iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065759

Ensembl Protein ID

ENSMPUP00000012422.1

UniProt Accession

M3YM65; M3YM65_MUSPF

Genbank Protein ID

ENSMPUP00000012422

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01025171

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000012516.1	ENSMPUT00000012623.1	ENSMPUP00000012422.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-81	273.2	123	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS+LQcL+ +p+l+++ll+ +++++++     + + ++l+ +q+ + +   ++ +a++p ++++ lkk+a++f+  +q
   Q: 123  GLHNLGNTCFLNSTLQCLTYTPPLASYLLSkEHTRNCH-----QGSFCMLCLMQNHMVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQ 206
           9*****************************44444444.....457899999999999999**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++++d++++++                  l+  a+ + +++ ++l++++F+g l+s++kc  c++vs +++p ld+ l++++
   Q: 207  EDAHEFLRYIVDAMQKAC------------------LNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQ 277
           ******************..................344556788999***************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c kckkk+ a+k++++++ ++vL+l LkRf    ++ s  ki+k v +p+ L+++p++++
   Q: 278  AA-----NIVRALELFVKPDVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRF----ANFSGGKITKDVGYPEFLNIRPYMSQ 357
           **.....9***************************************************....668899******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds V++++ + vl+   ++aYvlfY 
   Q: 358  SSGE---PVMYGLYAVLVHSGySCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKVVLN---QQAYVLFYL 421
           5544...9**************************************************...********6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MPIVDKLKEA LKPGRKDSAD DGDLGKLLAS SAKKVLLQKI EFEPASKSFS YQLESLKSKY 60
VLLNPKTEGA SRHRSADEPQ SRRQGSEHAY ESGGDGVPAP QKVLFPTERL SLKWERVYRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCTGACGC CCCTTCGGGT CGACAGACTT GCAGCTTTGG TGATTTCATG GGGCGCAGCC 60
AAGGAGCTCA TGAACCGGAG GGTCCTGCCC TGCGTCTGCC CAGTCTGGCC GGAACCTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002092	Ailuropoda melanoleuca	85.68	0.00e+00	1615.00
IUUC-Atr-003102	Amborella trichopoda	40.53	4.00e-85	310.00
IUUC-Aca-005360	Anolis carolinensis	62.66	0.00e+00	902.00
IUUC-Aly-006389	Arabidopsis lyrata	39.14	2.00e-77	284.00
IUUC-Ath-006710	Arabidopsis thaliana	34.50	1.00e-78	288.00
IUUC-Bta-013047	Bos taurus	73.40	0.00e+00	1331.00
IUUC-Bdi-014036	Brachypodium distachyon	45.57	3.00e-85	310.00
IUUC-Bra-018046	Brassica rapa	37.63	6.00e-83	302.00
IUUC-Cja-019203	Callithrix jacchus	71.05	0.00e+00	1251.00
IUUC-Cfa-020586	Canis familiaris	84.96	0.00e+00	1664.00
IUUC-Cpo-021804	Cavia porcellus	64.41	0.00e+00	1182.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	47.30	3.00e-53	201.00
IUUC-Csa-023137	Chlorocebus sabaeus	73.09	0.00e+00	1350.00
IUUC-Cin-025230	Ciona intestinalis	53.17	2.00e-97	348.00
IUUC-Cne-027049	Cryptococcus neoformans	33.89	2.00e-39	157.00
IUUC-Cme-027339	Cyanidioschyzon merolae	37.75	7.00e-60	224.00
IUUC-Dre-028587	Danio rerio	72.61	0.00e+00	798.00
IUUC-Dno-029149	Dasypus novemcinctus	67.17	0.00e+00	1239.00
IUUC-Dor-030836	Dipodomys ordii	65.74	0.00e+00	950.00
IUUC-Dme-032119	Drosophila melanogaster	33.33	2.00e-71	264.00
IUUC-Ete-032567	Echinops telfairi	66.87	0.00e+00	826.00
IUUC-Eca-033600	Equus caballus	76.76	0.00e+00	1459.00
IUUC-Eeu-035206	Erinaceus europaeus	59.59	5.00e-147	515.00
IUUC-Fca-036392	Felis catus	71.29	0.00e+00	804.00
IUUC-Fal-036852	Ficedula albicollis	63.21	4.00e-159	555.00
IUUC-Gmo-039033	Gadus morhua	72.27	0.00e+00	784.00
IUUC-Gga-040664	Gallus gallus	76.49	0.00e+00	754.00
IUUC-Gac-042176	Gasterosteus aculeatus	68.12	0.00e+00	786.00
IUUC-Ggo-045437	Gorilla gorilla	73.27	0.00e+00	1323.00
IUUC-Hsa-046863	Homo sapiens	73.00	0.00e+00	1318.00
IUUC-Hvu-047714	Hordeum vulgare	38.96	4.00e-66	246.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	67.26	0.00e+00	1195.00
IUUC-Lch-050120	Latimeria chalumnae	60.53	0.00e+00	747.00
IUUC-Lpe-051574	Leersia perrieri	42.23	3.00e-79	290.00
IUUC-Loc-052796	Lepisosteus oculatus	71.04	0.00e+00	764.00
IUUC-Laf-054243	Loxodonta africana	67.94	0.00e+00	1254.00
IUUC-Mcc-055762	Macaca mulatta	72.74	0.00e+00	1317.00
IUUC-Meu-056697	Macropus eugenii	65.90	0.00e+00	1245.00
IUUC-Mtr-058537	Medicago truncatula	44.05	1.00e-85	311.00
IUUC-Mla-059049	Melampsora laricipopulina	41.28	9.00e-60	224.00
IUUC-Mga-059359	Meleagris gallopavo	78.43	4.00e-154	538.00
IUUC-Mmr-060966	Microcebus murinus	70.41	0.00e+00	1275.00
IUUC-Mdo-062733	Monodelphis domestica	63.68	0.00e+00	1196.00
IUUC-Mmu-064331	Mus musculus	65.87	0.00e+00	1208.00
IUUC-Mac-065039	Musa acuminata	40.10	1.00e-86	315.00
IUUC-Mlu-067371	Myotis lucifugus	66.79	0.00e+00	1239.00
IUUC-Nle-070087	Nomascus leucogenys	72.20	0.00e+00	1299.00
IUUC-Opr-070729	Ochotona princeps	65.30	0.00e+00	974.00
IUUC-Ont-071346	Oreochromis niloticus	77.69	0.00e+00	793.00
IUUC-Oan-072931	Ornithorhynchus anatinus	67.73	0.00e+00	865.00
IUUC-Ocu-074823	Oryctolagus cuniculus	61.23	0.00e+00	1061.00
IUUC-Oba-075866	Oryza barthii	45.08	9.00e-84	305.00
IUUC-Obr-076408	Oryza brachyantha	43.53	3.00e-85	310.00
IUUC-Ogl-077239	Oryza glaberrima	45.25	2.00e-84	307.00
IUUC-Ogu-078064	Oryza glumaepatula	45.25	2.00e-84	307.00
IUUC-Oin-079157	Oryza indica	45.25	2.00e-84	307.00
IUUC-Olo-080231	Oryza longistaminata	43.35	2.00e-76	280.00
IUUC-Ome-081746	Oryza meridionalis	45.75	2.00e-83	303.00
IUUC-Oni-082339	Oryza nivara	45.25	2.00e-84	307.00
IUUC-Opu-083194	Oryza punctata	42.08	4.00e-84	307.00
IUUC-Oru-085083	Oryza rufipogon	45.25	2.00e-84	307.00
IUUC-Osa-086180	Oryza sativa	45.25	2.00e-84	307.00
IUUC-Ola-087255	Oryzias latipes	62.90	0.00e+00	798.00
IUUC-Olu-087773	Ostreococcus lucimarinus	45.57	2.00e-71	262.00
IUUC-Oga-088818	Otolemur garnettii	71.57	0.00e+00	1128.00
IUUC-Oar-089410	Ovis aries	70.50	0.00e+00	1292.00
IUUC-Ptr-090680	Pan troglodytes	74.15	0.00e+00	1154.00
IUUC-Pan-092482	Papio anubis	72.74	0.00e+00	1338.00
IUUC-Ppa-095853	Physcomitrella patens	47.77	2.00e-92	333.00
IUUC-Pfo-096807	Poecilia formosa	63.79	0.00e+00	816.00
IUUC-Pab-098724	Pongo abelii	72.94	0.00e+00	1351.00
IUUC-Pop-099693	Populus trichocarpa	45.93	3.00e-82	300.00
IUUC-Pca-100117	Procavia capensis	75.95	4.00e-153	535.00
IUUC-Ppe-101678	Prunus persica	35.36	3.00e-82	300.00
IUUC-Pva-102883	Pteropus vampyrus	64.90	0.00e+00	1030.00
IUUC-Pgr-103270	Puccinia graminis	45.94	1.00e-68	254.00
IUUC-Ptt-103887	Puccinia triticina	44.65	7.00e-69	254.00
IUUC-Rno-105340	Rattus norvegicus	66.91	0.00e+00	1022.00
IUUC-Sha-107019	Sarcophilus harrisii	64.01	0.00e+00	1230.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	42.90	6.00e-79	287.00
IUUC-Spo-108119	Schizosaccharomyces pombe	46.20	6.00e-84	304.00
IUUC-Sit-110536	Setaria italica	45.57	2.00e-79	290.00
IUUC-Sly-111722	Solanum lycopersicum	39.68	3.00e-80	293.00
IUUC-Stu-112912	Solanum tuberosum	39.66	8.00e-81	295.00
IUUC-Sbi-114477	Sorghum bicolor	45.57	2.00e-86	313.00
IUUC-Sre-114924	Sporisorium reilianum	40.36	1.00e-65	244.00
IUUC-Ssc-116022	Sus scrofa	70.98	0.00e+00	1174.00
IUUC-Tgu-116976	Taeniopygia guttata	71.36	7.00e-161	560.00
IUUC-Tru-118391	Takifugu rubripes	63.57	0.00e+00	808.00
IUUC-Tsy-119253	Tarsius syrichta	56.85	0.00e+00	775.00
IUUC-Tni-120064	Tetraodon nigroviridis	78.30	0.00e+00	793.00
IUUC-Tca-120936	Theobroma cacao	38.20	2.00e-84	307.00
IUUC-Tae-125259	Triticum aestivum	48.26	1.00e-88	322.00
IUUC-Tur-126014	Triticum urartu	47.39	2.00e-84	307.00
IUUC-Tbe-127377	Tupaia belangeri	61.32	0.00e+00	769.00
IUUC-Ttr-129259	Tursiops truncatus	82.69	0.00e+00	763.00
IUUC-Uma-129416	Ustilago maydis	41.19	1.00e-67	251.00
IUUC-Vpa-130568	Vicugna pacos	65.81	6.00e-44	172.00
IUUC-Xtr-132944	Xenopus tropicalis	76.78	0.00e+00	676.00
IUUC-Xma-133735	Xiphophorus maculatus	62.95	0.00e+00	814.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence