iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.90e-06	26.3	381	405

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd.tllvsGsdDgtikvWDl 30
           ++++ ++ +ll++Gs  g++ ++D+
   Q: 381  SIQLsPNqRLLATGSQEGVVNIYDY 405
           466687779***************6 PP

Organism

Drosophila melanogaster

Functional Description
(View)

Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA. Regulation of cell size by ribosome synthesis is an important parameter for stem cell maintenance and function.

Protein Sequence
(Fasta)

MSSDESSDGL EELQSLKALY GQQEQEKPAK IKRERYIPKA SQAKELNYVE VPMEKVLFGD 60
RQRLLTNLAK SVGQKLPNDD EDEQEENPGQ AKPGDKRKAA WSDSDDEDLQ VGDVKKATKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAAAGCGTT AGTCGATTTC CCGCCCAGCT GCACGTGTAT ATTTTTTTGC GGTCCAAAGA 60
AAAGTTCGTA AATAAACGAA TTTGCGTGCA TTTCCAGCGA ACACGATGAG TTCAGACGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR023302--Pept_S9A_N
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0042585--C:germinal vesicle
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0030532--C:small nuclear ribonucleoprotein complex
GO:0032040--C:small-subunit processome
GO:0048132--P:female germ-line stem cell asymmetric division
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0007405--P:neuroblast proliferation
GO:0022008--P:neurogenesis
GO:0006364--P:rRNA processing

KEGG

dme:Dmel_CG7989

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000184	Aegilops tauschii	28.41	3.00e-47	182.00
IUUC-Aml-002252	Ailuropoda melanoleuca	32.84	9.00e-56	210.00
IUUC-Atr-002575	Amborella trichopoda	31.67	3.00e-50	192.00
IUUC-Aly-006512	Arabidopsis lyrata	29.10	2.00e-49	189.00
IUUC-Ath-007244	Arabidopsis thaliana	29.33	2.00e-45	176.00
IUUC-Ago-007895	Ashbya gossypii	25.23	9.00e-26	110.00
IUUC-Acl-008343	Aspergillus clavatus	24.95	2.00e-29	123.00
IUUC-Afl-008445	Aspergillus flavus	24.95	2.00e-32	133.00
IUUC-Aor-009986	Aspergillus oryzae	24.95	3.00e-31	129.00
IUUC-Ame-011338	Astyanax mexicanus	30.15	9.00e-53	200.00
IUUC-Bgr-012201	Blumeria graminis	24.54	6.00e-26	111.00
IUUC-Bta-013058	Bos taurus	33.08	2.00e-54	206.00
IUUC-Bci-013619	Botrytis cinerea	25.11	4.00e-35	142.00
IUUC-Bdi-014771	Brachypodium distachyon	28.24	5.00e-46	177.00
IUUC-Bol-015230	Brassica oleracea	31.80	7.00e-44	171.00
IUUC-Bra-017041	Brassica rapa	32.05	6.00e-45	174.00
IUUC-Cel-018293	Caenorhabditis elegans	27.75	4.00e-41	161.00
IUUC-Cja-019503	Callithrix jacchus	33.33	6.00e-54	204.00
IUUC-Cfa-020743	Canis familiaris	32.84	2.00e-57	215.00
IUUC-Cpo-021488	Cavia porcellus	30.71	3.00e-51	195.00
IUUC-Cre-022926	Chlamydomonas reinhardtii	26.55	2.00e-37	149.00
IUUC-Csa-023110	Chlorocebus sabaeus	31.65	3.00e-53	202.00
IUUC-Cin-025208	Ciona intestinalis	33.23	2.00e-50	192.00
IUUC-Cme-027351	Cyanidioschyzon merolae	27.30	6.00e-26	111.00
IUUC-Dre-027524	Danio rerio	26.43	7.00e-36	144.00
IUUC-Dno-029243	Dasypus novemcinctus	32.59	9.00e-54	203.00
IUUC-Dor-030110	Dipodomys ordii	34.44	5.00e-50	191.00
IUUC-Dse-031217	Dothistroma septosporum	24.63	2.00e-22	100.00
IUUC-Eca-034350	Equus caballus	33.58	6.00e-53	201.00
IUUC-Eeu-034991	Erinaceus europaeus	33.77	2.00e-49	189.00
IUUC-Fal-036614	Ficedula albicollis	31.67	6.00e-50	191.00
IUUC-Gmo-039183	Gadus morhua	34.86	2.00e-52	199.00
IUUC-Gga-040922	Gallus gallus	30.71	1.00e-58	219.00
IUUC-Gac-041475	Gasterosteus aculeatus	33.33	2.00e-51	196.00
IUUC-Gma-043598	Glycine max	28.69	2.00e-49	189.00
IUUC-Ggo-044517	Gorilla gorilla	31.79	6.00e-55	207.00
IUUC-Hsa-045741	Homo sapiens	31.79	7.00e-55	207.00
IUUC-Hvu-047463	Hordeum vulgare	29.24	2.00e-18	84.30
IUUC-Itr-048128	Ictidomys tridecemlineatus	31.22	2.00e-54	205.00
IUUC-Kpa-049335	Komagataella pastoris	27.62	7.00e-32	130.00
IUUC-Lch-049816	Latimeria chalumnae	32.65	4.00e-52	198.00
IUUC-Lpe-051140	Leersia perrieri	29.32	2.00e-49	189.00
IUUC-Loc-051942	Lepisosteus oculatus	33.68	1.00e-54	206.00
IUUC-Laf-054245	Loxodonta africana	33.05	2.00e-56	212.00
IUUC-Meu-056300	Macropus eugenii	30.21	7.00e-42	163.00
IUUC-Mor-057184	Magnaporthe oryzae	23.26	2.00e-27	116.00
IUUC-Mtr-058019	Medicago truncatula	28.57	7.00e-47	181.00
IUUC-Mga-060179	Meleagris gallopavo	32.19	4.00e-56	211.00
IUUC-Mvi-060435	Microbotryum violaceum	27.94	2.00e-37	150.00
IUUC-Mdo-062187	Monodelphis domestica	32.98	2.00e-51	196.00
IUUC-Mmu-063386	Mus musculus	31.83	5.00e-53	201.00
IUUC-Mpu-066084	Mustela putorius furo	34.54	4.00e-55	208.00
IUUC-Mlu-068130	Myotis lucifugus	30.59	9.00e-52	197.00
IUUC-Nle-069743	Nomascus leucogenys	28.63	2.00e-45	176.00
IUUC-Opr-071111	Ochotona princeps	33.72	2.00e-53	202.00
IUUC-Ont-071979	Oreochromis niloticus	34.74	6.00e-56	211.00
IUUC-Ocu-073754	Oryctolagus cuniculus	34.46	1.00e-55	209.00
IUUC-Oba-075007	Oryza barthii	29.60	2.00e-50	192.00
IUUC-Obr-076447	Oryza brachyantha	29.31	3.00e-51	195.00
IUUC-Ogl-077733	Oryza glaberrima	29.60	1.00e-50	193.00
IUUC-Ogu-078828	Oryza glumaepatula	30.09	6.00e-51	194.00
IUUC-Oin-080152	Oryza indica	30.09	3.00e-51	195.00
IUUC-Olo-080983	Oryza longistaminata	30.09	3.00e-50	192.00
IUUC-Oni-082443	Oryza nivara	30.09	9.00e-51	194.00
IUUC-Opu-083771	Oryza punctata	29.51	8.00e-48	184.00
IUUC-Oru-084272	Oryza rufipogon	30.09	5.00e-51	194.00
IUUC-Osa-085885	Oryza sativa	30.22	1.00e-52	200.00
IUUC-Olu-087644	Ostreococcus lucimarinus	21.66	6.00e-09	54.30
IUUC-Oga-088834	Otolemur garnettii	34.21	1.00e-53	203.00
IUUC-Oar-089712	Ovis aries	33.08	5.00e-54	204.00
IUUC-Pan-092561	Papio anubis	31.86	8.00e-53	200.00
IUUC-Ppa-095397	Physcomitrella patens	31.46	5.00e-48	184.00
IUUC-Pfo-097068	Poecilia formosa	35.29	4.00e-58	218.00
IUUC-Pop-099471	Populus trichocarpa	29.51	2.00e-48	186.00
IUUC-Ppe-101446	Prunus persica	33.13	2.00e-48	186.00
IUUC-Pva-102851	Pteropus vampyrus	30.38	6.00e-49	187.00
IUUC-Pgr-103370	Puccinia graminis	27.84	3.00e-36	145.00
IUUC-Ptt-103838	Puccinia triticina	27.84	5.00e-32	131.00
IUUC-Rno-104910	Rattus norvegicus	32.90	6.00e-53	201.00
IUUC-Sce-106258	Saccharomyces cerevisiae	25.21	1.00e-28	120.00
IUUC-Sja-107746	Schizosaccharomyces japonicus	25.81	3.00e-37	148.00
IUUC-Spo-108268	Schizosaccharomyces pombe	27.31	7.00e-43	167.00
IUUC-Smo-108815	Selaginella moellendorffii	29.14	3.00e-51	195.00
IUUC-Sit-109706	Setaria italica	30.60	2.00e-45	175.00
IUUC-Sly-111533	Solanum lycopersicum	29.07	2.00e-50	192.00
IUUC-Stu-112853	Solanum tuberosum	28.41	6.00e-51	194.00
IUUC-Sbi-114747	Sorghum bicolor	30.30	5.00e-48	184.00
IUUC-Ssc-115916	Sus scrofa	34.87	5.00e-57	214.00
IUUC-Tgu-117291	Taeniopygia guttata	33.13	1.00e-51	196.00
IUUC-Tru-118724	Takifugu rubripes	32.79	3.00e-62	231.00
IUUC-Tsy-118928	Tarsius syrichta	38.14	3.00e-39	155.00
IUUC-Tca-121229	Theobroma cacao	30.00	2.00e-53	202.00
IUUC-Tae-123641	Triticum aestivum	28.41	2.00e-46	179.00
IUUC-Tur-126082	Triticum urartu	25.94	1.00e-26	112.00
IUUC-Ttr-128904	Tursiops truncatus	35.36	1.00e-44	173.00
IUUC-Vpa-130817	Vicugna pacos	31.52	3.00e-57	215.00
IUUC-Vvi-131395	Vitis vinifera	32.08	9.00e-52	197.00
IUUC-Xtr-132971	Xenopus tropicalis	30.75	1.00e-53	203.00
IUUC-Xma-133391	Xiphophorus maculatus	35.00	3.00e-58	218.00
IUUC-Yli-134613	Yarrowia lipolytica	26.73	8.00e-38	150.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence