iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssl-108595

Ensembl Protein ID

EDO02807

UniProt Accession

A7EIZ1; NACA_SCLS1

Genbank Protein ID

EDO02807.1

Protein Name

Nascent polypeptide-associated complex subunit alpha; Alpha-NAC

Genbank Nucleotide ID

CH476626

Gene Name

egd2; SS1G_05284

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SS1G_05284	EDO02807	EDO02807

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	50.00	9.00e-16	78.20	IUUC-Sce-106371
UBD/Alpha-Helix/UBA	46.82	7.00e-28	118.00	IUUC-Spo-108121

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sclerotinia sclerotiorum

Functional Description
(View)

Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).

Protein Sequence
(Fasta)

MSNPRIEELP DNEEPTKQQV TAEDEGSDSS DSEGEGEVES GIPAGAGAVV HSRNEKKARK 60
SIAKLGLTRV PGITRVTLRR PKNILFVINN PEVYKSPTSN TYIVFGEAKI EDLNSQAQAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAACC CACGTATTGA GGAACTCCCA GATAACGAGG AGCCAACCAA GCAACAAGTT 60
ACCGCAGAAG ATGAGGGATC CGATAGCTCT GACTCCGAGG GAGAGGGAGA GGTAGAGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016641--EGD2/NACA
IPR002715--Nas_poly-pep-assoc_cplx_dom

PROSITE

PS51151--NAC_AB

Pfam

PF01849--NAC

SMART

SM01407--NAC

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0015031--P:protein transport

KEGG

ssl:SS1G_05284

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001167	Aegilops tauschii	57.69	1.00e-16	77.00
IUUC-Aml-002185	Ailuropoda melanoleuca	47.56	3.00e-26	112.00
IUUC-Atr-002586	Amborella trichopoda	41.18	2.00e-10	57.00
IUUC-Apl-003190	Anas platyrhynchos	65.15	1.00e-21	93.20
IUUC-Aca-005265	Anolis carolinensis	71.88	1.00e-24	103.00
IUUC-Aly-006488	Arabidopsis lyrata	45.75	1.00e-25	107.00
IUUC-Ath-007378	Arabidopsis thaliana	38.56	9.00e-16	74.70
IUUC-Ago-007936	Ashbya gossypii	48.65	2.00e-17	79.70
IUUC-Acl-008036	Aspergillus clavatus	65.77	3.00e-34	135.00
IUUC-Afl-008462	Aspergillus flavus	61.68	1.00e-52	196.00
IUUC-Afu-008832	Aspergillus fumigatus	56.76	2.00e-30	123.00
IUUC-Ani-009246	Aspergillus nidulans	65.79	2.00e-35	139.00
IUUC-Ang-009808	Aspergillus niger	63.06	2.00e-33	133.00
IUUC-Aor-009972	Aspergillus oryzae	61.68	1.00e-52	196.00
IUUC-Ame-011674	Astyanax mexicanus	71.88	1.00e-24	103.00
IUUC-Bgr-012162	Blumeria graminis	66.67	8.00e-33	130.00
IUUC-Bta-012508	Bos taurus	71.88	1.00e-24	104.00
IUUC-Bci-013643	Botrytis cinerea	92.99	4.00e-63	231.00
IUUC-Bdi-014854	Brachypodium distachyon	57.69	4.00e-16	75.50
IUUC-Bol-015681	Brassica oleracea	55.56	2.00e-16	77.00
IUUC-Bra-017540	Brassica rapa	39.87	3.00e-20	89.40
IUUC-Cel-018111	Caenorhabditis elegans	47.56	5.00e-34	134.00
IUUC-Cja-019846	Callithrix jacchus	45.12	2.00e-27	116.00
IUUC-Cfa-020429	Canis familiaris	71.88	8.00e-25	104.00
IUUC-Cpo-021659	Cavia porcellus	46.34	1.00e-27	116.00
IUUC-Cre-022679	Chlamydomonas reinhardtii	47.34	2.00e-32	129.00
IUUC-Csa-023260	Chlorocebus sabaeus	46.34	5.00e-27	115.00
IUUC-Cho-024869	Choloepus hoffmanni	72.97	1.00e-10	57.00
IUUC-Cin-025166	Ciona intestinalis	50.88	1.00e-33	134.00
IUUC-Csv-026284	Ciona savignyi	45.75	2.00e-23	98.60
IUUC-Cgl-026520	Colletotrichum gloeosporioides	72.81	5.00e-38	148.00
IUUC-Cne-026920	Cryptococcus neoformans	64.47	2.00e-25	105.00
IUUC-Cme-027301	Cyanidioschyzon merolae	42.26	3.00e-22	96.30
IUUC-Dre-028709	Danio rerio	71.88	5.00e-24	104.00
IUUC-Dno-029367	Dasypus novemcinctus	44.51	3.00e-27	115.00
IUUC-Dor-030962	Dipodomys ordii	71.88	1.00e-24	103.00
IUUC-Dme-032061	Drosophila melanogaster	48.78	1.00e-24	104.00
IUUC-Ete-032965	Echinops telfairi	67.65	2.00e-24	103.00
IUUC-Eca-034049	Equus caballus	70.31	6.00e-24	101.00
IUUC-Eeu-034673	Erinaceus europaeus	71.88	1.00e-24	104.00
IUUC-Fca-035429	Felis catus	47.56	8.00e-27	114.00
IUUC-Fal-037006	Ficedula albicollis	71.88	1.00e-24	103.00
IUUC-Fox-037704	Fusarium oxysporum	69.16	5.00e-54	201.00
IUUC-Fso-038247	Fusarium solani	66.98	2.00e-56	209.00
IUUC-Gmo-039002	Gadus morhua	51.22	1.00e-33	133.00
IUUC-Ggr-039888	Gaeumannomyces graminis	71.93	2.00e-39	153.00
IUUC-Gga-040237	Gallus gallus	71.88	1.00e-24	103.00
IUUC-Gac-041800	Gasterosteus aculeatus	71.88	4.00e-24	103.00
IUUC-Gma-043275	Glycine max	47.06	6.00e-29	118.00
IUUC-Ggo-045163	Gorilla gorilla	44.51	3.00e-33	132.00
IUUC-Hsa-045795	Homo sapiens	71.88	2.00e-23	103.00
IUUC-Hvu-047376	Hordeum vulgare	47.06	2.00e-25	106.00
IUUC-Itr-048152	Ictidomys tridecemlineatus	71.88	1.00e-24	104.00
IUUC-Kpa-049166	Komagataella pastoris	53.42	2.00e-18	83.20
IUUC-Lch-050076	Latimeria chalumnae	71.88	8.00e-25	104.00
IUUC-Lpe-051258	Leersia perrieri	46.41	1.00e-25	107.00
IUUC-Loc-052292	Lepisosteus oculatus	71.88	3.00e-24	102.00
IUUC-Lma-053293	Leptosphaeria maculans	67.54	9.00e-36	140.00
IUUC-Laf-054393	Loxodonta africana	45.73	6.00e-34	134.00
IUUC-Mcc-054632	Macaca mulatta	71.88	2.00e-23	103.00
IUUC-Meu-056242	Macropus eugenii	71.88	7.00e-25	104.00
IUUC-Mor-057099	Magnaporthe oryzae	71.05	2.00e-38	149.00
IUUC-Mpo-057543	Magnaporthe poae	66.99	1.00e-30	123.00
IUUC-Mtr-058112	Medicago truncatula	42.60	6.00e-30	121.00
IUUC-Mla-059166	Melampsora laricipopulina	45.56	1.00e-25	107.00
IUUC-Mga-059406	Meleagris gallopavo	50.60	1.00e-32	130.00
IUUC-Mvi-060390	Microbotryum violaceum	34.55	1.00e-21	93.20
IUUC-Mmr-061475	Microcebus murinus	48.81	2.00e-27	116.00
IUUC-Mdo-062077	Monodelphis domestica	71.88	8.00e-24	103.00
IUUC-Mmu-063984	Mus musculus	71.88	9.00e-24	104.00
IUUC-Mac-065175	Musa acuminata	43.31	6.00e-29	118.00
IUUC-Mpu-066751	Mustela putorius furo	43.07	2.00e-27	116.00
IUUC-Mlu-068234	Myotis lucifugus	71.88	1.00e-24	104.00
IUUC-Nfi-068541	Neosartorya fischeri	56.76	2.00e-30	123.00
IUUC-Ncr-068830	Neurospora crassa	71.05	1.00e-39	153.00
IUUC-Nle-069126	Nomascus leucogenys	71.88	1.00e-24	103.00
IUUC-Opr-070742	Ochotona princeps	50.60	9.00e-33	130.00
IUUC-Ont-071828	Oreochromis niloticus	71.88	4.00e-24	102.00
IUUC-Oan-073462	Ornithorhynchus anatinus	71.88	9.00e-24	104.00
IUUC-Ocu-074890	Oryctolagus cuniculus	64.06	6.00e-22	98.20
IUUC-Oba-075995	Oryza barthii	45.75	2.00e-29	119.00
IUUC-Obr-076073	Oryza brachyantha	46.41	1.00e-29	120.00
IUUC-Ogl-077445	Oryza glaberrima	45.75	2.00e-29	119.00
IUUC-Ogu-078606	Oryza glumaepatula	45.75	2.00e-29	119.00
IUUC-Oin-079287	Oryza indica	45.75	2.00e-29	119.00
IUUC-Olo-080686	Oryza longistaminata	36.36	6.00e-23	98.20
IUUC-Ome-081567	Oryza meridionalis	42.48	5.00e-27	111.00
IUUC-Oni-082873	Oryza nivara	45.75	2.00e-29	119.00
IUUC-Opu-083488	Oryza punctata	40.51	1.00e-25	107.00
IUUC-Oru-084592	Oryza rufipogon	45.75	2.00e-29	119.00
IUUC-Osa-086102	Oryza sativa	45.75	2.00e-29	119.00
IUUC-Ola-087531	Oryzias latipes	50.00	8.00e-33	131.00
IUUC-Olu-087895	Ostreococcus lucimarinus	36.60	5.00e-22	94.00
IUUC-Oga-088239	Otolemur garnettii	71.88	1.00e-24	104.00
IUUC-Oar-090371	Ovis aries	42.60	3.00e-27	115.00
IUUC-Ptr-090481	Pan troglodytes	44.24	1.00e-23	103.00
IUUC-Pan-092210	Papio anubis	46.34	9.00e-27	114.00
IUUC-Psi-093588	Pelodiscus sinensis	71.88	1.00e-24	104.00
IUUC-Pma-094702	Petromyzon marinus	71.88	2.00e-24	103.00
IUUC-Pno-094927	Phaeosphaeria nodorum	71.05	1.00e-37	147.00
IUUC-Ppa-095389	Physcomitrella patens	61.19	2.00e-21	93.20
IUUC-Pfo-096744	Poecilia formosa	51.83	5.00e-34	135.00
IUUC-Pab-098044	Pongo abelii	71.88	1.00e-24	104.00
IUUC-Pop-099938	Populus trichocarpa	46.41	1.00e-29	120.00
IUUC-Pca-100355	Procavia capensis	47.56	8.00e-27	114.00
IUUC-Ppe-101786	Prunus persica	43.95	1.00e-29	120.00
IUUC-Pva-102494	Pteropus vampyrus	71.88	1.00e-24	103.00
IUUC-Pgr-103303	Puccinia graminis	56.10	5.00e-21	91.70
IUUC-Ptt-103748	Puccinia triticina	70.45	2.00e-13	67.00
IUUC-Pte-104368	Pyrenophora teres	68.42	1.00e-36	144.00
IUUC-Pyt-104542	Pyrenophora triticirepentis	67.54	4.00e-36	142.00
IUUC-Rno-105387	Rattus norvegicus	71.88	1.00e-23	104.00
IUUC-Sce-106371	Saccharomyces cerevisiae	50.00	2.00e-17	79.70
IUUC-Sha-107189	Sarcophilus harrisii	71.88	1.00e-24	104.00
IUUC-Sja-107942	Schizosaccharomyces japonicus	55.41	3.00e-18	82.00
IUUC-Spo-108121	Schizosaccharomyces pombe	47.43	5.00e-32	128.00
IUUC-Smo-108783	Selaginella moellendorffii	50.30	6.00e-28	114.00
IUUC-Sit-109728	Setaria italica	47.06	6.00e-28	114.00
IUUC-Sly-110957	Solanum lycopersicum	58.82	2.00e-17	80.10
IUUC-Stu-112873	Solanum tuberosum	57.69	1.00e-16	77.00
IUUC-Sar-113668	Sorex araneus	72.97	2.00e-10	57.00
IUUC-Sbi-114223	Sorghum bicolor	57.69	9.00e-17	77.80
IUUC-Sre-115220	Sporisorium reilianum	44.44	8.00e-20	87.80
IUUC-Ssc-116119	Sus scrofa	71.88	1.00e-24	104.00
IUUC-Tgu-116528	Taeniopygia guttata	71.88	1.00e-24	103.00
IUUC-Tru-117538	Takifugu rubripes	71.88	1.00e-24	103.00
IUUC-Tsy-118855	Tarsius syrichta	72.97	2.00e-10	56.60
IUUC-Tni-120134	Tetraodon nigroviridis	50.00	6.00e-33	131.00
IUUC-Tca-121524	Theobroma cacao	47.93	3.00e-30	122.00
IUUC-Tre-121915	Trichoderma reesei	68.70	3.00e-37	145.00
IUUC-Tvi-122411	Trichoderma virens	68.47	4.00e-34	135.00
IUUC-Tae-124851	Triticum aestivum	47.06	2.00e-25	106.00
IUUC-Tur-126821	Triticum urartu	47.06	2.00e-25	106.00
IUUC-Tme-126875	Tuber melanosporum	68.70	5.00e-32	128.00
IUUC-Tbe-127759	Tupaia belangeri	66.04	2.00e-16	76.60
IUUC-Ttr-129124	Tursiops truncatus	46.30	5.00e-26	111.00
IUUC-Uma-129551	Ustilago maydis	57.33	2.00e-20	89.70
IUUC-Vda-129992	Verticillium dahliae	62.33	1.00e-52	196.00
IUUC-Vpa-130096	Vicugna pacos	70.31	8.00e-22	94.70
IUUC-Vvi-130940	Vitis vinifera	59.62	9.00e-16	74.30
IUUC-Xtr-132454	Xenopus tropicalis	46.56	1.00e-24	103.00
IUUC-Xma-133842	Xiphophorus maculatus	51.83	1.00e-33	134.00
IUUC-Yli-134485	Yarrowia lipolytica	56.92	3.00e-18	82.40
IUUC-Zma-135748	Zea mays	43.14	4.00e-27	112.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence