074922	Oryctolagus cuniculus	93.64	0.00e+00	1456.00
IUUC-Ola-086996	Oryzias latipes	85.81	0.00e+00	1315.00
IUUC-Oga-088261	Otolemur garnettii	98.69	0.00e+00	1469.00
IUUC-Oar-090024	Ovis aries	95.22	0.00e+00	1411.00
IUUC-Ptr-090455	Pan troglodytes	98.37	0.00e+00	1519.00
IUUC-Psi-092974	Pelodiscus sinensis	89.10	0.00e+00	1385.00
IUUC-Pma-094643	Petromyzon marinus	70.20	0.00e+00	1098.00
IUUC-Pfo-096905	Poecilia formosa	83.42	0.00e+00	1280.00
IUUC-Pab-097840	Pongo abelii	96.99	0.00e+00	1432.00
IUUC-Pca-100869	Procavia capensis	96.35	0.00e+00	1429.00
IUUC-Pva-103040	Pteropus vampyrus	78.40	3.00e-163	568.00
IUUC-Rno-105453	Rattus norvegicus	93.69	0.00e+00	1409.00
IUUC-Sha-107651	Sarcophilus harrisii	93.60	0.00e+00	1434.00
IUUC-Sar-113293	Sorex araneus	96.87	0.00e+00	1432.00
IUUC-Ssc-115979	Sus scrofa	97.00	0.00e+00	1436.00
IUUC-Tgu-116901	Taeniopygia guttata	88.99	0.00e+00	1416.00
IUUC-Tru-118368	Takifugu rubripes	83.88	0.00e+00	1280.00
IUUC-Tsy-119516	Tarsius syrichta	94.11	0.00e+00	1357.00
IUUC-Tni-120143	Tetraodon nigroviridis	81.50	0.00e+00	1272.00
IUUC-Tbe-127484	Tupaia belangeri	92.44	0.00e+00	1106.00
IUUC-Ttr-129078	Tursiops truncatus	96.87	0.00e+00	1413.00
IUUC-Vpa-130312	Vicugna pacos	96.90	0.00e+00	1293.00
IUUC-Xtr-132881	Xenopus tropicalis	89.76	0.00e+00	1367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence